Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C-γ1 to activation of the osmoprotective transcription factor NFAT5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 29, 2011, Pages 12155-12160

  Zhou, Xiaoming ^a   Izumi, Yuichiro ^b   Burg, Maurice B ^b   Ferraris, Joan D ^b  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

MAPK; Osmotic stress

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OSMOSENSING SCAFFOLD FOR MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; PHOSPHOLIPASE C GAMMA1; RAC1 PROTEIN; SCAFFOLD PROTEIN; SMALL INTERFERING RNA; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYST; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; FIBROBLAST; GENETIC TRANSFECTION; MOLECULAR SENSOR; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSACTIVATION; TRANSCRIPTION INITIATION;

ANIMALS; BLOTTING, WESTERN; CELL LINE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUCIFERASES; MAP KINASE KINASE 3; MICE; MICROFILAMENT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 14; NEUROPEPTIDES; PHOSPHOLIPASE C GAMMA; RAC GTP-BINDING PROTEINS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 79961039250     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1108107108     Document Type: Article

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