메뉴 건너뛰기




Volumn 109, Issue 11, 2013, Pages 1923-1933

Dose-response to 3 months of quercetin-containing supplements on metabolite and quercetin conjugate profile in adults

Author keywords

Dietary supplements; Flavonols; Metabolic profiling; Quercetin conjugates

Indexed keywords

2 HYDROXY 4 METHYLTHIOBUTYRIC ACID; 2 PHOSPHONOOXYACETIC ACID; 2,4 DIAMINOBUTYRIC ACID; ACETIC ACID DERIVATIVE; ALLOCYSTATHIONINE; ASCORBIC ACID; BILE ACID; BILIVERDIN; COLECALCIFEROL DERIVATIVE; CYSTATHIONINE; DIACYLGLYCEROL; ELAIDIC ACID; GLUCURONIDE; GUAIACOL; LINOLEIC ACID; NICOTINIC ACID; PALMITIC ACID; PHOSPHATIDYLCHOLINE; QUERCETIN; QUERCETIN 3 GLUCURONIDE; QUERCETIN 3 SULPHATE; QUERCETIN DERIVATIVE; QUERCETIN DIGLUCURONIDE; STEARIC ACID; TETRAHYDROCORTICOSTERONE; UBIQUINONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84877997806     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512003972     Document Type: Article
Times cited : (43)

References (48)
  • 1
    • 70449593430 scopus 로고    scopus 로고
    • US Department of Agriculture, Agricultural Research Service Nutrient Data Laboratory Home page
    • US Department of Agriculture, Agricultural Research Service (2011) USDA Database for the Flavonoid Content of Selected Foods, release 3.0. Nutrient Data Laboratory Home page. http://www.ars.usda.gov/nutrientdata/flav
    • (2011) USDA Database for the Flavonoid Content of Selected Foods, Release 3.0
  • 2
    • 45849085449 scopus 로고    scopus 로고
    • The influence of wine polyphenols on reactive oxygen and nitrogen species production by murine macrophages RAW 264.7
    • Ciz M, Pavelkova M, Gallova L, et al. (2008) The influence of wine polyphenols on reactive oxygen and nitrogen species production by murine macrophages RAW 264.7. Physiol Res 57, 393-402.
    • (2008) Physiol Res , vol.57 , pp. 393-402
    • Ciz, M.1    Pavelkova, M.2    Gallova, L.3
  • 3
    • 71949125739 scopus 로고    scopus 로고
    • Flavonoids inhibit the genotoxicity of hydrogen peroxide (H(2)O(2)) and of the food mutagen 2-amino-3-methylima-dazo[4, 5-f]-quinoline (IQ) in lymphocytes from patients with inflammatory bowel disease (IBD)
    • Najafzadeh M, Reynolds PD, Baumgartner A, et al. (2009) Flavonoids inhibit the genotoxicity of hydrogen peroxide (H(2)O(2)) and of the food mutagen 2-amino-3-methylima-dazo[4, 5-f]-quinoline (IQ) in lymphocytes from patients with inflammatory bowel disease (IBD). Mutagenesis 24, 405-411.
    • (2009) Mutagenesis , vol.24 , pp. 405-411
    • Najafzadeh, M.1    Reynolds, P.D.2    Baumgartner, A.3
  • 4
    • 26444581298 scopus 로고    scopus 로고
    • Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats
    • Dias AS, Porawski M, Alonso M, et al. (2005) Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats. J Nutr 135, 2299-2304.
    • (2005) J Nutr , vol.135 , pp. 2299-2304
    • Dias, A.S.1    Porawski, M.2    Alonso, M.3
  • 5
    • 14744294057 scopus 로고    scopus 로고
    • In vivo quercitrin anti-inflammatory effect involves release of quer-cetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway
    • Comalada M, Camuesco D, Sierra S, et al. (2005) In vivo quercitrin anti-inflammatory effect involves release of quer-cetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway. Eur J Immunol 35, 584-592.
    • (2005) Eur J Immunol , vol.35 , pp. 584-592
    • Comalada, M.1    Camuesco, D.2    Sierra, S.3
  • 6
    • 33748580218 scopus 로고    scopus 로고
    • Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: Analysis of the structure-activity relationship
    • Comalada M, Ballester I, Bailon E, et al. (2006) Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship. Biochem Pharmacol 72, 1010-1021.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1010-1021
    • Comalada, M.1    Ballester, I.2    Bailon, E.3
  • 7
    • 33645541093 scopus 로고    scopus 로고
    • The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta system
    • Nair MP, Mahajan S, Reynolds JL, et al. (2006) The flavonoid quercetin inhibits proinflammatory cytokine (tumor necrosis factor alpha) gene expression in normal peripheral blood mononuclear cells via modulation of the NF-kappa beta system. Clin Vaccine Immunol 13, 319-328.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 319-328
    • Nair, M.P.1    Mahajan, S.2    Reynolds, J.L.3
  • 8
    • 0041527063 scopus 로고    scopus 로고
    • In vitro antiviral activities of Caesalpinia pulcherrima and its related flavo-noids
    • Chiang LC, Chiang W, Liu MC, et al. (2003) In vitro antiviral activities of Caesalpinia pulcherrima and its related flavo-noids. J Antimicrob Chemother 52, 194-198.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 194-198
    • Chiang, L.C.1    Chiang, W.2    Liu, M.C.3
  • 9
    • 33750496903 scopus 로고    scopus 로고
    • Binding interaction of quer-cetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): Structure-activity relationship studies reveal salient pharmacophore features
    • Chen L, Li J, Luo C, et al. (2006) Binding interaction of quer-cetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features. Bioorg Med Chem 14, 8295-8306.
    • (2006) Bioorg Med Chem , vol.14 , pp. 8295-8306
    • Chen, L.1    Li, J.2    Luo, C.3
  • 10
  • 11
  • 12
    • 0023918014 scopus 로고
    • Antiviral activity of flavones and potentiation by ascorbate
    • Vrijsen R, Everaert L & Boeye A (1988) Antiviral activity of flavones and potentiation by ascorbate. J Gen Virol 69, 1749-1751.
    • (1988) J Gen Virol , vol.69 , pp. 1749-1751
    • Vrijsen, R.1    Everaert, L.2    Boeye, A.3
  • 13
    • 0042884320 scopus 로고    scopus 로고
    • Safety-assessment of 3-methoxyquercetin as an antirhinoviral compound for nasal application: Effect on ciliary beat frequency
    • Dimova S, Mugabowindekwe R, Willems T, et al. (2003) Safety-assessment of 3-methoxyquercetin as an antirhinoviral compound for nasal application: effect on ciliary beat frequency. Int J Pharm 263, 95-103.
    • (2003) Int J Pharm , vol.263 , pp. 95-103
    • Dimova, S.1    Mugabowindekwe, R.2    Willems, T.3
  • 14
    • 77952880084 scopus 로고    scopus 로고
    • Changes of metabolic profiles in urine after oral administration of quercetin in rats
    • An D, Zhang Q, Wu S, et al. (2010) Changes of metabolic profiles in urine after oral administration of quercetin in rats. Food Chem Toxicol 48, 1521-1527.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1521-1527
    • An, D.1    Zhang, Q.2    Wu, S.3
  • 15
    • 63349090883 scopus 로고    scopus 로고
    • Rutin inhibits the proliferation of murine leukemia WEHI-3 cells in vivo and promotes immune response in vivo
    • Lin JP, Yang JS, Lu CC, et al. (2009) Rutin inhibits the proliferation of murine leukemia WEHI-3 cells in vivo and promotes immune response in vivo. Leuk Res 33, 823-828.
    • (2009) Leuk Res , vol.33 , pp. 823-828
    • Lin, J.P.1    Yang, J.S.2    Lu, C.C.3
  • 16
    • 0037121533 scopus 로고    scopus 로고
    • The flavo-noid, quercetin, differentially regulates Th-1 (IFNgamma) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells
    • Nair MP, Kandaswami C, Mahajan S, et al. (2002) The flavo-noid, quercetin, differentially regulates Th-1 (IFNgamma) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells. Biochim Biophys Acta 1593, 29-36.
    • (2002) Biochim Biophys Acta , vol.1593 , pp. 29-36
    • Nair, M.P.1    Kandaswami, C.2    Mahajan, S.3
  • 17
    • 0036721149 scopus 로고    scopus 로고
    • Flavonoid intake and risk of chronic diseases
    • Knekt P, Kumpulainen J, Jarvinen R, et al. (2002) Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 76, 560-568.
    • (2002) Am J Clin Nutr , vol.76 , pp. 560-568
    • Knekt, P.1    Kumpulainen, J.2    Jarvinen, R.3
  • 18
    • 9744242794 scopus 로고    scopus 로고
    • Dietary flavonoids and cancer risk: Evidence from human population studies
    • Neuhouser ML (2004) Dietary flavonoids and cancer risk: evidence from human population studies. Nutr Cancer 50, 1-7.
    • (2004) Nutr Cancer , vol.50 , pp. 1-7
    • Neuhouser, M.L.1
  • 19
    • 33947095990 scopus 로고    scopus 로고
    • Flavonoids and heart health: Proceedings of the ILSI North America Fla-vonoids Workshop, May 31-June 1, 2005, Washington, DC
    • Erdman JW Jr, Balentine D, Arab L, et al. (2007) Flavonoids and heart health: proceedings of the ILSI North America Fla-vonoids Workshop, May 31-June 1, 2005, Washington, DC. J Nutr 137, 718S-737S.
    • (2007) J Nutr , vol.137
    • Erdman, Jr.J.W.1    Balentine, D.2    Arab, L.3
  • 20
    • 33847789892 scopus 로고    scopus 로고
    • Flavonoid intake and cardiovascular disease mortality: A prospective study in postmenopausal women
    • Mink PJ, Scrafford CG, Barraj LM, et al. (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 85, 895-909.
    • (2007) Am J Clin Nutr , vol.85 , pp. 895-909
    • Mink, P.J.1    Scrafford, C.G.2    Barraj, L.M.3
  • 21
    • 65949090502 scopus 로고    scopus 로고
    • Querce-tin increases brain and muscle mitochondrial biogenesis and exercise tolerance
    • Davis JM, Murphy EA, Carmichael MD, et al. (2009) Querce-tin increases brain and muscle mitochondrial biogenesis and exercise tolerance. Am J Physiol Regul Integr Comp Physiol 296, R1071-R1077.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296
    • Davis, J.M.1    Murphy, E.A.2    Carmichael, M.D.3
  • 22
    • 35848966547 scopus 로고    scopus 로고
    • Quercetin reduces blood pressure in hypertensive subjects
    • Edwards RL, Lyon T, Litwin SE, et al. (2007) Quercetin reduces blood pressure in hypertensive subjects. J Nutr 137, 2405-2411.
    • (2007) J Nutr , vol.137 , pp. 2405-2411
    • Edwards, R.L.1    Lyon, T.2    Litwin, S.E.3
  • 23
    • 73749083955 scopus 로고    scopus 로고
    • Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: A double-blinded, placebo-controlled cross-over study
    • Egert S, Bosy-Westphal A, Seiberl J, et al. (2009) Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. Br J Nutr 102, 1065-1074.
    • (2009) Br J Nutr , vol.102 , pp. 1065-1074
    • Egert, S.1    Bosy-Westphal, A.2    Seiberl, J.3
  • 24
    • 79953035889 scopus 로고    scopus 로고
    • Influence of quercetin supplementation on disease risk factors in community-dwelling adults
    • Knab AM, Shanely RA, Henson DA, et al. (2011) Influence of quercetin supplementation on disease risk factors in community-dwelling adults. J Am Diet Assoc 111, 542-549.
    • (2011) J Am Diet Assoc , vol.111 , pp. 542-549
    • Knab, A.M.1    Shanely, R.A.2    Henson, D.A.3
  • 25
    • 51049095905 scopus 로고    scopus 로고
    • Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans
    • Egert S, Wolffram S, Bosy-Westphal A, et al. (2008) Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr 138, 1615-1621.
    • (2008) J Nutr , vol.138 , pp. 1615-1621
    • Egert, S.1    Wolffram, S.2    Bosy-Westphal, A.3
  • 26
    • 74549156348 scopus 로고    scopus 로고
    • Quercetin supplementation does not alter antioxidant status in humans
    • Shanely RA, Knab AM, Nieman DC, et al. (2010) Quercetin supplementation does not alter antioxidant status in humans. Free Radic Res 44, 224-231.
    • (2010) Free Radic Res , vol.44 , pp. 224-231
    • Shanely, R.A.1    Knab, A.M.2    Nieman, D.C.3
  • 27
    • 53849146739 scopus 로고    scopus 로고
    • Pure dietary flavonoids quercetin and (2)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
    • Loke WM, Hodgson JM, Proudfoot JM, et al. (2008) Pure dietary flavonoids quercetin and (2)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. Am J Clin Nutr 88, 1018-1025.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1018-1025
    • Loke, W.M.1    Hodgson, J.M.2    Proudfoot, J.M.3
  • 28
    • 74949133831 scopus 로고    scopus 로고
    • Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein e genotype
    • Egert S, Boesch-Saadatmandi C, Wolffram S, et al. (2010) Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype. J Nutr 140, 278-284.
    • (2010) J Nutr , vol.140 , pp. 278-284
    • Egert, S.1    Boesch-Saadatmandi, C.2    Wolffram, S.3
  • 29
    • 79960691818 scopus 로고    scopus 로고
    • Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis
    • Boots AW, Drent M, de Boer VC, et al. (2011) Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis. Clin Nutr 30, 506-512.
    • (2011) Clin Nutr , vol.30 , pp. 506-512
    • Boots, A.W.1    Drent, M.2    De Boer, V.C.3
  • 30
    • 79959353030 scopus 로고    scopus 로고
    • Harnessing metabolomics for nutrition research
    • Zulyniak MA & Mutch DM (2011) Harnessing metabolomics for nutrition research. Curr Pharm Biotechnol 12, 1005-1015.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 1005-1015
    • Zulyniak, M.A.1    Mutch, D.M.2
  • 31
    • 77950493668 scopus 로고    scopus 로고
    • An antiinflam-matory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: A nutrigenomics approach
    • Bakker GC, van Erk MJ, Pellis L, et al. (2010) An antiinflam-matory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach. Am J Clin Nutr 91, 1044-1059.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1044-1059
    • Bakker, G.C.1    Van Erk, M.J.2    Pellis, L.3
  • 32
    • 22144495044 scopus 로고    scopus 로고
    • Tissue distribution of quercetin in rats and pigs
    • de Boer VC, Dihal AA, van der Woude H, et al. (2005) Tissue distribution of quercetin in rats and pigs. J Nutr 135, 1718-1725.
    • (2005) J Nutr , vol.135 , pp. 1718-1725
    • De Boer, V.C.1    Dihal, A.A.2    Van Der Woude, H.3
  • 33
    • 45549093293 scopus 로고    scopus 로고
    • Querce-tin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation
    • Loke WM, Proudfoot JM, McKinley AJ, et al. (2008) Querce-tin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation. J Agric Food Chem 56, 3609-3615.
    • (2008) J Agric Food Chem , vol.56 , pp. 3609-3615
    • Loke, W.M.1    Proudfoot, J.M.2    McKinley, A.J.3
  • 34
    • 42149109611 scopus 로고    scopus 로고
    • Influence of the metabolic profile on the in vivo antioxidant activity of quercetin under a low dosage oral regimen in rats
    • Santos MR, Rodriguez-Gomez MJ, Justino GC, et al. (2008) Influence of the metabolic profile on the in vivo antioxidant activity of quercetin under a low dosage oral regimen in rats. Br J Pharmacol 153, 1750-1761.
    • (2008) Br J Pharmacol , vol.153 , pp. 1750-1761
    • Santos, M.R.1    Rodriguez-Gomez, M.J.2    Justino, G.C.3
  • 35
    • 33746698897 scopus 로고    scopus 로고
    • Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl-and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions
    • Mullen W, Edwards CA & Crozier A (2006) Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl-and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions. Br J Nutr 96, 107-116.
    • (2006) Br J Nutr , vol.96 , pp. 107-116
    • Mullen, W.1    Edwards, C.A.2    Crozier, A.3
  • 36
    • 84863399512 scopus 로고    scopus 로고
    • Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules
    • Egert S, Wolffram S, Schulze B, et al. (2012) Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules. Br J Nutr 107, 539-546.
    • (2012) Br J Nutr , vol.107 , pp. 539-546
    • Egert, S.1    Wolffram, S.2    Schulze, B.3
  • 37
    • 0034515214 scopus 로고    scopus 로고
    • The Anti Cancer Council of Victoria FFQ: Relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation
    • Hodge A, Patterson AJ, Brown WJ, et al. (2000) The Anti Cancer Council of Victoria FFQ: relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation. Aust N Z J Public Health 24, 576-583.
    • (2000) Aust N Z J Public Health , vol.24 , pp. 576-583
    • Hodge, A.1    Patterson, A.J.2    Brown, W.J.3
  • 38
    • 77957252267 scopus 로고    scopus 로고
    • A 12-week supplementation with quercetin does not affect natural killer cell activity, granulocyte oxidative burst activity or granulo-cyte phagocytosis in female human subjects
    • Heinz SA, Henson DA, Nieman DC, et al. (2010) A 12-week supplementation with quercetin does not affect natural killer cell activity, granulocyte oxidative burst activity or granulo-cyte phagocytosis in female human subjects. Br J Nutr 104, 849-857.
    • (2010) Br J Nutr , vol.104 , pp. 849-857
    • Heinz, S.A.1    Henson, D.A.2    Nieman, D.C.3
  • 39
    • 84856350756 scopus 로고    scopus 로고
    • Combined fruit and vegetable intake is correlated with improved inflammatory and oxidant status from a cross-sectional study in a community setting
    • Root MM, McGinn MC, Nieman DC, et al. (2012) Combined fruit and vegetable intake is correlated with improved inflammatory and oxidant status from a cross-sectional study in a community setting. Nutrients 4, 29-41.
    • (2012) Nutrients , vol.4 , pp. 29-41
    • Root, M.M.1    McGinn, M.C.2    Nieman, D.C.3
  • 40
    • 70350028279 scopus 로고    scopus 로고
    • Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS
    • Qiu Y, Cai G, Su M, et al. (2009) Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS. J Proteome Res 8, 4844-4850.
    • (2009) J Proteome Res , vol.8 , pp. 4844-4850
    • Qiu, Y.1    Cai, G.2    Su, M.3
  • 41
    • 77949822339 scopus 로고    scopus 로고
    • Urinary metabonomic study on colorectal cancer
    • Qiu Y, Cai G, Su M, et al. (2010) Urinary metabonomic study on colorectal cancer. J Proteome Res 9, 1627-1634.
    • (2010) J Proteome Res , vol.9 , pp. 1627-1634
    • Qiu, Y.1    Cai, G.2    Su, M.3
  • 42
    • 58149202163 scopus 로고    scopus 로고
    • HMDB: A knowledgebase for the human metabolome
    • Wishart DS, Knox C, Guo AC, et al. (2009) HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res 37, D603-D610.
    • (2009) Nucleic Acids Res , vol.37
    • Wishart, D.S.1    Knox, C.2    Guo, A.C.3
  • 43
    • 27244440163 scopus 로고    scopus 로고
    • Hydroxyl radical scavenging effects of guaiacol used in traditional dental pulp sedation: Reaction kinetic study
    • Mimurai T, Yazaki K, Sawaki K, et al. (2005) Hydroxyl radical scavenging effects of guaiacol used in traditional dental pulp sedation: reaction kinetic study. Biomed Res 26, 139-145.
    • (2005) Biomed Res , vol.26 , pp. 139-145
    • Mimurai, T.1    Yazaki, K.2    Sawaki, K.3
  • 44
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • Kanehisa M, Goto S, Furumichi M, et al. (2010) KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res 38, D355-D360.
    • (2010) Nucleic Acids Res , vol.38
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3
  • 45
    • 79953715220 scopus 로고    scopus 로고
    • Dealing with methionine/homocysteine sulfur: Cysteine metabolism to taurine and inorganic sulfur
    • Stipanuk MH & Ueki I (2011) Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur. J Inherit Metab Dis 34, 17-32.
    • (2011) J Inherit Metab Dis , vol.34 , pp. 17-32
    • Stipanuk, M.H.1    Ueki, I.2
  • 46
    • 70450220242 scopus 로고    scopus 로고
    • Methionine-derived metabolites in apoptosis: Therapeutic opportunities for inhibitors of their metabolism in chemoresistant cancer cells
    • Quash G & Fournet G (2009) Methionine-derived metabolites in apoptosis: therapeutic opportunities for inhibitors of their metabolism in chemoresistant cancer cells. Curr Med Chem 16, 3686-3700.
    • (2009) Curr Med Chem , vol.16 , pp. 3686-3700
    • Quash, G.1    Fournet, G.2
  • 47
    • 67349151315 scopus 로고    scopus 로고
    • Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta
    • Lodi F, Jimenez R, Moreno L, et al. (2009) Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta. Atherosclerosis 204, 34-39.
    • (2009) Atherosclerosis , vol.204 , pp. 34-39
    • Lodi, F.1    Jimenez, R.2    Moreno, L.3
  • 48
    • 49449084484 scopus 로고    scopus 로고
    • Tissue distribution of quercetin in pigs after long-term dietary supplementation
    • Bieger J, Cermak R, Blank R, et al. (2008) Tissue distribution of quercetin in pigs after long-term dietary supplementation. J Nutr 138, 1417-1420.
    • (2008) J Nutr , vol.138 , pp. 1417-1420
    • Bieger, J.1    Cermak, R.2    Blank, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.