-
2
-
-
33750047495
-
Management of sepsis
-
Russell JA, (2006) Management of sepsis. N Engl J Med 355: 1699-1713.
-
(2006)
N Engl J Med
, vol.355
, pp. 1699-1713
-
-
Russell, J.A.1
-
3
-
-
0030898553
-
Sepsis and serum cytokine concentrations
-
Damas P, Canivet JL, de Groote D, Vrindts Y, Albert A, et al. (1997) Sepsis and serum cytokine concentrations. Crit Care Med 25: 405-412.
-
(1997)
Crit Care Med
, vol.25
, pp. 405-412
-
-
Damas, P.1
Canivet, J.L.2
de Groote, D.3
Vrindts, Y.4
Albert, A.5
-
4
-
-
11244316320
-
Inhibition of C5 or absence of C6 protects from sepsis mortality
-
Buras JA, Rice L, Orlow D, Pavlides S, Reenstra WR, et al. (2004) Inhibition of C5 or absence of C6 protects from sepsis mortality. Immunobiology 209: 629-635.
-
(2004)
Immunobiology
, vol.209
, pp. 629-635
-
-
Buras, J.A.1
Rice, L.2
Orlow, D.3
Pavlides, S.4
Reenstra, W.R.5
-
5
-
-
43249098418
-
Functional roles for C5a receptors in sepsis
-
Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, et al. (2008) Functional roles for C5a receptors in sepsis. Nat Med 14: 551-557.
-
(2008)
Nat Med
, vol.14
, pp. 551-557
-
-
Rittirsch, D.1
Flierl, M.A.2
Nadeau, B.A.3
Day, D.E.4
Huber-Lang, M.5
-
6
-
-
1142310879
-
The dark side of C5a in sepsis
-
Ward PA, (2004) The dark side of C5a in sepsis. Nat Rev Immunol 4: 133-142.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 133-142
-
-
Ward, P.A.1
-
7
-
-
23044477087
-
Leukocyte apoptosis and its significance in sepsis and shock
-
Wesche DE, Lomas-Neira JL, Perl M, Chung CS, Ayala A, (2005) Leukocyte apoptosis and its significance in sepsis and shock. J Leukoc Biol 78: 325-337.
-
(2005)
J Leukoc Biol
, vol.78
, pp. 325-337
-
-
Wesche, D.E.1
Lomas-Neira, J.L.2
Perl, M.3
Chung, C.S.4
Ayala, A.5
-
8
-
-
70349437186
-
Complement regulators and inhibitory proteins
-
Zipfel PF, Skerka C, (2009) Complement regulators and inhibitory proteins. Nature reviews Immunology 9: 729-740.
-
(2009)
Nature Reviews Immunology
, vol.9
, pp. 729-740
-
-
Zipfel, P.F.1
Skerka, C.2
-
9
-
-
33746294701
-
The role of complement, C5a and its receptors in sepsis and multiorgan dysfunction syndrome
-
Flierl MA, Schreiber H, Huber-Lang MS, (2006) The role of complement, C5a and its receptors in sepsis and multiorgan dysfunction syndrome. J Invest Surg 19: 255-265.
-
(2006)
J Invest Surg
, vol.19
, pp. 255-265
-
-
Flierl, M.A.1
Schreiber, H.2
Huber-Lang, M.S.3
-
10
-
-
79951672227
-
What is new with Nods?
-
Magalhaes JG, Sorbara MT, Girardin SE, Philpott DJ, (2011) What is new with Nods? Curr Opin Immunol 23: 29-34.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 29-34
-
-
Magalhaes, J.G.1
Sorbara, M.T.2
Girardin, S.E.3
Philpott, D.J.4
-
11
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, et al. (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278: 5509-5512.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
-
12
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
Miceli-Richard C, Lesage S, Rybojad M, Prieur AM, Manouvrier-Hanu S, et al. (2001) CARD15 mutations in Blau syndrome. Nat Genet 29: 19-20.
-
(2001)
Nat Genet
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
Lesage, S.2
Rybojad, M.3
Prieur, A.M.4
Manouvrier-Hanu, S.5
-
13
-
-
19944431022
-
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome
-
Kanazawa N, Okafuji I, Kambe N, Nishikomori R, Nakata-Hizume M, et al. (2005) Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. Blood 105: 1195-1197.
-
(2005)
Blood
, vol.105
, pp. 1195-1197
-
-
Kanazawa, N.1
Okafuji, I.2
Kambe, N.3
Nishikomori, R.4
Nakata-Hizume, M.5
-
14
-
-
3242771408
-
Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation
-
Holler E, Rogler G, Herfarth H, Brenmoehl J, Wild PJ, et al. (2004) Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation. Blood 104: 889-894.
-
(2004)
Blood
, vol.104
, pp. 889-894
-
-
Holler, E.1
Rogler, G.2
Herfarth, H.3
Brenmoehl, J.4
Wild, P.J.5
-
15
-
-
80052352663
-
Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice
-
Davis KM, Nakamura S, Weiser JN, (2011) Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. J Clin Invest 121: 3666-3676.
-
(2011)
J Clin Invest
, vol.121
, pp. 3666-3676
-
-
Davis, K.M.1
Nakamura, S.2
Weiser, J.N.3
-
16
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, et al. (2010) Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11: 55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
-
17
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
-
Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C, (2010) ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology 139: 1630-1641, 1641 e1631-1632.
-
(2010)
Gastroenterology
, vol.139
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
Achkar, J.P.4
McDonald, C.5
-
18
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, et al. (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307: 731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
-
19
-
-
84858234491
-
Importance of NOD2/CARD15 gene variants for susceptibility to and outcome of sepsis in Turkish children
-
Tekin D, Dalgic N, Kayaalti Z, Soylemezoglu T, Diler B, et al. (2012) Importance of NOD2/CARD15 gene variants for susceptibility to and outcome of sepsis in Turkish children. Pediatr Crit Care Med 13: e73-77.
-
(2012)
Pediatr Crit Care Med
, vol.13
-
-
Tekin, D.1
Dalgic, N.2
Kayaalti, Z.3
Soylemezoglu, T.4
Diler, B.5
-
20
-
-
34347400796
-
Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo
-
Zhang X, Kimura Y, Fang C, Zhou L, Sfyroera G, et al. (2007) Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood 110: 228-236.
-
(2007)
Blood
, vol.110
, pp. 228-236
-
-
Zhang, X.1
Kimura, Y.2
Fang, C.3
Zhou, L.4
Sfyroera, G.5
-
21
-
-
80052580369
-
Nod2 is essential for temporal development of intestinal microbial communities
-
Rehman A, Sina C, Gavrilova O, Hasler R, Ott S, et al. (2011) Nod2 is essential for temporal development of intestinal microbial communities. Gut 60: 1354-1362.
-
(2011)
Gut
, vol.60
, pp. 1354-1362
-
-
Rehman, A.1
Sina, C.2
Gavrilova, O.3
Hasler, R.4
Ott, S.5
-
22
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, et al. (2011) NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145: 745-757.
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
-
23
-
-
79960667656
-
Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages
-
Hedl M, Abraham C, (2011) Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. J Biol Chem 286: 26440-26449.
-
(2011)
J Biol Chem
, vol.286
, pp. 26440-26449
-
-
Hedl, M.1
Abraham, C.2
-
24
-
-
79952205667
-
Neutrophil IL-10 suppresses peritoneal inflammatory monocytes during polymicrobial sepsis
-
Ocuin LM, Bamboat ZM, Balachandran VP, Cavnar MJ, Obaid H, et al. (2011) Neutrophil IL-10 suppresses peritoneal inflammatory monocytes during polymicrobial sepsis. J Leukoc Biol 89: 423-432.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 423-432
-
-
Ocuin, L.M.1
Bamboat, Z.M.2
Balachandran, V.P.3
Cavnar, M.J.4
Obaid, H.5
-
27
-
-
33846936219
-
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
-
Park JH, Kim YG, McDonald C, Kanneganti TD, Hasegawa M, et al. (2007) RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J Immunol 178: 2380-2386.
-
(2007)
J Immunol
, vol.178
, pp. 2380-2386
-
-
Park, J.H.1
Kim, Y.G.2
McDonald, C.3
Kanneganti, T.D.4
Hasegawa, M.5
-
28
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, et al. (2002) Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 416: 190-194.
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
-
29
-
-
34249826059
-
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
-
Windheim M, Lang C, Peggie M, Plater LA, Cohen P, (2007) Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. The Biochemical journal 404: 179-190.
-
(2007)
The Biochemical Journal
, vol.404
, pp. 179-190
-
-
Windheim, M.1
Lang, C.2
Peggie, M.3
Plater, L.A.4
Cohen, P.5
-
30
-
-
38349081519
-
Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta
-
Ferwerda G, Kramer M, de Jong D, Piccini A, Joosten LA, et al. (2008) Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta. Eur J Immunol 38: 184-191.
-
(2008)
Eur J Immunol
, vol.38
, pp. 184-191
-
-
Ferwerda, G.1
Kramer, M.2
de Jong, D.3
Piccini, A.4
Joosten, L.A.5
-
31
-
-
65249115914
-
A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1
-
Noguchi E, Homma Y, Kang X, Netea MG, Ma X, (2009) A Crohn's disease-associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1. Nat Immunol 10: 471-479.
-
(2009)
Nat Immunol
, vol.10
, pp. 471-479
-
-
Noguchi, E.1
Homma, Y.2
Kang, X.3
Netea, M.G.4
Ma, X.5
-
32
-
-
0026655638
-
Recombinant interleukin-1 receptor antagonist (IL-1ra): effective therapy against gram-negative sepsis in rats
-
discussion 193-184
-
Alexander HR, Doherty GM, Venzon DJ, Merino MJ, Fraker DL, et al. (1992) Recombinant interleukin-1 receptor antagonist (IL-1ra): effective therapy against gram-negative sepsis in rats. Surgery 112: 188-193; discussion 193-184.
-
(1992)
Surgery
, vol.112
, pp. 188-193
-
-
Alexander, H.R.1
Doherty, G.M.2
Venzon, D.J.3
Merino, M.J.4
Fraker, D.L.5
-
33
-
-
0027200968
-
Interleukin-1 receptor antibody (IL-1rab) protection and treatment against lethal endotoxemia in mice
-
McNamara MJ, Norton JA, Nauta RJ, Alexander HR, (1993) Interleukin-1 receptor antibody (IL-1rab) protection and treatment against lethal endotoxemia in mice. J Surg Res 54: 316-321.
-
(1993)
J Surg Res
, vol.54
, pp. 316-321
-
-
McNamara, M.J.1
Norton, J.A.2
Nauta, R.J.3
Alexander, H.R.4
-
34
-
-
0025900825
-
Human recombinant interleukin-1 alpha protection against the lethality of endotoxin and experimental sepsis in mice
-
Alexander HR, Doherty GM, Fraker DL, Block MI, Swedenborg JE, et al. (1991) Human recombinant interleukin-1 alpha protection against the lethality of endotoxin and experimental sepsis in mice. J Surg Res 50: 421-424.
-
(1991)
J Surg Res
, vol.50
, pp. 421-424
-
-
Alexander, H.R.1
Doherty, G.M.2
Fraker, D.L.3
Block, M.I.4
Swedenborg, J.E.5
-
35
-
-
0037180768
-
The immunopathogenesis of sepsis
-
Cohen J, (2002) The immunopathogenesis of sepsis. Nature 420: 885-891.
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
36
-
-
79751504193
-
The pathogenesis of sepsis
-
Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG, (2011) The pathogenesis of sepsis. Annu Rev Pathol 6: 19-48.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 19-48
-
-
Stearns-Kurosawa, D.J.1
Osuchowski, M.F.2
Valentine, C.3
Kurosawa, S.4
Remick, D.G.5
-
37
-
-
0021713655
-
Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes
-
Medof ME, Kinoshita T, Nussenzweig V, (1984) Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes. The Journal of experimental medicine 160: 1558-1578.
-
(1984)
The Journal of Experimental Medicine
, vol.160
, pp. 1558-1578
-
-
Medof, M.E.1
Kinoshita, T.2
Nussenzweig, V.3
-
38
-
-
38449105692
-
Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production
-
Lalli PN, Strainic MG, Lin F, Medof ME, Heeger PS, (2007) Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. Journal of immunology 179: 5793-5802.
-
(2007)
Journal of Immunology
, vol.179
, pp. 5793-5802
-
-
Lalli, P.N.1
Strainic, M.G.2
Lin, F.3
Medof, M.E.4
Heeger, P.S.5
-
39
-
-
34249318067
-
Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis
-
Bozza FA, Salluh JI, Japiassu AM, Soares M, Assis EF, et al. (2007) Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit Care 11: R49.
-
(2007)
Crit Care
, vol.11
-
-
Bozza, F.A.1
Salluh, J.I.2
Japiassu, A.M.3
Soares, M.4
Assis, E.F.5
-
40
-
-
0029975877
-
Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum
-
Kumar A, Thota V, Dee L, Olson J, Uretz E, et al. (1996) Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 183: 949-958.
-
(1996)
J Exp Med
, vol.183
, pp. 949-958
-
-
Kumar, A.1
Thota, V.2
Dee, L.3
Olson, J.4
Uretz, E.5
-
41
-
-
0035820181
-
IL-10 mediation of activation-induced TH1 cell apoptosis and lymphoid dysfunction in polymicrobial sepsis
-
Ayala A, Chung CS, Song GY, Chaudry IH, (2001) IL-10 mediation of activation-induced TH1 cell apoptosis and lymphoid dysfunction in polymicrobial sepsis. Cytokine 14: 37-48.
-
(2001)
Cytokine
, vol.14
, pp. 37-48
-
-
Ayala, A.1
Chung, C.S.2
Song, G.Y.3
Chaudry, I.H.4
-
42
-
-
0036644330
-
Anti-IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: dependence on timing of immunomodulating intervention
-
Kalechman Y, Gafter U, Gal R, Rushkin G, Yan D, et al. (2002) Anti-IL-10 therapeutic strategy using the immunomodulator AS101 in protecting mice from sepsis-induced death: dependence on timing of immunomodulating intervention. J Immunol 169: 384-392.
-
(2002)
J Immunol
, vol.169
, pp. 384-392
-
-
Kalechman, Y.1
Gafter, U.2
Gal, R.3
Rushkin, G.4
Yan, D.5
-
43
-
-
0035115013
-
Alveolar macrophage deactivation in murine septic peritonitis: role of interleukin 10
-
Reddy RC, Chen GH, Newstead MW, Moore T, Zeng X, et al. (2001) Alveolar macrophage deactivation in murine septic peritonitis: role of interleukin 10. Infect Immun 69: 1394-1401.
-
(2001)
Infect Immun
, vol.69
, pp. 1394-1401
-
-
Reddy, R.C.1
Chen, G.H.2
Newstead, M.W.3
Moore, T.4
Zeng, X.5
-
44
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss RS, Nicholson DW, (2006) Apoptosis and caspases regulate death and inflammation in sepsis. Nature reviews Immunology 6: 813-822.
-
(2006)
Nature Reviews Immunology
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
45
-
-
78649890151
-
Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses
-
Tigno-Aranjuez JT, Asara JM, Abbott DW, (2010) Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses. Genes & development 24: 2666-2677.
-
(2010)
Genes & Development
, vol.24
, pp. 2666-2677
-
-
Tigno-Aranjuez, J.T.1
Asara, J.M.2
Abbott, D.W.3
-
46
-
-
84865546561
-
Immunology. Stalling sepsis?
-
Leslie M, (2012) Immunology. Stalling sepsis? Science 337: 1036.
-
(2012)
Science
, vol.337
, pp. 1036
-
-
Leslie, M.1
-
47
-
-
33748296238
-
FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation
-
Kim HY, Kim S, Chung DH, (2006) FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation. J Clin Invest 116: 2484-2492.
-
(2006)
J Clin Invest
, vol.116
, pp. 2484-2492
-
-
Kim, H.Y.1
Kim, S.2
Chung, D.H.3
|