Regulation of poly-(R)-(3-hydroxybutyrate-co-3-hydroxyvalerate) biosynthesis by the AtoSCDAEB regulon in phaCAB + Escherichia coli

Applied Microbiology and Biotechnology

Volumn 97, Issue 12, 2013, Pages 5259-5274

  Theodorou, Evangelos C ^a   Theodorou, Marina C ^a,b   Kyriakidis, Dimitrios A ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Oxidation; atoDAEB; AtoSC; Fatty acid biosynthesis; Poly (R) (3 hydroxybutyrate co 3 hydroxyvalerate); Two component system

Indexed keywords

ATODAEB; ATOSC; FATTY ACID BIOSYNTHESIS; POLY-(R)-(3-HYDROXYBUTYRATE-CO-3-HYDROXYVALERATE); TWO COMPONENT SYSTEMS;

BIODEGRADATION; BIOMOLECULES; BIOSYNTHESIS; COPOLYMERS; ESCHERICHIA COLI; METABOLISM; ORGANIC ACIDS;

BIOCHEMISTRY;

ACRYLIC ACID; CERULENIN; COPOLYMER;

BIOTECHNOLOGY; CHROMOSOME; COLIFORM BACTERIUM; FATTY ACID; FRACTIONATION; INHIBITION; ORGANIC COMPOUND; PERCEPTION; PHENOTYPE; POLYMER;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG SYNTHESIS; ESCHERICHIA COLI; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE DELETION; NONHUMAN; PHENOTYPE; REGULON; SIGNAL TRANSDUCTION; UPREGULATION;

ACETOACETATES; CUPRIAVIDUS NECATOR; ESCHERICHIA COLI; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; METABOLIC ENGINEERING; POLYESTERS; RECOMBINANT PROTEINS; REGULON; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

CUPRIAVIDUS NECATOR; ESCHERICHIA COLI;

EID: 84878733144     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-4843-8     Document Type: Article

References (52)

1. Brandl H (1993) Proceedings of the international symposium on bacterial polyhydroxyalkanoates ISBP'92, Schegel H.G. Steinbüchel A. (ed.)
2. Brandl H, Gross RA, Lenz RW, Fuller RC (1988) Pseudomonas oleovorans as a source of poly(β-hydroxyalkanoates) for potential application as biodegradable polyesters. Appl Environ Microbiol 54:1977-1982
3. Canellakis ES, Paterakis AA, Huang SC, Panagiotidis CA, Kyriakidis DA (1993) Identification, cloning, and nucleotide sequencing of the ornithine decarboxylase antizyme gene of Escherichia coli. Proc Natl Acad Sci USA 90:7129-7133
4. Clark DP, Cronan JE Jr (1996) Two-carbon compounds and fatty acids as carbon sources. In: Neidhardt FC (ed) Escherichia coli and Salmonella typhimurium (cellular and molecular biology). American Society of Microbiology, Washington DC
5. Fidler S, Dennis D (1992) Polyhydroxyalkanoate production in recombinant Escherichia coli. FEMS Microbiol Rev 103:231-236
6. Filippou PS, Kasemian LD, Panagiotidis CA, Kyriakidis DA (2008) Functional characterization of the histidine kinase of the E. coli two-component signal transduction system AtoS-AtoC. Biochim Biophys Acta 1780:1023-1031
7. Fujita Y, Matsuoka H, Hirookam K (2007) Regulation of fatty acid metabolism in bacteria. Mol Microbiol 66:829-839
8. Fukui T, Yokomizo S, Kobayashi G, Doi Y (1999) Co-expression of polyhydroxyalkanoate synthase and (R)-enoyl-CoA hydratase genes from Aeromonas caviae establishes copolyester biosynthesis pathway in Escherichia coli. FEMS Microbiol Lett 170:69-75
9. Funabashi H, Kawaguchi A, Tomoda H, Omura S, Okuda S, Iwasaki S (1989) Binding site of cerulenin in fatty acid synthetase. J Biochem 105:751-755
10. Grage K, Jahns AC, Parlane N, Palanisamy R, Rasiah IA, Atwood JA, Rehm BHA (2009) Bacterial polyhydroxyalkanoate granules: biogenesis, structure, and potential use as nano-/micro-beads in biotechnological and biomedical applications. Biomacromol 10:660-669
11. Griffo G, Oppenheim AB, Gottesman ME (1989) Repression of the lambda pcin promoter by integrative host factor. J Mol Biol 209:55-64
12. Grigoroudis AI, Panagiotidis CA, Lioliou EE, Vlassi M, Kyriakidis DA (2007) Molecular modeling and functional analysis of the AtoS-AtoC two-component signal transduction system of Escherichia coli. Biochim Biophys Acta 1770:1248-1258
13. Hazer B, Steinbüchel A (2007) Increased diversification of polyhydroxyalkanoates by modification reactions for industrial and medical applications. Appl Microbiol Biotechnol 74:1-12
14. Jung YK, Lee SY, Tam TT (2011) Plastics from bacteria: natural functions and applications, towards systems metabolic engineering of PHA producers. In: Chen G-Q (ed) Microbiology monographs, vol 14. Springer, Berlin
15. Kessler B, Witholt B (2001) Factors involved in the regulatory network of polyhydroxyalkanoate metabolism. J Biotechno 86:97-104
16. Klinke S, Ren Q, Witholt B, Kessler B (1999) Production of medium-chain-length poly(3-hydroxyalkanoates) from gluconate by recombinant Escherichia coli. Appl Environ Microbiol 65:540-548
17. Kyriakidis DA, Tiligada E (2009) Signal transduction and adaptive regulation through bacterial two-component systems: the Escherichia coli AtoSC paradigm. Amino Acids 37:443-458
18. Kyriakidis DA, Theodorou MC, Filippou PS, Kyriakidis KD, Tiligada E (2008) Effect of histamine on the signal transduction of the AtoS-AtoC two component system and involvement in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli. Amino Acids 35:45-52
19. Lee SY (1996) Bacterial polyhydroxyalkanoates. Biotechnol Bioeng 49:1-14
20. Li R, Zhang H, Qi Q (2007) The production of polyhydroxyalkanoates in recombinant Escherichia coli. Biores Techn 98:2313-2320
21. Li Z-J, Shi Z-Y, Jian J, Guo Y-Y, Wu Q, Chen G-Q (2010) Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from unrelated carbon sources by metabolically engineered Escherichia coli. Metab Eng 12:352-359
22. Lioliou EE, Mimitou EP, Grigoroudis AI, Panagiotidis CH, Panagiotidis CA, Kyriakidis DA (2005) Phosphorylation activity of the response regulator of the two-component signal transduction system AtoS-AtoC in E. coli. Biochim Biophys Acta 1725:257-268
23. Liu SJ, Steinbüchel A (2000) A novel genetically engineered pathway for synthesis of poly(hydroxyalkanoic acids) in Escherichia coli. Appl Environ Microbiol 66:739-743
24. Matsumoto K, Takase K, Yamamoto Y, Doi Y, Taguchi S (2009) Chimeric enzyme composed of polyhydroxyalkanoate (PHA) synthases from Ralstonia eutropha and Aeromonas caviae enhances production of PHAs in recombinant Escherichia coli. Biomacromol 10:682-685
25. Matta MK, Lioliou EE, Panagiotidis CH, Kyriakidis DA, Panagiotidis CA (2007) Interactions of the antizyme AtoC with regulatory elements of the Escherichia coli atoDAEB operon. J Bacteriol 189:6324-6332
26. Oshima T, Aiba H, Masuda Y, Kanaya S, Masahito S, Wanner BL, Mori H, Mizuno T (2002) Transcriptome analysis of all two component regulatory system mutants of Escherichia coli K-12. Mol Microbiol 46:281-291
27. Park SJ, Lee SY (2003) Identification and characterization of a new enoyl coenzyme A hydratase involved in biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant Escherichia coli. J Bacteriol 185:5391-5397
28. Park SJ, Ahn WS, Green PR, Lee SY (2001) Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains. Biotechnol Bioeng 74:81-86
29. Park SJ, Choi JI, Lee SY (2004) Engineering of Escherichia coli fatty acid metabolism for the production of polyhydroxyalkanoates. Enzyme Microb Technol 36:579-588
30. Prieto MA, Kellerhals MB, Bozzato GB, Radnovik D, Witholt B, Kessler B (1999) Engineering of stable recombinant bacteria for production of chiral medium-chain-length poly-3-hydroxyalkanoates. Appl Environ Microbiol 65:3265-3271
31. Rehm BHA (2003) Polyester synthases: natural catalysts for plastics. Biochem J 376:15-33
32. Reusch RN, Shabalin O, Crumbaugh A, Wagner R, Schröder O, Wurm R (2002) Posttranslational modification of E. coli histone-like protein H-NS and bovine histones by short-chain poly-(R)-3-hydroxybutyrate (cPHB). FEBS Lett 527:319-322
33. + Escherichia coli. Appl Environ Microbiol 61:2487-2492
34. Sambrook J, Fitsch EF, Maniatis T (1989) In Cold Spring Harbor Press (ed) Molecular cloning: a laboratory manual. Cold Spring Harbor
35. Schubert P, Steinbüchel A, Schlegel HG (1988) Cloning of the Alcaligenes eutrophus poly-b-hydroxybutyrate synthetic pathway and synthesis of P(3HB) in Escherichia coli. J Bacteriol 170:5837-5847
36. Slater S, Gallaher T, Dennis D (1992) Production of poly-(3- hydroxybutyrate-co-3-hydroxyvalerate) in a recombinant Escherichia coli strain. Appl Environ Microbiol 58:1089-1094
37. Slater S, Houmiel KL, Tran M, Mitsky TA, Taylor NB, Padgette SR, Gruys KJ (1998) Cloning and expression in Escherichia coli of the Alcaligens eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway. J Bacteriol 180:1979-1987
38. Spiekermann R, Rehm BHA, Karlscheuer R, Baumeister D, Steinbüchel A (1999) A sensitive, viable-colony staining method using Nile Red for direct screening of bacteria that accumulate polyhydroxyalkanoic acids and other lipid storage compounds. Arch Microbiol 171:73-80
39. Suriyamongkol P, Weselake R, Narine S, Moloney M, Shah S (2007) Biotechnological approaches for the production of polyhydroxyalkanoates in microorganisms and plants - a review. Biotechnol Adv 25:148-175
40. Theodorou MC, Panagiotidis CA, Panagiotidis CH, Pantazaki AA, Kyriakidis DA (2006) Involvement of the AtoS-AtoC signal transduction system in poly-(R)-3-hydroxybutyrate biosynthesis in Escherichia coli. Biochim Biophys Acta 1760:896-906
41. Theodorou MC, Theodorou EC, Panagiotidis CA, Kyriakidis DA (2007) Spermidine triggering effect to the signal transduction through the AtoS-AtoC/Az two component system in Escherichia coli. Biochim Biophys Acta 1770:1104-1114
42. 2+ transients affect poly-(R)-3-hydroxybutyrate regulation by the AtoS-AtoC system in E. coli. Biochem J 417:667-672
43. Theodorou EC, Theodorou MC, Kyriakidis DA (2011a) AtoSC two-component system is involved in cPHB biosynthesis through fatty acid metabolism in E. coli. Biochim Biophys Acta 1810:561-568
44. Theodorou EC, Theodorou MC, Samali MN, Kyriakidis DA (2011b) Activation of the AtoSC two component system in the absence of the AtoC N-terminal receiver domain in E. coli. Amino Acids 40:421-430
45. + Escherichia coli. Metab Eng 14:354-365
46. Theodorou MC, Theodorou EC, Kyriakidis DA (2012b) Involvement of AtoSC two-component system in Escherichia coli flagellar regulon. Amino Acids 43:833-844
47. Tsao C-Y, Hooshangi S, Wu H-C, Valdes JJ, Bentley WE (2010) Autonomous induction of recombinant proteins by minimally rewiring native quorum sensing regulon of E. coli. Metab Eng 12:291-297
48. Tyo KEJ, Fischer CR, Simeon F, Stephanopoulos G (2010) Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations. Metab Eng 12:187-195
49. Wong MS, Causey TB, Mantzaris N, Bennett GN, San KY (2008) Engineering poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolymer composition in E. coli. Biotechnol Bioeng 99:919-928
50. Xian M, Fuerst MM, Shabalin Y, Reusch RN (2007) Sorting signal of Escherichia coli OmpA is modified by oligo-(R)-3-hydroxybutyrate. Biochim Biophys Acta 1768:2660-2666
51. Yim KS, Lee SY, Chang HN (1996) Synthesis of poly-(3-hydroxybutyrate-co- 3-hydroxyvalerate) by recombinant Escherichia coli. Biotechnol Bioeng 49:495-503
52. Zhou Q, Shi Z-Y, Meng D-C, Wu Q, Chen J-C, Chen G-Q (2011) Production of 3-hydroxypropionate homopolymer and poly(3-hydroxypropionate-co-4- hydroxybutyrate) copolymer by recombinant Escherichia coli. Metab Eng 13:777-785