-
1
-
-
0027074439
-
Antimalarial drug resistance: the pace quickens
-
White NJ, (1992) Antimalarial drug resistance: the pace quickens. J Antimicrob Chemother 30: 571-585.
-
(1992)
J Antimicrob Chemother
, vol.30
, pp. 571-585
-
-
White, N.J.1
-
2
-
-
84860672426
-
Malaria drug resistance: new observations and developments
-
Sa JM, Chong JL, Wellems TE, (2011) Malaria drug resistance: new observations and developments. Essays Biochem 51: 137-160.
-
(2011)
Essays Biochem
, vol.51
, pp. 137-160
-
-
Sa, J.M.1
Chong, J.L.2
Wellems, T.E.3
-
3
-
-
84856679687
-
Global malaria mortality between 1980 and 2010: a systematic analysis
-
Murray CJ, Rosenfeld LC, Lim SS, Andrews KG, Foreman KJ, et al. (2012) Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet 379: 413-431.
-
(2012)
Lancet
, vol.379
, pp. 413-431
-
-
Murray, C.J.1
Rosenfeld, L.C.2
Lim, S.S.3
Andrews, K.G.4
Foreman, K.J.5
-
4
-
-
77955027421
-
Estimating the global clinical burden of Plasmodium falciparum malaria in 2007
-
Hay SI, Okiro EA, Gething PW, Patil AP, Tatem AJ, et al. (2010) Estimating the global clinical burden of Plasmodium falciparum malaria in 2007. PLoS Med 7: e1000290.
-
(2010)
PLoS Med
, vol.7
-
-
Hay, S.I.1
Okiro, E.A.2
Gething, P.W.3
Patil, A.P.4
Tatem, A.J.5
-
6
-
-
68049123592
-
Artemisinin resistance in Plasmodium falciparum malaria
-
Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, et al. (2009) Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 361: 455-467.
-
(2009)
N Engl J Med
, vol.361
, pp. 455-467
-
-
Dondorp, A.M.1
Nosten, F.2
Yi, P.3
Das, D.4
Phyo, A.P.5
-
7
-
-
57749099137
-
Evidence of artemisinin-resistant malaria in western Cambodia
-
Noedl H, Se Y, Schaecher K, Smith BL, Socheat D, et al. (2008) Evidence of artemisinin-resistant malaria in western Cambodia. N Engl J Med 359: 2619-2620.
-
(2008)
N Engl J Med
, vol.359
, pp. 2619-2620
-
-
Noedl, H.1
Se, Y.2
Schaecher, K.3
Smith, B.L.4
Socheat, D.5
-
8
-
-
77954324867
-
Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009
-
Thanh NV, Toan TQ, Cowman AF, Casey GJ, Phuc BQ, et al. (2010) Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009. Malar J 9: 181.
-
(2010)
Malar J
, vol.9
, pp. 181
-
-
Thanh, N.V.1
Toan, T.Q.2
Cowman, A.F.3
Casey, G.J.4
Phuc, B.Q.5
-
9
-
-
58649122842
-
Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia
-
Rogers WO, Sem R, Tero T, Chim P, Lim P, et al. (2009) Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia. Malar J 8: 10.
-
(2009)
Malar J
, vol.8
, pp. 10
-
-
Rogers, W.O.1
Sem, R.2
Tero, T.3
Chim, P.4
Lim, P.5
-
10
-
-
84861461519
-
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study
-
doi:10.1016/S0140-6736(12)60484-X
-
Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, et al. (2012) Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet doi:10.1016/S0140-6736(12)60484-X.
-
(2012)
Lancet
-
-
Phyo, A.P.1
Nkhoma, S.2
Stepniewska, K.3
Ashley, E.A.4
Nair, S.5
-
11
-
-
0033636607
-
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance
-
Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, et al. (2000) Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Molecular Cell 6: 861-871.
-
(2000)
Molecular Cell
, vol.6
, pp. 861-871
-
-
Fidock, D.A.1
Nomura, T.2
Talley, A.K.3
Cooper, R.A.4
Dzekunov, S.M.5
-
12
-
-
0000854414
-
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum
-
Cowman AF, Morry MJ, Biggs BA, Cross GA, Foote SJ, (1988) Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America 85: 9109-9113.
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, pp. 9109-9113
-
-
Cowman, A.F.1
Morry, M.J.2
Biggs, B.A.3
Cross, G.A.4
Foote, S.J.5
-
14
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
-
Wilson C, Serrano A, Wasley A, Bogenschutz M, Shankar A, et al. (1989) Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244: 1184-1186.
-
(1989)
Science
, vol.244
, pp. 1184-1186
-
-
Wilson, C.1
Serrano, A.2
Wasley, A.3
Bogenschutz, M.4
Shankar, A.5
-
15
-
-
0028014644
-
Selection of mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 and cross-resistance to halofantrine and quinine
-
Cowman AF, Galatis D, Thompson JK, (1994) Selection of mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 and cross-resistance to halofantrine and quinine. Proceedings of the National Academy of Sciences 91: 1143-1147.
-
(1994)
Proceedings of the National Academy of Sciences
, vol.91
, pp. 1143-1147
-
-
Cowman, A.F.1
Galatis, D.2
Thompson, J.K.3
-
16
-
-
0029916863
-
Frequency of drug resistance in Plasmodium falciparum: a nonsynergistic combination of 5-fluoroorotate and atovaquone suppresses in vitro resistance
-
Gassis S, Rathod P, (1996) Frequency of drug resistance in Plasmodium falciparum: a nonsynergistic combination of 5-fluoroorotate and atovaquone suppresses in vitro resistance. Antimicrob Agents Chemother 40: 914-919.
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 914-919
-
-
Gassis, S.1
Rathod, P.2
-
18
-
-
0031589733
-
Complex Polymorphisms in an ∼330 kDa Protein Are Linked to Chloroquine-Resistant P. falciparum in Southeast Asia and Africa
-
Su X-z, Kirkman LA, Fujioka H, Wellems TE, (1997) Complex Polymorphisms in an ∼330 kDa Protein Are Linked to Chloroquine-Resistant P. falciparum in Southeast Asia and Africa. Cell 91: 593-603.
-
(1997)
Cell
, vol.91
, pp. 593-603
-
-
Su, X.-z.1
Kirkman, L.A.2
Fujioka, H.3
Wellems, T.E.4
-
19
-
-
20244388655
-
Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum
-
Eastman RT, White J, Hucke O, Bauer K, Yokoyama K, et al. (2005) Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum. J Biol Chem 280: 13554-13559.
-
(2005)
J Biol Chem
, vol.280
, pp. 13554-13559
-
-
Eastman, R.T.1
White, J.2
Hucke, O.3
Bauer, K.4
Yokoyama, K.5
-
20
-
-
4143139772
-
Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport
-
Singh A, Rosenthal PJ, (2004) Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport. J Biol Chem 279: 35236-35241.
-
(2004)
J Biol Chem
, vol.279
, pp. 35236-35241
-
-
Singh, A.1
Rosenthal, P.J.2
-
21
-
-
62549103382
-
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum
-
Dharia N, Sidhu A, Cassera M, Westenberger S, Bopp S, et al. (2009) Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum. Genome Biology 10: R21.
-
(2009)
Genome Biology
, vol.10
-
-
Dharia, N.1
Sidhu, A.2
Cassera, M.3
Westenberger, S.4
Bopp, S.5
-
22
-
-
77956280420
-
Spiroindolones, a potent compound class for the treatment of malaria
-
Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, et al. (2010) Spiroindolones, a potent compound class for the treatment of malaria. Science 329: 1175-1180.
-
(2010)
Science
, vol.329
, pp. 1175-1180
-
-
Rottmann, M.1
McNamara, C.2
Yeung, B.K.3
Lee, M.C.4
Zou, B.5
-
23
-
-
79960306786
-
Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites
-
Eastman RT, Dharia NV, Winzeler EA, Fidock DA, (2011) Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites. Antimicrob Agents Chemother 55: 3908-3916.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 3908-3916
-
-
Eastman, R.T.1
Dharia, N.V.2
Winzeler, E.A.3
Fidock, D.A.4
-
24
-
-
84867087846
-
Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum
-
Cui L, Wang Z, Miao J, Miao M, Chandra R, et al. (2012) Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum. Mol Microbiol 86: 111-128.
-
(2012)
Mol Microbiol
, vol.86
, pp. 111-128
-
-
Cui, L.1
Wang, Z.2
Miao, J.3
Miao, M.4
Chandra, R.5
-
25
-
-
57149109574
-
A Genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates
-
Ganesan K, Ponmee N, Jiang L, Fowble JW, White J, et al. (2008) A Genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates. PLoS Pathog 4: e1000214.
-
(2008)
PLoS Pathog
, vol.4
-
-
Ganesan, K.1
Ponmee, N.2
Jiang, L.3
Fowble, J.W.4
White, J.5
-
26
-
-
33846197423
-
Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase
-
Eastman RT, White J, Hucke O, Yokoyama K, Verlinde CL, et al. (2007) Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. Mol Biochem Parasitol 152: 66-71.
-
(2007)
Mol Biochem Parasitol
, vol.152
, pp. 66-71
-
-
Eastman, R.T.1
White, J.2
Hucke, O.3
Yokoyama, K.4
Verlinde, C.L.5
-
27
-
-
84878519336
-
Target gene duplication in ARMD plasmodium falciparum acquiring drug resistance
-
September 13-17 ed
-
Freeman DL, Ponmee N, Guler JL, White J, Gujjar R, et al. (2009) Target gene duplication in ARMD plasmodium falciparum acquiring drug resistance. Woods Hole Molecular Parasitology Meeting XX. September 13-17 ed.
-
(2009)
Woods Hole Molecular Parasitology Meeting XX
-
-
Freeman, D.L.1
Ponmee, N.2
Guler, J.L.3
White, J.4
Gujjar, R.5
-
28
-
-
79952162829
-
Validation of isoleucine utilization targets in Plasmodium falciparum
-
Istvan ES, Dharia NV, Bopp SE, Gluzman I, Winzeler EA, et al. (2011) Validation of isoleucine utilization targets in Plasmodium falciparum. Proc Natl Acad Sci U S A 108: 1627-1632.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1627-1632
-
-
Istvan, E.S.1
Dharia, N.V.2
Bopp, S.E.3
Gluzman, I.4
Winzeler, E.A.5
-
29
-
-
45749119578
-
Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum
-
Phillips MA, Gujjar R, Malmquist NA, White J, El Mazouni F, et al. (2008) Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum. Journal of Medicinal Chemistry 51: 3649-3653.
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, pp. 3649-3653
-
-
Phillips, M.A.1
Gujjar, R.2
Malmquist, N.A.3
White, J.4
El Mazouni, F.5
-
30
-
-
58149178569
-
PlasmoDB: a functional genomic database for malaria parasites
-
Aurrecoechea C, Brestelli J, Brunk BP, Dommer J, Fischer S, et al. (2009) PlasmoDB: a functional genomic database for malaria parasites. Nucleic Acids Res 37: D539-543.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Aurrecoechea, C.1
Brestelli, J.2
Brunk, B.P.3
Dommer, J.4
Fischer, S.5
-
31
-
-
0032167569
-
Distinct frequency-distributions of homopolymeric DNA tracts in different genomes
-
Dechering KJ, Cuelenaere K, Konings RN, Leunissen JA, (1998) Distinct frequency-distributions of homopolymeric DNA tracts in different genomes. Nucleic Acids Res 26: 4056-4062.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 4056-4062
-
-
Dechering, K.J.1
Cuelenaere, K.2
Konings, R.N.3
Leunissen, J.A.4
-
32
-
-
0026048108
-
Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events
-
Triglia T, Foote SJ, Kemp DJ, Cowman AF, (1991) Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events. Mol Cell Biol 11: 5244-5250.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5244-5250
-
-
Triglia, T.1
Foote, S.J.2
Kemp, D.J.3
Cowman, A.F.4
-
33
-
-
33846833887
-
Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites
-
Nair S, Nash D, Sudimack D, Jaidee A, Barends M, et al. (2007) Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites. Mol Biol Evol 24: 562-573.
-
(2007)
Mol Biol Evol
, vol.24
, pp. 562-573
-
-
Nair, S.1
Nash, D.2
Sudimack, D.3
Jaidee, A.4
Barends, M.5
-
34
-
-
0026645269
-
Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
-
Barnes DA, Foote SJ, Galatis D, Kemp DJ, Cowman AF, (1992) Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO J 11: 3067-3075.
-
(1992)
EMBO J
, vol.11
, pp. 3067-3075
-
-
Barnes, D.A.1
Foote, S.J.2
Galatis, D.3
Kemp, D.J.4
Cowman, A.F.5
-
35
-
-
0034922502
-
Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine
-
Thaithong S, Ranford-Cartwright LC, Siripoon N, Harnyuttanakorn P, Kanchanakhan NS, et al. (2001) Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine. Experimental Parasitology 98: 59-70.
-
(2001)
Experimental Parasitology
, vol.98
, pp. 59-70
-
-
Thaithong, S.1
Ranford-Cartwright, L.C.2
Siripoon, N.3
Harnyuttanakorn, P.4
Kanchanakhan, N.S.5
-
36
-
-
0032491390
-
Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon
-
Andersson DI, Slechta ES, Roth JR, (1998) Evidence that gene amplification underlies adaptive mutability of the bacterial lac operon. Science 282: 1133-1135.
-
(1998)
Science
, vol.282
, pp. 1133-1135
-
-
Andersson, D.I.1
Slechta, E.S.2
Roth, J.R.3
-
37
-
-
65649106581
-
Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness
-
Preechapornkul P, Imwong M, Chotivanich K, Pongtavornpinyo W, Dondorp AM, et al. (2009) Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness. Antimicrob Agents Chemother 53: 1509-1515.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1509-1515
-
-
Preechapornkul, P.1
Imwong, M.2
Chotivanich, K.3
Pongtavornpinyo, W.4
Dondorp, A.M.5
-
38
-
-
55449133690
-
Adaptive copy number evolution in malaria parasites
-
Nair S, Miller B, Barends M, Jaidee A, Patel J, et al. (2008) Adaptive copy number evolution in malaria parasites. PLoS Genet 4: e1000243.
-
(2008)
PLoS Genet
, vol.4
-
-
Nair, S.1
Miller, B.2
Barends, M.3
Jaidee, A.4
Patel, J.5
-
39
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
Gardner MJ, Hall N, Fung E, White O, Berriman M, et al. (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419: 498-511.
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
White, O.4
Berriman, M.5
-
40
-
-
40049109886
-
Vivax malaria: neglected and not benign
-
Price RN, Tjitra E, Guerra CA, Yeung S, White NJ, et al. (2007) Vivax malaria: neglected and not benign. Am J Trop Med Hyg 77: 79-87.
-
(2007)
Am J Trop Med Hyg
, vol.77
, pp. 79-87
-
-
Price, R.N.1
Tjitra, E.2
Guerra, C.A.3
Yeung, S.4
White, N.J.5
-
41
-
-
53649104458
-
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
-
Carlton JM, Adams JH, Silva JC, Bidwell SL, Lorenzi H, et al. (2008) Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature 455: 757-763.
-
(2008)
Nature
, vol.455
, pp. 757-763
-
-
Carlton, J.M.1
Adams, J.H.2
Silva, J.C.3
Bidwell, S.L.4
Lorenzi, H.5
-
42
-
-
22244437571
-
The genome of the kinetoplastid parasite, Leishmania major
-
Ivens AC, Peacock CS, Worthey EA, Murphy L, Aggarwal G, et al. (2005) The genome of the kinetoplastid parasite, Leishmania major. Science 309: 436-442.
-
(2005)
Science
, vol.309
, pp. 436-442
-
-
Ivens, A.C.1
Peacock, C.S.2
Worthey, E.A.3
Murphy, L.4
Aggarwal, G.5
-
43
-
-
0026072572
-
Gene amplification in Leishmania
-
Beverley SM, (1991) Gene amplification in Leishmania. Annu Rev Microbiol 45: 417-444.
-
(1991)
Annu Rev Microbiol
, vol.45
, pp. 417-444
-
-
Beverley, S.M.1
-
44
-
-
0022477409
-
DNA bending at adenine. thymine tracts
-
Koo HS, Wu HM, Crothers DM, (1986) DNA bending at adenine. thymine tracts. Nature 320: 501-506.
-
(1986)
Nature
, vol.320
, pp. 501-506
-
-
Koo, H.S.1
Wu, H.M.2
Crothers, D.M.3
-
45
-
-
39149094942
-
DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences
-
Hile SE, Eckert KA, (2008) DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. Nucleic Acids Res 36: 688-696.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 688-696
-
-
Hile, S.E.1
Eckert, K.A.2
-
46
-
-
0025924380
-
A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae
-
Schultes NP, Szostak JW, (1991) A poly(dA.dT) tract is a component of the recombination initiation site at the ARG4 locus in Saccharomyces cerevisiae. Mol Cell Biol 11: 322-328.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 322-328
-
-
Schultes, N.P.1
Szostak, J.W.2
-
47
-
-
0036723660
-
Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences
-
Ira G, Haber JE, (2002) Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol 22: 6384-6392.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6384-6392
-
-
Ira, G.1
Haber, J.E.2
-
48
-
-
0035902443
-
Instability of repetitive DNA sequences: the role of replication in multiple mechanisms
-
Bzymek M, Lovett ST, (2001) Instability of repetitive DNA sequences: the role of replication in multiple mechanisms. Proc Natl Acad Sci U S A 98: 8319-8325.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8319-8325
-
-
Bzymek, M.1
Lovett, S.T.2
-
49
-
-
67651098662
-
Mechanisms of change in gene copy number
-
Hastings PJ, Lupski JR, Rosenberg SM, Ira G, (2009) Mechanisms of change in gene copy number. Nat Rev Genet 10: 551-564.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 551-564
-
-
Hastings, P.J.1
Lupski, J.R.2
Rosenberg, S.M.3
Ira, G.4
-
50
-
-
33646490411
-
On the mechanism of gene amplification induced under stress in Escherichia coli
-
Slack A, Thornton PC, Magner DB, Rosenberg SM, Hastings PJ, (2006) On the mechanism of gene amplification induced under stress in Escherichia coli. PLoS Genet 2: e48.
-
(2006)
PLoS Genet
, vol.2
-
-
Slack, A.1
Thornton, P.C.2
Magner, D.B.3
Rosenberg, S.M.4
Hastings, P.J.5
-
51
-
-
37349109667
-
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
-
Lee JA, Carvalho CM, Lupski JR, (2007) A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell 131: 1235-1247.
-
(2007)
Cell
, vol.131
, pp. 1235-1247
-
-
Lee, J.A.1
Carvalho, C.M.2
Lupski, J.R.3
-
52
-
-
52949143512
-
Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms
-
Payen C, Koszul R, Dujon B, Fischer G, (2008) Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms. PLoS Genet 4: e1000175.
-
(2008)
PLoS Genet
, vol.4
-
-
Payen, C.1
Koszul, R.2
Dujon, B.3
Fischer, G.4
-
53
-
-
79951770203
-
Comparative genomic analysis of simple sequence repeats in three Plasmodium species
-
Tyagi S, Sharma M, Das A, (2011) Comparative genomic analysis of simple sequence repeats in three Plasmodium species. Parasitol Res 108: 451-458.
-
(2011)
Parasitol Res
, vol.108
, pp. 451-458
-
-
Tyagi, S.1
Sharma, M.2
Das, A.3
-
54
-
-
0036193882
-
Crossing over between regions of limited homology in Escherichia coli. RecA-dependent and RecA-independent pathways
-
Lovett ST, Hurley RL, Sutera VA Jr, Aubuchon RH, Lebedeva MA, (2002) Crossing over between regions of limited homology in Escherichia coli. RecA-dependent and RecA-independent pathways. Genetics 160: 851-859.
-
(2002)
Genetics
, vol.160
, pp. 851-859
-
-
Lovett, S.T.1
Hurley, R.L.2
Sutera Jr., V.A.3
Aubuchon, R.H.4
Lebedeva, M.A.5
-
55
-
-
70350385202
-
Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds
-
Deng X, Gujjar R, El Mazouni F, Kaminsky W, Malmquist NA, et al. (2009) Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. Journal of Biological Chemistry 284: 26999-27009.
-
(2009)
Journal of Biological Chemistry
, vol.284
, pp. 26999-27009
-
-
Deng, X.1
Gujjar, R.2
El Mazouni, F.3
Kaminsky, W.4
Malmquist, N.A.5
-
56
-
-
33745726540
-
A systematic map of genetic variation in Plasmodium falciparum
-
Kidgell C, Volkman SK, Daily J, Borevitz JO, Plouffe D, et al. (2006) A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog 2: e57.
-
(2006)
PLoS Pathog
, vol.2
-
-
Kidgell, C.1
Volkman, S.K.2
Daily, J.3
Borevitz, J.O.4
Plouffe, D.5
-
57
-
-
79956220163
-
Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women
-
Sander AF, Salanti A, Lavstsen T, Nielsen MA, Theander TG, et al. Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women. J Infect Dis 203: 1679-1685.
-
J Infect Dis
, vol.203
, pp. 1679-1685
-
-
Sander, A.F.1
Salanti, A.2
Lavstsen, T.3
Nielsen, M.A.4
Theander, T.G.5
-
58
-
-
84857001674
-
False-negative rapid diagnostic tests for malaria and deletion of the histidine-rich repeat region of the hrp2 gene
-
Koita OA, Doumbo OK, Ouattara A, Tall LK, Konare A, et al. (2012) False-negative rapid diagnostic tests for malaria and deletion of the histidine-rich repeat region of the hrp2 gene. Am J Trop Med Hyg 86: 194-198.
-
(2012)
Am J Trop Med Hyg
, vol.86
, pp. 194-198
-
-
Koita, O.A.1
Doumbo, O.K.2
Ouattara, A.3
Tall, L.K.4
Konare, A.5
-
59
-
-
0017317663
-
Culture of human malaria parasites Plasmodium falciparum
-
Haynes JD, Diggs CL, Hines FA, Desjardins RE, (1976) Culture of human malaria parasites Plasmodium falciparum. Nature 263: 767-769.
-
(1976)
Nature
, vol.263
, pp. 767-769
-
-
Haynes, J.D.1
Diggs, C.L.2
Hines, F.A.3
Desjardins, R.E.4
-
60
-
-
0017311840
-
Human malaria parasites in continuous culture
-
Trager W, Jensen JB, (1976) Human malaria parasites in continuous culture. Science 193: 673-675.
-
(1976)
Science
, vol.193
, pp. 673-675
-
-
Trager, W.1
Jensen, J.B.2
-
61
-
-
0026510588
-
Molecular targets of 5-fluoroorotate in the human malaria parasite, Plasmodium falciparum
-
Rathod PK, Leffers NP, Young RD, (1992) Molecular targets of 5-fluoroorotate in the human malaria parasite, Plasmodium falciparum. Antimicrob Agents Chemother 36: 704-711.
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 704-711
-
-
Rathod, P.K.1
Leffers, N.P.2
Young, R.D.3
-
62
-
-
36849034573
-
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
-
Hu G, Llinas M, Li J, Preiser P, Bozdech Z, (2007) Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy. BMC Bioinformatics 8: 350.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 350
-
-
Hu, G.1
Llinas, M.2
Li, J.3
Preiser, P.4
Bozdech, Z.5
-
63
-
-
54749157466
-
Regulatory hotspots in the malaria parasite genome dictate transcriptional variation
-
Gonzales JM, Patel JJ, Ponmee N, Jiang L, Tan A, et al. (2008) Regulatory hotspots in the malaria parasite genome dictate transcriptional variation. PLoS Biol 6: e238.
-
(2008)
PLoS Biol
, vol.6
-
-
Gonzales, J.M.1
Patel, J.J.2
Ponmee, N.3
Jiang, L.4
Tan, A.5
-
64
-
-
4243071596
-
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
-
Bozdech Z, Llinas M, Pulliam BL, Wong ED, Zhu J, et al. (2003) The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol 1: e5.
-
(2003)
PLoS Biol
, vol.1
-
-
Bozdech, Z.1
Llinas, M.2
Pulliam, B.L.3
Wong, E.D.4
Zhu, J.5
-
65
-
-
67349266986
-
Optimizing comparative genomic hybridization probes for genotyping and SNP detection in Plasmodium falciparum
-
Tan JC, Patel JJ, Tan A, Blain JC, Albert TJ, et al. (2009) Optimizing comparative genomic hybridization probes for genotyping and SNP detection in Plasmodium falciparum. Genomics 93: 543-550.
-
(2009)
Genomics
, vol.93
, pp. 543-550
-
-
Tan, J.C.1
Patel, J.J.2
Tan, A.3
Blain, J.C.4
Albert, T.J.5
-
66
-
-
80053176248
-
The landscape of inherited and de novo copy number variants in a Plasmodium falciparum genetic cross
-
Samarakoon U, Gonzales JM, Patel JJ, Tan A, Checkley L, et al. (2011) The landscape of inherited and de novo copy number variants in a Plasmodium falciparum genetic cross. BMC Genomics 12: 457.
-
(2011)
BMC Genomics
, vol.12
, pp. 457
-
-
Samarakoon, U.1
Gonzales, J.M.2
Patel, J.J.3
Tan, A.4
Checkley, L.5
-
67
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW, (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucl Acids Res 29: e45.
-
(2001)
Nucl Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
68
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
Langmead B, Trapnell C, Pop M, Salzberg SL, (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
-
(2009)
Genome Biol
, vol.10
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
69
-
-
0024523842
-
Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro
-
Biggs BA, Kemp DJ, Brown GV, (1989) Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro. Proc Natl Acad Sci U S A 86: 2428-2432.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 2428-2432
-
-
Biggs, B.A.1
Kemp, D.J.2
Brown, G.V.3
-
70
-
-
0026958764
-
A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence
-
Kemp DJ, Thompson J, Barnes DA, Triglia T, Karamalis F, et al. (1992) A chromosome 9 deletion in Plasmodium falciparum results in loss of cytoadherence. Mem Inst Oswaldo Cruz 87 Suppl 3: 85-89.
-
(1992)
Mem Inst Oswaldo Cruz
, vol.87
, Issue.SUPPL.
, pp. 85-89
-
-
Kemp, D.J.1
Thompson, J.2
Barnes, D.A.3
Triglia, T.4
Karamalis, F.5
-
72
-
-
0034019568
-
Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against Plasmodium falciparum
-
Jiang L, Lee P-C, White J, Rathod PK, (2000) Potent and selective activity of a combination of thymidine and 1843U89, a folate-based thymidylate synthase inhibitor, against Plasmodium falciparum. Antimicrob Agents Chemother 44: 1047-1050.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1047-1050
-
-
Jiang, L.1
Lee, P.-C.2
White, J.3
Rathod, P.K.4
-
73
-
-
0027938171
-
Selection and characterization of 5-fluoroorotate-resistant Plasmodium falciparum
-
Rathod PK, Khosla M, Gassis S, Young RD, Lutz C, (1994) Selection and characterization of 5-fluoroorotate-resistant Plasmodium falciparum. Antimicrob Agents Chemother 38: 2871-2876.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 2871-2876
-
-
Rathod, P.K.1
Khosla, M.2
Gassis, S.3
Young, R.D.4
Lutz, C.5
-
74
-
-
0027233039
-
Clonal viability measurements on Plasmodium falciparum to assess in vitro schizonticidal activity of leupeptin, chloroquine, and 5-fluoroorotate
-
Young RD, Rathod PK, (1993) Clonal viability measurements on Plasmodium falciparum to assess in vitro schizonticidal activity of leupeptin, chloroquine, and 5-fluoroorotate. Antimicrob Agents Chemother 37: 1102-1107.
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 1102-1107
-
-
Young, R.D.1
Rathod, P.K.2
-
75
-
-
70350616263
-
Discovery, mechanisms of action and combination therapy of artemisinin
-
Cui L, Su XZ, (2009) Discovery, mechanisms of action and combination therapy of artemisinin. Expert Rev Anti Infect Ther 7: 999-1013.
-
(2009)
Expert Rev Anti Infect Ther
, vol.7
, pp. 999-1013
-
-
Cui, L.1
Su, X.Z.2
|