Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin

Journal of Neuroscience

Volumn 28, Issue 45, 2008, Pages 11662-11672

  Dizhoor, Alexander M ^a   Woodruff, Michael L ^b   Olshevskaya, Elena V ^a   Cilluffo, Marianne C ^c   Cornwall, M Carter ^d   Sieving, Paul A ^e,f   Fain, Gordon L ^b,g  

^a SALUS UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL EYE INSTITUTE   (United States)

^f NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^g JULES STEIN EYE INSTITUTE   (United States)

Author keywords

Adaptation; Photoreceptor; Rhodopsin; Rod; Transduction; Vision

Indexed keywords

11 CIS RETINAL; MUTANT PROTEIN; OPSIN; RHODOPSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HETEROZYGOSITY; HOMOZYGOSITY; LIPID VESICLE; MOUSE; NIGHT BLINDNESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RETINA ROD; SIGNAL TRANSDUCTION;

ANIMALS; ASPARTIC ACID; CALCIUM; CARRIER PROTEINS; DARK ADAPTATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; EYE PROTEINS; GLYCINE; KINETICS; LIGHT SIGNAL TRANSDUCTION; MEMBRANE POTENTIALS; MICE; MICE, TRANSGENIC; MUTATION; NIGHT BLINDNESS; OPSINS; PHOTIC STIMULATION; RETINAL ROD PHOTORECEPTOR CELLS; RETINALDEHYDE; RHODOPSIN; SPECTRUM ANALYSIS; TIME FACTORS;

EID: 58149267461     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4006-08.2008     Document Type: Article

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