β1-Adrenergic receptor-mediated HO-1 induction, via PI3K and p38 MAPK, by isoproterenol in RAW 264.7 cells leads to inhibition of HMGB1 release in LPS-activated RAW 264.7 cells and increases in survival rate of CLP-induced septic mice

Biochemical Pharmacology

Volumn 82, Issue 7, 2011, Pages 769-777

  Ha, Yu Mi ^a   Ham, Sun Ah ^a   Kim, Young Min ^a   Lee, Young Soo ^a   Kim, Hye Jung ^a   Seo, Han Geuk ^a   Lee, Jae Heun ^a   Park, Min Kyu ^b   Chang, Ki Churl ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

1 Adrenergic receptor; Heme oxygenase 1; Isoproterenol; Mice; Sepsis

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; DOBUTAMINE; HEME OXYGENASE 1; HIGH MOBILITY GROUP B1 PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPRENALINE; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGENASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; SALBUTAMOL; TRANSCRIPTION FACTOR NRF2; I KAPPA B KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; HEART; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SEPSIS; SURVIVAL RATE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CECUM; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HEART MUSCLE; LIGATION; METABOLISM; MORTALITY; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT; PUNCTURE; STENOSIS, OCCLUSION AND OBSTRUCTION;

ANIMALS; CECUM; CELL LINE; CONSTRICTION, PATHOLOGIC; HEME OXYGENASE-1; HMGB1 PROTEIN; I-KAPPA B KINASE; ISOPROTERENOL; LIGATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; MYOCARDIUM; NF-E2-RELATED FACTOR 2; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN TRANSPORT; PUNCTURES; RECEPTORS, ADRENERGIC, BETA-1; SEPSIS; SURVIVAL RATE;

EID: 80051802240     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.06.041     Document Type: Article

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