메뉴 건너뛰기




Volumn 118, Issue , 2013, Pages 129-158

Autoimmunity in Rheumatoid Arthritis: Citrulline Immunity and Beyond

Author keywords

Arthritis; Autoimmune disease; Citrullination; Gene environment interactions; Tolerance

Indexed keywords

ALPHA ENOLASE; AUTOANTIGEN; COAL; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; HLA ANTIGEN CLASS 2; HLA DP ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; RHEUMATOID FACTOR; SILICON DIOXIDE;

EID: 84878050627     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/B978-0-12-407708-9.00003-0     Document Type: Chapter
Times cited : (35)

References (142)
  • 1
    • 65949083562 scopus 로고    scopus 로고
    • The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis
    • Ahlqvist E., Hultqvist M., Holmdahl R. The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis. Arthritis Research & Therapy 2009, 11(3):226.
    • (2009) Arthritis Research & Therapy , vol.11 , Issue.3 , pp. 226
    • Ahlqvist, E.1    Hultqvist, M.2    Holmdahl, R.3
  • 2
    • 77956055481 scopus 로고    scopus 로고
    • 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative
    • Aletaha D., Neogi T., Silman A.J., Funovits J., Felson D.T., Bingham C.O., et al. 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis and Rheumatism 2010, 62(9):2569-2581.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.9 , pp. 2569-2581
    • Aletaha, D.1    Neogi, T.2    Silman, A.J.3    Funovits, J.4    Felson, D.T.5    Bingham, C.O.6
  • 3
    • 84877587255 scopus 로고    scopus 로고
    • Monoclonal IgG antibody generation from joint-derived B cells of Ra patients-Strong bias towards autoantigen recognition
    • Amara K., Steen J., Murray F., Morbach H., Fernandez-Rodriguez B.M., Snir O. Monoclonal IgG antibody generation from joint-derived B cells of Ra patients-Strong bias towards autoantigen recognition. Journal of Experimental Medicine 2013, 210(3):445-455.
    • (2013) Journal of Experimental Medicine , vol.210 , Issue.3 , pp. 445-455
    • Amara, K.1    Steen, J.2    Murray, F.3    Morbach, H.4    Fernandez-Rodriguez, B.M.5    Snir, O.6
  • 4
    • 77952920098 scopus 로고    scopus 로고
    • Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation
    • Andrade F., Darrah E., Gucek M., Cole R.N., Rosen A., Zhu X. Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis and Rheumatism 2010, 62(6):1630-1640.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.6 , pp. 1630-1640
    • Andrade, F.1    Darrah, E.2    Gucek, M.3    Cole, R.N.4    Rosen, A.5    Zhu, X.6
  • 5
    • 65449176044 scopus 로고    scopus 로고
    • Cutting edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling
    • Arechiga A.F., Habib T., He Y., Zhang X., Zhang Z.Y., Funk A., et al. Cutting edge: The PTPN22 allelic variant associated with autoimmunity impairs B cell signaling. Journal of Immunology 2009, 182(6):3343-3347.
    • (2009) Journal of Immunology , vol.182 , Issue.6 , pp. 3343-3347
    • Arechiga, A.F.1    Habib, T.2    He, Y.3    Zhang, X.4    Zhang, Z.Y.5    Funk, A.6
  • 6
    • 84867081740 scopus 로고    scopus 로고
    • Pre-rheumatoid arthritis: Predisposition and transition to clinical synovitis
    • Arend W.P., Firestein G.S. Pre-rheumatoid arthritis: Predisposition and transition to clinical synovitis. Nature Reviews. Rheumatology 2012, 8(10):573-586.
    • (2012) Nature Reviews. Rheumatology , vol.8 , Issue.10 , pp. 573-586
    • Arend, W.P.1    Firestein, G.S.2
  • 7
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett F.C., Edworthy S.M., Bloch D.A., McShane D.J., Fries J.F., Cooper N.S., et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis and Rheumatism 1988, 31(3):315-324.
    • (1988) Arthritis and Rheumatism , vol.31 , Issue.3 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3    McShane, D.J.4    Fries, J.F.5    Cooper, N.S.6
  • 9
    • 80055062109 scopus 로고    scopus 로고
    • Direct ex-vivo evaluation of pneumococcal specific T-cells in healthy adults
    • Aslam A., Chapel H., Ogg G. Direct ex-vivo evaluation of pneumococcal specific T-cells in healthy adults. PLoS One 2011, 6(10):e25367.
    • (2011) PLoS One , vol.6 , Issue.10
    • Aslam, A.1    Chapel, H.2    Ogg, G.3
  • 10
    • 27744514543 scopus 로고    scopus 로고
    • Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen
    • Auger I., Sebbag M., Vincent C., Balandraud N., Guis S., Nogueira L., et al. Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrinogen. Arthritis and Rheumatism 2005, 52(11):3424-3432.
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.11 , pp. 3424-3432
    • Auger, I.1    Sebbag, M.2    Vincent, C.3    Balandraud, N.4    Guis, S.5    Nogueira, L.6
  • 11
    • 81055146927 scopus 로고    scopus 로고
    • Tobacco smoke augments Porphyromonas gingivalis-Streptococcus gordonii biofilm formation
    • Bagaitkar J., Daep C.A., Patel C.K., Renaud D.E., Demuth D.R., Scott D.A. Tobacco smoke augments Porphyromonas gingivalis-Streptococcus gordonii biofilm formation. PLoS One 2011, 6(11):e27386. 10.1371/journal.pone.0027386.
    • (2011) PLoS One , vol.6 , Issue.11
    • Bagaitkar, J.1    Daep, C.A.2    Patel, C.K.3    Renaud, D.E.4    Demuth, D.R.5    Scott, D.A.6
  • 12
    • 0031886916 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial
    • Erratum in: Arthritis Rheum 1998 May;41(5):938
    • Barnett M.L., Kremer J.M., St Clair E.W., Clegg D.O., Furst D., Weisman M., et al. Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial. Arthritis and Rheumatism 1998, 41(2):290-297. Erratum in: Arthritis Rheum 1998 May;41(5):938.
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.2 , pp. 290-297
    • Barnett, M.L.1    Kremer, J.M.2    St Clair, E.W.3    Clegg, D.O.4    Furst, D.5    Weisman, M.6
  • 13
    • 46249101392 scopus 로고    scopus 로고
    • Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility
    • Barton A., Thomson W., Ke X., Eyre S., Hinks A., Bowes J., et al. Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Human Molecular Genetics 2008, 17(15):2274-2279.
    • (2008) Human Molecular Genetics , vol.17 , Issue.15 , pp. 2274-2279
    • Barton, A.1    Thomson, W.2    Ke, X.3    Eyre, S.4    Hinks, A.5    Bowes, J.6
  • 14
    • 79961024145 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis: What have we learned?
    • Bax M., van Heemst J., Huizinga T.W., Toes R.E. Genetics of rheumatoid arthritis: What have we learned?. Immunogenetics 2011, 63(8):459-466.
    • (2011) Immunogenetics , vol.63 , Issue.8 , pp. 459-466
    • Bax, M.1    van Heemst, J.2    Huizinga, T.W.3    Toes, R.E.4
  • 15
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich A.B., Carlton V.E., Honigberg L.A., Schrodi S.J., Chokkalingam A.P., Alexander H.C., et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. American Journal of Human Genetics 2004, 75(2):330-337.
    • (2004) American Journal of Human Genetics , vol.75 , Issue.2 , pp. 330-337
    • Begovich, A.B.1    Carlton, V.E.2    Honigberg, L.A.3    Schrodi, S.J.4    Chokkalingam, A.P.5    Alexander, H.C.6
  • 17
    • 0023187442 scopus 로고
    • The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
    • Bjorkman P.J., Saper M.A., Samraoui B., Bennett W.S., Strominger J.L., Wiley D.C. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 1987, 329(6139):512-518.
    • (1987) Nature , vol.329 , Issue.6139 , pp. 512-518
    • Bjorkman, P.J.1    Saper, M.A.2    Samraoui, B.3    Bennett, W.S.4    Strominger, J.L.5    Wiley, D.C.6
  • 18
    • 84875750538 scopus 로고    scopus 로고
    • Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis
    • Jan 10. [Epub ahead of print]
    • Brink M., Hansson M., Mathsson L., Jakobsson P.J., Holmdahl R., Hallmans G., et al. Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis. Arthritis and Rheumatism 2013, Jan 10. [Epub ahead of print].
    • (2013) Arthritis and Rheumatism
    • Brink, M.1    Hansson, M.2    Mathsson, L.3    Jakobsson, P.J.4    Holmdahl, R.5    Hallmans, G.6
  • 19
    • 31044442026 scopus 로고    scopus 로고
    • Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis
    • Burkhardt H., Hüffmeier U., Spriewald B., Böhm B., Rau R., Kallert S., et al. Association between protein tyrosine phosphatase 22 variant R620W in conjunction with the HLA-DRB1 shared epitope and humoral autoimmunity to an immunodominant epitope of cartilage-specific type II collagen in early rheumatoid arthritis. Arthritis and Rheumatism 2006, 54(1):82-89.
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.1 , pp. 82-89
    • Burkhardt, H.1    Hüffmeier, U.2    Spriewald, B.3    Böhm, B.4    Rau, R.5    Kallert, S.6
  • 20
    • 67650021589 scopus 로고    scopus 로고
    • Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis
    • Cantaert T., Brouard S., Thurlings R.M., Pallier A., Salinas G.F., Braud C., et al. Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis. Arthritis and Rheumatism 2009, 60(7):1944-1956.
    • (2009) Arthritis and Rheumatism , vol.60 , Issue.7 , pp. 1944-1956
    • Cantaert, T.1    Brouard, S.2    Thurlings, R.M.3    Pallier, A.4    Salinas, G.F.5    Braud, C.6
  • 21
    • 44949146901 scopus 로고
    • Rheumatoid disease and pneumoconiosis (Caplan's syndrome)
    • Caplan A. Rheumatoid disease and pneumoconiosis (Caplan's syndrome). Proceedings of the Royal Society of Medicine 1959, 52:1111-1113.
    • (1959) Proceedings of the Royal Society of Medicine , vol.52 , pp. 1111-1113
    • Caplan, A.1
  • 24
    • 17044409168 scopus 로고    scopus 로고
    • Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides
    • Chapuy-Regaud S., Sebbag M., Baeten D., Clavel C., Foulquier C., De Keyser F., et al. Fibrin deimination in synovial tissue is not specific for rheumatoid arthritis but commonly occurs during synovitides. Journal of Immunology 2005, 174(8):5057-5064.
    • (2005) Journal of Immunology , vol.174 , Issue.8 , pp. 5057-5064
    • Chapuy-Regaud, S.1    Sebbag, M.2    Baeten, D.3    Clavel, C.4    Foulquier, C.5    De Keyser, F.6
  • 25
    • 66149114010 scopus 로고    scopus 로고
    • Comparison of threshold cutpoints and continuous measures of anti-cyclic citrullinated peptide antibodies in predicting future rheumatoid arthritis
    • Chibnik L.B., Mandl L.A., Costenbader K.H., Schur P.H., Karlson E.W. Comparison of threshold cutpoints and continuous measures of anti-cyclic citrullinated peptide antibodies in predicting future rheumatoid arthritis. Journal of Rheumatology 2009, 36(4):706-711.
    • (2009) Journal of Rheumatology , vol.36 , Issue.4 , pp. 706-711
    • Chibnik, L.B.1    Mandl, L.A.2    Costenbader, K.H.3    Schur, P.H.4    Karlson, E.W.5
  • 26
    • 79958838779 scopus 로고    scopus 로고
    • Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)-positive rheumatoid arthritis in three Asian ethnic groups
    • Chun-Lai T., Padyukov L., Dhaliwal J.S., Lundström E., Yahya A., Muhamad N.A., et al. Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)-positive rheumatoid arthritis in three Asian ethnic groups. PLoS One 2011, 6(6):e21069.
    • (2011) PLoS One , vol.6 , Issue.6
    • Chun-Lai, T.1    Padyukov, L.2    Dhaliwal, J.S.3    Lundström, E.4    Yahya, A.5    Muhamad, N.A.6
  • 27
    • 28444479823 scopus 로고    scopus 로고
    • Current understanding of the genetic aetiology of rheumatoid arthritis and likely future developments
    • Criswell L.A., Gregersen P.K. Current understanding of the genetic aetiology of rheumatoid arthritis and likely future developments. Rheumatology (Oxford, England) 2005, 44(Suppl. 4):iv9-iv13.
    • (2005) Rheumatology (Oxford, England) , vol.44 , Issue.SUPPL. 4
    • Criswell, L.A.1    Gregersen, P.K.2
  • 29
    • 84864545087 scopus 로고    scopus 로고
    • Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
    • Dinarello C.A., Simon A., van der Meer J.W. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nature Reviews. Drug Discovery 2012, 11(8):633-652.
    • (2012) Nature Reviews. Drug Discovery , vol.11 , Issue.8 , pp. 633-652
    • Dinarello, C.A.1    Simon, A.2    van der Meer, J.W.3
  • 30
    • 58249097071 scopus 로고    scopus 로고
    • Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region
    • Erratum in: Arthritis Rheum. 2009 Apr;60(4):1200
    • Ding B., Padyukov L., Lundström E., Seielstad M., Plenge R.M., Oksenberg J.R., et al. Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis and Rheumatism 2009, 60(1):30-38. Erratum in: Arthritis Rheum. 2009 Apr;60(4):1200.
    • (2009) Arthritis and Rheumatism , vol.60 , Issue.1 , pp. 30-38
    • Ding, B.1    Padyukov, L.2    Lundström, E.3    Seielstad, M.4    Plenge, R.M.5    Oksenberg, J.R.6
  • 31
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C., Pétrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320(5876):674-677.
    • (2008) Science , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Pétrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 32
    • 31144450506 scopus 로고    scopus 로고
    • Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules
    • Dzhambazov B., Nandakumar K.S., Kihlberg J., Fugger L., Holmdahl R., Vestberg M. Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. Journal of Immunology 2006, 176(3):1525-1533.
    • (2006) Journal of Immunology , vol.176 , Issue.3 , pp. 1525-1533
    • Dzhambazov, B.1    Nandakumar, K.S.2    Kihlberg, J.3    Fugger, L.4    Holmdahl, R.5    Vestberg, M.6
  • 33
    • 84861809361 scopus 로고    scopus 로고
    • Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients
    • El-Gabalawy H.S., Robinson D.B., Smolik I., Hart D., Elias B., Wong K., et al. Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients. Arthritis and Rheumatism 2012, 64(6):1720-1729.
    • (2012) Arthritis and Rheumatism , vol.64 , Issue.6 , pp. 1720-1729
    • El-Gabalawy, H.S.1    Robinson, D.B.2    Smolik, I.3    Hart, D.4    Elias, B.5    Wong, K.6
  • 34
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott M.J., Maini R.N., Feldmann M., Kalden J.R., Antoni C., Smolen J.S., Leeb B., et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994, 344(8930):1105-1110.
    • (1994) Lancet , vol.344 , Issue.8930 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Kalden, J.R.4    Antoni, C.5    Smolen, J.S.6    Leeb, B.7
  • 35
    • 84870531924 scopus 로고    scopus 로고
    • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
    • Eyre S., Bowes J., Diogo D., Lee A., Barton A., Martin P., et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nature Genetics 2012, 44(12):1336-1340.
    • (2012) Nature Genetics , vol.44 , Issue.12 , pp. 1336-1340
    • Eyre, S.1    Bowes, J.2    Diogo, D.3    Lee, A.4    Barton, A.5    Martin, P.6
  • 36
    • 0032960781 scopus 로고    scopus 로고
    • The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues
    • Girbal-Neuhauser E., Durieux J.J., Arnaud M., Dalbon P., Sebbag M., Vincent C., et al. The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues. Journal of Immunology 1999, 162(1):585-594.
    • (1999) Journal of Immunology , vol.162 , Issue.1 , pp. 585-594
    • Girbal-Neuhauser, E.1    Durieux, J.J.2    Arnaud, M.3    Dalbon, P.4    Sebbag, M.5    Vincent, C.6
  • 37
    • 80052168618 scopus 로고    scopus 로고
    • Dimeric MHC-peptides inserted into an immunoglobulin scaffold as new immunotherapeutic agents
    • Goldberg B., Bona C. Dimeric MHC-peptides inserted into an immunoglobulin scaffold as new immunotherapeutic agents. Journal of Cellular and Molecular Medicine 2011, 15(9):1822-1832.
    • (2011) Journal of Cellular and Molecular Medicine , vol.15 , Issue.9 , pp. 1822-1832
    • Goldberg, B.1    Bona, C.2
  • 38
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • Review
    • Gregersen P.K., Silver J., Winchester R.J. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis and Rheumatism 1987, 30(11):1205-1213. Review.
    • (1987) Arthritis and Rheumatism , vol.30 , Issue.11 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 40
    • 84860561645 scopus 로고    scopus 로고
    • Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
    • Harre U., Georgess D., Bang H., Bozec A., Axmann R., Ossipova E., et al. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. The Journal of Clinical Investigation 2012, 122(5):1791-1802.
    • (2012) The Journal of Clinical Investigation , vol.122 , Issue.5 , pp. 1791-1802
    • Harre, U.1    Georgess, D.2    Bang, H.3    Bozec, A.4    Axmann, R.5    Ossipova, E.6
  • 41
    • 47249163722 scopus 로고    scopus 로고
    • Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis
    • Harris M.L., Darrah E., Lam G.K., Bartlett S.J., Giles J.T., Grant A.V., et al. Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis. Arthritis and Rheumatism 2008, 58(7):1958-1967.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.7 , pp. 1958-1967
    • Harris, M.L.1    Darrah, E.2    Lam, G.K.3    Bartlett, S.J.4    Giles, J.T.5    Grant, A.V.6
  • 42
    • 78149487035 scopus 로고    scopus 로고
    • Generation and characterization of therapeutic tolerogenic dendritic cells for rheumatoid arthritis
    • Harry R.A., Anderson A.E., Isaacs J.D., Hilkens C.M. Generation and characterization of therapeutic tolerogenic dendritic cells for rheumatoid arthritis. Annals of the Rheumatic Diseases 2010, 69(11):2042-2050.
    • (2010) Annals of the Rheumatic Diseases , vol.69 , Issue.11 , pp. 2042-2050
    • Harry, R.A.1    Anderson, A.E.2    Isaacs, J.D.3    Hilkens, C.M.4
  • 43
    • 84877596285 scopus 로고    scopus 로고
    • Ambient air pollution exposures and risk of rheumatoid arthritis: Results from the Swedish EIRA case-control study
    • Jul 24 [Epub ahead of print]
    • Hart J.E., Källberg H., Laden F., Bellander T., Costenbader K.H., Holmqvist M., et al. Ambient air pollution exposures and risk of rheumatoid arthritis: Results from the Swedish EIRA case-control study. Annals of the Rheumatic Diseases 2012, Jul 24 [Epub ahead of print].
    • (2012) Annals of the Rheumatic Diseases
    • Hart, J.E.1    Källberg, H.2    Laden, F.3    Bellander, T.4    Costenbader, K.H.5    Holmqvist, M.6
  • 45
    • 42249098465 scopus 로고    scopus 로고
    • Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice
    • Hill J.A., Bell D.A., Brintnell W., Yue D., Wehrli B., Jevnikar A.M., et al. Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice. The Journal of Experimental Medicine 2008, 205(4):967-979.
    • (2008) The Journal of Experimental Medicine , vol.205 , Issue.4 , pp. 967-979
    • Hill, J.A.1    Bell, D.A.2    Brintnell, W.3    Yue, D.4    Wehrli, B.5    Jevnikar, A.M.6
  • 47
    • 38849099736 scopus 로고    scopus 로고
    • The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis
    • Hoffmann M.H., Tuncel J., Skriner K., Tohidast-Akrad M., Türk B., Pinol-Roma S., et al. The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis. Journal of Immunology 2007, 179(11):7568-7576.
    • (2007) Journal of Immunology , vol.179 , Issue.11 , pp. 7568-7576
    • Hoffmann, M.H.1    Tuncel, J.2    Skriner, K.3    Tohidast-Akrad, M.4    Türk, B.5    Pinol-Roma, S.6
  • 48
    • 31544452514 scopus 로고    scopus 로고
    • Dissection of the genetic complexity of arthritis using animal models
    • Holmdahl R. Dissection of the genetic complexity of arthritis using animal models. Immunology Letters 2006, 103(2):86-91.
    • (2006) Immunology Letters , vol.103 , Issue.2 , pp. 86-91
    • Holmdahl, R.1
  • 49
    • 0034677123 scopus 로고    scopus 로고
    • Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice
    • Horai R., Saijo S., Tanioka H., Nakae S., Sudo K., Okahara A., et al. Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice. The Journal of Experimental Medicine 2000, 191(2):313-320.
    • (2000) The Journal of Experimental Medicine , vol.191 , Issue.2 , pp. 313-320
    • Horai, R.1    Saijo, S.2    Tanioka, H.3    Nakae, S.4    Sudo, K.5    Okahara, A.6
  • 50
    • 84877631947 scopus 로고    scopus 로고
    • Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA)
    • Hughes-Austin J.M., Deane K.D., Derber L.A., Kolfenbach J.R., Zerbe G.O., Sokolove J., et al. Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA). Annals of the Rheumatic Diseases 2012.
    • (2012) Annals of the Rheumatic Diseases
    • Hughes-Austin, J.M.1    Deane, K.D.2    Derber, L.A.3    Kolfenbach, J.R.4    Zerbe, G.O.5    Sokolove, J.6
  • 51
    • 27744550413 scopus 로고    scopus 로고
    • Refining the complex rheumatoid arthritis. Phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins
    • Huizinga T.W., Amos C.I., van der Helm-van Mil A.H., Chen W., van Gaalen F.A., Jawaheer D., et al. Refining the complex rheumatoid arthritis. Phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis and Rheumatism 2005, 52(11):3433-3438.
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.11 , pp. 3433-3438
    • Huizinga, T.W.1    Amos, C.I.2    van der Helm-van Mil, A.H.3    Chen, W.4    van Gaalen, F.A.5    Jawaheer, D.6
  • 52
    • 78650632503 scopus 로고    scopus 로고
    • Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities
    • Ioan-Facsinay A., el-Bannoudi H., Scherer H.U., van der Woude D., Ménard H.A., Lora M., et al. Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities. Annals of the Rheumatic Diseases 2011, 70(1):188-193.
    • (2011) Annals of the Rheumatic Diseases , vol.70 , Issue.1 , pp. 188-193
    • Ioan-Facsinay, A.1    el-Bannoudi, H.2    Scherer, H.U.3    van der Woude, D.4    Ménard, H.A.5    Lora, M.6
  • 53
    • 77957687497 scopus 로고    scopus 로고
    • HLA-DR 1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets
    • James E.A., Moustakas A.K., Bui J., Papadopoulos G.K., Bondinas G., Buckner J.H., Kwok W.W. HLA-DR 1001 presents "altered-self" peptides derived from joint-associated proteins by accepting citrulline in three of its binding pockets. Arthritis and Rheumatism 2010, 62(10):2909-2918.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.10 , pp. 2909-2918
    • James, E.A.1    Moustakas, A.K.2    Bui, J.3    Papadopoulos, G.K.4    Bondinas, G.5    Buckner, J.H.6    Kwok, W.W.7
  • 54
    • 0019486851 scopus 로고
    • Rheumatoid arthritis: A disease of T-lymphocyte/macrophage immunoregulation
    • Janossy G., Panayi G., Duke O., Bofill M., Poulter L.W., Goldstein G. Rheumatoid arthritis: A disease of T-lymphocyte/macrophage immunoregulation. Lancet 1981, 2(8251):839-842.
    • (1981) Lancet , vol.2 , Issue.8251 , pp. 839-842
    • Janossy, G.1    Panayi, G.2    Duke, O.3    Bofill, M.4    Poulter, L.W.5    Goldstein, G.6
  • 55
    • 79951515816 scopus 로고    scopus 로고
    • Smoking is a major preventable risk factor for rheumatoid arthritis: Estimations of risks after various exposures to cigarette smoke
    • Kallberg H., Ding B., Padyukov L., Bengtsson C., Rönnelid J., Klareskog L., et al. Smoking is a major preventable risk factor for rheumatoid arthritis: Estimations of risks after various exposures to cigarette smoke. Annals of the Rheumatic Diseases 2010, 70(3):508-511.
    • (2010) Annals of the Rheumatic Diseases , vol.70 , Issue.3 , pp. 508-511
    • Kallberg, H.1    Ding, B.2    Padyukov, L.3    Bengtsson, C.4    Rönnelid, J.5    Klareskog, L.6
  • 57
    • 73449089454 scopus 로고    scopus 로고
    • Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis
    • Karlson E.W., Chang S.C., Cui J., Chibnik L.B., Fraser P.A., De Vivo I., et al. Gene-environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis. Annals of the Rheumatic Diseases 2010, 69(1):54-60.
    • (2010) Annals of the Rheumatic Diseases , vol.69 , Issue.1 , pp. 54-60
    • Karlson, E.W.1    Chang, S.C.2    Cui, J.3    Chibnik, L.B.4    Fraser, P.A.5    De Vivo, I.6
  • 58
    • 0033056367 scopus 로고    scopus 로고
    • A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice
    • Kassiotis G., Bauer J., Akassoglou K., Lassmann H., Kollias G., Probert L. A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice. European Journal of Immunology 1999, 29(3):912-917.
    • (1999) European Journal of Immunology , vol.29 , Issue.3 , pp. 912-917
    • Kassiotis, G.1    Bauer, J.2    Akassoglou, K.3    Lassmann, H.4    Kollias, G.5    Probert, L.6
  • 59
    • 82455163717 scopus 로고    scopus 로고
    • Immunization with Porphyromonas gingivalis enolase induces autoimmunity to mammalian α-enolase and arthritis in DR4-IE-transgenic mice
    • Kinloch A.J., Alzabin S., Brintnell W., Wilson E., Barra L., Wegner N., et al. Immunization with Porphyromonas gingivalis enolase induces autoimmunity to mammalian α-enolase and arthritis in DR4-IE-transgenic mice. Arthritis and Rheumatism 2011, 63(12):3818-3823.
    • (2011) Arthritis and Rheumatism , vol.63 , Issue.12 , pp. 3818-3823
    • Kinloch, A.J.1    Alzabin, S.2    Brintnell, W.3    Wilson, E.4    Barra, L.5    Wegner, N.6
  • 61
    • 79953162113 scopus 로고    scopus 로고
    • Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis
    • Klareskog L., Malmström V., Lundberg K., Padyukov L., Alfredsson L. Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis. Seminars in Immunology 2011, 23(2):92-98.
    • (2011) Seminars in Immunology , vol.23 , Issue.2 , pp. 92-98
    • Klareskog, L.1    Malmström, V.2    Lundberg, K.3    Padyukov, L.4    Alfredsson, L.5
  • 63
    • 31044445025 scopus 로고    scopus 로고
    • A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination
    • Klareskog L., Stolt P., Lundberg K., Källberg H., Bengtsson C., Grunewald J., et al. A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. Arthritis and Rheumatism 2006, 54(1):38-46.
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.1 , pp. 38-46
    • Klareskog, L.1    Stolt, P.2    Lundberg, K.3    Källberg, H.4    Bengtsson, C.5    Grunewald, J.6
  • 64
    • 0026328172 scopus 로고
    • Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement
    • Kleinau S., Erlandsson H., Holmdahl R., Klareskog L. Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement. Journal of Autoimmunity 1991, 4(6):871-880.
    • (1991) Journal of Autoimmunity , vol.4 , Issue.6 , pp. 871-880
    • Kleinau, S.1    Erlandsson, H.2    Holmdahl, R.3    Klareskog, L.4
  • 67
    • 0026681481 scopus 로고
    • Immunopathology of rheumatoid arthritis. Antikeratin antibodies precede the clinical disease
    • Kurki P., Aho K., Palosuo T., Heliövaara M. Immunopathology of rheumatoid arthritis. Antikeratin antibodies precede the clinical disease. Arthritis and Rheumatism 1992, 35(8):914-917.
    • (1992) Arthritis and Rheumatism , vol.35 , Issue.8 , pp. 914-917
    • Kurki, P.1    Aho, K.2    Palosuo, T.3    Heliövaara, M.4
  • 68
    • 44649135985 scopus 로고    scopus 로고
    • Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus
    • Lee H.S., Lee A.T., Criswell L.A., Seldin M.F., Amos C.I., Carulli J.P., et al. Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. Molecular Medicine 2008, 14(5-6):293-300.
    • (2008) Molecular Medicine , vol.14 , Issue.5-6 , pp. 293-300
    • Lee, H.S.1    Lee, A.T.2    Criswell, L.A.3    Seldin, M.F.4    Amos, C.I.5    Carulli, J.P.6
  • 69
    • 60749130247 scopus 로고    scopus 로고
    • Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects
    • Long S.A., Walker M.R., Rieck M., James E., Kwok W.W., Sanda S., et al. Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. European Journal of Immunology 2009, 39(2):612-620.
    • (2009) European Journal of Immunology , vol.39 , Issue.2 , pp. 612-620
    • Long, S.A.1    Walker, M.R.2    Rieck, M.3    James, E.4    Kwok, W.W.5    Sanda, S.6
  • 70
    • 77951726471 scopus 로고    scopus 로고
    • Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production
    • Lu M.C., Lai N.S., Yu H.C., Huang H.B., Hsieh S.C., Yu C.L. Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production. Arthritis and Rheumatism 2010, 62(5):1213-1223.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.5 , pp. 1213-1223
    • Lu, M.C.1    Lai, N.S.2    Yu, H.C.3    Huang, H.B.4    Hsieh, S.C.5    Yu, C.L.6
  • 72
    • 84875930018 scopus 로고    scopus 로고
    • Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile
    • Sep 8. [Epub ahead of print]
    • Lundberg K., Bengtsson C., Kharlamova N., Reed E., Jiang X., Kallberg H., et al. Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile. Annals of the Rheumatic Diseases 2012, Sep 8. [Epub ahead of print].
    • (2012) Annals of the Rheumatic Diseases
    • Lundberg, K.1    Bengtsson, C.2    Kharlamova, N.3    Reed, E.4    Jiang, X.5    Kallberg, H.6
  • 73
    • 54949091137 scopus 로고    scopus 로고
    • Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase
    • Lundberg K., Kinloch A., Fisher B.A., Wegner N., Wait R., Charles P., et al. Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase. Arthritis and Rheumatism 2008, 58(10):3009-3019.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.10 , pp. 3009-3019
    • Lundberg, K.1    Kinloch, A.2    Fisher, B.A.3    Wegner, N.4    Wait, R.5    Charles, P.6
  • 74
    • 27744515706 scopus 로고    scopus 로고
    • Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity
    • Lundberg K., Nijenhuis S., Vossenaar E.R., Palmblad K., van Venrooij W.J., Klareskog L., et al. Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity. Arthritis Research & Therapy 2005, 7(3):R458-R467.
    • (2005) Arthritis Research & Therapy , vol.7 , Issue.3
    • Lundberg, K.1    Nijenhuis, S.2    Vossenaar, E.R.3    Palmblad, K.4    van Venrooij, W.J.5    Klareskog, L.6
  • 76
    • 53049098138 scopus 로고    scopus 로고
    • Antigen-specific therapies in MS-Current concepts and novel approaches
    • Lutterotti A., Sospedra M., Martin R. Antigen-specific therapies in MS-Current concepts and novel approaches. Journal of the Neurological Sciences 2008, 274(1-2):18-22.
    • (2008) Journal of the Neurological Sciences , vol.274 , Issue.1-2 , pp. 18-22
    • Lutterotti, A.1    Sospedra, M.2    Martin, R.3
  • 77
    • 70649108632 scopus 로고    scopus 로고
    • Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis
    • Mahdi H., Fisher B.A., Källberg H., Plant D., Malmström V., Rönnelid J., et al. Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis. Nature Genetics 2009, 41(12):1319-1324.
    • (2009) Nature Genetics , vol.41 , Issue.12 , pp. 1319-1324
    • Mahdi, H.1    Fisher, B.A.2    Källberg, H.3    Plant, D.4    Malmström, V.5    Rönnelid, J.6
  • 78
    • 53149103590 scopus 로고    scopus 로고
    • Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
    • Makrygiannakis D., Hermansson M., Ulfgren A.K., Nicholas A.P., Zendman A.J., Eklund A., et al. Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Annals of the Rheumatic Diseases 2008, 67(10):1488-1492.
    • (2008) Annals of the Rheumatic Diseases , vol.67 , Issue.10 , pp. 1488-1492
    • Makrygiannakis, D.1    Hermansson, M.2    Ulfgren, A.K.3    Nicholas, A.P.4    Zendman, A.J.5    Eklund, A.6
  • 80
    • 0037388277 scopus 로고    scopus 로고
    • Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders
    • Matsumoto I., Lee D.M., Goldbach-Mansky R., Sumida T., Hitchon C.A., Schur P.H., et al. Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis and Rheumatism 2003, 48(4):944-954.
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.4 , pp. 944-954
    • Matsumoto, I.1    Lee, D.M.2    Goldbach-Mansky, R.3    Sumida, T.4    Hitchon, C.A.5    Schur, P.H.6
  • 81
    • 0033607499 scopus 로고    scopus 로고
    • Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
    • Matsumoto I., Staub A., Benoist C., Mathis D. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science 1999, 286(5445):1732-1735.
    • (1999) Science , vol.286 , Issue.5445 , pp. 1732-1735
    • Matsumoto, I.1    Staub, A.2    Benoist, C.3    Mathis, D.4
  • 83
    • 80052376347 scopus 로고    scopus 로고
    • The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
    • Menard L., Saadoun D., Isnardi I., Ng Y.S., Meyers G., Massad C., et al. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. The Journal of Clinical Investigation 2011, 121(9):3635-3644.
    • (2011) The Journal of Clinical Investigation , vol.121 , Issue.9 , pp. 3635-3644
    • Menard, L.1    Saadoun, D.2    Isnardi, I.3    Ng, Y.S.4    Meyers, G.5    Massad, C.6
  • 84
    • 84867164849 scopus 로고    scopus 로고
    • Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis
    • Mikuls T.R., Thiele G.M., Deane K.D., Payne J.B., O'Dell J.R., Yu F., et al. Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis. Arthritis and Rheumatism 2012, 64(11):3522-3530.
    • (2012) Arthritis and Rheumatism , vol.64 , Issue.11 , pp. 3522-3530
    • Mikuls, T.R.1    Thiele, G.M.2    Deane, K.D.3    Payne, J.B.4    O'Dell, J.R.5    Yu, F.6
  • 85
    • 34147197618 scopus 로고    scopus 로고
    • High anti-collagen type-II antibody levels and induction of proinflammatory cytokines by anti-collagen antibody-containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the time of disease onset
    • Mullazehi M., Mathsson L., Lampa J., Rönnelid J. High anti-collagen type-II antibody levels and induction of proinflammatory cytokines by anti-collagen antibody-containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the time of disease onset. Annals of the Rheumatic Diseases 2006, 66(4):537-541.
    • (2006) Annals of the Rheumatic Diseases , vol.66 , Issue.4 , pp. 537-541
    • Mullazehi, M.1    Mathsson, L.2    Lampa, J.3    Rönnelid, J.4
  • 86
    • 77953627756 scopus 로고    scopus 로고
    • Carbamylation-dependent activation of T cells: A novel mechanism in the pathogenesis of autoimmune arthritis
    • Mydel P., Wang Z., Brisslert M., Hellvard A., Dahlberg L.E., Hazen S.L., et al. Carbamylation-dependent activation of T cells: A novel mechanism in the pathogenesis of autoimmune arthritis. Journal of Immunology 2010, 184(12):6882-6890.
    • (2010) Journal of Immunology , vol.184 , Issue.12 , pp. 6882-6890
    • Mydel, P.1    Wang, Z.2    Brisslert, M.3    Hellvard, A.4    Dahlberg, L.E.5    Hazen, S.L.6
  • 87
    • 38149006291 scopus 로고    scopus 로고
    • Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation
    • Nandakumar K.S., Bajtner E., Hill L., Böhm B., Rowley M.J., Burkhardt H., et al. Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation. Arthritis and Rheumatism 2008, 58(1):184-196.
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.1 , pp. 184-196
    • Nandakumar, K.S.1    Bajtner, E.2    Hill, L.3    Böhm, B.4    Rowley, M.J.5    Burkhardt, H.6
  • 89
    • 43649104094 scopus 로고    scopus 로고
    • The recombinant humanized anti-IL-6 receptor antibody tocilizumab, an innovative drug for the treatment of rheumatoid arthritis
    • Ohsugi Y., Kishimoto T. The recombinant humanized anti-IL-6 receptor antibody tocilizumab, an innovative drug for the treatment of rheumatoid arthritis. Expert Opinion on Biological Therapy 2008, 8(5):669-681.
    • (2008) Expert Opinion on Biological Therapy , vol.8 , Issue.5 , pp. 669-681
    • Ohsugi, Y.1    Kishimoto, T.2
  • 91
    • 5644239636 scopus 로고    scopus 로고
    • A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis
    • Padyukov L., Silva C., Stolt P., Alfredsson L., Klareskog L. A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. Arthritis and Rheumatism 2004, 50(10):3085-3092.
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.10 , pp. 3085-3092
    • Padyukov, L.1    Silva, C.2    Stolt, P.3    Alfredsson, L.4    Klareskog, L.5
  • 92
    • 31144432093 scopus 로고    scopus 로고
    • BiP regulates autoimmune inflammation and tissue damage
    • Panayi G.S., Corrigall V.M. BiP regulates autoimmune inflammation and tissue damage. Autoimmunity Reviews 2006, 5(2):140-142.
    • (2006) Autoimmunity Reviews , vol.5 , Issue.2 , pp. 140-142
    • Panayi, G.S.1    Corrigall, V.M.2
  • 93
    • 34248587913 scopus 로고    scopus 로고
    • Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: A nationwide case-control study in Denmark
    • Pedersen M., Jacobsen S., Garred P., Madsen H.O., Klarlund M., Svejgaard A., et al. Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: A nationwide case-control study in Denmark. Arthritis and Rheumatism 2007, 56(5):1446-1453.
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.5 , pp. 1446-1453
    • Pedersen, M.1    Jacobsen, S.2    Garred, P.3    Madsen, H.O.4    Klarlund, M.5    Svejgaard, A.6
  • 94
    • 28144441356 scopus 로고    scopus 로고
    • Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: Association of susceptibility with PTPN22, CTLA4, and PADI4
    • Plenge R.M., Padyukov L., Remmers E.F., Purcell S., Lee A.T., Karlson E.W., et al. Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: Association of susceptibility with PTPN22, CTLA4, and PADI4. American Journal of Human Genetics 2005, 77(6):1044-1060.
    • (2005) American Journal of Human Genetics , vol.77 , Issue.6 , pp. 1044-1060
    • Plenge, R.M.1    Padyukov, L.2    Remmers, E.F.3    Purcell, S.4    Lee, A.T.5    Karlson, E.W.6
  • 98
    • 18744430797 scopus 로고    scopus 로고
    • Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis
    • Rantapää-Dahlqvist S., de Jong B.A., Berglin E., Hallmans G., Wadell G., Stenlund H., et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis and Rheumatism 2003, 48(10):2741-2749.
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.10 , pp. 2741-2749
    • Rantapää-Dahlqvist, S.1    de Jong, B.A.2    Berglin, E.3    Hallmans, G.4    Wadell, G.5    Stenlund, H.6
  • 99
    • 75749099775 scopus 로고    scopus 로고
    • Recent advances in the genetics of rheumatoid arthritis
    • Raychaudhuri S. Recent advances in the genetics of rheumatoid arthritis. Current Opinion in Rheumatology 2010, 22(2):109-118.
    • (2010) Current Opinion in Rheumatology , vol.22 , Issue.2 , pp. 109-118
    • Raychaudhuri, S.1
  • 100
    • 84862776511 scopus 로고    scopus 로고
    • Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
    • Raychaudhuri S., Sandor C., Stahl E.A., Freudenberg J., Lee H.S., Jia X., et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nature Genetics 2012, 44(3):291-296.
    • (2012) Nature Genetics , vol.44 , Issue.3 , pp. 291-296
    • Raychaudhuri, S.1    Sandor, C.2    Stahl, E.A.3    Freudenberg, J.4    Lee, H.S.5    Jia, X.6
  • 107
    • 84867054370 scopus 로고    scopus 로고
    • Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis
    • Scher J.U., Ubeda C., Equinda M., Khanin R., Buischi Y., Viale A., et al. Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis. Arthritis and Rheumatism 2012, 64(10):3083-3094.
    • (2012) Arthritis and Rheumatism , vol.64 , Issue.10 , pp. 3083-3094
    • Scher, J.U.1    Ubeda, C.2    Equinda, M.3    Khanin, R.4    Buischi, Y.5    Viale, A.6
  • 109
    • 81455161068 scopus 로고    scopus 로고
    • Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis
    • Shoda H., Fujio K., Shibuya M., Okamura T., Sumitomo S., Okamoto A., et al. Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis. Arthritis Research & Therapy 2011, 13(6):R191.
    • (2011) Arthritis Research & Therapy , vol.13 , Issue.6
    • Shoda, H.1    Fujio, K.2    Shibuya, M.3    Okamura, T.4    Sumitomo, S.5    Okamoto, A.6
  • 110
    • 0030839970 scopus 로고    scopus 로고
    • Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease
    • Skriner K., Sommergruber W.H., Tremmel V., Fischer I., Barta A., Smolen J.S., et al. Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease. The Journal of Clinical Investigation 1997, 100(1):127-135.
    • (1997) The Journal of Clinical Investigation , vol.100 , Issue.1 , pp. 127-135
    • Skriner, K.1    Sommergruber, W.H.2    Tremmel, V.3    Fischer, I.4    Barta, A.5    Smolen, J.S.6
  • 112
    • 74849107568 scopus 로고    scopus 로고
    • Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients
    • Snir O., Widhe M., Hermansson M., von Spee C., Lindberg J., Hensen S., et al. Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis and Rheumatism 2010, 62(1):44-52.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.1 , pp. 44-52
    • Snir, O.1    Widhe, M.2    Hermansson, M.3    von Spee, C.4    Lindberg, J.5    Hensen, S.6
  • 113
    • 66149124137 scopus 로고    scopus 로고
    • Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: Association with HLA-DRB1 alleles
    • Snir O., Widhe M., von Spee C., Lindberg J., Padyukov L., Lundberg K., et al. Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: Association with HLA-DRB1 alleles. Annals of the Rheumatic Diseases 2009, 68(5):736-743.
    • (2009) Annals of the Rheumatic Diseases , vol.68 , Issue.5 , pp. 736-743
    • Snir, O.1    Widhe, M.2    von Spee, C.3    Lindberg, J.4    Padyukov, L.5    Lundberg, K.6
  • 114
    • 84860848914 scopus 로고    scopus 로고
    • Development and deployment of antigen arrays for investigation of B-cell fine specificity in autoimmune disease
    • Sokolove J., Lindstrom T.M., Robinson W.H. Development and deployment of antigen arrays for investigation of B-cell fine specificity in autoimmune disease. Frontiers in Bioscience (Elite Edition) 2012, 4:320-330.
    • (2012) Frontiers in Bioscience (Elite Edition) , vol.4 , pp. 320-330
    • Sokolove, J.1    Lindstrom, T.M.2    Robinson, W.H.3
  • 115
    • 78650779270 scopus 로고    scopus 로고
    • Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor
    • Sokolove J., Zhao X., Chandra P.E., Robinson W.H. Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor. Arthritis and Rheumatism 2011, 63(1):53-62.
    • (2011) Arthritis and Rheumatism , vol.63 , Issue.1 , pp. 53-62
    • Sokolove, J.1    Zhao, X.2    Chandra, P.E.3    Robinson, W.H.4
  • 116
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • Stahl E.A., Raychaudhuri S., Remmers E.F., Xie G., Eyre S., Thomson B.P., et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nature Genetics 2010, 42(6):508-514.
    • (2010) Nature Genetics , vol.42 , Issue.6 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3    Xie, G.4    Eyre, S.5    Thomson, B.P.6
  • 117
    • 0017157626 scopus 로고
    • Mixed lymphocyte cultures in rheumatoid arthritis
    • Stastny P. Mixed lymphocyte cultures in rheumatoid arthritis. The Journal of Clinical Investigation 1976, 57(5):1148-1157.
    • (1976) The Journal of Clinical Investigation , vol.57 , Issue.5 , pp. 1148-1157
    • Stastny, P.1
  • 118
    • 84857793524 scopus 로고    scopus 로고
    • Decisions about dendritic cells: Past, present, and future
    • Steinman R.M. Decisions about dendritic cells: Past, present, and future. Annual Review of Immunology 2011, 30:1-22.
    • (2011) Annual Review of Immunology , vol.30 , pp. 1-22
    • Steinman, R.M.1
  • 119
    • 0041885145 scopus 로고    scopus 로고
    • Quantification of the influence of cigarette smoking on rheumatoid arthritis: Results from a population based case-control study, using incident cases
    • Stolt P., Bengtsson C., Nordmark B., Lindblad S., Lundberg I., Klareskog L., et al. Quantification of the influence of cigarette smoking on rheumatoid arthritis: Results from a population based case-control study, using incident cases. Annals of the Rheumatic Diseases 2003, 62(9):835-841.
    • (2003) Annals of the Rheumatic Diseases , vol.62 , Issue.9 , pp. 835-841
    • Stolt, P.1    Bengtsson, C.2    Nordmark, B.3    Lindblad, S.4    Lundberg, I.5    Klareskog, L.6
  • 120
    • 77953694440 scopus 로고    scopus 로고
    • Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis
    • Stolt P., Yahya A., Bengtsson C., Källberg H., Rönnelid J., Lundberg I., et al. Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis. Annals of the Rheumatic Diseases 2010, 69(6):1072-1076.
    • (2010) Annals of the Rheumatic Diseases , vol.69 , Issue.6 , pp. 1072-1076
    • Stolt, P.1    Yahya, A.2    Bengtsson, C.3    Källberg, H.4    Rönnelid, J.5    Lundberg, I.6
  • 121
    • 72349096793 scopus 로고    scopus 로고
    • Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit
    • Sun J.B., Czerkinsky C., Holmgren J. Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scandinavian Journal of Immunology 2010, 71(1):1-11. 10.1111/j.1365-3083.2009.02321.x.
    • (2010) Scandinavian Journal of Immunology , vol.71 , Issue.1 , pp. 1-11
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 123
    • 33748563609 scopus 로고    scopus 로고
    • Aspects of early arthritis. What determines the evolution of early undifferentiated arthritis and rheumatoid arthritis? An update from the Norfolk Arthritis Register
    • Symmons D.P., Silman A.J. Aspects of early arthritis. What determines the evolution of early undifferentiated arthritis and rheumatoid arthritis? An update from the Norfolk Arthritis Register. Arthritis Research & Therapy 2006, 8(4):214.
    • (2006) Arthritis Research & Therapy , vol.8 , Issue.4 , pp. 214
    • Symmons, D.P.1    Silman, A.J.2
  • 124
    • 36549005027 scopus 로고    scopus 로고
    • Rheumatoid arthritis association at 6q23
    • Epub 2007 Nov 4
    • Thomson W., Barton A., Ke X., Eyre S., Hinks A., Bowes J., et al. Rheumatoid arthritis association at 6q23. Nature Genetics 2007, 39(12):1431-1433. Epub 2007 Nov 4.
    • (2007) Nature Genetics , vol.39 , Issue.12 , pp. 1431-1433
    • Thomson, W.1    Barton, A.2    Ke, X.3    Eyre, S.4    Hinks, A.5    Bowes, J.6
  • 125
    • 36849031722 scopus 로고    scopus 로고
    • Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning
    • Epub 2007 Oct 31. Erratum in: Journal of Immunological Methods, 334(1-2), 142, 2008
    • Tiller T., Meffre E., Yurasov S., Tsuiji M., Nussenzweig M.C., Wardemann H. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning. Journal of Immunological Methods 2008, 329(1-2):112-124. Epub 2007 Oct 31. Erratum in: Journal of Immunological Methods, 334(1-2), 142, 2008.
    • (2008) Journal of Immunological Methods , vol.329 , Issue.1-2 , pp. 112-124
    • Tiller, T.1    Meffre, E.2    Yurasov, S.3    Tsuiji, M.4    Nussenzweig, M.C.5    Wardemann, H.6
  • 126
    • 84878027366 scopus 로고    scopus 로고
    • Autoimmunity in rheumatoid arthritis: Different antigens-Common principles
    • [Epub ahead of print]
    • Trouw L.A., Huizinga T.W., Toes R.E. Autoimmunity in rheumatoid arthritis: Different antigens-Common principles. Annals of the Rheumatic Diseases 2012, [Epub ahead of print].
    • (2012) Annals of the Rheumatic Diseases
    • Trouw, L.A.1    Huizinga, T.W.2    Toes, R.E.3
  • 128
    • 84871798688 scopus 로고    scopus 로고
    • The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin
    • van Beers J.J., Schwarte C.M., Stammen-Vogelzangs J., Oosterink E., Božič B., Pruijn G.J. The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and β-actin. Arthritis and Rheumatism 2013, 65(1):69-80.
    • (2013) Arthritis and Rheumatism , vol.65 , Issue.1 , pp. 69-80
    • van Beers, J.J.1    Schwarte, C.M.2    Stammen-Vogelzangs, J.3    Oosterink, E.4    Božič, B.5    Pruijn, G.J.6
  • 130
    • 78650773793 scopus 로고    scopus 로고
    • Classification of rheumatoid arthritis: Comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European League Against Rheumatism criteria
    • van der Linden M.P., Knevel R., Huizinga T.W., van der Helm-van Mil A.H. Classification of rheumatoid arthritis: Comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European League Against Rheumatism criteria. Arthritis and Rheumatism 2011, 63(1):37-42.
    • (2011) Arthritis and Rheumatism , vol.63 , Issue.1 , pp. 37-42
    • van der Linden, M.P.1    Knevel, R.2    Huizinga, T.W.3    van der Helm-van Mil, A.H.4
  • 131
    • 77957588055 scopus 로고    scopus 로고
    • Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis
    • van der Woude D., Alemayehu W.G., Verduijn W., de Vries R.R., Houwing-Duistermaat J.J., Huizinga T.W., et al. Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis. Nature Genetics 2010, 42(10):814-816.
    • (2010) Nature Genetics , vol.42 , Issue.10 , pp. 814-816
    • van der Woude, D.1    Alemayehu, W.G.2    Verduijn, W.3    de Vries, R.R.4    Houwing-Duistermaat, J.J.5    Huizinga, T.W.6
  • 134
    • 34748812426 scopus 로고    scopus 로고
    • On the occurrence of a factor in human serum activating the specific agglutintion of sheep blood corpuscles. 1939
    • discussion 439
    • Waaler E. On the occurrence of a factor in human serum activating the specific agglutintion of sheep blood corpuscles. 1939. APMIS 2007, 15(5):422-438. discussion 439.
    • (2007) APMIS , vol.15 , Issue.5 , pp. 422-438
    • Waaler, E.1
  • 135
    • 84856416212 scopus 로고    scopus 로고
    • Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy
    • 551.e1-7
    • Wambre E., DeLong J.H., James E.A., LaFond R.E., Robinson D., Kwok W.W. Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy. The Journal of Allergy and Clinical Immunology 2011, 129(2):544-551. 551.e1-7.
    • (2011) The Journal of Allergy and Clinical Immunology , vol.129 , Issue.2 , pp. 544-551
    • Wambre, E.1    DeLong, J.H.2    James, E.A.3    LaFond, R.E.4    Robinson, D.5    Kwok, W.W.6
  • 136
  • 137
    • 73249145617 scopus 로고    scopus 로고
    • Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis
    • Wegner N., Lundberg K., Kinloch A., Fisher B., Malmström V., Feldmann M., et al. Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis. Immunological Reviews 2010, 233(1):34-54.
    • (2010) Immunological Reviews , vol.233 , Issue.1 , pp. 34-54
    • Wegner, N.1    Lundberg, K.2    Kinloch, A.3    Fisher, B.4    Malmström, V.5    Feldmann, M.6
  • 138
    • 77955733490 scopus 로고    scopus 로고
    • Peptidylarginine deiminase from Pophyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis
    • Wegner N., Wait R., Sroka A., Eick S., Nguyen K.A., Lundberg K., et al. Peptidylarginine deiminase from Pophyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis. Arthritis and Rheumatism 2010, 62(9):2662-2672.
    • (2010) Arthritis and Rheumatism , vol.62 , Issue.9 , pp. 2662-2672
    • Wegner, N.1    Wait, R.2    Sroka, A.3    Eick, S.4    Nguyen, K.A.5    Lundberg, K.6
  • 140
    • 79959824881 scopus 로고    scopus 로고
    • The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens
    • Willemze A., van der Woude D., Ghidey W., Levarht E.W., Stoeken-Rijsbergen G., Verduyn W., et al. The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens. Arthritis and Rheumatism 2011, 63(7):1823-1832.
    • (2011) Arthritis and Rheumatism , vol.63 , Issue.7 , pp. 1823-1832
    • Willemze, A.1    van der Woude, D.2    Ghidey, W.3    Levarht, E.W.4    Stoeken-Rijsbergen, G.5    Verduyn, W.6
  • 141
    • 0019512029 scopus 로고
    • Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates
    • Wooley P.H., Luthra H.S., Stuart J.M., David C.S. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. The Journal of Experimental Medicine 1981, 154(3):688-700.
    • (1981) The Journal of Experimental Medicine , vol.154 , Issue.3 , pp. 688-700
    • Wooley, P.H.1    Luthra, H.S.2    Stuart, J.M.3    David, C.S.4
  • 142
    • 84860241847 scopus 로고    scopus 로고
    • Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
    • Zielinski C.E., Mele F., Aschenbrenner D., Jarrossay D., Ronchi F., Gattorno M., et al. Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. Nature 2012, 484(7395):514-518.
    • (2012) Nature , vol.484 , Issue.7395 , pp. 514-518
    • Zielinski, C.E.1    Mele, F.2    Aschenbrenner, D.3    Jarrossay, D.4    Ronchi, F.5    Gattorno, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.