Aminoacyl-anthraquinone conjugates as telomerase inhibitors: Synthesis, biophysical and biological evaluation

Journal of Medicinal Chemistry

Volumn 51, Issue 18, 2008, Pages 5566-5574

  Zagotto, Giuseppe ^a   Sissi, Claudia ^a   Lucatello, Lorena ^a   Pivetta, Claudia ^a   Cadamuro, Sergio A ^a   Fox, Keith R ^b   Neidle, Stephen ^c   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAQUINONE DERIVATIVE; TELOMERASE; TELOMERASE INHIBITOR;

ARTICLE; CANCER CELL CULTURE; CELL AGING; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR STABILITY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TELOMERE;

ANTHRAQUINONES; BIOPHYSICS; CELL AGING; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; FLUORESCENCE; HELA CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; TELOMERASE;

EID: 52449117457     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800160v     Document Type: Article

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