-
1
-
-
84878546143
-
Cytotoxic agents
-
Chapter 61. In: Brunton LL, Chabner BA, Knollmann BC, editors. 12th edition. New York: McGraw-Hill;2011. Available from. Accessed April 16
-
Chabner BA, Bertino J, Cleary J, Ortiz T, Lane A, Supko JG, et al. Chapter 61. Cytotoxic agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's The pharmacological basis of therapeutics. 12th edition. New York: McGraw-Hill;2011. Available from: http://www.accessmedicine. com/content.aspx?aID=16680251. Accessed April 16, 2012.
-
(2012)
Goodman & Gilman's The Pharmacological Basis of Therapeutics
-
-
Chabner, B.A.1
Bertino, J.2
Cleary, J.3
Ortiz, T.4
Lane, A.5
Supko, J.G.6
-
2
-
-
77954347979
-
Small-cell lung cancer: Esmo clinical practice guidelines for diagnosis, treatment and follow-up
-
Sørensen M, Pijls-Johannesma M, Felip E. Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010;21(Suppl 5): v120-5.
-
(2010)
Ann Oncol
, vol.21
, Issue.SUPPL. 5
-
-
Sørensen, M.1
Pijls-Johannesma, M.2
Felip, E.3
-
3
-
-
84862785781
-
Survival of patients with small cell lung carcinoma in taiwan
-
Kuo YH, Lin ZZ, Yang YY, Shao YY, Shau WY, Kuo RN, et al. Survival of patients with small cell lung carcinoma in Taiwan. Oncology 2012;82: 19-24.
-
(2012)
Oncology
, vol.82
, pp. 19-24
-
-
Kuo, Y.H.1
Lin, Z.Z.2
Yang, Y.Y.3
Shao, Y.Y.4
Shau, W.Y.5
Kuo, R.N.6
-
4
-
-
3142668981
-
Chemotherapy for small-cell lung cancer with paraneoplastic nephritic syndrome
-
Kagohashi K, Ohara G, Satoh H, Sekizawa K. Chemotherapy for small-cell lung cancer with paraneoplastic nephritic syndrome. Radiol Oncol 2004;38: 153-4.
-
(2004)
Radiol Oncol
, vol.38
, pp. 153-154
-
-
Kagohashi, K.1
Ohara, G.2
Satoh, H.3
Sekizawa, K.4
-
5
-
-
55449106584
-
Imaging detetection in early lung cancer
-
[Slovenian]
-
Dolenšek M, Bavčar Vodovnik T. [Imaging detetection in early lung cancer]. [Slovenian]. Radiol Oncol 2006;40(Suppl 1): S53-8.
-
(2006)
Radiol Oncol
, vol.40
, Issue.SUPPL. 1
-
-
Dolenšek, M.1
Bavčar Vodovnik, T.2
-
6
-
-
27644434949
-
Molecular biology of the lung cancer
-
Panov SZ. Molecular biology of the lung cancer. Radiol Oncol 2005;39: 197-210.
-
(2005)
Radiol Oncol
, vol.39
, pp. 197-210
-
-
Panov, S.Z.1
-
7
-
-
55449124527
-
Early detetection of lung cancer
-
[Slovenian]
-
Terčelj M. [Early detetection of lung cancer]. [Slovenian]. Radiol Oncol 2006;40(Suppl 1): S59-66.
-
(2006)
Radiol Oncol
, vol.40
, Issue.SUPPL. 1
-
-
Terčelj, M.1
-
8
-
-
0026716516
-
Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-Analysis
-
Warde P, Payne D. Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-Analysis. J Clin Oncol 1992;10: 890-5.
-
(1992)
J Clin Oncol
, vol.10
, pp. 890-895
-
-
Warde, P.1
Payne, D.2
-
9
-
-
0037050354
-
Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer
-
Noda K, Nishiwaki Y, Kawahara M, Negoro S, Sugiura T, Yokoyama A, et al. Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N Engl J Med 2002;346: 85-91.
-
(2002)
N Engl J Med
, vol.346
, pp. 85-91
-
-
Noda, K.1
Nishiwaki, Y.2
Kawahara, M.3
Negoro, S.4
Sugiura, T.5
Yokoyama, A.6
-
10
-
-
33646447066
-
Randomized phase iii trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer
-
Hanna N, Bunn PA Jr, Langer C, Einhorn L, Guthrie T Jr, Beck T, et al. Randomized phase III trial comparing irinotecan/cisplatin with etoposide/cisplatin in patients with previously untreated extensive-stage disease small-cell lung cancer. J Clin Oncol 2006;24: 2038-43.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2038-2043
-
-
Hanna, N.1
Bunn Jr., P.A.2
Langer, C.3
Einhorn, L.4
Guthrie Jr., T.5
Beck, T.6
-
11
-
-
84857338470
-
Management of small cell lung cancer. Recent developments for optimal care
-
Califano R, Abidin AZ, Peck R, Faivre-Finn C, Lorigan P. Management of small cell lung cancer. Recent Developments for Optimal Care. Drugs 2012;72: 471-90.
-
(2012)
Drugs
, vol.72
, pp. 471-490
-
-
Califano, R.1
Abidin, A.Z.2
Peck, R.3
Faivre-Finn, C.4
Lorigan, P.5
-
13
-
-
34248356003
-
Cellular response to etoposide treatment
-
Montecucco A, Biamonti G. Cellular response to etoposide treatment. Cancer Lett 2007;252: 9-18.
-
(2007)
Cancer Lett
, vol.252
, pp. 9-18
-
-
Montecucco, A.1
Biamonti, G.2
-
14
-
-
0005346408
-
The importance of drug scheduling in cancer chemotherapy: Etoposide as an example
-
Hande KR. The importance of drug scheduling in cancer chemotherapy: etoposide as an example. Oncologist 1996;1: 234-9.
-
(1996)
Oncologist
, vol.1
, pp. 234-239
-
-
Hande, K.R.1
-
15
-
-
0021978723
-
High-dose etoposide (vp-16) in small-cell lung cancer
-
Greco FA, Johnson DH, Hande KR, Porter LL, Hainsworth JD, Wolff SN. High-dose etoposide (VP-16) in small-cell lung cancer. Semin Oncol 1985;12(Suppl 2): 42-4.
-
(1985)
Semin Oncol
, vol.12
, Issue.SUPPL. 2
, pp. 42-44
-
-
Greco, F.A.1
Johnson, D.H.2
Hande, K.R.3
Porter, L.L.4
Hainsworth, J.D.5
Wolff, S.N.6
-
16
-
-
0024417601
-
A randomized trial to evaluate the effect of schedule on the activity of etoposide in small-cell lung cancer
-
Slevin ML, Clark PI, Joel SP, Malik S, Osborne RJ, Gregory WM, et al. A randomized trial to evaluate the effect of schedule on the activity of etoposide in small-cell lung cancer. J Clin Oncol 1989;7: 1333-40.
-
(1989)
J Clin Oncol
, vol.7
, pp. 1333-1340
-
-
Slevin, M.L.1
Clark, P.I.2
Joel, S.P.3
Malik, S.4
Osborne, R.J.5
Gregory, W.M.6
-
17
-
-
0029099869
-
Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive stage small-cell lung cancer: A randomized phase iii study of the cancer and leukemia group b
-
Miller AA, Herndon JE II, Hollis DR, Ellerton J, Langleben A, Richards F II, et al. Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive stage small-cell lung cancer: A randomized phase III study of the cancer and leukemia group B. Clin Oncol 1995;13: 1871-9.
-
(1995)
Clin Oncol
, vol.13
, pp. 1871-1879
-
-
Miller, A.A.1
Herndon II, J.E.2
Hollis, D.R.3
Ellerton, J.4
Langleben, A.5
Richards II, F.6
-
18
-
-
20944449940
-
Toxicity of the topoisomerase ii inhibitors
-
Seiter K. Toxicity of the topoisomerase II inhibitors. Expert Opin Drug Saf 2005;4: 219-34.
-
(2005)
Expert Opin Drug Saf
, vol.4
, pp. 219-234
-
-
Seiter, K.1
-
19
-
-
0033510485
-
Current role of oral etoposide in the management of small cell lung cancer
-
Clark PI. Current role of oral etoposide in the management of small cell lung cancer. Drugs 1999: 58(Suppl 3): 17-20.
-
(1999)
Drugs
, vol.58
, Issue.SUPPL. 3
, pp. 17-20
-
-
Clark, P.I.1
-
20
-
-
0028122507
-
Prolonged administration of low-daily dose etoposide: A superior dosing schedule?
-
Greco FA, Hainsworth JD. Prolonged administration of low-daily dose etoposide: a superior dosing schedule? Cancer Chemother Pharmacol 1994;34: 101-4.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 101-104
-
-
Greco, F.A.1
Hainsworth, J.D.2
-
21
-
-
66549109768
-
Small-cell lung cancer: Esmo clinical recommendations for diagnosis, treatment and follow-up
-
Sørensen M, Felip E. Small-cell lung cancer: ESMO Clinical Recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009;20(Suppl 4): iv71-2.
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 4
-
-
Sørensen, M.1
Felip, E.2
-
22
-
-
0031017851
-
Patient preferences for oral versus intravenous palliative chemotherapy
-
Liu G, Franssen E, Fitch MI, Warner E. Patient preferences for oral versus intravenous palliative chemotherapy. J Clin Oncol 1997;15: 110-5.
-
(1997)
J Clin Oncol
, vol.15
, pp. 110-115
-
-
Liu, G.1
Franssen, E.2
Fitch, M.I.3
Warner, E.4
-
23
-
-
0026489650
-
A study of quality of life in cancer patients receiving palliative chemotherapy
-
Payne SA. A study of quality of life in cancer patients receiving palliative chemotherapy. Soc Sci Med 1992;35: 1505-9.
-
(1992)
Soc Sci Med
, vol.35
, pp. 1505-1509
-
-
Payne, S.A.1
-
24
-
-
0026018602
-
A randomized trial to compare intravenous and oral etoposide in combination with cisplatin for the treatment of small cell lung cancer
-
Johnson DH, Ruckdeschel JC, Keller JH, Lyman GH, Kallas GJ, Macdonald J, et al. A randomized trial to compare intravenous and oral etoposide in combination with cisplatin for the treatment of small cell lung cancer. Cancer 1991;67: 245-9.
-
(1991)
Cancer
, vol.67
, pp. 245-249
-
-
Johnson, D.H.1
Ruckdeschel, J.C.2
Keller, J.H.3
Lyman, G.H.4
Kallas, G.J.5
Macdonald, J.6
-
25
-
-
0026849216
-
Potential cost savings of oral versus intravenous etoposide in the treatment of small cell lung cancer
-
Pashko S, Johnson DH. Potential cost savings of oral versus intravenous etoposide in the treatment of small cell lung cancer. Pharmacoeconomics 1992;1: 293-7.
-
(1992)
Pharmacoeconomics
, vol.1
, pp. 293-297
-
-
Pashko, S.1
Johnson, D.H.2
-
26
-
-
0030052559
-
Bioavailability of 50-And 75-mg oral etoposide in lung cancer patients
-
Fujiwara Y, Ohune T, Okusaki K, Niitani K, Sumiyoski H, Takemoto V, et al. Bioavailability of 50-And 75-mg oral etoposide in lung cancer patients. Cancer Chemother Pharmacol 1996;37: 327-31.
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, pp. 327-331
-
-
Fujiwara, Y.1
Ohune, T.2
Okusaki, K.3
Niitani, K.4
Sumiyoski, H.5
Takemoto, V.6
-
27
-
-
0028838201
-
Pharmacological attempts to improve the bioavailability of oral etoposide
-
Joel SP, Clark PI, Heap L, Webster L, Robbins S, Craft H, et al. Pharmacological attempts to improve the bioavailability of oral etoposide. Cancer Chemother Pharmacol 1995;37: 125-33.
-
(1995)
Cancer Chemother Pharmacol
, vol.37
, pp. 125-133
-
-
Joel, S.P.1
Clark, P.I.2
Heap, L.3
Webster, L.4
Robbins, S.5
Craft, H.6
-
28
-
-
0006871659
-
The pharmacokinetics of oral etoposide (vp16-213
-
Harvey VJ, Slevin ML, Joel SP, Barnett MJ, Smythe MM, Ang LM, et al. The pharmacokinetics of oral etoposide (VP16-213). Proc Am Soc Clin Oncol 1984;3: 24.
-
(1984)
Proc Am Soc Clin Oncol
, vol.3
, pp. 24
-
-
Harvey, V.J.1
Slevin, M.L.2
Joel, S.P.3
Barnett, M.J.4
Smythe, M.M.5
Ang, L.M.6
-
29
-
-
0027537102
-
Bioavailability of low-dose oral etoposide
-
Hande KR, Krozely MG, Greco FA, Hainsworth JD, Johnson DH. Bioavailability of low-dose oral etoposide. J Clin Oncol 1993;11: 374-7.
-
(1993)
J Clin Oncol
, vol.11
, pp. 374-377
-
-
Hande, K.R.1
Krozely, M.G.2
Greco, F.A.3
Hainsworth, J.D.4
Johnson, D.H.5
-
30
-
-
0032697303
-
Inter-And intrapatient variability in etoposide kinetics with oral and intravenous drug administration
-
Hande K, Messenger M, Wagner J, Krozely M, Kaul S. Inter-And intrapatient variability in etoposide kinetics with oral and intravenous drug administration. Clin Cancer Res 1999;5: 2742-7.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2742-2747
-
-
Hande, K.1
Messenger, M.2
Wagner, J.3
Krozely, M.4
Kaul, S.5
-
31
-
-
0033430115
-
Population pharmacokinetic approach to compare oral and i.v. Administration of etoposide
-
Würthwein G, Krümpelmann S, Tillmann B, Real E, Schulze-Westhoff P, Jürgens H, et al. Population pharmacokinetic approach to compare oral and i.v. administration of etoposide. Anti-Cancer Drugs 1999;10: 807-14.
-
(1999)
Anti-Cancer Drugs
, vol.10
, pp. 807-814
-
-
Würthwein, G.1
Krümpelmann, S.2
Tillmann, B.3
Real, E.4
Schulze-Westhoff, P.5
Jürgens, H.6
-
32
-
-
0024412440
-
The effect of dose on the bioavailability of oral etoposide: Confirmation of a clinically relevant observation
-
Slevin ML, Joel SP, Whomsley R, Devenport K, Harvey VJ, Osborne RJ, et al. The effect of dose on the bioavailability of oral etoposide: confirmation of a clinically relevant observation. Cancer Chemother Pharmacol 1989;24: 329-31.
-
(1989)
Cancer Chemother Pharmacol
, vol.24
, pp. 329-331
-
-
Slevin, M.L.1
Joel, S.P.2
Whomsley, R.3
Devenport, K.4
Harvey, V.J.5
Osborne, R.J.6
-
33
-
-
0027230829
-
Correlations between clinical pharmacodynamics and pharmacokinetics of cisplatin and etoposide
-
Desoize B, Maréchal F, Cattan A. Correlations between clinical pharmacodynamics and pharmacokinetics of cisplatin and etoposide. Ann Biol Clin 1993;51: 125-8.
-
(1993)
Ann Biol Clin
, vol.51
, pp. 125-128
-
-
Desoize, B.1
Maréchal, F.2
Cattan, A.3
-
34
-
-
55249103429
-
Etoposide pharmacokinetics and survival in patients with small cell lung cancer: A multicentre study
-
You B, Tranchand B, Girard P, Falandry C, Ribba B, Chabaud S, et al. Etoposide pharmacokinetics and survival in patients with small cell lung cancer: A multicentre study. Lung Cancer 2008;62: 261-72.
-
(2008)
Lung Cancer
, vol.62
, pp. 261-272
-
-
You, B.1
Tranchand, B.2
Girard, P.3
Falandry, C.4
Ribba, B.5
Chabaud, S.6
-
35
-
-
80054716758
-
Principles of clinical pharmacology
-
Chapter 5. In: Longo DL Fauci AS Kasper DL Hauser SL Jameson JL Loscalzo J Editors. 18th Edition. New York: McGraw-Hill;2012. Available Form. Accessed April 16
-
Roden DM. Chapter 5. Principles of Clinical Pharmacology. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, editors. Harrison's principles of internal medicine. 18th edition. New York: McGraw-Hill;2012. Available form: http://www.accessmedicine.com/content. aspx?aID=9092427. Accessed April 16, 2012.
-
(2012)
Harrison's Principles Of Internal Medicine
-
-
Roden, D.M.1
-
37
-
-
0035882515
-
Pharmacogenetics of the human drug-Transporter gene mdr1: Impact of polymorphisms on pharmacotherapy
-
Brinkmann U, Roots I, Eichelbaum M. Pharmacogenetics of the human drug-Transporter gene MDR1: impact of polymorphisms on pharmacotherapy. Drug Discov Today 2001;6: 835-9.
-
(2001)
Drug Discov Today
, vol.6
, pp. 835-839
-
-
Brinkmann, U.1
Roots, I.2
Eichelbaum, M.3
-
38
-
-
0344665555
-
Abc of oral bioavailability: Transporters as gatekeepers in the gut
-
Dietrich CG, Geier A, Oude Elferink RPJ. ABC of oral bioavailability: transporters as gatekeepers in the gut. Gut 2003;52: 1788-95.
-
(2003)
Gut
, vol.52
, pp. 1788-1795
-
-
Dietrich, C.G.1
Geier, A.2
Oude Elferink, R.P.J.3
-
39
-
-
0033646441
-
Active efflux kinetics of etoposide from rabbit small intestine and colon
-
Kunta J, Yan J, Makhey VD, Sinko PJ. Active efflux kinetics of etoposide from rabbit small intestine and colon. Biopharm Drug Dispos 2000;21: 83-93.
-
(2000)
Biopharm Drug Dispos
, vol.21
, pp. 83-93
-
-
Kunta, J.1
Yan, J.2
Makhey, V.D.3
Sinko, P.J.4
-
40
-
-
0037444271
-
Mouse breast cancer resistance protein (bcrp1/abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by p-glycoprotein
-
Allen JD, van Dort SC, Buitelaar M, van Tellingen O, Schinkel AH. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein. Cancer Res 2003;63: 1339-44.
-
(2003)
Cancer Res
, vol.63
, pp. 1339-1344
-
-
Allen, J.D.1
Van Dort, S.C.2
Buitelaar, M.3
Van Tellingen, O.4
Schinkel, A.H.5
-
41
-
-
0036206470
-
Delineating the contribution of secretory transporters in the efflux of etoposide using madin-darby canine kidney (mdck) cells overexpressing p-glycoprotein (pgp), multidrug resistanceassociated protein (mrp1), and canalicular multispecific organic anion transporter (cmoat
-
Guo A, Marinaro W, Hu P, Sinko PJ. Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistanceassociated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT). Drug Metab Dispos 2002;30: 457-63.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 457-463
-
-
Guo, A.1
Marinaro, W.2
Hu, P.3
Sinko, P.J.4
-
42
-
-
0345299165
-
Drug resistance and atp-dependent conjugate transport mediated by the apikal multidrug resistance protein, mrp2, permanently expressed in human and canine cells
-
Cui Y, Konig J, Buchholz JK, Spring H, Leier I, Keppler D. Drug resistance and ATP-dependent conjugate transport mediated by the apikal multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol Pharmacol 1999;55: 929-37.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 929-937
-
-
Cui, Y.1
Konig, J.2
Buchholz, J.K.3
Spring, H.4
Leier, I.5
Keppler, D.6
-
43
-
-
13044294031
-
Mrp3, an organic anion transporter able to transport anti-cancer drugs
-
Kool M, van der Linden M, de Haas M, Scheffer GL, de Vree JM, Smith AJ, et al. MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Nat Acad Sci USA 1999;96: 6914-9.
-
(1999)
Proc Nat Acad Sci USA
, vol.96
, pp. 6914-6919
-
-
Kool, M.1
Van Der Linden, M.2
De Haas, M.3
Scheffer, G.L.4
De Vree, J.M.5
Smith, A.J.6
-
44
-
-
0032494133
-
Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage
-
Wijnholds J, Scheffer GL, van der Valk M, van der Valk P, Beijnen JH, Scheper RJ, et al. Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage. J Exp Med 1998;188: 797-808.
-
(1998)
J Exp Med
, vol.188
, pp. 797-808
-
-
Wijnholds, J.1
Scheffer, G.L.2
Van Der Valk, M.3
Van Der Valk, P.4
Beijnen, J.H.5
Scheper, R.J.6
-
45
-
-
0036246888
-
Resolution of p-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice
-
Stephens RH, O'Neill CA, Bennett J, Humphrey M, Henry B, Rowland M. Resolution of P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice. Br J Pharmacol 2002;135: 2038-46.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 2038-2046
-
-
Stephens, R.H.1
O'Neill, C.A.2
Bennett, J.3
Humphrey, M.4
Henry, B.5
Rowland, M.6
-
46
-
-
74949100493
-
P-glycoprotein (p-gp/abcb1), abcc2, and abcc3 determine the pharmacokinetics of etoposide
-
Lagas JS, Fan L, Wagenaar E, Vlaming MLH, van Tellingen O, Beijnen JH, et al. P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide. Clin Cancer Res 2010;16: 130-40.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 130-140
-
-
Lagas, J.S.1
Fan, L.2
Wagenaar, E.3
Vlaming, M.L.H.4
Van Tellingen, O.5
Beijnen, J.H.6
-
47
-
-
0028009274
-
O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome p450 3a4
-
Relling MV, Nemec J, Schuetz EG, Schuetz JD, Gonzalez FJ, Korzekwa KR. O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Mol Pharmacol 1994;45: 352-8.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 352-358
-
-
Relling, M.V.1
Nemec, J.2
Schuetz, E.G.3
Schuetz, J.D.4
Gonzalez, F.J.5
Korzekwa, K.R.6
-
48
-
-
4143090798
-
Kinetics and regulation of cytochrome p450-mediated etoposide metabolism
-
Zhuo X, Zheng N, Felix CA, Blair IA. Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. Drug Metab Dispos 2004;32: 993-1000.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 993-1000
-
-
Zhuo, X.1
Zheng, N.2
Felix, C.A.3
Blair, I.A.4
-
49
-
-
0032159284
-
A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes
-
Kawashiro T, Yamashita K, Zhao X-J, Koyama E, Tani M, Chiba K, et al. A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes. J Pharmacol Exp Ther 1998;286: 1294-300.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 1294-1300
-
-
Kawashiro, T.1
Yamashita, K.2
Zhao, X.-J.3
Koyama, E.4
Tani, M.5
Chiba, K.6
-
50
-
-
0025350724
-
Role of the semi-quinone free radical of the anti-Tumor agent etoposide (vp-16-213) in the inactivation of single-And double-stranded φx174 dna
-
Mans DRA, Retèl J, van Maanen JMS, Lafleur MVM, van Schaik MA, Pinedo HM, et al. Role of the semi-quinone free radical of the anti-Tumor agent etoposide (VP-16-213) in the inactivation of single-And double-stranded Φ X174 DNA. Br J Cancer 1990;62: 54-60.
-
(1990)
Br J Cancer
, vol.62
, pp. 54-60
-
-
Mans, D.R.A.1
Retèl, J.2
Van Maanen, J.M.S.3
Lafleur, M.V.M.4
Van Schaik, M.A.5
Pinedo, H.M.6
-
51
-
-
0023260691
-
Cytochrome p-450-mediated o-demethylation: A route in the metabolic activation of etoposide (vp-16-213
-
van Maanen JMS, de Vries J, Pappie D, van den Akker E, Lafleur MVM, Retèl J, et al. Cytochrome P-450-mediated O-demethylation: A route in the metabolic activation of etoposide (VP-16-213). Cancer Res 1987;47: 4658-62.
-
(1987)
Cancer Res
, vol.47
, pp. 4658-4662
-
-
Van Maanen, J.M.S.1
De Vries, J.2
Pappie, D.3
Van Den Akker, E.4
Lafleur, M.V.M.5
Retèl, J.6
-
52
-
-
0023158255
-
In vitro metabolism of etoposide (vp-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins
-
Haim N, Nemec J, Roman J, Sinha BK. In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins. Biochem Pharmacol 1987;36: 527-36.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 527-536
-
-
Haim, N.1
Nemec, J.2
Roman, J.3
Sinha, B.K.4
-
53
-
-
0026522710
-
Reactions of glutathione with the catehol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for dna inactivation
-
Mans DR, Lafleur MV, Westmijze EJ, Horn IR, Bets D, Schuurhuis GJ, et al. Reactions of glutathione with the catehol, the ortho-quinone and the semi-quinone free radical of etoposide. Consequences for DNA inactivation. Biochem Pharmacol 1992;43: 1761-8.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1761-1768
-
-
Mans, D.R.1
Lafleur, M.V.2
Westmijze, E.J.3
Horn, I.R.4
Bets, D.5
Schuurhuis, G.J.6
-
54
-
-
33847358669
-
Udp-glucuronosyltransferase 1a1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: Structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics
-
Wen Z, Tallman MN, Ali SY, Smith PC. UDP-glucuronosyltransferase 1A1 Is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: Structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics. Drug Metab Dispos 2007;35: 371-80.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 371-380
-
-
Wen, Z.1
Tallman, M.N.2
Ali, S.Y.3
Smith, P.C.4
-
55
-
-
0037404036
-
Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by udpglucuronosyltransferase 1a1
-
Watanabe Y, Nakajima M, Ohashi N, Kume T, Yokoi T. Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDPglucuronosyltransferase 1A1. Drug Metab Dispos 2003;31: 589-95.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 589-595
-
-
Watanabe, Y.1
Nakajima, M.2
Ohashi, N.3
Kume, T.4
Yokoi, T.5
-
56
-
-
58149164868
-
In vitro-in vivo correlation in p-glycoprotein mediated transport in intestinal absorption
-
Del Amo EM, Heikkinen AT, Mönkkönen J. In vitro-in vivo correlation in p-glycoprotein mediated transport in intestinal absorption. Eur J Pharm Sci 2009;36: 200-11.
-
(2009)
Eur J Pharm Sci
, vol.36
, pp. 200-211
-
-
Del Amo, E.M.1
Heikkinen, A.T.2
Mönkkönen, J.3
-
57
-
-
0034964222
-
Pharmacokinetic and pharmacodynamic implications of p-glycoprotein modulation
-
Matheny CJ, Lamb MW, Brouwer KR, Pollack GM. Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation. Pharmacotherapy 2001;21: 778-96.
-
(2001)
Pharmacotherapy
, vol.21
, pp. 778-796
-
-
Matheny, C.J.1
Lamb, M.W.2
Brouwer, K.R.3
Pollack, G.M.4
-
58
-
-
33644781452
-
Implications of genetic polymorphisms in drug transporters for pharmacotherapy
-
Kerb R. Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett 2006;234: 4-33.
-
(2006)
Cancer Lett
, vol.234
, pp. 4-33
-
-
Kerb, R.1
-
59
-
-
18844409128
-
Predicting drug response and toxicity based on gene polymorphisms
-
Robert J, Le Morvan V, Smith D, Pourquier P, Bonnet J. Predicting drug response and toxicity based on gene polymorphisms. Crit Rev Oncol Hematol 2005;54: 171-96.
-
(2005)
Crit Rev Oncol Hematol
, vol.54
, pp. 171-196
-
-
Robert, J.1
Le Morvan, V.2
Smith, D.3
Pourquier, P.4
Bonnet, J.5
-
60
-
-
84877978307
-
Effect of the c3435t genetic polymorphism in mdr1 on etoposide pharmacokinetics
-
(May 20 suppl;abstr 2500
-
Strother RM, Jones D, Li L, Younger A, Einhorn LH, Williams S, et al. Effect of the C3435T genetic polymorphism in MDR1 on etoposide pharmacokinetics. J Clin Oncol 2008;26 (May 20 suppl;abstr 2500).
-
(2008)
J Clin Oncol
, pp. 26
-
-
Strother, R.M.1
Jones, D.2
Li, L.3
Younger, A.4
Einhorn, L.H.5
Williams, S.6
-
61
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with p-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold H, Brockmoller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000;97: 3473-8.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.4
Brockmoller, J.5
Johne, A.6
-
62
-
-
0036224114
-
Effect of the mutation (c3435t) at exon 26 on the mdr1 gene on expression level of mdr1 messenger ribonucleic acid in duodenal enterocytes of healthy japanese subjects
-
Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T, et al. Effect of the mutation (C3435T) at exon 26 on the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects. Clin Pharmacol Ther 2002;71: 297-303.
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 297-303
-
-
Nakamura, T.1
Sakaeda, T.2
Horinouchi, M.3
Tamura, T.4
Aoyama, N.5
Shirakawa, T.6
-
63
-
-
79954572275
-
Level of evidence for therapeutic drug monitoring for etoposide after oral administration
-
Gerritsen-van Schieveen P, Royer B. Level of evidence for therapeutic drug monitoring for etoposide after oral administration. Fundam Clin Pharmacol 2011;25: 277-82.
-
(2011)
Fundam Clin Pharmacol
, vol.25
, pp. 277-282
-
-
Gerritsen-Van Schieveen, P.1
Royer, B.2
-
64
-
-
0033052358
-
Pharmacokinetics of oral etoposide in patients with hepatocellular carcinoma
-
Aita P, Robieux I, Sorio R, Tumolo S, Corona G, Cannizzaro R, et al. Pharmacokinetics of oral etoposide in patients with hepatocellular carcinoma. Cancer Chemother Pharmacol 1999;43: 287-94.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 287-294
-
-
Aita, P.1
Robieux, I.2
Sorio, R.3
Tumolo, S.4
Corona, G.5
Cannizzaro, R.6
-
65
-
-
0028227610
-
Bioavailability of oral etoposide in gastric cancer
-
Taal BG, Beijnen JH, Teller FG, ten Bokkel Huinink WW, Dubbelman R, Boot H. Bioavailability of oral etoposide in gastric cancer. Eur J Cancer 1994;30A: 420-1.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 420-421
-
-
Taal, B.G.1
Beijnen, J.H.2
Teller, F.G.3
Ten Bokkel Huinink, W.W.4
Dubbelman, R.5
Boot, H.6
-
66
-
-
0032804728
-
Pharmacological analysis of etoposide in elderly patients with lung cancer
-
Ando M, Minami H, Ando Y, Sakai S, Shimono Y, Sugiura S, et al. Pharmacological analysis of etoposide in elderly patients with lung cancer. Clin Cancer Res 1999;5: 1690-5.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1690-1695
-
-
Ando, M.1
Minami, H.2
Ando, Y.3
Sakai, S.4
Shimono, Y.5
Sugiura, S.6
-
67
-
-
0344585230
-
Clinical pharmacological profile of etoposide in the elderly
-
Fijiwara Y, Ohune T, Niitani K, Okusaki K, Sumiyoshi H, Ohashi N. Clinical pharmacological profile of etoposide in the elderly. Proc Am Soc Clin Oncol 1996;15: 174.
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
, pp. 174
-
-
Fijiwara, Y.1
Ohune, T.2
Niitani, K.3
Okusaki, K.4
Sumiyoshi, H.5
Ohashi, N.6
-
68
-
-
84927955766
-
Clinical pharmacological profile of etoposide in elderly patients with lung cancer
-
Miyazaki M, Fujiwara Y, Oguri T, Takahashi T, Ohune T, Sumiyoshi H, et al. Clinical pharmacological profile of etoposide in elderly patients with lung cancer. Asia Pac J Clin Oncol 2005;1: 92-7.
-
(2005)
Asia Pac J Clin Oncol
, vol.1
, pp. 92-97
-
-
Miyazaki, M.1
Fujiwara, Y.2
Oguri, T.3
Takahashi, T.4
Ohune, T.5
Sumiyoshi, H.6
-
69
-
-
22144434701
-
Drug-drug interactions in oncology: Why are they important and can they be minimized?
-
Blower P, de Wit R, Goodin S, Aapro M. Drug-drug interactions in oncology: Why are they important and can they be minimized? Crit Rev Oncol Hematol 2005;55: 117-42.
-
(2005)
Crit Rev Oncol Hematol
, vol.55
, pp. 117-142
-
-
Blower, P.1
De Wit, R.2
Goodin, S.3
Aapro, M.4
-
70
-
-
0036162384
-
Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide
-
Thomas HD, Porter DJ, Bartelink I, Nobbs JR, Cole M, Elliott S, et al. Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide. Br J Clin Pharmacol 2002, 53: 83-91.
-
(2002)
Br J Clin Pharmacol
, vol.53
, pp. 83-91
-
-
Thomas, H.D.1
Porter, D.J.2
Bartelink, I.3
Nobbs, J.R.4
Cole, M.5
Elliott, S.6
-
71
-
-
0031748757
-
High-dose cyclosporin with etoposide-Toxicity and pharmacokinetic interaction in children with solid tumors
-
Bisogno G, Cowie F, Boddy A, Thomas HD, Dick G, Pinkerton CR. High-dose cyclosporin with etoposide-Toxicity and pharmacokinetic interaction in children with solid tumors. Br J Cancer 1998;77: 2304-9.
-
(1998)
Br J Cancer
, vol.77
, pp. 2304-2309
-
-
Bisogno, G.1
Cowie, F.2
Boddy, A.3
Thomas, H.D.4
Dick, G.5
Pinkerton, C.R.6
-
72
-
-
0035065267
-
Effect of hydroxizide on the transport of etoposide in rat small intestine
-
Kan WM, Liu YT, Hsiao CL, Shieh CY, Kuo JH, Huang JD, et al. Effect of hydroxizide on the transport of etoposide in rat small intestine. Anticancer Drugs 2011;12: 267-73.
-
(2011)
Anticancer Drugs
, vol.12
, pp. 267-273
-
-
Kan, W.M.1
Liu, Y.T.2
Hsiao, C.L.3
Shieh, C.Y.4
Kuo, J.H.5
Huang, J.D.6
-
73
-
-
0028801904
-
Inhibition of intestinal p-glycoprotein and effects on etoposide absorption
-
Leu BL, Huang JD. Inhibition of intestinal P-glycoprotein and effects on etoposide absorption. Cancer Chemother Pharmacol 1995;35: 432-6.
-
(1995)
Cancer Chemother Pharmacol
, vol.35
, pp. 432-436
-
-
Leu, B.L.1
Huang, J.D.2
-
74
-
-
78649580065
-
20(S)-Ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: A case for herb-drug interactions
-
Zhang J, Zhou F, Wu X, Gu Y, Ai H, Zheng Y, et al. 20(S)-Ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: A case for herb-drug interactions. Drug Metab Dispos 2010;38: 2179-87.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 2179-2187
-
-
Zhang, J.1
Zhou, F.2
Wu, X.3
Gu, Y.4
Ai, H.5
Zheng, Y.6
-
75
-
-
59449092342
-
Enhanced bioavailability of etoposide after oral or intravenous administration of etoposide with kaempferol in rats
-
Li C, Li X, Choi JS. Enhanced bioavailability of etoposide after oral or intravenous administration of etoposide with kaempferol in rats. Arch Pharm Res 2009;32: 133-8.
-
(2009)
Arch Pharm Res
, vol.32
, pp. 133-138
-
-
Li, C.1
Li, X.2
Choi, J.S.3
-
76
-
-
34248327577
-
Effects of morin on the pharmacokinetics of etoposide in rats
-
Li X, Yun JK, Choi JS. Effects of morin on the pharmacokinetics of etoposide in rats. Biopharm Drug Dispos 2007;28: 151-6.
-
(2007)
Biopharm Drug Dispos
, vol.28
, pp. 151-156
-
-
Li, X.1
Yun, J.K.2
Choi, J.S.3
-
77
-
-
64949088858
-
Effects of quercetin on the pharmacokinetics of etoposide after oral or intravenous administration of etoposide in rats
-
Li X, Choi JS. Effects of quercetin on the pharmacokinetics of Etoposide after oral or intravenous administration of etoposide in rats. Anticancer Res 2009;29: 1411-5.
-
(2009)
Anticancer Res
, vol.29
, pp. 1411-1415
-
-
Li, X.1
Choi, J.S.2
-
78
-
-
56249128976
-
Effects of verapamil on etoposide pharmacokinetics after intravenous and oral administration in rats
-
Piao YJ, Li X, Choi JS. Effects of verapamil on etoposide pharmacokinetics after intravenous and oral administration in rats. Eur J Drug Metab Pharmacokinet 2008;33: 159-64.
-
(2008)
Eur J Drug Metab Pharmacokinet
, vol.33
, pp. 159-164
-
-
Piao, Y.J.1
Li, X.2
Choi, J.S.3
-
79
-
-
0026611746
-
Pharmacologic interactions between the resistance-modifying cyclosporine sdz psc 833 and etoposide (vp 16-213) enhance in vivo cytostatic activity and toxicity
-
Keller RP, Altermatt, HJ, Donatsch P, Zihlmann H, Laissue JA, Hiestand PC. Pharmacologic interactions between the resistance-modifying cyclosporine SDZ PSC 833 and etoposide (VP 16-213) enhance in vivo cytostatic activity and toxicity. Int J Cancer 1992;51: 433-8.
-
(1992)
Int J Cancer
, vol.51
, pp. 433-438
-
-
Keller, R.P.1
Altermatt, H.J.2
Donatsch, P.3
Zihlmann, H.4
Laissue, J.A.5
Hiestand, P.C.6
-
80
-
-
34548565615
-
Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer
-
Peng Yong W, Desai AA, Innocenti F, Ramirez J, Shepard D, Kobayashi K, et al. Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer. Cancer Chemother Pharmacol 2007;60: 811-9.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, pp. 811-819
-
-
Peng Yong, W.1
Desai, A.A.2
Innocenti, F.3
Ramirez, J.4
Shepard, D.5
Kobayashi, K.6
-
81
-
-
0022414303
-
The effect of food and concurent chemotherapy on the bioavailability of oral etoposide
-
Harvey VJ, Slevin ML, Joel SP, Johnston A, Wrigley PFM. The effect of food and concurent chemotherapy on the bioavailability of oral etoposide. Br J Cancer 1985;52: 363-7.
-
(1985)
Br J Cancer
, vol.52
, pp. 363-367
-
-
Harvey, V.J.1
Slevin, M.L.2
Joel, S.P.3
Johnston, A.4
Wrigley, P.F.M.5
-
82
-
-
0036032328
-
Effects of grapefruit juice intake on etoposide bioavailability
-
Reif S, Nicolson MC, Bisset D, Reid M, Kloft C, Jaehde U, et al. Effects of grapefruit juice intake on etoposide bioavailability. Eur J Clin Pharmacol 2002;58: 491-4.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 491-494
-
-
Reif, S.1
Nicolson, M.C.2
Bisset, D.3
Reid, M.4
Kloft, C.5
Jaehde, U.6
-
83
-
-
79955469557
-
Involvment of p-glycoprotein and cyp3a4 in the enhancement of etoposide bioavailability by a piperine analogue
-
Najar IA, Sharma SC, Singh GD, Koul S, Gupta PN, Javed S, et al. Involvment of P-glycoprotein and CYP3A4 in the enhancement of etoposide bioavailability by a piperine analogue. Chem Biol Interact 2011;190: 84-90.
-
(2011)
Chem Biol Interact
, vol.190
, pp. 84-90
-
-
Najar, I.A.1
Sharma, S.C.2
Singh, G.D.3
Koul, S.4
Gupta, P.N.5
Javed, S.6
-
84
-
-
79955070079
-
Effects of oral curcumin on the pharmacokinetics of intravenous and oral etoposide in rats: Possible role of intestinal cyp3a and p-gp inhibition by curcumin
-
Lee CK, Ki SH, Choi JS. Effects of oral curcumin on the pharmacokinetics of intravenous and oral etoposide in rats: possible role of intestinal CYP3A and P-gp inhibition by curcumin. Biopharm Drug Dispos 2011;32: 245-51.
-
(2011)
Biopharm Drug Dispos
, vol.32
, pp. 245-251
-
-
Lee, C.K.1
Ki, S.H.2
Choi, J.S.3
-
85
-
-
0028063076
-
Altered etoposide pharmacokinetics and time to engraftment in pediatric patients undergoing autologous bone marrow transplantation
-
Rodman JH, Murry DJ, Madden T, Santana VM. Altered etoposide pharmacokinetics and time to engraftment in pediatric patients undergoing autologous bone marrow transplantation. J Clin Oncol 1994;12: 2390-7.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2390-2397
-
-
Rodman, J.H.1
Murry, D.J.2
Madden, T.3
Santana, V.M.4
-
86
-
-
0024405310
-
Preformulation study of etoposide: Identification of physicochemical characteristics responsible for the low and erratic oral bioavailability of etoposide
-
Shah JC, Chen JR, Chow D. Preformulation study of etoposide: Identification of physicochemical characteristics responsible for the low and erratic oral bioavailability of etoposide. Pharm Res 1989;6: 408-12.
-
(1989)
Pharm Res
, vol.6
, pp. 408-412
-
-
Shah, J.C.1
Chen, J.R.2
Chow, D.3
-
87
-
-
0025966386
-
The clinical pharmacology of etoposide
-
Slevin ML. The clinical pharmacology of etoposide. Cancer 1991;67: 319-29.
-
(1991)
Cancer
, vol.67
, pp. 319-329
-
-
Slevin, M.L.1
-
88
-
-
0028799840
-
Stability of the i.v. and oral formulations of etoposide in solution
-
Joel SP, Clark PI, Slevin ML. Stability of the i.v. and oral formulations of etoposide in solution. Cancer Chemother Pharmacol 1995;37: 117-24.
-
(1995)
Cancer Chemother Pharmacol
, vol.37
, pp. 117-124
-
-
Joel, S.P.1
Clark, P.I.2
Slevin, M.L.3
-
89
-
-
84927961224
-
A cooperative phase ii study of nk 171 (etoposide) in small cell lung cancer-comparison of results between the intravenous administration and the oral administration
-
Arai R, Kodema N, Tsuruta M, Furuse K, Nishiwaki Y, Nemoto E, et al. A cooperative phase II study of NK 171 (etoposide) in small cell lung cancer-comparison of results between the intravenous administration and the oral administration. Lung Cancer 1986;2: 110.
-
(1986)
Lung Cancer
, vol.2
, pp. 110
-
-
Arai, R.1
Kodema, N.2
Tsuruta, M.3
Furuse, K.4
Nishiwaki, Y.5
Nemoto, E.6
-
90
-
-
0022283510
-
A phase ii study of etoposide (nk171) in small cell lung cancer-comparison of results between intravenous administration and oral administration
-
[Japanese]
-
Furuse K. [A Phase II study of etoposide (NK171) in small cell lung cancer-comparison of results between intravenous administration and oral administration]. [Japanese]. Gan To Kagaku Ryoho 1985;12: 2352-7.
-
(1985)
Gan To Kagaku Ryoho
, vol.12
, pp. 2352-2357
-
-
Furuse, K.1
-
91
-
-
84877934009
-
Comparison of chronic oral and intravenous etoposide administration in combination with cisplatin for the treatment of small cell lung cancer
-
[Abstract]
-
Ohno S, Sugama Y, Sugiyama Y, Kitamura S. Comparison of chronic oral and intravenous etoposide administration in combination with cisplatin for the treatment of small cell lung cancer. [Abstract]. Lung Cancer 1991;7(Suppl 1): 118.
-
(1991)
Lung Cancer
, vol.7
, Issue.SUPPL. 1
, pp. 118
-
-
Ohno, S.1
Sugama, Y.2
Sugiyama, Y.3
Kitamura, S.4
-
92
-
-
0029099869
-
Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: A randomized phase iii study of the cancer and leukemia group b
-
Miller AA, Herndon JE 2nd, Hollis DR, Ellerton J, Langleben A, Richards F 2nd, et al. Schedule dependency of 21-day oral versus 3-day intravenous etoposide in combination with intravenous cisplatin in extensive-stage small-cell lung cancer: A randomized phase III study of the cancer and leukemia group B. J Clin Oncol 1995;13: 1871-9.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1871-1879
-
-
Miller, A.A.1
Herndon II, J.E.2
Hollis, D.R.3
Ellerton, J.4
Langleben, A.5
Richards II, F.6
-
93
-
-
0030608237
-
Comparison of oral etoposide and standard intravenous multidrug chemotherapy for small-cell lung cancer: A stopped multicentre randomised trial
-
Girling DJ. Comparison of oral etoposide and standard intravenous multidrug chemotherapy for small-cell lung cancer: a stopped multicentre randomised trial. Medical Research Council Lung Cancer Working Party. Lancet 1996;348: 563-6.
-
(1996)
Medical Research Council Lung Cancer Working Party. Lancet
, vol.348
, pp. 563-566
-
-
Girling, D.J.1
-
94
-
-
0030946011
-
Five-day oral etoposide treatment for advanced small-cell lung cancer: Randomized comparison with intravenous chemotherapy
-
Souhami RL, Spiro SG, Rudd RM, Ruiz de Elvira MC, James LE, Gower NH, et al. Five-day oral etoposide treatment for advanced small-cell lung cancer: randomized comparison with intravenous chemotherapy. J Natl Cancer Inst 1997, 89: 577-80.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 577-580
-
-
Souhami, R.L.1
Spiro, S.G.2
Rudd, R.M.3
Ruiz De Elvira, M.C.4
James, L.E.5
Gower, N.H.6
-
95
-
-
0036138309
-
The use of oral cytotoxic and cytostatic drugs in cancer treatment
-
Sparreboom A, de Jonge MJA, Verweij J. The use of oral cytotoxic and cytostatic drugs in cancer treatment. Eur J Cancer 2002;38: 18-22.
-
(2002)
Eur J Cancer
, vol.38
, pp. 18-22
-
-
Sparreboom, A.1
De Jonge, M.J.A.2
Verweij, J.3
-
96
-
-
79956365448
-
Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide
-
Zhang T, Chen J, Zhang Y, Shen Q, Pan W. Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide. Eur J Pharm Sci 2011;43: 174-97.
-
(2011)
Eur J Pharm Sci
, vol.43
, pp. 174-197
-
-
Zhang, T.1
Chen, J.2
Zhang, Y.3
Shen, Q.4
Pan, W.5
-
97
-
-
78650020977
-
Preparation and evaluation of a self-emulsifying drug delivery sistem of etoposide-phospholipid complex
-
Wu Z, Guo D, Deng L, Zhang Y, Yang Q, Chen J. Preparation and evaluation of a self-emulsifying drug delivery sistem of etoposide-phospholipid complex. Drug Dev Ind Pharm 2011;37: 103-12.
-
(2011)
Drug Dev Ind Pharm
, vol.37
, pp. 103-112
-
-
Wu, Z.1
Guo, D.2
Deng, L.3
Zhang, Y.4
Yang, Q.5
Chen, J.6
-
98
-
-
84864129092
-
Reformulation of etoposide with solubility-enhancing rubusoside
-
Zhang F, Koh GY, Hollingsworth J, Russo PS, Stout RW, Liu Z. Reformulation of etoposide with solubility-enhancing rubusoside. Int J Pharm 2012;434: 453-9.
-
(2012)
Int J Pharm
, vol.434
, pp. 453-459
-
-
Zhang, F.1
Koh, G.Y.2
Hollingsworth, J.3
Russo, P.S.4
Stout, R.W.5
Liu, Z.6
-
99
-
-
79955034696
-
Enhancing effect of n-octyl-o-sulfate chitosan on etoposide absorption
-
Mo R, Xiao Y, Sun M, Zhang C, Ping Q. Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption. Int J Pharm 2011;409: 38-45.
-
(2011)
Int J Pharm
, vol.409
, pp. 38-45
-
-
Mo, R.1
Xiao, Y.2
Sun, M.3
Zhang, C.4
Ping, Q.5
-
100
-
-
8944232103
-
Etoposide bioavailability after oral administration of the prodrug etoposide phosphate in cancer patients during a phase i study
-
Chabot GG, Armand JP, Terret C, de Forni M, Abigerges D, Winograd B, et al. Etoposide bioavailability after oral administration of the prodrug etoposide phosphate in cancer patients during a phase I study. J Clin Oncol 1996;14: 2020-30.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2020-2030
-
-
Chabot, G.G.1
Armand, J.P.2
Terret, C.3
De Forni, M.4
Abigerges, D.5
Winograd, B.6
-
101
-
-
0028834129
-
Phase i clinical and harmacokinetic study of oral etoposide phosphate
-
Sessa C, Zucchetti M, Cerny T, Pagani O, Cavalli F, De Fusco M, et al. Phase I clinical and harmacokinetic study of oral etoposide phosphate. J Clin Oncol 1995;13: 200-9.
-
(1995)
J Clin Oncol
, vol.13
, pp. 200-209
-
-
Sessa, C.1
Zucchetti, M.2
Cerny, T.3
Pagani, O.4
Cavalli, F.5
De Fusco, M.6
-
102
-
-
8244260093
-
Randomized comparison of etoposide pharmacokinetics after oral etoposide phosphate and oral etoposide
-
de Jong RS, Mulder NH, Uges DRA, Kaul S, Winograd B, Sleijfer DTh, et al. Randomized comparison of etoposide pharmacokinetics after oral etoposide phosphate and oral etoposide. Br J Cancer 1997;75: 1660-6.
-
(1997)
Br J Cancer
, vol.75
, pp. 1660-1666
-
-
De Jong, R.S.1
Mulder, N.H.2
Uges, D.R.A.3
Kaul, S.4
Winograd, B.5
Sleijfer, D.T.H.6
-
103
-
-
34548461683
-
Flat-fixed dosing versus body surface area-based dosing of anticancer drugs in adults: Does it make a difference?
-
Mathijssen RHN, de Jong FA, Loos WJ, van der Bol JM, Verweij J, Sparreboom A. Flat-fixed dosing versus body surface area-based dosing of anticancer drugs in adults: does it make a difference? Oncologist 2007;12: 913-23.
-
(2007)
Oncologist
, vol.12
, pp. 913-923
-
-
Mathijssen, R.H.N.1
De Jong, F.A.2
Loos, W.J.3
Van Der Bol, J.M.4
Verweij, J.5
Sparreboom, A.6
-
104
-
-
0031775809
-
A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children
-
Lowis SP, Price L, Pearson ADJ, Newell DR, Cole M. A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children. Br J Cancer 1998;77: 2318-23.
-
(1998)
Br J Cancer
, vol.77
, pp. 2318-2323
-
-
Lowis, S.P.1
Price, L.2
Pearson, A.D.J.3
Newell, D.R.4
Cole, M.5
-
105
-
-
0033664759
-
Optimization of oral etoposide dosage in elderly patients with non-hodgkin's lymphoma using the fraction of dose absorbed measured for each patient
-
El-Yazigi A, Ezzat A, Berry J, Raines DA, Yusuf A, Al-Rawithi S, et al. Optimization of oral etoposide dosage in elderly patients with non-Hodgkin's lymphoma using the fraction of dose absorbed measured for each patient. J Clin Pharmacol 2000;40: 153-60.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 153-160
-
-
El-Yazigi, A.1
Ezzat, A.2
Berry, J.3
Raines, D.A.4
Yusuf, A.5
Al-Rawithi, S.6
-
106
-
-
0028817911
-
Limited sampling models for reliable estimation of etoposide area under the curve
-
Holz JB, Köppler H, Schmidt L, Fritsch HW, Pflüger KH, Jungclas H. Limited sampling models for reliable estimation of etoposide area under the curve. Eur J Cancer 1995;31A: 1794-8.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1794-1798
-
-
Holz, J.B.1
Köppler, H.2
Schmidt, L.3
Fritsch, H.W.4
Pflüger, K.H.5
Jungclas, H.6
-
107
-
-
0027164659
-
A limited sampling model for the pharmacokinetics of etoposide given orally
-
Gentili D, Zucchetti M, Torri V, Sessa C, de Jong J, Cavalli F, et al. A limited sampling model for the pharmacokinetics of etoposide given orally. Cancer Chemother Pharmacol 1993;32: 482-6.
-
(1993)
Cancer Chemother Pharmacol
, vol.32
, pp. 482-486
-
-
Gentili, D.1
Zucchetti, M.2
Torri, V.3
Sessa, C.4
De Jong, J.5
Cavalli, F.6
-
108
-
-
0028798952
-
Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer
-
Millward MJ, Newell DR, Yuen K, Matthews JP, Balmanno K, Charlton CJ, et al. Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer. Cancer Chemother Pharmacol 1995;37: 161-7.
-
(1995)
Cancer Chemother Pharmacol
, vol.37
, pp. 161-167
-
-
Millward, M.J.1
Newell, D.R.2
Yuen, K.3
Matthews, J.P.4
Balmanno, K.5
Charlton, C.J.6
-
109
-
-
0028873019
-
Clinical and pharmacologic analysis of hyperfractionated daily oral etoposide
-
Minami H, Ando Y, Sakai S, Shimokata K. Clinical and pharmacologic analysis of hyperfractionated daily oral etoposide. J Clin Oncol 1995;13: 191-9.
-
(1995)
J Clin Oncol
, vol.13
, pp. 191-199
-
-
Minami, H.1
Ando, Y.2
Sakai, S.3
Shimokata, K.4
-
110
-
-
0032982127
-
A limited-sampling strategy for estimation of etoposide pharmacokinetics in cancer patients
-
Tranchand B, Amsellem C, Chatelut E, Freyer G, Iliadis A, Ligneau B, et al. A limited-sampling strategy for estimation of etoposide pharmacokinetics in cancer patients. Cancer Chemother Pharmacol 1999;43: 316-22.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, pp. 316-322
-
-
Tranchand, B.1
Amsellem, C.2
Chatelut, E.3
Freyer, G.4
Iliadis, A.5
Ligneau, B.6
-
111
-
-
33749028696
-
Etoposide pharmacokinetics in children treated for acute myeloid leukaemia
-
Palle J, Frost BM, Gustafsson G, Hellebostad M, Kanerva J, Liliemark E. Etoposide pharmacokinetics in children treated for acute myeloid leukaemia. Anticancer Drugs 2006;17: 1087-94.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 1087-1094
-
-
Palle, J.1
Frost, B.M.2
Gustafsson, G.3
Hellebostad, M.4
Kanerva, J.5
Liliemark, E.6
-
112
-
-
0027421049
-
Etoposide pharmacokinetics: The development and prospective validation of a dosing equation
-
Lowis SP, Pearson ADJ, Newell DR, Cole M. Etoposide pharmacokinetics: the development and prospective validation of a dosing equation. Cancer Res 1993;53: 4881-9.
-
(1993)
Cancer Res
, vol.53
, pp. 4881-4889
-
-
Lowis, S.P.1
Pearson, A.D.J.2
Newell, D.R.3
Cole, M.4
-
113
-
-
0029789372
-
Therapeutic drug monitoring in 21-day oral etoposide treatment for lung cancer
-
Ando Y, Minami H, Saka H, Ando M, Sakai S, Shimokata K. Therapeutic drug monitoring in 21-day oral etoposide treatment for lung cancer. Jpn J Cancer Res 1996;87: 856-61.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 856-861
-
-
Ando, Y.1
Minami, H.2
Saka, H.3
Ando, M.4
Sakai, S.5
Shimokata, K.6
-
114
-
-
0031775809
-
A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children
-
Lowis SP, Price L, Pearson ADJ, Newell DR, Cole M. A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children. Br J Cancer 1998;77: 2318-23.
-
(1998)
Br J Cancer
, vol.77
, pp. 2318-2323
-
-
Lowis, S.P.1
Price, L.2
Pearson, A.D.J.3
Newell, D.R.4
Cole, M.5
-
115
-
-
0025836658
-
Population pharmacokinetics: Theory and practice
-
Aarons L. Population pharmacokinetics: theory and practice. Br J Clin Pharmacol 1991;31: 669-70.
-
(1991)
Br J Clin Pharmacol
, vol.31
, pp. 669-670
-
-
Aarons, L.1
-
116
-
-
6844250116
-
Population pharmacokinetics of total and unbound etoposide
-
Nguyen I, Chatelut E, Chevreau C, Tranchand B, Lochon I, Bachaud JM, et al. Population pharmacokinetics of total and unbound etoposide. Cancer Chemother Pharmacol 1998;41: 125-32.
-
(1998)
Cancer Chemother Pharmacol
, vol.41
, pp. 125-132
-
-
Nguyen, I.1
Chatelut, E.2
Chevreau, C.3
Tranchand, B.4
Lochon, I.5
Bachaud, J.M.6
-
117
-
-
0035514648
-
Population pharmacokinetics and pharmacodynamics of oral etoposide
-
Toffoli G, Corona G, Sorio R, Robieux I, Basso B, Colussi AM, et al. Population pharmacokinetics and pharmacodynamics of oral etoposide. J Clin Pharmacol 2001;52: 511-9.
-
(2001)
J Clin Pharmacol
, vol.52
, pp. 511-519
-
-
Toffoli, G.1
Corona, G.2
Sorio, R.3
Robieux, I.4
Basso, B.5
Colussi, A.M.6
-
118
-
-
0036890583
-
Population pharmacokientics of etoposide: Application to therapeutic drug monitoring
-
Ciccolini J, Monjanel-Mouterde S, Bun SS, Blanc C, Duffaud F, Favre R, et al. Population pharmacokientics of etoposide: application to therapeutic drug monitoring. Ther Drug Monit 2002;24: 709-14.
-
(2002)
Ther Drug Monit
, vol.24
, pp. 709-714
-
-
Ciccolini, J.1
Monjanel-Mouterde, S.2
Bun, S.S.3
Blanc, C.4
Duffaud, F.5
Favre, R.6
-
119
-
-
0031035007
-
Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?
-
Nebert DW. Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist? Am J Hum Genet 1997;60: 265-71.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 265-271
-
-
Nebert, D.W.1
-
120
-
-
0027153911
-
Pharmacodynamics of prolonged oral etoposide in patients with advanced non-small-cell lung cancer
-
Miller AA, Tolley EA, Niell HB, Griffin JP, Mauer AM. Pharmacodynamics of prolonged oral etoposide in patients with advanced non-small-cell lung cancer. J Clin Oncol 1993;11: 1179-88.
-
(1993)
J Clin Oncol
, vol.11
, pp. 1179-1188
-
-
Miller, A.A.1
Tolley, E.A.2
Niell, H.B.3
Griffin, J.P.4
Mauer, A.M.5
-
121
-
-
0031744483
-
Therapeutic drug monitoring of 21-day oral etoposide in patients with advanced non-small cell lung cancer
-
Miller AA, Tolley EA, Niell HB. Therapeutic drug monitoring of 21-day oral etoposide in patients with advanced non-small cell lung cancer. Clin Cancer Res 1998;4: 1705-10.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1705-1710
-
-
Miller, A.A.1
Tolley, E.A.2
Niell, H.B.3
|