Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

EMBO Reports

Volumn 14, Issue 6, 2013, Pages 520-526

  Singhal, Ankita ^a   Ostermaier, Martin K ^a   Vishnivetskiy, Sergey A ^b   Panneels, Valérie ^a   Homan, Kristoff T ^c   Tesmer, John J G ^c   Veprintsev, Dmitry ^a   Deupi, Xavier ^a   Gurevich, Vsevolod V ^b   Schertler, Gebhard F X ^a,d   Standfuss, Joerg ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d ETH ZURICH   (Switzerland)

Author keywords

biased signalling; congenital stationary night blindness; G protein coupled receptors; retinitis pigmentosa; rhodopsin

Indexed keywords

G90D RHODOPSIN; RETINA S ANTIGEN; RHODOPSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONGENITAL BLINDNESS; CONGENITAL STATIONARY NIGHT BLINDNESS; CRYSTALLIZATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RETINA ROD; THERMOSTABILITY;

ARRESTIN; CRYSTALLOGRAPHY, X-RAY; EYE DISEASES, HEREDITARY; GENETIC DISEASES, X-LINKED; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MUTATION, MISSENSE; MYOPIA; NIGHT BLINDNESS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RHODOPSIN; SCHIFF BASES; STRUCTURAL HOMOLOGY, PROTEIN; TRANSITION TEMPERATURE;

EID: 84878582491     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2013.44     Document Type: Article

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