메뉴 건너뛰기




Volumn 288, Issue 22, 2013, Pages 15455-15465

A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor κB (NFκB)-mediated cardiac transcription

Author keywords

[No Author keywords available]

Indexed keywords

BCL-2 FAMILY PROTEINS; MITOCHONDRIAL APOPTOSIS; MURINE EMBRYONIC FIBROBLASTS; NUCLEAR DISTRIBUTION; NUCLEAR TRANSLOCATIONS; POSTTRANSLATIONAL REGULATION; PUTATIVE FUNCTIONS; TUMOR NECROSIS FACTORS;

EID: 84878419623     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.452342     Document Type: Article
Times cited : (16)

References (47)
  • 1
    • 77951901715 scopus 로고    scopus 로고
    • Cell death in the pathogenesis of heart disease: Mechanisms and significance
    • Whelan, R. S., Kaplinskiy, V., and Kitsis, R. N. (2010) Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu. Rev. Physiol. 72, 19-44
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 19-44
    • Whelan, R.S.1    Kaplinskiy, V.2    Kitsis, R.N.3
  • 2
    • 77956403913 scopus 로고    scopus 로고
    • Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure
    • Dorn, G. W., 2nd (2010) Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure. Cell Cycle 9, 3442-3448
    • (2010) Cell Cycle , vol.9 , pp. 3442-3448
    • Dorn II, G.W.1
  • 3
    • 38349184844 scopus 로고    scopus 로고
    • Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation
    • Diwan, A., Wansapura, J., Syed, F. M., Matkovich, S. J., Lorenz, J. N., and Dorn, G. W., 2nd (2008) Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation 117, 396-404
    • (2008) Circulation , vol.117 , pp. 396-404
    • Diwan, A.1    Wansapura, J.2    Syed, F.M.3    Matkovich, S.J.4    Lorenz, J.N.5    Dorn II, G.W.6
  • 4
    • 78049445419 scopus 로고    scopus 로고
    • Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes
    • Fujimoto, K., Ford, E. L., Tran, H., Wice, B. M., Crosby, S. D., Dorn, G. W., 2nd, and Polonsky, K. S. (2010) Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes. J. Clin. Invest. 120, 4031-4039
    • (2010) J. Clin. Invest. , vol.120 , pp. 4031-4039
    • Fujimoto, K.1    Ford, E.L.2    Tran, H.3    Wice, B.M.4    Crosby, S.D.5    Dorn II, G.W.6    Polonsky, K.S.7
  • 5
    • 0036061644 scopus 로고    scopus 로고
    • Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy
    • DOI 10.1038/nm719
    • Yussman, M. G., Toyokawa, T., Odley, A., Lynch, R. A., Wu, G., Colbert, M. C., Aronow, B. J., Lorenz, J. N., and Dorn, G. W., 2nd (2002) Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy. Nat. Med. 8, 725-730 (Pubitemid 34778726)
    • (2002) Nature Medicine , vol.8 , Issue.7 , pp. 725-730
    • Yussman, M.G.1    Toyokawa, T.2    Odley, A.3    Lynch, R.A.4    Wu, G.5    Colbert, M.C.6    Aronow, B.J.7    Lorenz, J.N.8    Dorn II, G.W.9
  • 6
    • 77952683069 scopus 로고    scopus 로고
    • Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy
    • Chen, Y., Lewis, W., Diwan, A., Cheng, E. H., Matkovich, S. J., and Dorn, G. W., 2nd (2010) Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy. Proc. Natl. Acad. Sci. U.S.A. 107, 9035-9042
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 9035-9042
    • Chen, Y.1    Lewis, W.2    Diwan, A.3    Cheng, E.H.4    Matkovich, S.J.5    Dorn II, G.W.6
  • 7
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
    • DOI 10.1016/S0006-291X(03)00615-6
    • Scorrano, L., and Korsmeyer, S. J. (2003) Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun. 304, 437-444 (Pubitemid 36506515)
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , Issue.3 , pp. 437-444
    • Scorrano, L.1    Korsmeyer, S.J.2
  • 10
    • 77952700862 scopus 로고    scopus 로고
    • Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway
    • Kitsis, R. N., and Molkentin, J. D. (2010) Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway. Proc. Natl. Acad. Sci. U.S.A. 107, 9031-9032
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 9031-9032
    • Kitsis, R.N.1    Molkentin, J.D.2
  • 11
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D., Nuñez, G., Milliman, C., Schreiber, R. D., and Korsmeyer, S. J. (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348, 334-336 (Pubitemid 120029101)
    • (1990) Nature , vol.348 , Issue.6299 , pp. 334-336
    • Hockenbery, D.1    Ninez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 12
    • 0027282044 scopus 로고
    • bcl-x, A bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • DOI 10.1016/0092-8674(93)90508-N
    • Boise, L. H., González-García, M., Postema, C. E., Ding, L., Lindsten, T., Turka, L. A., Mao, X., Nuñez, G., and Thompson, C. B. (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74, 597-608 (Pubitemid 23259741)
    • (1993) Cell , vol.74 , Issue.4 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3    Ding, L.4    Lindsten, T.5    Turka, L.A.6    Mao, X.7    Nunez, G.8    Thompson, C.B.9
  • 14
    • 0027225445 scopus 로고
    • Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2β protein restores function as a regulator of cell survival
    • Tanaka, S., Saito, K., and Reed, J. C. (1993) Structure-function analysis of the Bcl-2 oncoprotein: addition of a heterologous transmembrane domain to portions of the Bcl-2 β protein restores function as a regulator of cell survival. J. Biol. Chem. 268, 10920-10926 (Pubitemid 23162274)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.15 , pp. 10920-10926
    • Tanaka, S.1    Saito, K.2    Reed, J.C.3
  • 18
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
    • Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S., and Baltimore, D. (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature 376, 167-170
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 20
    • 84870591476 scopus 로고    scopus 로고
    • Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions
    • Decker, K. F., Zheng, D., He, Y., Bowman, T., Edwards, J. R., and Jia, L. (2012) Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions. Nucleic Acids Res. 40, 10765-10779
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10765-10779
    • Decker, K.F.1    Zheng, D.2    He, Y.3    Bowman, T.4    Edwards, J.R.5    Jia, L.6
  • 25
    • 0034957413 scopus 로고    scopus 로고
    • Effect of NF-κB inhibition on TNF-α-induced apoptosis and downstream pathways in cardiomyocytes
    • DOI 10.1006/jmcc.2001.1385
    • Bergmann, M. W., Loser, P., Dietz, R., and von Harsdorf, R. (2001) Effect of NF-κB inhibition on TNF-α-induced apoptosis and downstream pathways in cardiomyocytes. J. Mol. Cell Cardiol. 33, 1223-1232 (Pubitemid 32579287)
    • (2001) Journal of Molecular and Cellular Cardiology , vol.33 , Issue.6 , pp. 1223-1232
    • Bergmann, M.W.1    Loser, P.2    Dietz, R.3    Harsdorf, R.V.4
  • 27
    • 1942470419 scopus 로고    scopus 로고
    • Tumor Necrosis Factor Receptors 1 and 2 Differentially Regulate Survival, Cardiac Dysfunction, and Remodeling in Transgenic Mice with Tumor Necrosis Factor-α-Induced Cardiomyopathy
    • DOI 10.1161/01.CIR.0000124227.00670.AB
    • Higuchi, Y., McTiernan, C. F., Frye, C. B., McGowan, B. S., Chan, T. O., and Feldman, A. M. (2004) Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-α-induced cardiomyopathy. Circulation 109, 1892-1897 (Pubitemid 38509125)
    • (2004) Circulation , vol.109 , Issue.15 , pp. 1892-1897
    • Higuchi, Y.1    McTiernan, C.F.2    Frye, C.B.3    McGowan, B.S.4    Chan, T.O.5    Feldman, A.M.6
  • 29
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 30
    • 0031857150 scopus 로고    scopus 로고
    • Tumor necrosis factor in congestive heart failure: A mechanism of disease for the new millennium?
    • Ceconi, C., Curello, S., Bachetti, T., Corti, A., and Ferrari, R. (1998) Tumor necrosis factor in congestive heart failure: a mechanism of disease for the new millennium? Prog. Cardiovasc. Dis. 41, 25-30 (Pubitemid 28381712)
    • (1998) Progress in Cardiovascular Diseases , vol.41 , Issue.1 SUPPL. , pp. 25-30
    • Ceconi, C.1    Curello, S.2    Bachetti, T.3    Corti, A.4    Ferrari, R.5
  • 31
    • 79955605472 scopus 로고    scopus 로고
    • Multiple facets of NF-κB in the heart: To be or not to NF-κB
    • Gordon, J. W., Shaw, J. A., and Kirshenbaum, L. A. (2011) Multiple facets of NF-κB in the heart: to be or not to NF-κB. Circ. Res. 108, 1122-1132
    • (2011) Circ. Res. , vol.108 , pp. 1122-1132
    • Gordon, J.W.1    Shaw, J.A.2    Kirshenbaum, L.A.3
  • 32
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • DOI 10.1126/science.1071924
    • Chen, G., and Goeddel, D. V. (2002) TNF-R1 signaling: a beautiful pathway. Science 296, 1634-1635 (Pubitemid 34579145)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 33
    • 0028113218 scopus 로고
    • Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
    • DOI 10.1016/0092-8674(94)90202-X
    • Boyd, J. M., Malstrom, S., Subramanian, T., Venkatesh, L. K., Schaeper, U., Elangovan, B., D'Sa-Eipper, C., and Chinnadurai, G. (1994) Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79, 341-351 (Pubitemid 24324923)
    • (1994) Cell , vol.79 , Issue.2 , pp. 341-351
    • Boyd, J.M.1    Malstrom, S.2    Subramanian, T.3    Venkatesh, L.K.4    Schaeper, U.5    Elangovan, B.6    D'Sa-Eipper, C.7    Chinnadurai, G.8
  • 34
    • 70449091753 scopus 로고    scopus 로고
    • Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis
    • Kim, H., Tu, H. C., Ren, D., Takeuchi, O., Jeffers, J. R., Zambetti, G. P., Hsieh, J. J., and Cheng, E. H. (2009) Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. Mol. Cell 36, 487-499
    • (2009) Mol. Cell , vol.36 , pp. 487-499
    • Kim, H.1    Tu, H.C.2    Ren, D.3    Takeuchi, O.4    Jeffers, J.R.5    Zambetti, G.P.6    Hsieh, J.J.7    Cheng, E.H.8
  • 37
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • DOI 10.1038/nature07006, PII NATURE07006
    • Sandoval, H., Thiagarajan, P., Dasgupta, S. K., Schumacher, A., Prchal, J. T., Chen, M., and Wang, J. (2008) Essential role for Nix in autophagic maturation of erythroid cells. Nature 454, 232-235 (Pubitemid 351969889)
    • (2008) Nature , vol.454 , Issue.7201 , pp. 232-235
    • Sandoval, H.1    Thiagarajan, P.2    Dasgupta, S.K.3    Schumacher, A.4    Prchal, J.T.5    Chen, M.6    Wang, J.7
  • 38
    • 77955514158 scopus 로고    scopus 로고
    • Mitochondrial pruning by Nix and BNip3: An essential function for cardiac-expressed death factors
    • Dorn, G. W., 2nd (2010) Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors. J. Cardiovasc. Transl. Res. 3, 374-383
    • (2010) J. Cardiovasc. Transl. Res. , vol.3 , pp. 374-383
    • Dorn II, G.W.1
  • 39
    • 0022497852 scopus 로고
    • Genetic control of programmed cell death in the nematode C. elegans
    • Ellis, H. M., and Horvitz, H. R. (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44, 817-829 (Pubitemid 16045328)
    • (1986) Cell , vol.44 , Issue.6 , pp. 817-829
    • Ellis, H.M.1    Horvitz, H.R.2
  • 42
    • 76349114046 scopus 로고    scopus 로고
    • Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1
    • Chang, N. C., Nguyen, M., Germain, M., and Shore, G. C. (2010) Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J. 29, 606-618
    • (2010) EMBO J. , vol.29 , pp. 606-618
    • Chang, N.C.1    Nguyen, M.2    Germain, M.3    Shore, G.C.4
  • 43
    • 67649547153 scopus 로고    scopus 로고
    • Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak
    • Klee, M., Pallauf, K., Alcalá, S., Fleischer, A., and Pimentel-Muiños, F. X. (2009) Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak. EMBO J. 28, 1757-1768
    • (2009) EMBO J. , vol.28 , pp. 1757-1768
    • Klee, M.1    Pallauf, K.2    Alcalá, S.3    Fleischer, A.4    Pimentel-Muiños, F.X.5
  • 45
    • 0034676339 scopus 로고    scopus 로고
    • The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism
    • DOI 10.1038/sj.onc.1203929
    • Cizeau, J., Ray, R., Chen, G., Gietz, R. D., and Greenberg, A. H. (2000) The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism. Oncogene 19, 5453-5463 (Pubitemid 32000912)
    • (2000) Oncogene , vol.19 , Issue.48 , pp. 5453-5463
    • Cizeau, J.1    Ray, R.2    Chen, G.3    Gietz, R.D.4    Greenberg, A.H.5
  • 46
    • 0036716281 scopus 로고    scopus 로고
    • The BCL2 family: Regulators of the cellular life-or-death switch
    • DOI 10.1038/nrc883
    • Cory, S., and Adams, J. M. (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2, 647-656 (Pubitemid 37328916)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.9 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 47
    • 0035844238 scopus 로고    scopus 로고
    • Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death
    • Mercatante, D. R., Bortner, C. D., Cidlowski, J. A., and Kole, R. (2001) Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death. J. Biol. Chem. 276, 16411-16417
    • (2001) J. Biol. Chem. , vol.276 , pp. 16411-16417
    • Mercatante, D.R.1    Bortner, C.D.2    Cidlowski, J.A.3    Kole, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.