New quinazoline derivatives for telomeric G-quadruplex DNA: Effects of an added phenyl group on quadruplex binding ability

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 1-13

  He, Jin Hui ^a   Liu, Hui Yun ^a   Li, Zeng ^a   Tan, Jia Heng ^a   Ou, Tian Miao ^a   Huang, Shi Liang ^a   An, Lin Kun ^a   Li, Ding ^a   Gu, Lian Quan ^a   Huang, Zhi Shu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Inducing ability; Quinazoline derivatives; Telomerase inhibitor; Telomere shortening; Telomeric G quadruplex DNA

Indexed keywords

DNA; N [2 (QUINAZOLIN 2 YL)PHENYL]BENZAMIDE; QUINAZOLINE DERIVATIVE; TELOMERASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG BINDING; HYDROGEN BOND;

BINDING, COMPETITIVE; CELL AGING; CELL SURVIVAL; CIRCULAR DICHROISM; DNA; G-QUADRUPLEXES; HL-60 CELLS; HUMANS; KINETICS; LIGANDS; MOLECULAR STRUCTURE; PHENOL; QUINAZOLINES; SURFACE PLASMON RESONANCE; TELOMERASE; TELOMERE; TELOMERE SHORTENING;

EID: 84878576998     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.01.051     Document Type: Article

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