EDEM1 accelerates the trimming of α1,2-linked mannose on the C branch of N-glycans

Glycobiology

Volumn 20, Issue 5, 2010, Pages 567-575

  Hosokawa, Nobuko ^a   Tremblay, Linda O ^b   Sleno, Barry ^b   Kamiya, Yukiko ^c,d   Wada, Ikuo ^e   Nagata, Kazuhiro ^a   Kato, Koichi ^c,d,f   Herscovics, Annette ^b  

^a KYOTO UNIVERSITY   (Japan)

^b MCGILL UNIVERSITY   (Canada)

^c OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^d NAGOYA CITY UNIVERSITY   (Japan)

^e FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^f OCHANOMIZU UNIVERSITY   (Japan)

Author keywords

EDEM (ER degradation enhancing mannosidaselike protein); ERAD (ER associated degradation); Glycoprotein; Mannose trimming; N linked glycan

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALPHA MANNOSIDASE; ENDOPLASMIC RETICULUM DEGRADATION ENHANCING ALPHA MANNOSIDASE LIKE 1; GLYCAN; GLYCOPROTEIN; MANNOSE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE SYNTHESIS; CELL STRAIN HEPG2; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; GENE MUTATION; GENE OVEREXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN TARGETING; QUALITY CONTROL; WILD TYPE;

CELLS, CULTURED; ENDOPLASMIC RETICULUM; HUMANS; MANNOSE; MEMBRANE PROTEINS; POLYSACCHARIDES; STEREOISOMERISM;

EID: 77952811195     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwq001     Document Type: Article

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