High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization

Molecular Biology of the Cell

Volumn 22, Issue 5, 2011, Pages 703-714

  Gallazzini, Morgan ^a   Heussler, Gary E ^a,b   Kunin, Margarita ^a,c   Izumi, Yuichiro ^a   Burg, Maurice B ^a,d   Ferraris, Joan D ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b DARTMOUTH COLLEGE   (United States)

^c SHEBA MEDICAL CENTER   (Israel)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLIN DEPENDENT KINASE 5; OSMOTIC RESPONSE ELEMENT BINDING PROTEIN; PROTEIN KINASE FYN; SODIUM CHLORIDE; THREONINE; TONICITY RESPONSIVE ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL PROTECTION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; IN VIVO STUDY; KIDNEY MEDULLA; MALE; MASS SPECTROMETRY; MUTATION; NONHUMAN; OSMOLALITY; PRIORITY JOURNAL; RAT;

ALANINE; ANIMALS; BIOCATALYSIS; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE 5; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; KIDNEY MEDULLA; MUTATION; OSMOLAR CONCENTRATION; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-FYN; RATS; SODIUM CHLORIDE; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 79952342170     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E10-08-0681     Document Type: Article

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