Inhibitory phosphorylation of GSK-3β by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP)

American Journal of Physiology - Renal Physiology

Volumn 304, Issue 7, 2013, Pages

  Zhou, Xiaoming ^a   Wang, Hong ^a   Burg, Maurice B ^b   Ferraris, Joan D ^b  

^a Uniformed Services University of the Health Sciences   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Hypertonicity; Nuclear localization; P38 ; Phosphorylation; Transactivation

Indexed keywords

ALANINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MITOGEN ACTIVATED PROTEIN KINASE 14; NFAT5 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FIBROBLAST; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RNA INTERFERENCE; TRANSACTIVATION; WILD TYPE; ACTIVE TRANSPORT; ANIMAL; CELL STRAIN HEK293; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GLYCOGEN SYNTHASE KINASE 3; HEK293 CELLS; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 14; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SODIUM CHLORIDE; TRANSCRIPTION FACTORS;

MLCS; MLOWN;

EID: 84878215343     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00591.2012     Document Type: Article

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