Constitutive "light" adaptation in rods from G90D rhodopsin: A mechanism for human congenital nightblindness without rod cell loss

Journal of Neuroscience

Volumn 21, Issue 15, 2001, Pages 5449-5460

  Sieving, Paul A ^a,c   Fowler, Michael L ^a   Bush, Ronald A ^a   Machida, Shigeki ^a   Calvert, Peter D ^b   Green, Daniel G ^a   Makino, Clint L ^b   McHenry, Christina L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Congenital nightblindness; Constitutive activity; Light adaptation; Photoresponse; Retinal degeneration; Rhodopsin; Rod photoreceptor; Transgenic mouse

Indexed keywords

RHODOPSIN;

ANIMAL TISSUE; ARTICLE; CELL DEATH; LIGHT ADAPTATION; MOUSE; NIGHT BLINDNESS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RETINA ROD; TRANSGENIC MOUSE;

EID: 0035425947     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-15-05449.2001     Document Type: Article

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