-
1
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, Lindhout D, Tytgat GN, Jansen PL, Oude Elferink RP, et al. (1995) The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 333:1171-1175.
-
(1995)
N Engl J Med
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
Chowdhury, J.R.2
Bakker, C.3
Gantla, S.4
De Boer, A.5
Oostra, B.A.6
Lindhout, D.7
Tytgat, G.N.8
Jansen, P.L.9
Oude Elferink, R.P.10
-
2
-
-
0028276410
-
Bilirubin UDP-glucuronosyltransferase I is the only relevant bilirubin glucuronidating isoform in man
-
Bosma PJ, Seppen J, Goldhoom B, Bakker C, Oude Elferink RP. Chowdhury JR, Chowdhury NR, and Jansen PL (1994) Bilirubin UDP-glucuronosyltransferase I is the only relevant bilirubin glucuronidating isoform in man. J Biol Chem 269:17960-17964.
-
(1994)
J Biol Chem
, vol.269
, pp. 17960-17964
-
-
Bosma, P.J.1
Seppen, J.2
Goldhoom, B.3
Bakker, C.4
Oude Elferink, R.P.5
Chowdhury, J.R.6
Chowdhury, N.R.7
Jansen, P.L.8
-
3
-
-
0023235581
-
The clinical pharmacology of etoposide and teniposide
-
Clark PI and Slevin ML (1987) The clinical pharmacology of etoposide and teniposide. Clin Pharmacokinet 12:223-252.
-
(1987)
Clin Pharmacokinet
, vol.12
, pp. 223-252
-
-
Clark, P.I.1
Slevin, M.L.2
-
5
-
-
0021801152
-
Metabolic studies of a podophyllotoxin derivative (VP16) in the isolated perfused liver
-
Colombo T, D'Incalci M, Donelli MG, Bartosek I, Benfenati E, Farina P, and Guaitani A (1985) Metabolic studies of a podophyllotoxin derivative (VP16) in the isolated perfused liver. Xenobiotica 15:343-350.
-
(1985)
Xenobiotica
, vol.15
, pp. 343-350
-
-
Colombo, T.1
D'Incalci, M.2
Donelli, M.G.3
Bartosek, I.4
Benfenati, E.5
Farina, P.6
Guaitani, A.7
-
6
-
-
0022608672
-
Pharmacokinetics of etoposide in patients with abnomial renal and hepatic function
-
D'Incalci M, Rossi C, Zucchetti M, Urso R, Cavalli F, Mangioni C, Willems Y, and Sessa C (1986) Pharmacokinetics of etoposide in patients with abnomial renal and hepatic function. Cancer Res 46:2566-2571.
-
(1986)
Cancer Res
, vol.46
, pp. 2566-2571
-
-
D'Incalci, M.1
Rossi, C.2
Zucchetti, M.3
Urso, R.4
Cavalli, F.5
Mangioni, C.6
Willems, Y.7
Sessa, C.8
-
7
-
-
0035209568
-
The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism
-
Fisher MB, Paine MF, Strelevitz TJ, and Wrighton SA (2001) The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism. Drug Metab Rev 33:273-297.
-
(2001)
Drug Metab Rev
, vol.33
, pp. 273-297
-
-
Fisher, M.B.1
Paine, M.F.2
Strelevitz, T.J.3
Wrighton, S.A.4
-
8
-
-
0034966656
-
Thirteen UDP-glucuronosyltransferase gene are encoded at the human UGT1 gene complex locus
-
Gong Q-H, Cho JW, Huang T, Potter C, Gholami N, Basu NK, Kubota S, Carvalho S, Pennington MW, Owens IS, et al. (2001) Thirteen UDP-glucuronosyltransferase gene are encoded at the human UGT1 gene complex locus. Pharmacogenetics 11:357-368.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 357-368
-
-
Gong, Q.-H.1
Cho, J.W.2
Huang, T.3
Potter, C.4
Gholami, N.5
Basu, N.K.6
Kubota, S.7
Carvalho, S.8
Pennington, M.W.9
Owens, I.S.10
-
9
-
-
0028948889
-
Expressed human UGT1.4 protein catalyzed the formation of quaternary ammonium-linked glucuronides
-
Green MD, Bishop WP, and Tephly TR (1995) Expressed human UGT1.4 protein catalyzed the formation of quaternary ammonium-linked glucuronides. Drug Metab Dispos 23:299-302.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 299-302
-
-
Green, M.D.1
Bishop, W.P.2
Tephly, T.R.3
-
10
-
-
0002254766
-
Analysis and characterization of enzyme
-
Hayes AW ed, Raven Press, New York
-
Guengerich FP (1994) Analysis and characterization of enzyme, in Principles and Methods of Toxicology (Hayes AW ed) pp 1259-1313, Raven Press, New York.
-
(1994)
Principles and Methods of Toxicology
, pp. 1259-1313
-
-
Guengerich, F.P.1
-
11
-
-
0001130357
-
Hereditary acholuric jaundice in a new mutant strain of rats
-
Gunn CH (1938) Hereditary acholuric jaundice in a new mutant strain of rats. J Hered 29:137-139.
-
(1938)
J Hered
, vol.29
, pp. 137-139
-
-
Gunn, C.H.1
-
12
-
-
0023919948
-
Identification of etoposide glucuronide as a major metabolite of etoposide in the rat and rabbit
-
Hande K, Anthony L, Hamilton R, Bennett R, Sweetman B, and Branch R (1988) Identification of etoposide glucuronide as a major metabolite of etoposide in the rat and rabbit. Cancer Res 48:1829-1834.
-
(1988)
Cancer Res
, vol.48
, pp. 1829-1834
-
-
Hande, K.1
Anthony, L.2
Hamilton, R.3
Bennett, R.4
Sweetman, B.5
Branch, R.6
-
13
-
-
0021340156
-
Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients
-
Hande KR, Wedlund PJ, Noone RM, Wilkinson GR, Greco FA, and Wolff SN (1984) Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients. Cancer Res 44:379-382.
-
(1984)
Cancer Res
, vol.44
, pp. 379-382
-
-
Hande, K.R.1
Wedlund, P.J.2
Noone, R.M.3
Wilkinson, G.R.4
Greco, F.A.5
Wolff, S.N.6
-
14
-
-
0035076242
-
Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection
-
Hanioka N, Junno H, Tanaka-Kagawa T, Nishimura T, and Ando M (2001a) Determination of UDP-glucuronosyltransferase UGT1A6 activity in human and rat liver microsomes by HPLC with UV detection. J Pharm Biomed Anal 25:65-75.
-
(2001)
J Pharm Biomed Anal
, vol.25
, pp. 65-75
-
-
Hanioka, N.1
Junno, H.2
Tanaka-Kagawa, T.3
Nishimura, T.4
Ando, M.5
-
15
-
-
0034778246
-
Human liver UDP-glucuronasyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothencin
-
Hanioka N, Ozawa S, Junno H, Ando M, Saito Y, and Sawada J (2001b) Human liver UDP-glucuronasyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothencin. Xenobiotica 31:687-699.
-
(2001)
Xenobiotica
, vol.31
, pp. 687-699
-
-
Hanioka, N.1
Ozawa, S.2
Junno, H.3
Ando, M.4
Saito, Y.5
Sawada, J.6
-
16
-
-
0023000393
-
Pharmacokinetics of high dose etoposide (VP 16-213)
-
Holthuis JJ, Postmus PE, Van Oort WJ, Hulshoff B, Verleun H, Sleijfer DT, and Mulder NH (1986) Pharmacokinetics of high dose etoposide (VP 16-213). Eur J Cancer Clin Oncol 22:1149-1155.
-
(1986)
Eur J Cancer Clin Oncol
, vol.22
, pp. 1149-1155
-
-
Holthuis, J.J.1
Postmus, P.E.2
Van Oort, W.J.3
Hulshoff, B.4
Verleun, H.5
Sleijfer, D.T.6
Mulder, N.H.7
-
17
-
-
0026335219
-
Molecular basis of multiple UDP-glucuronosyltransferase isoenzyme deficiencies in the hyperbilirubinemic rat (Gunn rat)
-
Iyanagi T (1991) Molecular basis of multiple UDP-glucuronosyltransferase isoenzyme deficiencies in the hyperbilirubinemic rat (Gunn rat). J Biol Chem 266:24048-24052.
-
(1991)
J Biol Chem
, vol.266
, pp. 24048-24052
-
-
Iyanagi, T.1
-
18
-
-
0030030354
-
Predicting etoposide toxicity: Relationship to organ function and protein binding
-
Joel SP, Shah R, Clark PI, and Slevin ML (1996) Predicting etoposide toxicity: relationship to organ function and protein binding. J Clin Oncol 14:257-267.
-
(1996)
J Clin Oncol
, vol.14
, pp. 257-267
-
-
Joel, S.P.1
Shah, R.2
Clark, P.I.3
Slevin, M.L.4
-
19
-
-
0030221217
-
The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1
-
King CD, Green MD, Rios SR, Coffman BL, Owens IS, Bishop WP, and Tephly TR (1996) The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. Arch Biochem Biophys 332:92-100.
-
(1996)
Arch Biochem Biophys
, vol.332
, pp. 92-100
-
-
King, C.D.1
Green, M.D.2
Rios, S.R.3
Coffman, B.L.4
Owens, I.S.5
Bishop, W.P.6
Tephly, T.R.7
-
21
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, et al. (1997) The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Fournel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
23
-
-
0030030762
-
Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
-
Monaghan G, Ryan M, Seddon R, Hume R, and Burchell B (1996) Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 347:578-581.
-
(1996)
Lancet
, vol.347
, pp. 578-581
-
-
Monaghan, G.1
Ryan, M.2
Seddon, R.3
Hume, R.4
Burchell, B.5
-
24
-
-
0344341029
-
Tissue and organ distribution of etoposide in rat
-
Nakai Y, Natsume N, Irie T, Suwa M, Kametani S, Nakamaki Y, Hashimoto Y, and Ishibashi M (1986) Tissue and organ distribution of etoposide in rat. Drug Metab Pharmacokinet 1:103-122.
-
(1986)
Drug Metab Pharmacokinet
, vol.1
, pp. 103-122
-
-
Nakai, Y.1
Natsume, N.2
Irie, T.3
Suwa, M.4
Kametani, S.5
Nakamaki, Y.6
Hashimoto, Y.7
Ishibashi, M.8
-
25
-
-
0036843498
-
Involvement of multiple UDP-glucuronosytransferase 1A isoforms in glucuronidation of 5-(4′-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes
-
Nakajima M, Sakata N, Ohashi N, Kume T, and Yokoi T (2002) Involvement of multiple UDP-glucuronosytransferase 1A isoforms in glucuronidation of 5-(4′-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes. Drug Metab Dispos 30:1250-1256.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1250-1256
-
-
Nakajima, M.1
Sakata, N.2
Ohashi, N.3
Kume, T.4
Yokoi, T.5
-
26
-
-
0021962185
-
Etoposide (VP-16-213): Current status of an active anticancer drug
-
O'Dwyer PJ, Leyland-Jones B, Alonso MT, Marsoni S, and Wittes RE (1985) Etoposide (VP-16-213): current status of an active anticancer drug. N Engl J Med 312:692-700.
-
(1985)
N Engl J Med
, vol.312
, pp. 692-700
-
-
O'Dwyer, P.J.1
Leyland-Jones, B.2
Alonso, M.T.3
Marsoni, S.4
Wittes, R.E.5
-
27
-
-
0345203500
-
Etoposide
-
Medical Economic Company, Inc., Montvale. NJ
-
Physicians' Desk Reference [PDR] (2000) Etoposide. in Physicians' Desk Reference, 53rd ed., pp 888-889, Medical Economic Company, Inc., Montvale. NJ.
-
(2000)
Physicians' Desk Reference, 53rd Ed.
, pp. 888-889
-
-
-
28
-
-
0028009274
-
O-Demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4
-
Relling MV, Nemec J, Schuetz EG, Schuetz JD, Gonzalez FJ, and Korzekwa KR (1994) O-Demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. Mol Pharmacol 45:352-358.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 352-358
-
-
Relling, M.V.1
Nemec, J.2
Schuetz, E.G.3
Schuetz, J.D.4
Gonzalez, F.J.5
Korzekwa, K.R.6
-
29
-
-
0034534895
-
Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions
-
Ritter JK (2000) Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions. Chem Biol Interact 129:171-193.
-
(2000)
Chem Biol Interact
, vol.129
, pp. 171-193
-
-
Ritter, J.K.1
-
30
-
-
0021688805
-
Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage
-
Ross W, Rowe T, Glisson B, Yalowich J, and Liu L (1984) Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage. Cancer Res 44:5857-5860.
-
(1984)
Cancer Res
, vol.44
, pp. 5857-5860
-
-
Ross, W.1
Rowe, T.2
Glisson, B.3
Yalowich, J.4
Liu, L.5
-
31
-
-
0025744087
-
Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat
-
Sato H, Aono S, Kashiwamata S, and Koiwai O (1991) Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat. Biochem Biophys Res Commun 177:1161-1164.
-
(1991)
Biochem Biophys Res Commun
, vol.177
, pp. 1161-1164
-
-
Sato, H.1
Aono, S.2
Kashiwamata, S.3
Koiwai, O.4
-
32
-
-
0021287609
-
Pharmacokinetics of etoposide (VP16) in children and adolescents with refractory solid tumors
-
Sinkule JA, Hutson P, Hayes FA, Etcubanas E, and Evans W (1984) Pharmacokinetics of etoposide (VP16) in children and adolescents with refractory solid tumors. Cancer Res 44:3109-3113.
-
(1984)
Cancer Res
, vol.44
, pp. 3109-3113
-
-
Sinkule, J.A.1
Hutson, P.2
Hayes, F.A.3
Etcubanas, E.4
Evans, W.5
-
33
-
-
0026011121
-
The chemical and biological route from podophyllotoxin glucoside to etoposide: Ninth Cain memorial award lecture
-
Stähelin HF and von Wartburg A (1991) The chemical and biological route from podophyllotoxin glucoside to etoposide: ninth Cain memorial award lecture. Cancer Res 51:5-15.
-
(1991)
Cancer Res
, vol.51
, pp. 5-15
-
-
Stähelin, H.F.1
Von Wartburg, A.2
-
34
-
-
0028086015
-
Use of etoposide in patients with organ dysfunction: Pharmacokinetic and pharmacodynamic considerations
-
Stewart CF (1994) Use of etoposide in patients with organ dysfunction: pharmacokinetic and pharmacodynamic considerations. Cancer Chemother Pharmacol 34 (Suppl):S76-S83.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, Issue.SUPPL.
-
-
Stewart, C.F.1
-
35
-
-
0034128936
-
Human UDP-glucuronosyltransferase: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferase: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
36
-
-
0036893378
-
Troglitazone glucuranidation in human liver and intestine microsomes: High catalytic activity of UGT1A8 and UGTIA10
-
Watanabe Y. Nakajima M. and Yokoi T (2002) Troglitazone glucuranidation in human liver and intestine microsomes: high catalytic activity of UGT1A8 and UGTIA10. Drug Metab Dispos 30:1462-1469.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1462-1469
-
-
Watanabe, Y.1
Nakajima, M.2
Yokoi, T.3
-
37
-
-
0031864410
-
Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II
-
Yamamoto K, Sato H, Fujiyama Y, Doida Y, and Bamba T (1998) Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II. Biochim Biophys Acta 1406:267-273.
-
(1998)
Biochim Biophys Acta
, vol.1406
, pp. 267-273
-
-
Yamamoto, K.1
Sato, H.2
Fujiyama, Y.3
Doida, Y.4
Bamba, T.5
|