Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons

Free Radical Biology and Medicine

Volumn 45, Issue 5, 2008, Pages 585-591

  Jeong, Yo Chan ^a   Walker, Nigel J ^b   Burgin, Deborah E ^c   Kissling, Grace ^b   Gupta, Mayetri ^d   Kupper, Lawrence ^d   Birnbaum, Linda S ^c   Swenberg, James A ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d IL   (United States)

Author keywords

Carcinogenesis; M1dG; Oxidative DNA lesion; PCBs; Polychlorinated aromatic hydrocarbons; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CORN OIL; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON; 3 (2' DEOXY BETA D ERYTHRO PENTOFURANOSYL)PYRIMIDO(1,2 ALPHA)PURIN 10(3H) ONE; 3-(2'-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)PYRIMIDO(1,2-ALPHA)PURIN-10(3H)-ONE; PURINE NUCLEOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BRAIN TISSUE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; FEMALE; LIVER; LONG TERM EXPOSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; ANIMAL; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; METABOLISM; NEOPLASM; TIME;

MUS; RATTUS; ZEA MAYS;

ANIMALS; DNA ADDUCTS; FEMALE; LIVER; MICE; MOLECULAR STRUCTURE; NEOPLASMS; POLYCHLORINATED BIPHENYLS; PURINE NUCLEOSIDES; RATS; TIME FACTORS;

EID: 48649084094     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.04.043     Document Type: Article

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