Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy

Cellular and Molecular Life Sciences

Volumn 70, Issue 11, 2013, Pages 1985-2002

  Le Fourn, Valerie ^a,c   Park, Sujin ^b   Jang, Insook ^b   Gaplovska Kysela, Katarina ^a,d   Guhl, Bruno ^a   Lee, Yangsin ^b   Cho, Jin Won ^b   Zuber, Christian ^a   Roth, Jürgen ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Yonsei University   (South Korea)

^c Selexis   (Switzerland)

^d Physics and Informatics   (Slovakia)

Author keywords

EDEM1; Endoplasmic reticulum; ERAD; Fibrinogen dimer; Protein assembly; Protein dislocation; Selective autophagy

Indexed keywords

ADAPTOR PROTEIN; COAT PROTEIN COMPLEX II; ENDOPLASMIC RETICULUM DEGRADATION ENHANCING ALPHA MANNOSIDASE LIKE PROTEIN 1; FIBRINOGEN; NEIGHBOR OF BRCA1 GENE 1 PROTEIN; PROTEIN P62; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CELL STRAIN HEPG2; COATED VESICLE; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOGOLD ELECTRON MICROSCOPY; PROTEIN AGGREGATION; PROTEIN DEGRADATION; SELECTIVE AUTOPHAGY;

AUTOPHAGY; CYTOPLASMIC VESICLES; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; FIBRINOGEN; GLYCOPROTEINS; GOLGI APPARATUS; HEP G2 CELLS; HUMANS; MEMBRANE PROTEINS; PROTEIN FOLDING; PROTEIN TRANSPORT;

EID: 84878271845     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1236-6     Document Type: Article

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