Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations

Metabolic Engineering

Volumn 12, Issue 3, 2010, Pages 187-195

  Tyo, Keith E J ^a   Fischer, Curt R ^a   Simeon, Fritz ^a   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Chemostat; Flux control; Overexpression; PHB; Poly 3 hydroxybutyrate

Indexed keywords

DRY CELLS; EXPRESSION LEVELS; FLUX CONTROL; IN-VITRO; METABOLIC ENGINEERING; METABOLIC MODELS; OVER-EXPRESSION; PHB; POLY-3-HYDROXYBUTYRATE; POLYHYDROXYBUTYRATE; PRODUCT-FORMING PATHWAY; TOXIC EFFECT;

ESCHERICHIA COLI; GENE EXPRESSION; GROWTH RATE; METABOLISM;

CHEMOSTATS;

ACETOACETYL COENZYME A REDUCTASE; NITROGEN; POLY(3 HYDROXYBUTYRIC ACID); UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL STRAIN; CHEMOSTAT; ESCHERICHIA COLI; GENE EXPRESSION; GLUCOSE METABOLISM; GROWTH RATE; NONHUMAN; PHAA GENE; PHAB GENE; PHAEC GENE; PLASMID; PRECURSOR; PRIORITY JOURNAL;

3-HYDROXYBUTYRIC ACID; ALCOHOL OXIDOREDUCTASES; BIOCHEMICAL PROCESSES; CARBON; ESCHERICHIA COLI; GENE EXPRESSION; HYDROXYBUTYRATES; MODELS, BIOLOGICAL; PHYSICAL PROCESSES; POLYESTERS; RESEARCH;

ESCHERICHIA COLI;

EID: 77950858901     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2009.10.005     Document Type: Article

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