메뉴 건너뛰기




Volumn 334, Issue 1, 2013, Pages 46-55

Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma

Author keywords

Gene mutation; Genotoxicity; Metabolic activation; PCB

Indexed keywords

POLYCHLORINATED BIPHENYL DERIVATIVE; REACTIVE OXYGEN METABOLITE; CARCINOGEN; DNA ADDUCT; PHOSPHORUS; POLYCHLORINATED BIPHENYL;

EID: 84878468220     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.11.041     Document Type: Review
Times cited : (70)

References (116)
  • 1
    • 0029863866 scopus 로고    scopus 로고
    • Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase
    • Amaro A.R., Oakley G.G., Bauer U., Spielmann H.P., Robertson L.W. Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase. Chem. Res. Toxicol. 1996, 9:623-629.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 623-629
    • Amaro, A.R.1    Oakley, G.G.2    Bauer, U.3    Spielmann, H.P.4    Robertson, L.W.5
  • 2
    • 0028122271 scopus 로고
    • International commission for protection against environmental mutagens and carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents
    • Anderson R.D., Berger N.A. International commission for protection against environmental mutagens and carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents. Mutat. Res. 1994, 309:109-142.
    • (1994) Mutat. Res. , vol.309 , pp. 109-142
    • Anderson, R.D.1    Berger, N.A.2
  • 3
    • 0037420968 scopus 로고    scopus 로고
    • Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro
    • Arif J.M., Lehmler H.J., Robertson L.W., Gupta R.C. Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro. Chem. Biol. Interact. 2003, 142:307-316.
    • (2003) Chem. Biol. Interact. , vol.142 , pp. 307-316
    • Arif, J.M.1    Lehmler, H.J.2    Robertson, L.W.3    Gupta, R.C.4
  • 4
    • 0030830108 scopus 로고    scopus 로고
    • Metabolism of 2,4,5,2',4',5'-hexachlorobiphenyl (PCB153) in guinea pig
    • Ariyoshi N., Koga N., Yoshimura H., Oguri K. Metabolism of 2,4,5,2',4',5'-hexachlorobiphenyl (PCB153) in guinea pig. Xenobiotica 1997, 27:973-983.
    • (1997) Xenobiotica , vol.27 , pp. 973-983
    • Ariyoshi, N.1    Koga, N.2    Yoshimura, H.3    Oguri, K.4
  • 5
    • 0027425934 scopus 로고
    • Identification of in vitro metabolites of 2,4,6,2',4',6'-hexachlorobiphenyl from phenobarbital-treated dog liver microsomes
    • Ariyoshi N., Yoshimura H., Oguri K. Identification of in vitro metabolites of 2,4,6,2',4',6'-hexachlorobiphenyl from phenobarbital-treated dog liver microsomes. Biol. Pharm. Bull. 1993, 16:852-857.
    • (1993) Biol. Pharm. Bull. , vol.16 , pp. 852-857
    • Ariyoshi, N.1    Yoshimura, H.2    Oguri, K.3
  • 6
    • 0030018828 scopus 로고    scopus 로고
    • PCBs do not induce DNA breakage in vitro in human lymphocytes
    • Belpaeme K., Delbeke K., Zhu L., Kirsch-Volders M. PCBs do not induce DNA breakage in vitro in human lymphocytes. Mutagenesis 1996, 11:383-389.
    • (1996) Mutagenesis , vol.11 , pp. 383-389
    • Belpaeme, K.1    Delbeke, K.2    Zhu, L.3    Kirsch-Volders, M.4
  • 7
    • 33747466075 scopus 로고    scopus 로고
    • Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate
    • Bender R.P., Lehmler H.J., Robertson L.W., Ludewig G., Osheroff N. Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate. Biochemistry 2006, 45:10140-10152.
    • (2006) Biochemistry , vol.45 , pp. 10140-10152
    • Bender, R.P.1    Lehmler, H.J.2    Robertson, L.W.3    Ludewig, G.4    Osheroff, N.5
  • 8
    • 34447136194 scopus 로고    scopus 로고
    • Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate
    • Bender R.P., Osheroff N. Mutation of cysteine residue 455 to alanine in human topoisomerase IIalpha confers hypersensitivity to quinones: enhancing DNA scission by closing the N-terminal protein gate. Chem. Res. Toxicol. 2007, 20:975-981.
    • (2007) Chem. Res. Toxicol. , vol.20 , pp. 975-981
    • Bender, R.P.1    Osheroff, N.2
  • 9
    • 0344406812 scopus 로고    scopus 로고
    • DNA adducts in cultures of polychlorinated biphenyl-treated human hepatocytes
    • Borlak J., Hock A., Hansen T., Richter E. DNA adducts in cultures of polychlorinated biphenyl-treated human hepatocytes. Toxicol. Appl. Pharmacol. 2003, 188:81-91.
    • (2003) Toxicol. Appl. Pharmacol. , vol.188 , pp. 81-91
    • Borlak, J.1    Hock, A.2    Hansen, T.3    Richter, E.4
  • 11
    • 0024431942 scopus 로고
    • Photo-induced formation of DNA adducts of 2,2',4,4',5,5'-hexachlorobiphenyl in cultured human cells
    • Buff K., Wegenke M., Brundl A. Photo-induced formation of DNA adducts of 2,2',4,4',5,5'-hexachlorobiphenyl in cultured human cells. Biochem. Pharmacol. 1989, 38:2773-2779.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 2773-2779
    • Buff, K.1    Wegenke, M.2    Brundl, A.3
  • 12
    • 0032924696 scopus 로고    scopus 로고
    • Assessment of the genotoxicity of contaminated soil with the allium/vicia-micronucleus and the tradescantia-micronucleus assays
    • Cotelle S., Masfaraud J.F., Ferard J.F. Assessment of the genotoxicity of contaminated soil with the allium/vicia-micronucleus and the tradescantia-micronucleus assays. Mutat. Res. 1999, 426:167-171.
    • (1999) Mutat. Res. , vol.426 , pp. 167-171
    • Cotelle, S.1    Masfaraud, J.F.2    Ferard, J.F.3
  • 13
    • 0018749299 scopus 로고
    • 4-chlorobiphenyl metabolism: the effects of chemical inducers
    • Crawford A., Safe S. 4-chlorobiphenyl metabolism: the effects of chemical inducers. Gen. Pharmacol. 1979, 10:227-231.
    • (1979) Gen. Pharmacol. , vol.10 , pp. 227-231
    • Crawford, A.1    Safe, S.2
  • 14
    • 0021241875 scopus 로고
    • Incorporation of labeled 2,4,5,2',4',5'-hexachlorobiphenyl into the nuclear fraction of rat hepatocytes in vivo
    • Daubeze M., Narbonne J.F. Incorporation of labeled 2,4,5,2',4',5'-hexachlorobiphenyl into the nuclear fraction of rat hepatocytes in vivo. Toxicology 1984, 31:315-318.
    • (1984) Toxicology , vol.31 , pp. 315-318
    • Daubeze, M.1    Narbonne, J.F.2
  • 15
    • 0029941160 scopus 로고    scopus 로고
    • Sensitive detection of 8-hydroxy-2'deoxyguanosine in DNA by 32P-postlabeling assay and the basal levels in rat tissues
    • Devanaboyina U., Gupta R.C. Sensitive detection of 8-hydroxy-2'deoxyguanosine in DNA by 32P-postlabeling assay and the basal levels in rat tissues. Carcinogenesis 1996, 17:917-924.
    • (1996) Carcinogenesis , vol.17 , pp. 917-924
    • Devanaboyina, U.1    Gupta, R.C.2
  • 16
    • 0017710611 scopus 로고
    • Tumor-initiating ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Arochlor 1254 in the two-stage system of mouse skin carcinogenesis
    • DiGiovanni J., Viaje A., Berry D.L., Slaga T.J., Juchau M.R. Tumor-initiating ability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Arochlor 1254 in the two-stage system of mouse skin carcinogenesis. Bull. Environ. Contam. Toxicol. 1977, 18:552-557.
    • (1977) Bull. Environ. Contam. Toxicol. , vol.18 , pp. 552-557
    • DiGiovanni, J.1    Viaje, A.2    Berry, D.L.3    Slaga, T.J.4    Juchau, M.R.5
  • 17
    • 0029970494 scopus 로고    scopus 로고
    • P450 induction by Aroclor 1254 and 3,3',4,4'-tetrachlorobiphenyl in cultured hepatocytes from rat, quail and man: interspecies comparison, comparative biochemistry and physiology. Part C
    • Dubois M., De Waziers I., Thome J.P., Kremers P. P450 induction by Aroclor 1254 and 3,3',4,4'-tetrachlorobiphenyl in cultured hepatocytes from rat, quail and man: interspecies comparison, comparative biochemistry and physiology. Part C. Pharmacol. Toxicol. Endocrinol. 1996, 113:51-59.
    • (1996) Pharmacol. Toxicol. Endocrinol. , vol.113 , pp. 51-59
    • Dubois, M.1    De Waziers, I.2    Thome, J.P.3    Kremers, P.4
  • 18
    • 0029583059 scopus 로고
    • DNA adducts and P450 induction in human, rat and avian liver cells after exposure to polychlorobiphenyls
    • Dubois M., Pfohl-Leszkowicz A., Grosse Y., Kremers P. DNA adducts and P450 induction in human, rat and avian liver cells after exposure to polychlorobiphenyls. Mutat. Res. 1995, 345:181-190.
    • (1995) Mutat. Res. , vol.345 , pp. 181-190
    • Dubois, M.1    Pfohl-Leszkowicz, A.2    Grosse, Y.3    Kremers, P.4
  • 19
    • 80054762464 scopus 로고    scopus 로고
    • Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1
    • Ekuase E.J., Liu Y., Lehmler H.J., Robertson L.W., Duffel M.W. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chem. Res. Toxicol. 2011, 24:1720-1728.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 1720-1728
    • Ekuase, E.J.1    Liu, Y.2    Lehmler, H.J.3    Robertson, L.W.4    Duffel, M.W.5
  • 23
    • 10044241824 scopus 로고    scopus 로고
    • Comparison of different initiation protocols in the resistant hepatocyte model
    • Espandiari P., Robertson L.W., Srinivasan C., Glauert H.P. Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology 2005, 206:373-381.
    • (2005) Toxicology , vol.206 , pp. 373-381
    • Espandiari, P.1    Robertson, L.W.2    Srinivasan, C.3    Glauert, H.P.4
  • 24
    • 34548436087 scopus 로고    scopus 로고
    • Genotoxicity of non-covalent interactions: DNA intercalators
    • Ferguson L.R., Denny W.A. Genotoxicity of non-covalent interactions: DNA intercalators. Mutat. Res. 2007, 623:14-23.
    • (2007) Mutat. Res. , vol.623 , pp. 14-23
    • Ferguson, L.R.1    Denny, W.A.2
  • 25
    • 77957246020 scopus 로고    scopus 로고
    • Polyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationships
    • Flor S., Ludewig G. Polyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationships. Environ. Int. 2010, 36:962-969.
    • (2010) Environ. Int. , vol.36 , pp. 962-969
    • Flor, S.1    Ludewig, G.2
  • 26
    • 0019945045 scopus 로고
    • Identification of an arene oxide metabolite of 2,2',5-5'-tetrachlorobiphenyl by gas chromatography-mass spectroscopy
    • Forgue S.T., Allen J.R. Identification of an arene oxide metabolite of 2,2',5-5'-tetrachlorobiphenyl by gas chromatography-mass spectroscopy. Chem. Biol. Interact. 1982, 40:233-245.
    • (1982) Chem. Biol. Interact. , vol.40 , pp. 233-245
    • Forgue, S.T.1    Allen, J.R.2
  • 27
    • 0028142243 scopus 로고
    • Comparison of DNA adduct levels in human placenta from polychlorinated biphenyl exposed women and smokers in which CYP 1A1 levels are similarly elevated
    • Gallagher J.E., Everson R.B., Lewtas J., George M., Lucier G.W. Comparison of DNA adduct levels in human placenta from polychlorinated biphenyl exposed women and smokers in which CYP 1A1 levels are similarly elevated. Teratog Carcinog. Mutag. 1994, 14:183-192.
    • (1994) Teratog Carcinog. Mutag. , vol.14 , pp. 183-192
    • Gallagher, J.E.1    Everson, R.B.2    Lewtas, J.3    George, M.4    Lucier, G.W.5
  • 29
    • 0022438848 scopus 로고
    • Models of hepatocarcinogenesis in the rat-contrasts and comparisons
    • Goldsworthy T.L., Hanigan M.H., Pitot H.C. Models of hepatocarcinogenesis in the rat-contrasts and comparisons. Crit. Rev. Toxicol. 1986, 17:61-89.
    • (1986) Crit. Rev. Toxicol. , vol.17 , pp. 61-89
    • Goldsworthy, T.L.1    Hanigan, M.H.2    Pitot, H.C.3
  • 30
    • 18044392915 scopus 로고    scopus 로고
    • Telomeres, crisis and cancer
    • Greenberg R.A. Telomeres, crisis and cancer. Curr. Mol. Med. 2005, 5:213-218.
    • (2005) Curr. Mol. Med. , vol.5 , pp. 213-218
    • Greenberg, R.A.1
  • 31
    • 0020334611 scopus 로고
    • 32P-Postlabeling analysis of non-radioactive aromatic carcinogen-DNA adducts
    • Gupta R.C., Reddy M.V., Randerath K. 32P-Postlabeling analysis of non-radioactive aromatic carcinogen-DNA adducts. Carcinogenesis 1982, 3:1081-1092.
    • (1982) Carcinogenesis , vol.3 , pp. 1081-1092
    • Gupta, R.C.1    Reddy, M.V.2    Randerath, K.3
  • 32
    • 0034867530 scopus 로고    scopus 로고
    • An improved (32)P-postlabeling assay for the sensitive detection of 8-oxodeoxyguanosine in tissue DNA
    • Gupta R.C., Arif J.M. An improved (32)P-postlabeling assay for the sensitive detection of 8-oxodeoxyguanosine in tissue DNA. Chem. Res. Toxicol. 2001, 14:951-957.
    • (2001) Chem. Res. Toxicol. , vol.14 , pp. 951-957
    • Gupta, R.C.1    Arif, J.M.2
  • 33
    • 0021893111 scopus 로고
    • Mutagenicity of PCBs and their pyrosynthetic derivatives in cell-mediated assay
    • Hattula M.L. Mutagenicity of PCBs and their pyrosynthetic derivatives in cell-mediated assay. Environ. Health Perspect. 1985, 60:255-257.
    • (1985) Environ. Health Perspect. , vol.60 , pp. 255-257
    • Hattula, M.L.1
  • 34
    • 0021857936 scopus 로고
    • Influence of cell proliferation on initiating activity of pure polychlorinated biphenyls and complex mixtures in resistant hepatocyte in vivo assays for carcinogenicity
    • Hayes M.A., Safe S.H., Armstrong D., Cameron R.G. Influence of cell proliferation on initiating activity of pure polychlorinated biphenyls and complex mixtures in resistant hepatocyte in vivo assays for carcinogenicity. J. Natl. Cancer Inst. 1985, 74:1037-1041.
    • (1985) J. Natl. Cancer Inst. , vol.74 , pp. 1037-1041
    • Hayes, M.A.1    Safe, S.H.2    Armstrong, D.3    Cameron, R.G.4
  • 35
    • 0023062199 scopus 로고
    • Three stage carcinogenesis in mouse skin-recent results and present status of an advanced model system of chemical carcinogenesis
    • Hecker E. Three stage carcinogenesis in mouse skin-recent results and present status of an advanced model system of chemical carcinogenesis. Toxicol. Pathol. 1987, 15:245-258.
    • (1987) Toxicol. Pathol. , vol.15 , pp. 245-258
    • Hecker, E.1
  • 36
    • 0017905131 scopus 로고
    • Activation of [14C] chlorobiphenyls to protein-binding metabolites by rat liver microsomes
    • Hesse S., Mezger M., Wolff T. Activation of [14C] chlorobiphenyls to protein-binding metabolites by rat liver microsomes. Chem. Biol. Interact. 1978, 20:355-365.
    • (1978) Chem. Biol. Interact. , vol.20 , pp. 355-365
    • Hesse, S.1    Mezger, M.2    Wolff, T.3
  • 37
    • 45249092256 scopus 로고    scopus 로고
    • Estrogenic phenol and catechol metabolites of PCBs modulate catechol-O-methyltransferase expression via the estrogen receptor: potential contribution to cancer risk
    • Ho P.W., Garner C.E., Ho J.W., Leung K.C., Chu A.C., Kwok K.H., Kung M.H., Burka L.T., Ramsden D.B., Ho S.L. Estrogenic phenol and catechol metabolites of PCBs modulate catechol-O-methyltransferase expression via the estrogen receptor: potential contribution to cancer risk. Curr. Drug Metab. 2008, 9:304-309.
    • (2008) Curr. Drug Metab. , vol.9 , pp. 304-309
    • Ho, P.W.1    Garner, C.E.2    Ho, J.W.3    Leung, K.C.4    Chu, A.C.5    Kwok, K.H.6    Kung, M.H.7    Burka, L.T.8    Ramsden, D.B.9    Ho, S.L.10
  • 38
    • 84891914257 scopus 로고    scopus 로고
    • IARC, A Review of Human Carcinogens: Chemical Agents and Related Occupations
    • IARC, A Review of Human Carcinogens: Chemical Agents and Related Occupations, 2012.
    • (2012)
  • 39
  • 40
    • 0033958649 scopus 로고    scopus 로고
    • Induction of aberrant mitosis with PCBs: particular efficiency of 2, 3,3',4,4'-pentachlorobiphenyl and synergism with triphenyltin
    • Jensen K.G., Wiberg K., Klasson-Wehler E., Onfelt A. Induction of aberrant mitosis with PCBs: particular efficiency of 2, 3,3',4,4'-pentachlorobiphenyl and synergism with triphenyltin. Mutagenesis 2000, 15:9-15.
    • (2000) Mutagenesis , vol.15 , pp. 9-15
    • Jensen, K.G.1    Wiberg, K.2    Klasson-Wehler, E.3    Onfelt, A.4
  • 42
    • 0025912443 scopus 로고
    • Cytogenetic analysis of peripheral blood lymphocytes in workers occupationally exposed to polychlorinated biphenyls
    • Kalina I., Sram R.J., Konecna H., Ondrussekova A. Cytogenetic analysis of peripheral blood lymphocytes in workers occupationally exposed to polychlorinated biphenyls. Teratog Carcinog. Mutag. 1991, 11:77-82.
    • (1991) Teratog Carcinog. Mutag. , vol.11 , pp. 77-82
    • Kalina, I.1    Sram, R.J.2    Konecna, H.3    Ondrussekova, A.4
  • 43
    • 0019779039 scopus 로고
    • Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P-450
    • Kaminsky L.S., Kennedy M.W., Adams S.M., Guengerich F.P. Metabolism of dichlorobiphenyls by highly purified isozymes of rat liver cytochrome P-450. Biochemistry 1981, 20:7379-7384.
    • (1981) Biochemistry , vol.20 , pp. 7379-7384
    • Kaminsky, L.S.1    Kennedy, M.W.2    Adams, S.M.3    Guengerich, F.P.4
  • 44
    • 79959963304 scopus 로고    scopus 로고
    • Oxidative stress and oxidative damage in chemical carcinogenesis
    • Klaunig J.E., Wang Z., Pu X., Zhou S. Oxidative stress and oxidative damage in chemical carcinogenesis. Toxicol. Appl. Pharmacol. 2011, 254:86-99.
    • (2011) Toxicol. Appl. Pharmacol. , vol.254 , pp. 86-99
    • Klaunig, J.E.1    Wang, Z.2    Pu, X.3    Zhou, S.4
  • 45
    • 33847324861 scopus 로고    scopus 로고
    • 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats
    • Lehmann L., Esch H., Kirby P., Robertson L.W., Ludewig G. 4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats. Carcinogenesis 2007, 28:471-478.
    • (2007) Carcinogenesis , vol.28 , pp. 471-478
    • Lehmann, L.1    Esch, H.2    Kirby, P.3    Robertson, L.W.4    Ludewig, G.5
  • 46
    • 0033845964 scopus 로고    scopus 로고
    • Formation of quinonoid-derived protein adducts in the liver and brain of Sprague-Dawley rats treated with 2,2',5, 5'-tetrachlorobiphenyl
    • Lin P.H., Sangaiah R., Ranasinghe A., Upton P.B., La D.K., Gold A., Swenberg J.A. Formation of quinonoid-derived protein adducts in the liver and brain of Sprague-Dawley rats treated with 2,2',5, 5'-tetrachlorobiphenyl. Chem. Res. Toxicol. 2000, 13:710-718.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 710-718
    • Lin, P.H.1    Sangaiah, R.2    Ranasinghe, A.3    Upton, P.B.4    La, D.K.5    Gold, A.6    Swenberg, J.A.7
  • 47
    • 33845276999 scopus 로고    scopus 로고
    • Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1
    • Liu Y., Apak T.I., Lehmler H.J., Robertson L.W., Duffel M.W. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chem. Res. Toxicol. 2006, 19:1420-1425.
    • (2006) Chem. Res. Toxicol. , vol.19 , pp. 1420-1425
    • Liu, Y.1    Apak, T.I.2    Lehmler, H.J.3    Robertson, L.W.4    Duffel, M.W.5
  • 48
    • 66449092829 scopus 로고    scopus 로고
    • Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status
    • Liu Y., Smart J.T., Song Y., Lehmler H.J., Robertson L.W., Duffel M.W. Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metab. Dispos.: Biol. Fate Chem. 2009, 37:1065-1072.
    • (2009) Drug Metab. Dispos.: Biol. Fate Chem. , vol.37 , pp. 1065-1072
    • Liu, Y.1    Smart, J.T.2    Song, Y.3    Lehmler, H.J.4    Robertson, L.W.5    Duffel, M.W.6
  • 49
    • 0002638819 scopus 로고    scopus 로고
    • The University Press of Kentucky, Lexington, KY, L.W. Robertson, J.C. Hansen (Eds.)
    • Ludewig G. Cancer initiation by PCBs 2001, The University Press of Kentucky, Lexington, KY. L.W. Robertson, J.C. Hansen (Eds.).
    • (2001) Cancer initiation by PCBs
    • Ludewig, G.1
  • 51
    • 79957951669 scopus 로고    scopus 로고
    • Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2)
    • Marabini L., Calo R., Fucile S. Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2). Toxicol. In Vitro 2011, 25:1045-1052.
    • (2011) Toxicol. In Vitro , vol.25 , pp. 1045-1052
    • Marabini, L.1    Calo, R.2    Fucile, S.3
  • 53
    • 0030051958 scopus 로고    scopus 로고
    • Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl
    • McLean M.R., Bauer U., Amaro A.R., Robertson L.W. Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl. Chem. Res. Toxicol. 1996, 9:158-164.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 158-164
    • McLean, M.R.1    Bauer, U.2    Amaro, A.R.3    Robertson, L.W.4
  • 54
    • 0030049843 scopus 로고    scopus 로고
    • Detection of PCB adducts by the 32P-postlabeling technique
    • McLean M.R., Robertson L.W., Gupta R.C. Detection of PCB adducts by the 32P-postlabeling technique. Chem. Res. Toxicol. 1996, 9:165-171.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 165-171
    • McLean, M.R.1    Robertson, L.W.2    Gupta, R.C.3
  • 55
    • 0034656402 scopus 로고    scopus 로고
    • Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)-1, 4-benzoquinones, oxidation products of polychlorinated biphenyls
    • McLean M.R., Twaroski T.P., Robertson L.W. Redox cycling of 2-(x'-mono, -di, -trichlorophenyl)-1, 4-benzoquinones, oxidation products of polychlorinated biphenyls. Arch. Biochem. Biophys. 2000, 376:449-455.
    • (2000) Arch. Biochem. Biophys. , vol.376 , pp. 449-455
    • McLean, M.R.1    Twaroski, T.P.2    Robertson, L.W.3
  • 56
    • 0026670188 scopus 로고
    • Interactive cytogenetic effects on rat bone-marrow due to chronic ingestion of 2,5,2',5' and 3,4,3',4' PCBs
    • Meisner L.F., Roloff B., Sargent L., Pitot H. Interactive cytogenetic effects on rat bone-marrow due to chronic ingestion of 2,5,2',5' and 3,4,3',4' PCBs. Mutat. Res. 1992, 283:179-183.
    • (1992) Mutat. Res. , vol.283 , pp. 179-183
    • Meisner, L.F.1    Roloff, B.2    Sargent, L.3    Pitot, H.4
  • 57
    • 0018682905 scopus 로고
    • In vivo binding of 2,3,6,2',3',6'-hexachlorobiphenyl and 2,4,5,2',4',5'-hexachlorobiphenyl to mouse liver macromolecules
    • Morales N.M., Matthews H.B. In vivo binding of 2,3,6,2',3',6'-hexachlorobiphenyl and 2,4,5,2',4',5'-hexachlorobiphenyl to mouse liver macromolecules. Chem. Biol. Interact. 1979, 27:99-110.
    • (1979) Chem. Biol. Interact. , vol.27 , pp. 99-110
    • Morales, N.M.1    Matthews, H.B.2
  • 58
    • 0032007871 scopus 로고    scopus 로고
    • Toxicopathic hepatic lesions in subadult English sole (Pleuronectes vetulus) from Puget Sound, Washington, USA: relationship with other biomarkers of contaminant exposure
    • Myers M.S., Johnson L.L., Hom T., Collier T.K., Stein J.E., Varanasi U. Toxicopathic hepatic lesions in subadult English sole (Pleuronectes vetulus) from Puget Sound, Washington, USA: relationship with other biomarkers of contaminant exposure. Mar. Environ. Res. 1998, 45:47-67.
    • (1998) Mar. Environ. Res. , vol.45 , pp. 47-67
    • Myers, M.S.1    Johnson, L.L.2    Hom, T.3    Collier, T.K.4    Stein, J.E.5    Varanasi, U.6
  • 59
    • 0029022990 scopus 로고
    • Effect of 2, 3, 4, 7, 8-pentachlorodibenzofuran and its analogues on induction of sister chromatid exchanges in cultured human lymphocytes
    • Nagayama J., Nagayama M., Haraguchi K., Kuroki H., Masuda Y. Effect of 2, 3, 4, 7, 8-pentachlorodibenzofuran and its analogues on induction of sister chromatid exchanges in cultured human lymphocytes. Fukuoka Igaku Zasshi 1995, 86:184-189.
    • (1995) Fukuoka Igaku Zasshi , vol.86 , pp. 184-189
    • Nagayama, J.1    Nagayama, M.2    Haraguchi, K.3    Kuroki, H.4    Masuda, Y.5
  • 60
    • 0032781178 scopus 로고    scopus 로고
    • Induction of sister chromatid exchanges in cultured human lymphocytes with methylsulphonyl PCB congeners
    • Nagayama J., Nagayama M., Haraguchi K., Kuroki H., Masuda Y. Induction of sister chromatid exchanges in cultured human lymphocytes with methylsulphonyl PCB congeners. Fukuoka Igaku Zasshi 1999, 90:238-245.
    • (1999) Fukuoka Igaku Zasshi , vol.90 , pp. 238-245
    • Nagayama, J.1    Nagayama, M.2    Haraguchi, K.3    Kuroki, H.4    Masuda, Y.5
  • 61
    • 0028630693 scopus 로고
    • Effects of highly toxic organochlorine compounds retained in human body on induction of sister chromatid exchanges in cultured human lymphocytes
    • Nagayama J., Nagayama M., Iida T., Hirakawa H., Matsueda T., Masuda Y. Effects of highly toxic organochlorine compounds retained in human body on induction of sister chromatid exchanges in cultured human lymphocytes. Chemosphere 1994, 29:2349-2354.
    • (1994) Chemosphere , vol.29 , pp. 2349-2354
    • Nagayama, J.1    Nagayama, M.2    Iida, T.3    Hirakawa, H.4    Matsueda, T.5    Masuda, Y.6
  • 62
    • 0035042956 scopus 로고    scopus 로고
    • Comparison between "Yusho" patients and healthy Japanese in contamination level of dioxins and related chemicals and frequency of sister chromatid exchanges
    • Nagayama J., Nagayama M., Iida T., Hirakawa H., Matsueda T., Ohki M., Tsuji H. Comparison between "Yusho" patients and healthy Japanese in contamination level of dioxins and related chemicals and frequency of sister chromatid exchanges. Chemosphere 2001, 43:931-936.
    • (2001) Chemosphere , vol.43 , pp. 931-936
    • Nagayama, J.1    Nagayama, M.2    Iida, T.3    Hirakawa, H.4    Matsueda, T.5    Ohki, M.6    Tsuji, H.7
  • 63
    • 0025732355 scopus 로고
    • The effect of organochlorine compounds on the induction of sister chromatid exchanges in cultured human lymphocytes
    • Nagayama J., Nagayama M., Wada K., Iida T., Hirakawa H., Matsueda T., Masuda Y. The effect of organochlorine compounds on the induction of sister chromatid exchanges in cultured human lymphocytes. Fukuoka Igaku Zasshi 1991, 82:221-227.
    • (1991) Fukuoka Igaku Zasshi , vol.82 , pp. 221-227
    • Nagayama, J.1    Nagayama, M.2    Wada, K.3    Iida, T.4    Hirakawa, H.5    Matsueda, T.6    Masuda, Y.7
  • 64
    • 0018935422 scopus 로고
    • In vitro binding of hexachlorobiphenyl to DNA and proteins
    • Narbonne J.F., Daubeze M. In vitro binding of hexachlorobiphenyl to DNA and proteins. Toxicology 1980, 16:173-175.
    • (1980) Toxicology , vol.16 , pp. 173-175
    • Narbonne, J.F.1    Daubeze, M.2
  • 65
    • 84928697164 scopus 로고    scopus 로고
    • NTP, Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (gavage studies), Natl Toxicol Program. Tech Rep. Ser
    • NTP, Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (gavage studies), Natl Toxicol Program. Tech Rep. Ser (2006) 1-258.
    • (2006) , pp. 1-258
  • 66
    • 0029803656 scopus 로고    scopus 로고
    • Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer
    • Oakley G.G., Devanaboyina U., Robertson L.W., Gupta R.C. Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer. Chem. Res. Toxicol. 1996, 9:1285-1292.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 1285-1292
    • Oakley, G.G.1    Devanaboyina, U.2    Robertson, L.W.3    Gupta, R.C.4
  • 67
    • 0029972543 scopus 로고    scopus 로고
    • Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling
    • Oakley G.G., Robertson L.W., Gupta R.C. Analysis of polychlorinated biphenyl-DNA adducts by 32P-postlabeling. Carcinogenesis 1996, 17:109-114.
    • (1996) Carcinogenesis , vol.17 , pp. 109-114
    • Oakley, G.G.1    Robertson, L.W.2    Gupta, R.C.3
  • 68
    • 58149263291 scopus 로고    scopus 로고
    • Mortality after exposure to polychlorinated biphenyls and polychlorinated dibenzofurans: a 40-year follow-up study of Yusho patients
    • Onozuka D., Yoshimura T., Kaneko S., Furue M. Mortality after exposure to polychlorinated biphenyls and polychlorinated dibenzofurans: a 40-year follow-up study of Yusho patients. Am. J. Epidemiol. 2009, 169:86-95.
    • (2009) Am. J. Epidemiol. , vol.169 , pp. 86-95
    • Onozuka, D.1    Yoshimura, T.2    Kaneko, S.3    Furue, M.4
  • 69
    • 0020582855 scopus 로고
    • Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships
    • Parkinson A., Safe S.H., Robertson L.W., Thomas P.E., Ryan D.E., Reik L.M., Levin W. Immunochemical quantitation of cytochrome P-450 isozymes and epoxide hydrolase in liver microsomes from polychlorinated or polybrominated biphenyl-treated rats. A study of structure-activity relationships. J. Biol. Chem. 1983, 258:5967-5976.
    • (1983) J. Biol. Chem. , vol.258 , pp. 5967-5976
    • Parkinson, A.1    Safe, S.H.2    Robertson, L.W.3    Thomas, P.E.4    Ryan, D.E.5    Reik, L.M.6    Levin, W.7
  • 70
    • 0037138479 scopus 로고    scopus 로고
    • DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites
    • Pereg D., Robertson L.W., Gupta R.C. DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites. Chem. Biol. Interact. 2002, 139:129-144.
    • (2002) Chem. Biol. Interact. , vol.139 , pp. 129-144
    • Pereg, D.1    Robertson, L.W.2    Gupta, R.C.3
  • 71
    • 0035964988 scopus 로고    scopus 로고
    • Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice
    • Pereg D., Tampal N., Espandiari P., Robertson L.W. Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice. Chem. Biol. Interact. 2001, 137:243-258.
    • (2001) Chem. Biol. Interact. , vol.137 , pp. 243-258
    • Pereg, D.1    Tampal, N.2    Espandiari, P.3    Robertson, L.W.4
  • 73
    • 0019517856 scopus 로고
    • Relationship of carcinogen-induced sister chromatid exchange and neoplastic cell transformation, international journal of cancer
    • Popescu N.C., Amsbaugh S.C., DiPaolo J.A. Relationship of carcinogen-induced sister chromatid exchange and neoplastic cell transformation, international journal of cancer. J. Int. Cancer 1981, 28:71-77.
    • (1981) J. Int. Cancer , vol.28 , pp. 71-77
    • Popescu, N.C.1    Amsbaugh, S.C.2    DiPaolo, J.A.3
  • 75
    • 77957233334 scopus 로고    scopus 로고
    • Protective effects of selenium against DNA adduct formation in Inuit environmentally exposed to PCBs
    • Ravoori S., Srinivasan C., Pereg D., Robertson L.W., Ayotte P., Gupta R.C. Protective effects of selenium against DNA adduct formation in Inuit environmentally exposed to PCBs. Environ. Int. 2010, 36:980-986.
    • (2010) Environ. Int. , vol.36 , pp. 980-986
    • Ravoori, S.1    Srinivasan, C.2    Pereg, D.3    Robertson, L.W.4    Ayotte, P.5    Gupta, R.C.6
  • 77
    • 77955005618 scopus 로고    scopus 로고
    • PK(a) values of the monohydroxylated polychlorinated biphenyls (OH-PCBs), polybrominated biphenyls (OH-PBBs), polychlorinated diphenyl ethers (OH-PCDEs), and polybrominated diphenyl ethers (OH-PBDEs)
    • Rayne S., Forest K. PK(a) values of the monohydroxylated polychlorinated biphenyls (OH-PCBs), polybrominated biphenyls (OH-PBBs), polychlorinated diphenyl ethers (OH-PCDEs), and polybrominated diphenyl ethers (OH-PBDEs). J. Environ. Sci. Health 2010, 45:1322-1346.
    • (2010) J. Environ. Sci. Health , vol.45 , pp. 1322-1346
    • Rayne, S.1    Forest, K.2
  • 78
    • 46649117639 scopus 로고    scopus 로고
    • Genotoxic effects of PCB 52 and PCB 77 on cultured human peripheral lymphocytes
    • Sandal S., Yilmaz B., Carpenter D.O. Genotoxic effects of PCB 52 and PCB 77 on cultured human peripheral lymphocytes. Mutat. Res. 2008, 654:88-92.
    • (2008) Mutat. Res. , vol.654 , pp. 88-92
    • Sandal, S.1    Yilmaz, B.2    Carpenter, D.O.3
  • 79
    • 0025805987 scopus 로고
    • Study of the separate and combined effects of the non-planar 2,5,2',5'- and the planar 3,4,3',4'-tetrachlorobiphenyl in liver and lymphocytes in vivo
    • Sargent L., Dragan Y.P., Erickson C., Laufer C.J., Pitot H.C. Study of the separate and combined effects of the non-planar 2,5,2',5'- and the planar 3,4,3',4'-tetrachlorobiphenyl in liver and lymphocytes in vivo. Carcinogenesis 1991, 12:793-800.
    • (1991) Carcinogenesis , vol.12 , pp. 793-800
    • Sargent, L.1    Dragan, Y.P.2    Erickson, C.3    Laufer, C.J.4    Pitot, H.C.5
  • 80
    • 0024461045 scopus 로고
    • In vitro chromosome damage due to PCB interactions
    • Sargent L., Roloff B., Meisner L. In vitro chromosome damage due to PCB interactions. Mutat. Res. 1989, 224:79-88.
    • (1989) Mutat. Res. , vol.224 , pp. 79-88
    • Sargent, L.1    Roloff, B.2    Meisner, L.3
  • 81
    • 0026603591 scopus 로고
    • Ploidy and specific karyotypic changes during promotion with phenobarbital, 2,5,2',5'-tetrachlorobiphenyl, and/or 3,4,3'4'-tetrachlorobiphenyl in rat liver
    • Sargent L.M., Sattler G.L., Roloff B., Xu Y.H., Sattler C.A., Meisner L., Pitot H.C. Ploidy and specific karyotypic changes during promotion with phenobarbital, 2,5,2',5'-tetrachlorobiphenyl, and/or 3,4,3'4'-tetrachlorobiphenyl in rat liver. Cancer Res. 1992, 52:955-962.
    • (1992) Cancer Res. , vol.52 , pp. 955-962
    • Sargent, L.M.1    Sattler, G.L.2    Roloff, B.3    Xu, Y.H.4    Sattler, C.A.5    Meisner, L.6    Pitot, H.C.7
  • 83
    • 79957815292 scopus 로고    scopus 로고
    • Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat)
    • Senthilkumar P.K., Klingelhutz A.J., Jacobus J.A., Lehmler H., Robertson L.W., Ludewig G. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicol. Lett. 2011, 204:64-70.
    • (2011) Toxicol. Lett. , vol.204 , pp. 64-70
    • Senthilkumar, P.K.1    Klingelhutz, A.J.2    Jacobus, J.A.3    Lehmler, H.4    Robertson, L.W.5    Ludewig, G.6
  • 84
    • 84857110702 scopus 로고    scopus 로고
    • PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK)
    • Senthilkumar P.K., Robertson L.W., Ludewig G. PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK). Toxicol. Appl. Pharmacol. 2012, 259:115-123.
    • (2012) Toxicol. Appl. Pharmacol. , vol.259 , pp. 115-123
    • Senthilkumar, P.K.1    Robertson, L.W.2    Ludewig, G.3
  • 85
    • 0016976989 scopus 로고
    • Metabolic activation of [14C] polychlorinated biphenyl mixtures by rate liver microsomes
    • Shimada T. Metabolic activation of [14C] polychlorinated biphenyl mixtures by rate liver microsomes. Bull. Environ. Contam. Toxicol. 1976, 16:26-32.
    • (1976) Bull. Environ. Contam. Toxicol. , vol.16 , pp. 26-32
    • Shimada, T.1
  • 86
    • 0019775640 scopus 로고
    • Covalent binding of polychlorinated biphenyls to proteins by reconstituted monooxygenase system containing cytochrome P-450
    • Shimada T., Imai Y., Sato R. Covalent binding of polychlorinated biphenyls to proteins by reconstituted monooxygenase system containing cytochrome P-450. Chem. Biol. Interact. 1981, 38:29-44.
    • (1981) Chem. Biol. Interact. , vol.38 , pp. 29-44
    • Shimada, T.1    Imai, Y.2    Sato, R.3
  • 87
    • 0017800868 scopus 로고
    • Covalent binding in vitro of polychlorinated biphenyls to microsomal macromolecules. Involvement of metabolic activation by a cytochrome P-450-linked mono-oxygenase system
    • Shimada T., Sato R. Covalent binding in vitro of polychlorinated biphenyls to microsomal macromolecules. Involvement of metabolic activation by a cytochrome P-450-linked mono-oxygenase system. Biochem. Pharmacol. 1978, 27:585-593.
    • (1978) Biochem. Pharmacol. , vol.27 , pp. 585-593
    • Shimada, T.1    Sato, R.2
  • 88
    • 0018954869 scopus 로고
    • Covalent binding of polychlorinated biphenyls to rat liver microsomes in vitro: nature of reactive metabolites and target macromolecules
    • Shimada T., Sato R. Covalent binding of polychlorinated biphenyls to rat liver microsomes in vitro: nature of reactive metabolites and target macromolecules. Toxicol. Appl. Pharmacol. 1980, 55:490-500.
    • (1980) Toxicol. Appl. Pharmacol. , vol.55 , pp. 490-500
    • Shimada, T.1    Sato, R.2
  • 89
    • 0021083093 scopus 로고
    • Activation of 3,4,3',4'-tetrachlorobiphenyl to protein-bound metabolites by rat liver microsomal cytochrome P-448-containing monooxygenase system
    • Shimada T., Sawabe Y. Activation of 3,4,3',4'-tetrachlorobiphenyl to protein-bound metabolites by rat liver microsomal cytochrome P-448-containing monooxygenase system. Toxicol. Appl. Pharmacol. 1983, 70:486-493.
    • (1983) Toxicol. Appl. Pharmacol. , vol.70 , pp. 486-493
    • Shimada, T.1    Sawabe, Y.2
  • 90
    • 0021224361 scopus 로고
    • Comparative studies on distribution and covalent tissue binding of 2,4,2',4'- and 3,4,3',4'-tetrachlorobiphenyl isomers in the rat
    • Shimada T., Sawabe Y. Comparative studies on distribution and covalent tissue binding of 2,4,2',4'- and 3,4,3',4'-tetrachlorobiphenyl isomers in the rat. Arch. Toxicol. 1984, 55:182-185.
    • (1984) Arch. Toxicol. , vol.55 , pp. 182-185
    • Shimada, T.1    Sawabe, Y.2
  • 91
    • 0022381226 scopus 로고
    • Interaction of 3,4,3',4'-tetrachlorobiphenyl metabolites formed by cytochrome P-450 in vitro with rat erythrocytes
    • Shimada T., Sawabe Y., Nakano Y. Interaction of 3,4,3',4'-tetrachlorobiphenyl metabolites formed by cytochrome P-450 in vitro with rat erythrocytes. Arch. Toxicol. 1985, 58:20-26.
    • (1985) Arch. Toxicol. , vol.58 , pp. 20-26
    • Shimada, T.1    Sawabe, Y.2    Nakano, Y.3
  • 93
    • 25844472235 scopus 로고    scopus 로고
    • The influence of N-dialkyl and other cationic substituents on DNA intercalation and genotoxicity
    • Snyder R.D., McNulty J., Zairov G., Ewing D.E., Hendry L.B. The influence of N-dialkyl and other cationic substituents on DNA intercalation and genotoxicity. Mutat. Res. 2005, 578:88-99.
    • (2005) Mutat. Res. , vol.578 , pp. 88-99
    • Snyder, R.D.1    McNulty, J.2    Zairov, G.3    Ewing, D.E.4    Hendry, L.B.5
  • 94
    • 77955512534 scopus 로고    scopus 로고
    • Thermodynamic and kinetic considerations for the reaction of semiquinone radicals to form superoxide and hydrogen peroxide
    • Song Y., Buettner G.R. Thermodynamic and kinetic considerations for the reaction of semiquinone radicals to form superoxide and hydrogen peroxide. Free Radical Biol. Med. 2010, 49:919-962.
    • (2010) Free Radical Biol. Med. , vol.49 , pp. 919-962
    • Song, Y.1    Buettner, G.R.2
  • 95
    • 55249085382 scopus 로고    scopus 로고
    • Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones
    • Song Y., Buettner G.R., Parkin S., Wagner B.A., Robertson L.W., Lehmler H.J. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. J. Org. Chem. 2008, 73:8296-8304.
    • (2008) J. Org. Chem. , vol.73 , pp. 8296-8304
    • Song, Y.1    Buettner, G.R.2    Parkin, S.3    Wagner, B.A.4    Robertson, L.W.5    Lehmler, H.J.6
  • 96
    • 67649836351 scopus 로고    scopus 로고
    • Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones
    • Song Y., Wagner B.A., Witmer J.R., Lehmler H.J., Buettner G.R. Nonenzymatic displacement of chlorine and formation of free radicals upon the reaction of glutathione with PCB quinones. Proc. Natl. Acad. Sci. USA 2009, 106:9725-9730.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 9725-9730
    • Song, Y.1    Wagner, B.A.2    Witmer, J.R.3    Lehmler, H.J.4    Buettner, G.R.5
  • 97
    • 33749681153 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and heavy metals (HMs) as well as their genotoxicity in soil after long-term wastewater irrigation
    • Song Y.F., Wilke B.M., Song X.Y., Gong P., Zhou Q.X., Yang G.F. Polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and heavy metals (HMs) as well as their genotoxicity in soil after long-term wastewater irrigation. Chemosphere 2006, 65:1859-1868.
    • (2006) Chemosphere , vol.65 , pp. 1859-1868
    • Song, Y.F.1    Wilke, B.M.2    Song, X.Y.3    Gong, P.4    Zhou, Q.X.5    Yang, G.F.6
  • 98
    • 64449088421 scopus 로고    scopus 로고
    • Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species
    • Spencer W.A., Lehmler H.J., Robertson L.W., Gupta R.C. Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species. Free Radical Biol. Med. 2009, 46:1346-1352.
    • (2009) Free Radical Biol. Med. , vol.46 , pp. 1346-1352
    • Spencer, W.A.1    Lehmler, H.J.2    Robertson, L.W.3    Gupta, R.C.4
  • 99
    • 0036223696 scopus 로고    scopus 로고
    • Sulfhydryl binding and topoisomerase inhibition by PCB metabolites
    • Srinivasan A., Robertson L.W., Ludewig G. Sulfhydryl binding and topoisomerase inhibition by PCB metabolites. Chem. Res. Toxicol. 2002, 15:497-505.
    • (2002) Chem. Res. Toxicol. , vol.15 , pp. 497-505
    • Srinivasan, A.1    Robertson, L.W.2    Ludewig, G.3
  • 100
    • 0018762405 scopus 로고
    • DNA single strand breaks caused by 2,2',5,5'-tetrachlorobiphenyl and its metabolites
    • Stadnicki S.S., Lin F.S., Allen J.R. DNA single strand breaks caused by 2,2',5,5'-tetrachlorobiphenyl and its metabolites. Res. Commun. Chem. Pathol. Pharmacol. 1979, 24:313-327.
    • (1979) Res. Commun. Chem. Pathol. Pharmacol. , vol.24 , pp. 313-327
    • Stadnicki, S.S.1    Lin, F.S.2    Allen, J.R.3
  • 102
    • 0345700242 scopus 로고    scopus 로고
    • Binding of polychlorinated biphenyls/metabolites to hemoglobin
    • Tampal N., Myers S., Robertson L.W. Binding of polychlorinated biphenyls/metabolites to hemoglobin. Toxicol. Lett. 2003, 142:53-60.
    • (2003) Toxicol. Lett. , vol.142 , pp. 53-60
    • Tampal, N.1    Myers, S.2    Robertson, L.W.3
  • 103
    • 0025300958 scopus 로고
    • Structural chromosome aberrations and industrial waste
    • Tretjak Z., Volavsek C., Beckmann S.L. Structural chromosome aberrations and industrial waste. Lancet 1990, 335:1288.
    • (1990) Lancet , vol.335 , pp. 1288
    • Tretjak, Z.1    Volavsek, C.2    Beckmann, S.L.3
  • 104
    • 33847231231 scopus 로고    scopus 로고
    • Increased liver and lupus mortalities in 24-year follow-up of the Taiwanese people highly exposed to polychlorinated biphenyls and dibenzofurans
    • Tsai P.C., Ko Y.C., Huang W., Liu H.S., Guo Y.L. Increased liver and lupus mortalities in 24-year follow-up of the Taiwanese people highly exposed to polychlorinated biphenyls and dibenzofurans. Sci. Total Environ. 2007, 374:216-222.
    • (2007) Sci. Total Environ. , vol.374 , pp. 216-222
    • Tsai, P.C.1    Ko, Y.C.2    Huang, W.3    Liu, H.S.4    Guo, Y.L.5
  • 105
    • 0026062878 scopus 로고
    • Micronucleus formation in cultured human keratinocytes: involvement of intercellular bioactivation
    • van Pelt F.N., Haring R.M., Weterings P.J. Micronucleus formation in cultured human keratinocytes: involvement of intercellular bioactivation. Toxicol. In Vitro 1991, 5:515-518.
    • (1991) Toxicol. In Vitro , vol.5 , pp. 515-518
    • van Pelt, F.N.1    Haring, R.M.2    Weterings, P.J.3
  • 107
    • 0033758924 scopus 로고    scopus 로고
    • A cytogenetic study on the teaching staff of a polluted school with a questionable increased incidence of malignancies
    • Wiesner G., Wild K.J., Gruber M., Lindner R., Taeger K. A cytogenetic study on the teaching staff of a polluted school with a questionable increased incidence of malignancies. Int. J. Hyg. Environ. Health 2000, 203:141-146.
    • (2000) Int. J. Hyg. Environ. Health , vol.203 , pp. 141-146
    • Wiesner, G.1    Wild, K.J.2    Gruber, M.3    Lindner, R.4    Taeger, K.5
  • 108
    • 0025811131 scopus 로고
    • Monitoring the exposure of rats to benzo[a]pyrene by the determination of mutagenic activity in excreta, chromosome aberrations and sister chromatid exchanges in peripheral blood cells, and DNA adducts in peripheral blood lymphocytes and liver
    • Willems M.I., Roggeband R., Baan R.A., Wilmer J.W., de Raat W.K., Lohman P.H. Monitoring the exposure of rats to benzo[a]pyrene by the determination of mutagenic activity in excreta, chromosome aberrations and sister chromatid exchanges in peripheral blood cells, and DNA adducts in peripheral blood lymphocytes and liver. Mutagenesis 1991, 6:151-158.
    • (1991) Mutagenesis , vol.6 , pp. 151-158
    • Willems, M.I.1    Roggeband, R.2    Baan, R.A.3    Wilmer, J.W.4    de Raat, W.K.5    Lohman, P.H.6
  • 109
    • 0018400060 scopus 로고
    • The metabolically mediated DNA damage and subsequent DNA repair by 4-chlorobiphenyl in Chinese hamster ovary cells
    • Wong A., Basrur P., Safe S. The metabolically mediated DNA damage and subsequent DNA repair by 4-chlorobiphenyl in Chinese hamster ovary cells. Res. Commun. Chem. Pathol. Pharmacol. 1979, 24:543-550.
    • (1979) Res. Commun. Chem. Pathol. Pharmacol. , vol.24 , pp. 543-550
    • Wong, A.1    Basrur, P.2    Safe, S.3
  • 110
    • 0017133022 scopus 로고
    • The in vitro metabolism, macromolecular binding and bacterial mutagenicity of 4-chloribiphenyl, a model PCB substrate
    • Wyndham C., Devenish J., Safe S. The in vitro metabolism, macromolecular binding and bacterial mutagenicity of 4-chloribiphenyl, a model PCB substrate. Res. Commun. Chem. Pathol. Pharmacol. 1976, 15:563-570.
    • (1976) Res. Commun. Chem. Pathol. Pharmacol. , vol.15 , pp. 563-570
    • Wyndham, C.1    Devenish, J.2    Safe, S.3
  • 111
    • 0017845113 scopus 로고
    • In vitro metabolism of 4-chlorobiphenyl by control and induced rat liver microsomes
    • Wyndham C., Safe S. In vitro metabolism of 4-chlorobiphenyl by control and induced rat liver microsomes. Biochemistry 1978, 17:208-215.
    • (1978) Biochemistry , vol.17 , pp. 208-215
    • Wyndham, C.1    Safe, S.2
  • 112
    • 77957242414 scopus 로고    scopus 로고
    • Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites
    • Xie W., Wang K., Robertson L.W., Ludewig G. Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites. Environ. Int. 2010, 36:950-961.
    • (2010) Environ. Int. , vol.36 , pp. 950-961
    • Xie, W.1    Wang, K.2    Robertson, L.W.3    Ludewig, G.4
  • 113
    • 0026683779 scopus 로고
    • Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis
    • Yamasaki H., Mesnil M., Nakazawa H. Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis. Toxicol. Lett. 1992, 64-65:597-604.
    • (1992) Toxicol. Lett. , pp. 597-604
    • Yamasaki, H.1    Mesnil, M.2    Nakazawa, H.3
  • 114
    • 0025184162 scopus 로고
    • Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals
    • Zeiger E., Haseman J.K., Shelby M.D., Margolin B.H., Tennant R.W. Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals. Environ. Mol. Mutagen. 1990, 16(Suppl. 18):1-14.
    • (1990) Environ. Mol. Mutagen. , vol.16 , Issue.SUPPL. 18 , pp. 1-14
    • Zeiger, E.1    Haseman, J.K.2    Shelby, M.D.3    Margolin, B.H.4    Tennant, R.W.5
  • 115
    • 35448982010 scopus 로고    scopus 로고
    • Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells
    • Zettner M.A., Flor S., Ludewig G., Wagner J., Robertson L.W., Lehmann L. Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells. Toxicol. Sci. 2007, 100:88-98.
    • (2007) Toxicol. Sci. , vol.100 , pp. 88-98
    • Zettner, M.A.1    Flor, S.2    Ludewig, G.3    Wagner, J.4    Robertson, L.W.5    Lehmann, L.6
  • 116
    • 1942518323 scopus 로고    scopus 로고
    • Characterization and quantitative analysis of DNA adducts formed from lower chlorinated PCB-derived quinones
    • Zhao S., Narang A., Ding X., Eadon G. Characterization and quantitative analysis of DNA adducts formed from lower chlorinated PCB-derived quinones. Chem. Res. Toxicol. 2004, 17:502-511.
    • (2004) Chem. Res. Toxicol. , vol.17 , pp. 502-511
    • Zhao, S.1    Narang, A.2    Ding, X.3    Eadon, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.