The influence of N-dialkyl and other cationic substituents on DNA intercalation and genotoxicity

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 578, Issue 1-2, 2005, Pages 88-99

  Snyder, R D ^a   McNulty, J ^a   Zairov, G ^a   Ewing, D E ^b   Hendry, L B ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Accelerated Pharmaceuticals Inc   (United States)

Author keywords

Bleomycin amplification; Chinese hamster V79 cells; Computational modeling; Genotoxicity; Topoisomerase II

Indexed keywords

1,1,2 TRIPHENYLETHYLENE DERIVATIVE; ACRIDINE DERIVATIVE; ALKYL GROUP; BENZOPHENONE DERIVATIVE; CATION; INTERCALATING AGENT; PHENOTHIAZINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CHINESE HAMSTER; GENOTOXICITY; INTERCALATION COMPLEX; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BLEOMYCIN; CATIONS; CELL LINE; COMPUTATIONAL BIOLOGY; CRICETINAE; CRICETULUS; DNA; FRAMESHIFT MUTATION; INTERCALATING AGENTS; MOLECULAR STRUCTURE; MUTAGENICITY TESTS; MUTAGENS;

CRICETULUS GRISEUS;

EID: 25844472235     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.03.022     Document Type: Article

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