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Volumn 31, Issue 42, 2012, Pages 4536-4549

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor

Author keywords

cancer; ddx17; ddx5; NFAT5; splicing; transcriptional coregulator

Indexed keywords

MESSENGER RNA; RNA HELICASE; RNA HELICASE DDX17; RNA HELICASE DDX5; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG;

EID: 84867745553     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.618     Document Type: Article
Times cited : (62)

References (75)
  • 1
    • 44449158814 scopus 로고    scopus 로고
    • Splicing, transcription, and chromatin: A menage a trois
    • Allemand E, Batsche E, Muchardt C. (2008). Splicing, transcription, and chromatin: a menage a trois. Curr Opin Genet Dev 18: 145-151.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 145-151
    • Allemand, E.1    Batsche, E.2    Muchardt, C.3
  • 3
    • 0037064150 scopus 로고    scopus 로고
    • Coordinate regulation of transcription and splicing by steroid receptor coregulators
    • Auboeuf D, Honig A, Berget SM, O'Malley BW. (2002). Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science 298: 416-419.
    • (2002) Science , vol.298 , pp. 416-419
    • Auboeuf, D.1    Honig, A.2    Berget, S.M.3    O'Malley, B.W.4
  • 4
    • 2942729848 scopus 로고    scopus 로고
    • Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer
    • Ayers M, Symmans WF, Stec J, Damokosh AI, Clark E, Hess K et al. (2004). Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer. J Clin Oncol 22: 2284-2293.
    • (2004) J Clin Oncol , vol.22 , pp. 2284-2293
    • Ayers, M.1    Symmans, W.F.2    Stec, J.3    Damokosh, A.I.4    Clark, E.5    Hess, K.6
  • 6
    • 35148874079 scopus 로고    scopus 로고
    • Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways
    • Barbier J, Dutertre M, Bittencourt D, Sanchez G, Gratadou L, de la Grange P et al. (2007). Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways. Mol Cell Biol 27: 7315-7333.
    • (2007) Mol Cell Biol , vol.27 , pp. 7315-7333
    • Barbier, J.1    Dutertre, M.2    Bittencourt, D.3    Sanchez, G.4    Gratadou, L.5    De La Grange, P.6
  • 7
    • 20044373828 scopus 로고    scopus 로고
    • The DEAD box protein p68: A novel transcriptional coactivator of the p53 tumour suppressor
    • Bates GJ, Nicol SM, Wilson BJ, Jacobs AM, Bourdon JC, Wardrop J et al. (2005). The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. Embo J 24: 543-553.
    • (2005) Embo J , vol.24 , pp. 543-553
    • Bates, G.J.1    Nicol, S.M.2    Wilson, B.J.3    Jacobs, A.M.4    Bourdon, J.C.5    Wardrop, J.6
  • 9
    • 51349121081 scopus 로고    scopus 로고
    • Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes
    • Bittencourt D, Dutertre M, Sanchez G, Barbier J, Gratadou L, Auboeuf D. (2008). Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes. Mol Cell Biol 28: 5811-5824.
    • (2008) Mol Cell Biol , vol.28 , pp. 5811-5824
    • Bittencourt, D.1    Dutertre, M.2    Sanchez, G.3    Barbier, J.4    Gratadou, L.5    Auboeuf, D.6
  • 10
    • 0037452652 scopus 로고    scopus 로고
    • Splicing regulation: The cell cycle connection
    • Blencowe BJ. (2003). Splicing regulation: the cell cycle connection. Curr Biol 13: R149-R151.
    • (2003) Curr Biol , vol.13
    • Blencowe, B.J.1
  • 11
    • 35648982347 scopus 로고    scopus 로고
    • Cellular response to hyperosmotic stresses
    • Burg MB, Ferraris JD, Dmitrieva NI. (2007). Cellular response to hyperosmotic stresses. Physiol Rev 87: 1441-1474.
    • (2007) Physiol Rev , vol.87 , pp. 1441-1474
    • Burg, M.B.1    Ferraris, J.D.2    Dmitrieva, N.I.3
  • 12
    • 51449107580 scopus 로고    scopus 로고
    • P68 RNA helicase (DDX5) alters activity of cis-and trans-acting factors of the alternative splicing of H-Ras
    • Camats M, Guil S, Kokolo M, Bach-Elias M. (2008). P68 RNA helicase (DDX5) alters activity of cis-and trans-acting factors of the alternative splicing of H-Ras. PLoS One 3: e2926.
    • (2008) PLoS One , vol.3
    • Camats, M.1    Guil, S.2    Kokolo, M.3    Bach-Elias, M.4
  • 13
    • 33749125424 scopus 로고    scopus 로고
    • The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation
    • Caretti G, Schiltz RL, Dilworth FJ, Di Padova M, Zhao P, Ogryzko V et al. (2006). The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation. Dev Cell 11: 547-560.
    • (2006) Dev Cell , vol.11 , pp. 547-560
    • Caretti, G.1    Schiltz, R.L.2    Dilworth, F.J.3    Di Padova, M.4    Zhao, P.5    Ogryzko, V.6
  • 14
    • 77957605910 scopus 로고    scopus 로고
    • Phosphorylated p68 RNA helicase activates Snail1 transcription by promoting HDAC1 dissociation from the Snail1 promoter
    • Carter CL, Lin C, Liu CY, Yang L, Liu ZR. (2010). Phosphorylated p68 RNA helicase activates Snail1 transcription by promoting HDAC1 dissociation from the Snail1 promoter. Oncogene 29: 5427-5436.
    • (2010) Oncogene , vol.29 , pp. 5427-5436
    • Carter, C.L.1    Lin, C.2    Liu, C.Y.3    Yang, L.4    Liu, Z.R.5
  • 15
    • 85047696017 scopus 로고    scopus 로고
    • Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours
    • Causevic M, Hislop RG, Kernohan NM, Carey FA, Kay RA, Steele RJ et al. (2001). Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours. Oncogene 20: 7734-7743.
    • (2001) Oncogene , vol.20 , pp. 7734-7743
    • Causevic, M.1    Hislop, R.G.2    Kernohan, N.M.3    Carey, F.A.4    Kay, R.A.5    Steele, R.J.6
  • 16
    • 35648958676 scopus 로고    scopus 로고
    • Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame
    • Chang YF, Chan WK, Imam JS, Wilkinson MF. (2007). Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame. J Biol Chem 282: 29738-29747.
    • (2007) J Biol Chem , vol.282 , pp. 29738-29747
    • Chang, Y.F.1    Chan, W.K.2    Imam, J.S.3    Wilkinson, M.F.4
  • 17
    • 79955567067 scopus 로고    scopus 로고
    • Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells
    • Chen M, Sastry SK, O'Connor KL. (2011). Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells. Am J Physiol Cell Physiol 300: C1155-C1163.
    • (2011) Am J Physiol Cell Physiol , vol.300
    • Chen, M.1    Sastry, S.K.2    O'Connor, K.L.3
  • 18
    • 59449086789 scopus 로고    scopus 로고
    • Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin
    • Chen M, Sinha M, Luxon BA, Bresnick AR, O'Connor KL. (2009). Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin. J Biol Chem 284: 1484-1494.
    • (2009) J Biol Chem , vol.284 , pp. 1484-1494
    • Chen, M.1    Sinha, M.2    Luxon, B.A.3    Bresnick, A.R.4    O'Connor, K.L.5
  • 19
    • 33847776216 scopus 로고    scopus 로고
    • Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: Functional effects of Hsp90 and PARP-1
    • Chen Y, Schnetz MP, Irarrazabal CE, Shen RF, Williams CK, Burg MB et al. (2007). Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1. Am J Physiol Renal Physiol 292: F981-F992.
    • (2007) Am J Physiol Renal Physiol , vol.292
    • Chen, Y.1    Schnetz, M.P.2    Irarrazabal, C.E.3    Shen, R.F.4    Williams, C.K.5    Burg, M.B.6
  • 20
    • 18444365894 scopus 로고    scopus 로고
    • Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis
    • Chuvpilo S, Jankevics E, Tyrsin D, Akimzhanov A, Moroz D, Jha MK et al. (2002). Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis. Immunity 16: 881-895.
    • (2002) Immunity , vol.16 , pp. 881-895
    • Chuvpilo, S.1    Jankevics, E.2    Tyrsin, D.3    Akimzhanov, A.4    Moroz, D.5    Jha, M.K.6
  • 21
    • 54249167990 scopus 로고    scopus 로고
    • The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer
    • Clark EL, Coulson A, Dalgliesh C, Rajan P, Nicol SM, Fleming S et al. (2008). The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer. Cancer Res 68: 7938-7946.
    • (2008) Cancer Res , vol.68 , pp. 7938-7946
    • Clark, E.L.1    Coulson, A.2    Dalgliesh, C.3    Rajan, P.4    Nicol, S.M.5    Fleming, S.6
  • 22
    • 0035001329 scopus 로고    scopus 로고
    • Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP
    • Dahl SC, Handler JS, Kwon HM. (2001). Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP. Am J Physiol Cell Physiol 280: C248-C253.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Dahl, S.C.1    Handler, J.S.2    Kwon, H.M.3
  • 23
    • 0036052587 scopus 로고    scopus 로고
    • Complete cDNA sequence, expression, alternative splicing, and genomic organization of the mouse Nfat5 gene
    • Dalski A, Hebinck A, Winking H, Butzmann U, Schwinger E, Zuhlke C. (2002). Complete cDNA sequence, expression, alternative splicing, and genomic organization of the mouse Nfat5 gene. Cytogenet Genome Res 97: 179-182.
    • (2002) Cytogenet Genome Res , vol.97 , pp. 179-182
    • Dalski, A.1    Hebinck, A.2    Winking, H.3    Butzmann, U.4    Schwinger, E.5    Zuhlke, C.6
  • 24
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
    • David CJ, Manley JL. (2010). Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev 24: 2343-2364.
    • (2010) Genes Dev , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 25
    • 0029860590 scopus 로고    scopus 로고
    • Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours
    • Davies MP, Rudland PS, Robertson L, Parry EW, Jolicoeur P, Barraclough R. (1996). Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. Oncogene 13: 1631-1637.
    • (1996) Oncogene , vol.13 , pp. 1631-1637
    • Davies, M.P.1    Rudland, P.S.2    Robertson, L.3    Parry, E.W.4    Jolicoeur, P.5    Barraclough, R.6
  • 26
    • 77951739131 scopus 로고    scopus 로고
    • Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer
    • Dutertre M, Gratadou L, Dardenne E, Germann S, Samaan S, Lidereau R et al. (2010a). Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer. Cancer Res 70: 3760-3770.
    • (2010) Cancer Res , vol.70 , pp. 3760-3770
    • Dutertre, M.1    Gratadou, L.2    Dardenne, E.3    Germann, S.4    Samaan, S.5    Lidereau, R.6
  • 27
    • 77957307409 scopus 로고    scopus 로고
    • Alternative splicing and breast cancer
    • Dutertre M, Vagner S, Auboeuf D. (2010b). Alternative splicing and breast cancer. RNA Biol 7: 403-411.
    • (2010) RNA Biol , vol.7 , pp. 403-411
    • Dutertre, M.1    Vagner, S.2    Auboeuf, D.3
  • 28
    • 0037154234 scopus 로고    scopus 로고
    • Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration
    • Ferraris JD, Williams CK, Persaud P, Zhang Z, Chen Y, Burg MB. (2002). Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration. Proc Natl Acad Sci USA 99: 739-744.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 739-744
    • Ferraris, J.D.1    Williams, C.K.2    Persaud, P.3    Zhang, Z.4    Chen, Y.5    Burg, M.B.6
  • 29
    • 0028102760 scopus 로고
    • The lipocalin protein family: A role in cell regulation
    • Flower DR. (1994). The lipocalin protein family: a role in cell regulation. FEBS Lett 354: 7-11.
    • (1994) FEBS Lett , vol.354 , pp. 7-11
    • Flower, D.R.1
  • 30
    • 77951028117 scopus 로고    scopus 로고
    • NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene
    • Fougere M, Gaudineau B, Barbier J, Guaddachi F, Feugeas JP, Auboeuf D et al. (2010). NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene. Oncogene 29: 2292-2301.
    • (2010) Oncogene , vol.29 , pp. 2292-2301
    • Fougere, M.1    Gaudineau, B.2    Barbier, J.3    Guaddachi, F.4    Feugeas, J.P.5    Auboeuf, D.6
  • 31
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: Diversity and escape mechanisms
    • Friedl P, Wolf K. (2003). Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3: 362-374.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 32
    • 49349104315 scopus 로고    scopus 로고
    • The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): Novel transcriptional co-regulators
    • Fuller-Pace FV, Ali S. (2008). The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators. Biochem Soc Trans 36: 609-612.
    • (2008) Biochem Soc Trans , vol.36 , pp. 609-612
    • Fuller-Pace, F.V.1    Ali, S.2
  • 33
    • 79952148724 scopus 로고    scopus 로고
    • RNA helicases p68 and p72: Multifunctional proteins with important implications for cancer development
    • Fuller-Pace FV, Moore HC. (2011). RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development. Future Oncol 7: 239-251.
    • (2011) Future Oncol , vol.7 , pp. 239-251
    • Fuller-Pace, F.V.1    Moore, H.C.2
  • 34
    • 77949811343 scopus 로고    scopus 로고
    • Nonsense-mediated RNA decay regulation by cellular stress: Implications for tumorigenesis
    • Gardner LB. (2010). Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis. Mol Cancer Res 8: 295-308.
    • (2010) Mol Cancer Res , vol.8 , pp. 295-308
    • Gardner, L.B.1
  • 36
    • 0344838611 scopus 로고    scopus 로고
    • Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation
    • Guil S, Gattoni R, Carrascal M, Abian J, Stevenin J, Bach-Elias M. (2003). Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation. Mol Cell Biol 23: 2927-2941.
    • (2003) Mol Cell Biol , vol.23 , pp. 2927-2941
    • Guil, S.1    Gattoni, R.2    Carrascal, M.3    Abian, J.4    Stevenin, J.5    Bach-Elias, M.6
  • 37
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 38
    • 21244446530 scopus 로고    scopus 로고
    • The metastasis associated protein S100A4: Role in tumour progression and metastasis
    • Helfman DM, Kim EJ, Lukanidin E, Grigorian M. (2005). The metastasis associated protein S100A4: role in tumour progression and metastasis. Br J Cancer 92: 1955-1958.
    • (2005) Br J Cancer , vol.92 , pp. 1955-1958
    • Helfman, D.M.1    Kim, E.J.2    Lukanidin, E.3    Grigorian, M.4
  • 39
    • 0036318541 scopus 로고    scopus 로고
    • Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72
    • Honig A, Auboeuf D, Parker MM, O'Malley BW, Berget SM. (2002). Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol 22: 5698-5707.
    • (2002) Mol Cell Biol , vol.22 , pp. 5698-5707
    • Honig, A.1    Auboeuf, D.2    Parker, M.M.3    O'Malley, B.W.4    Berget, S.M.5
  • 40
    • 76249133306 scopus 로고    scopus 로고
    • Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP
    • Irarrazabal CE, Gallazzini M, Schnetz MP, Kunin M, Simons BL, Williams CK et al. (2010). Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP. Proc Natl Acad Sci USA 107: 906-911.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 906-911
    • Irarrazabal, C.E.1    Gallazzini, M.2    Schnetz, M.P.3    Kunin, M.4    Simons, B.L.5    Williams, C.K.6
  • 41
    • 34548252476 scopus 로고    scopus 로고
    • SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1
    • Jacobs AM, Nicol SM, Hislop RG, Jaffray EG, Hay RT, Fuller-Pace FV. (2007). SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1. Oncogene 26: 5866-5876.
    • (2007) Oncogene , vol.26 , pp. 5866-5876
    • Jacobs, A.M.1    Nicol, S.M.2    Hislop, R.G.3    Jaffray, E.G.4    Hay, R.T.5    Fuller-Pace, F.V.6
  • 42
    • 77954687609 scopus 로고    scopus 로고
    • Multi-talented DEAD-box proteins and potential tumor promoters: P68 RNA helicase (DDX5) and its paralog, p72 RNA helicase (DDX17)
    • Janknecht R. (2010). Multi-talented DEAD-box proteins and potential tumor promoters: p68 RNA helicase (DDX5) and its paralog, p72 RNA helicase (DDX17). Am J Transl Res 2: 223-234.
    • (2010) Am J Transl Res , vol.2 , pp. 223-234
    • Janknecht, R.1
  • 44
    • 79955379829 scopus 로고    scopus 로고
    • RNA Helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5 splice site
    • Kar A, Fushimi K, Zhou X, Ray P, Shi C, Chen X et al. (2011). RNA Helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5 splice site. Mol Cell Biol 31: 1812-1821.
    • (2011) Mol Cell Biol , vol.31 , pp. 1812-1821
    • Kar, A.1    Fushimi, K.2    Zhou, X.3    Ray, P.4    Shi, C.5    Chen, X.6
  • 45
    • 72249085763 scopus 로고    scopus 로고
    • Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis
    • Leng X, Ding T, Lin H, Wang Y, Hu L, Hu J et al. (2009). Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis. Cancer Res 69: 8579-8584.
    • (2009) Cancer Res , vol.69 , pp. 8579-8584
    • Leng, X.1    Ding, T.2    Lin, H.3    Wang, Y.4    Hu, L.5    Hu, J.6
  • 46
    • 78649641929 scopus 로고    scopus 로고
    • Relationships of lipocalin 2 with breast tumorigenesis and metastasis
    • Leng X, Wu Y, Arlinghaus RB. (2011). Relationships of lipocalin 2 with breast tumorigenesis and metastasis. J Cell Physiol 226: 309-314.
    • (2011) J Cell Physiol , vol.226 , pp. 309-314
    • Leng, X.1    Wu, Y.2    Arlinghaus, R.B.3
  • 47
    • 78649903941 scopus 로고    scopus 로고
    • Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma
    • Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S et al. (2010). Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Mol Cell 40: 841-849.
    • (2010) Mol Cell , vol.40 , pp. 841-849
    • Levy, C.1    Khaled, M.2    Iliopoulos, D.3    Janas, M.M.4    Schubert, S.5    Pinner, S.6
  • 48
    • 0037422575 scopus 로고    scopus 로고
    • Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
    • Lewis BP, Green RE, Brenner SE. (2003). Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc Natl Acad Sci USA 100: 189-192.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 189-192
    • Lewis, B.P.1    Green, R.E.2    Brenner, S.E.3
  • 49
    • 33744931917 scopus 로고    scopus 로고
    • The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA
    • Li ZH, Bresnick AR. (2006). The S100A4 metastasis factor regulates cellular motility via a direct interaction with myosin-IIA. Cancer Res 66: 5173-5180.
    • (2006) Cancer Res , vol.66 , pp. 5173-5180
    • Zh, L.1    Bresnick, A.R.2
  • 50
    • 0034907525 scopus 로고    scopus 로고
    • Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress
    • Lopez-Rodriguez C, Aramburu J, Jin L, Rakeman AS, Michino M, Rao A. (2001). Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress. Immunity 15: 47-58.
    • (2001) Immunity , vol.15 , pp. 47-58
    • Lopez-Rodriguez, C.1    Aramburu, J.2    Jin, L.3    Rakeman, A.S.4    Michino, M.5    Rao, A.6
  • 51
    • 20644466433 scopus 로고    scopus 로고
    • NFAT proteins: Key regulators of T-cell development and function
    • Macian F. (2005). NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 5: 472-484.
    • (2005) Nat Rev Immunol , vol.5 , pp. 472-484
    • MacIan, F.1
  • 52
    • 70350514636 scopus 로고    scopus 로고
    • NFAT proteins: Emerging roles in cancer progression
    • Mancini M, Toker A. (2009). NFAT proteins: emerging roles in cancer progression. Nat Rev Cancer 9: 810-820.
    • (2009) Nat Rev Cancer , vol.9 , pp. 810-820
    • Mancini, M.1    Toker, A.2
  • 54
    • 48149095822 scopus 로고    scopus 로고
    • Alternative splicing resulting in nonsense-mediated mRNA decay: What is the meaning of nonsense?
    • McGlincy NJ, Smith CW. (2008). Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends Biochem Sci 33: 385-393.
    • (2008) Trends Biochem Sci , vol.33 , pp. 385-393
    • McGlincy, N.J.1    Smith, C.W.2
  • 55
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Metivier R, Penot G, Hubner MR, Reid G, Brand H, Kos M et al. (2003). Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115: 751-763.
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1    Penot, G.2    Hubner, M.R.3    Reid, G.4    Brand, H.5    Kos, M.6
  • 56
    • 77957287427 scopus 로고    scopus 로고
    • Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase
    • Mooney SM, Goel A, D'Assoro AB, Salisbury JL, Janknecht R. (2010a). Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase. J Biol Chem 285: 30443-30452.
    • (2010) J Biol Chem , vol.285 , pp. 30443-30452
    • Mooney, S.M.1    Goel, A.2    D'Assoro, A.B.3    Salisbury, J.L.4    Janknecht, R.5
  • 57
    • 73449119972 scopus 로고    scopus 로고
    • Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential
    • Mooney SM, Grande JP, Salisbury JL, Janknecht R. (2010b). Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential. Biochemistry 49: 1-10.
    • (2010) Biochemistry , vol.49 , pp. 1-10
    • Mooney, S.M.1    Grande, J.P.2    Salisbury, J.L.3    Janknecht, R.4
  • 58
    • 78650029658 scopus 로고    scopus 로고
    • The RNA helicase p68 modulates expression and function of the Delta133 isoform(s) of p53, and is inversely associated with Delta133p53 expression in breast cancer
    • Moore HC, Jordan LB, Bray SE, Baker L, Quinlan PR, Purdie CA et al. (2010). The RNA helicase p68 modulates expression and function of the Delta133 isoform(s) of p53, and is inversely associated with Delta133p53 expression in breast cancer. Oncogene 29: 6475-6484.
    • (2010) Oncogene , vol.29 , pp. 6475-6484
    • Moore, H.C.1    Jordan, L.B.2    Bray, S.E.3    Baker, L.4    Quinlan, P.R.5    Purdie, C.A.6
  • 59
    • 77956175013 scopus 로고    scopus 로고
    • NFAT, immunity and cancer: A transcription factor comes of age
    • Muller MR, Rao A. (2010). NFAT, immunity and cancer: a transcription factor comes of age. Nat Rev Immunol 10: 645-656.
    • (2010) Nat Rev Immunol , vol.10 , pp. 645-656
    • Muller, M.R.1    Rao, A.2
  • 60
    • 56049126683 scopus 로고    scopus 로고
    • NMD: Multitasking between mRNA surveillance and modulation of gene expression
    • Neu-Yilik G, Kulozik AE. (2008). NMD: multitasking between mRNA surveillance and modulation of gene expression. Adv Genet 62: 185-243.
    • (2008) Adv Genet , vol.62 , pp. 185-243
    • Neu-Yilik, G.1    Kulozik, A.E.2
  • 61
    • 33846839229 scopus 로고    scopus 로고
    • A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis
    • O'Connor RS, Mills ST, Jones KA, Ho SN, Pavlath GK. (2007). A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis. J Cell Sci 120: 149-159.
    • (2007) J Cell Sci , vol.120 , pp. 149-159
    • O'Connor, R.S.1    Mills, S.T.2    Jones, K.A.3    Ho, S.N.4    Pavlath, G.K.5
  • 62
    • 0037427079 scopus 로고    scopus 로고
    • Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300
    • Rossow KL, Janknecht R. (2003). Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300. Oncogene 22: 151-156.
    • (2003) Oncogene , vol.22 , pp. 151-156
    • Rossow, K.L.1    Janknecht, R.2
  • 63
    • 34548007885 scopus 로고    scopus 로고
    • Involvement of RNA helicases p68 and p72 in colon cancer
    • Shin S, Rossow KL, Grande JP, Janknecht R. (2007). Involvement of RNA helicases p68 and p72 in colon cancer. Cancer Res 67: 7572-7578.
    • (2007) Cancer Res , vol.67 , pp. 7572-7578
    • Shin, S.1    Rossow, K.L.2    Grande, J.P.3    Janknecht, R.4
  • 66
    • 77957767273 scopus 로고    scopus 로고
    • An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition
    • Warzecha CC, Jiang P, Amirikian K, Dittmar KA, Lu H, Shen S et al. (2010). An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. Embo J 29: 3286-3300.
    • (2010) Embo J , vol.29 , pp. 3286-3300
    • Warzecha, C.C.1    Jiang, P.2    Amirikian, K.3    Dittmar, K.A.4    Lu, H.5    Shen, S.6
  • 67
    • 17744373463 scopus 로고    scopus 로고
    • A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA
    • Watanabe M, Yanagisawa J, Kitagawa H, Takeyama K, Ogawa S, Arao Y et al. (2001). A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. Embo J 20: 1341-1352.
    • (2001) Embo J , vol.20 , pp. 1341-1352
    • Watanabe, M.1    Yanagisawa, J.2    Kitagawa, H.3    Takeyama, K.4    Ogawa, S.5    Arao, Y.6
  • 68
    • 26444551757 scopus 로고    scopus 로고
    • The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner
    • Wilson BJ, Bates GJ, Nicol SM, Gregory DJ, Perkins ND, Fuller-Pace FV. (2004). The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner. BMC Mol Biol 5: 11.
    • (2004) BMC Mol Biol , vol.5 , pp. 11
    • Wilson, B.J.1    Bates, G.J.2    Nicol, S.M.3    Gregory, D.J.4    Perkins, N.D.5    Fuller-Pace, F.V.6
  • 69
    • 0000279175 scopus 로고    scopus 로고
    • Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity
    • Woo SK, Dahl SC, Handler JS, Kwon HM. (2000). Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity. Am J Physiol Renal Physiol 278: F1006-F1012.
    • (2000) Am J Physiol Renal Physiol , vol.278
    • Woo, S.K.1    Dahl, S.C.2    Handler, J.S.3    Kwon, H.M.4
  • 70
    • 70450199132 scopus 로고    scopus 로고
    • The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer
    • Wortham NC, Ahamed E, Nicol SM, Thomas RS, Periyasamy M, Jiang J et al. (2009). The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer. Oncogene 28: 4053-4064.
    • (2009) Oncogene , vol.28 , pp. 4053-4064
    • Wortham, N.C.1    Ahamed, E.2    Nicol, S.M.3    Thomas, R.S.4    Periyasamy, M.5    Jiang, J.6
  • 72
    • 21344459251 scopus 로고    scopus 로고
    • Phosphorylations of DEAD box p68 RNA helicase are associated with cancer development and cell proliferation
    • Yang L, Lin C, Liu ZR. (2005). Phosphorylations of DEAD box p68 RNA helicase are associated with cancer development and cell proliferation. Mol Cancer Res 3: 355-363.
    • (2005) Mol Cancer Res , vol.3 , pp. 355-363
    • Yang, L.1    Lin, C.2    Liu, Z.R.3
  • 73
    • 33749078750 scopus 로고    scopus 로고
    • P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin
    • Yang L, Lin C, Liu ZR. (2006). P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin. Cell 127: 139-155.
    • (2006) Cell , vol.127 , pp. 139-155
    • Yang, L.1    Lin, C.2    Liu, Z.R.3
  • 74
    • 34447134154 scopus 로고    scopus 로고
    • Phosphorylation of p68 RNA helicase plays a role in platelet-derived growth factor-induced cell proliferation by up-regulating cyclin D1 and c-Myc expression
    • Yang L, Lin C, Zhao S, Wang H, Liu ZR. (2007). Phosphorylation of p68 RNA helicase plays a role in platelet-derived growth factor-induced cell proliferation by up-regulating cyclin D1 and c-Myc expression. J Biol Chem 282: 16811-16819.
    • (2007) J Biol Chem , vol.282 , pp. 16811-16819
    • Yang, L.1    Lin, C.2    Zhao, S.3    Wang, H.4    Liu, Z.R.5
  • 75
    • 27944446105 scopus 로고    scopus 로고
    • Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT
    • Yoeli-Lerner M, Yiu GK, Rabinovitz I, Erhardt P, Jauliac S, Toker A. (2005). Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. Mol Cell 20: 539-550.
    • (2005) Mol Cell , vol.20 , pp. 539-550
    • Yoeli-Lerner, M.1    Yiu, G.K.2    Rabinovitz, I.3    Erhardt, P.4    Jauliac, S.5    Toker, A.6


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