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Volumn 11, Issue 5, 2013, Pages 817-825

Tissue factor non-coagulant signaling - molecular mechanisms and biological consequences with a focus on cell migration and apoptosis

Author keywords

Apoptosis; Cell migration; Cell signaling; Factor VIIa; Protease activated receptor; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 7A; CYTOSKELETON PROTEIN; INTEGRIN; INTERLEUKIN 6; INTERLEUKIN 8; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; THROMBOPLASTIN;

EID: 84877912059     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12156     Document Type: Review
Times cited : (50)

References (100)
  • 1
    • 0024600974 scopus 로고
    • Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade
    • Mackman N, Morrissey JH, Fowler B, Edgington TS. Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade. Biochemistry 1989; 28: 1755-62.
    • (1989) Biochemistry , vol.28 , pp. 1755-1762
    • Mackman, N.1    Morrissey, J.H.2    Fowler, B.3    Edgington, T.S.4
  • 2
    • 0026782822 scopus 로고
    • The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism
    • Zioncheck TF, Roy S, Vehar GA. The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism. J Biol Chem 1992; 267: 3561-4.
    • (1992) J Biol Chem , vol.267 , pp. 3561-3564
    • Zioncheck, T.F.1    Roy, S.2    Vehar, G.A.3
  • 3
    • 84868156108 scopus 로고    scopus 로고
    • Regulation of tissue factor coagulant activity on cell surfaces
    • Rao LV, Pendurthi UR. Regulation of tissue factor coagulant activity on cell surfaces. J Thromb Haemost 2012; 10: 2242-53.
    • (2012) J Thromb Haemost , vol.10 , pp. 2242-2253
    • Rao, L.V.1    Pendurthi, U.R.2
  • 5
    • 0027071674 scopus 로고
    • Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis
    • Mueller BM, Reisfeld RA, Edgington TS, Ruf W. Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci USA 1992; 89: 11832-6.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11832-11836
    • Mueller, B.M.1    Reisfeld, R.A.2    Edgington, T.S.3    Ruf, W.4
  • 6
    • 48749128011 scopus 로고    scopus 로고
    • Tissue factor and protease-activated receptor signaling in cancer
    • Schaffner F, Ruf W. Tissue factor and protease-activated receptor signaling in cancer. Semin Thromb Hemost 2008; 34: 147-53.
    • (2008) Semin Thromb Hemost , vol.34 , pp. 147-153
    • Schaffner, F.1    Ruf, W.2
  • 8
    • 84859789259 scopus 로고    scopus 로고
    • Role of thiol pathways in TF procoagulant regulation
    • Ruf W. Role of thiol pathways in TF procoagulant regulation. Thromb Res 2012; 129(Suppl. 2): S11-12.
    • (2012) Thromb Res , vol.129 , Issue.SUPPL. 2
    • Ruf, W.1
  • 9
    • 84859801846 scopus 로고    scopus 로고
    • Tissue factor encryption and decryption: facts and controversies
    • Rao LV, Kothari H, Pendurthi UR. Tissue factor encryption and decryption: facts and controversies. Thromb Res 2012; 129(Suppl. 2): S13-17.
    • (2012) Thromb Res , vol.129 , Issue.SUPPL. 2
    • Rao, L.V.1    Kothari, H.2    Pendurthi, U.R.3
  • 10
    • 0026650453 scopus 로고
    • Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces
    • Le DT, Rapaport SI, Rao LV. Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem 1992; 267: 15447-54.
    • (1992) J Biol Chem , vol.267 , pp. 15447-15454
    • Le, D.T.1    Rapaport, S.I.2    Rao, L.V.3
  • 12
  • 14
    • 84859802746 scopus 로고    scopus 로고
    • Splice variants of tissue factor and integrin-mediated signaling
    • Srinivasan R, Bogdanov VY. Splice variants of tissue factor and integrin-mediated signaling. Thromb Res 2012; 129(Suppl. 2): S34-7.
    • (2012) Thromb Res , vol.129 , Issue.SUPPL. 2
    • Srinivasan, R.1    Bogdanov, V.Y.2
  • 15
    • 0024386731 scopus 로고
    • Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis
    • Drake TA, Morrissey JH, Edgington TS. Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am J Pathol 1989; 134: 1087-97.
    • (1989) Am J Pathol , vol.134 , pp. 1087-1097
    • Drake, T.A.1    Morrissey, J.H.2    Edgington, T.S.3
  • 16
    • 0025708079 scopus 로고
    • Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody
    • Fleck RA, Rao LV, Rapaport SI, Varki N. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 1990; 59: 421-37.
    • (1990) Thromb Res , vol.59 , pp. 421-437
    • Fleck, R.A.1    Rao, L.V.2    Rapaport, S.I.3    Varki, N.4
  • 17
    • 84857789132 scopus 로고    scopus 로고
    • Tissue factor/TFPI and blood cells
    • Osterud B. Tissue factor/TFPI and blood cells. Thromb Res 2012; 129: 274-8.
    • (2012) Thromb Res , vol.129 , pp. 274-278
    • Osterud, B.1
  • 18
    • 0033782228 scopus 로고    scopus 로고
    • Role of platelet P-selectin and CD40 ligand in the induction of monocytic tissue factor expression
    • Lindmark E, Tenno T, Siegbahn A. Role of platelet P-selectin and CD40 ligand in the induction of monocytic tissue factor expression. Arterioscler Thromb Vasc Biol 2000; 20: 2322-8.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2322-2328
    • Lindmark, E.1    Tenno, T.2    Siegbahn, A.3
  • 19
    • 43749116203 scopus 로고    scopus 로고
    • Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10
    • Christersson C, Johnell M, Siegbahn A. Tissue factor and IL8 production by P-selectin-dependent platelet-monocyte aggregates in whole blood involves phosphorylation of Lyn and is inhibited by IL10. J Thromb Haemost 2008; 6: 986-94.
    • (2008) J Thromb Haemost , vol.6 , pp. 986-994
    • Christersson, C.1    Johnell, M.2    Siegbahn, A.3
  • 20
    • 0027162435 scopus 로고
    • C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor
    • Cermak J, Key NS, Bach RR, Balla J, Jacob HS, Vercellotti GM. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood 1993; 82: 513-20.
    • (1993) Blood , vol.82 , pp. 513-520
    • Cermak, J.1    Key, N.S.2    Bach, R.R.3    Balla, J.4    Jacob, H.S.5    Vercellotti, G.M.6
  • 21
    • 0016790233 scopus 로고
    • The endotoxin-induced coagulant activity of human monocytes
    • Rivers RP, Hathaway WE, Weston WL. The endotoxin-induced coagulant activity of human monocytes. Brit J Haematol 1975; 30:311-16.
    • (1975) Brit J Haematol , vol.30 , pp. 311-316
    • Rivers, R.P.1    Hathaway, W.E.2    Weston, W.L.3
  • 22
    • 0030586940 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB and monocyte chemotactic protein-1 induce human peripheral blood monocytes to express tissue factor
    • Ernofsson M, Siegbahn A. Platelet-derived growth factor-BB and monocyte chemotactic protein-1 induce human peripheral blood monocytes to express tissue factor. Thromb Res 1996; 83: 307-20.
    • (1996) Thromb Res , vol.83 , pp. 307-320
    • Ernofsson, M.1    Siegbahn, A.2
  • 23
    • 0029100932 scopus 로고
    • Regulation of the tissue factor gene
    • Mackman N. Regulation of the tissue factor gene. FASEB J 1995; 9: 883-9.
    • (1995) FASEB J , vol.9 , pp. 883-889
    • Mackman, N.1
  • 24
    • 34249943992 scopus 로고    scopus 로고
    • The intersubject variability of tissue factor mRNA production in human monocytes - relation with the toll-like receptor 4
    • Malarstig A, Siegbahn A. The intersubject variability of tissue factor mRNA production in human monocytes - relation with the toll-like receptor 4. Thromb Res 2007; 120: 407-13.
    • (2007) Thromb Res , vol.120 , pp. 407-413
    • Malarstig, A.1    Siegbahn, A.2
  • 25
    • 33644851056 scopus 로고    scopus 로고
    • Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications
    • Steffel J, Luscher TF, Tanner FC. Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications. Circulation 2006; 113: 722-31.
    • (2006) Circulation , vol.113 , pp. 722-731
    • Steffel, J.1    Luscher, T.F.2    Tanner, F.C.3
  • 26
    • 33644526243 scopus 로고    scopus 로고
    • Tissue factor expression in the morphologic spectrum of vulnerable atherosclerotic plaques
    • van der Wal AC, Li X, de Boer OJ. Tissue factor expression in the morphologic spectrum of vulnerable atherosclerotic plaques. Semin Thromb Hemost 2006; 32: 40-7.
    • (2006) Semin Thromb Hemost , vol.32 , pp. 40-47
    • van der Wal, A.C.1    Li, X.2    de Boer, O.J.3
  • 27
    • 79953321010 scopus 로고    scopus 로고
    • Increased tissue factor expression in diabetes mellitus type 2 monocytes caused by insulin resistance
    • Gerrits AJ, Koekman CA, van Haeften TW, Akkerman JW. Increased tissue factor expression in diabetes mellitus type 2 monocytes caused by insulin resistance. J Thromb Haemost 2011; 9: 873-5.
    • (2011) J Thromb Haemost , vol.9 , pp. 873-875
    • Gerrits, A.J.1    Koekman, C.A.2    van Haeften, T.W.3    Akkerman, J.W.4
  • 28
    • 84857788785 scopus 로고    scopus 로고
    • Thrombosis and cancer: 40 years of research
    • Donati MB, Lorenzet R. Thrombosis and cancer: 40 years of research. Thromb Res 2012; 129: 348-52.
    • (2012) Thromb Res , vol.129 , pp. 348-352
    • Donati, M.B.1    Lorenzet, R.2
  • 29
    • 0038633316 scopus 로고    scopus 로고
    • Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects
    • de Jonge E, Friederich PW, Vlasuk GP, Rote WE, Vroom MB, Levi M, van der Poll T. Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects. Clin Diagn Lab Immunol 2003; 10: 495-7.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 495-497
    • de Jonge, E.1    Friederich, P.W.2    Vlasuk, G.P.3    Rote, W.E.4    Vroom, M.B.5    Levi, M.6    van der Poll, T.7
  • 31
    • 0001495165 scopus 로고
    • Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque
    • Wilcox JN, Smith KM, Schwartz SM, Gordon D. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 1989; 86: 2839-43.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2839-2843
    • Wilcox, J.N.1    Smith, K.M.2    Schwartz, S.M.3    Gordon, D.4
  • 32
    • 0033999142 scopus 로고    scopus 로고
    • Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes
    • Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet JM, Tedgui A. Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 2000; 101: 841-3.
    • (2000) Circulation , vol.101 , pp. 841-843
    • Mallat, Z.1    Benamer, H.2    Hugel, B.3    Benessiano, J.4    Steg, P.G.5    Freyssinet, J.M.6    Tedgui, A.7
  • 34
    • 84863442507 scopus 로고    scopus 로고
    • The impact of blood coagulability on atherosclerosis and cardiovascular disease
    • Loeffen R, Spronk HM, ten Cate H. The impact of blood coagulability on atherosclerosis and cardiovascular disease. J Thromb Haemost 2012; 10: 1207-16.
    • (2012) J Thromb Haemost , vol.10 , pp. 1207-1216
    • Loeffen, R.1    Spronk, H.M.2    ten Cate, H.3
  • 35
    • 0026775867 scopus 로고
    • Immunohistochemical identification of tissue factor in solid tumors
    • Callander NS, Varki N, Rao LV. Immunohistochemical identification of tissue factor in solid tumors. Cancer 1992; 70: 1194-201.
    • (1992) Cancer , vol.70 , pp. 1194-1201
    • Callander, N.S.1    Varki, N.2    Rao, L.V.3
  • 37
    • 0029991158 scopus 로고    scopus 로고
    • Expression of tissue factor correlates with grade of malignancy in human glioma
    • Hamada K, Kuratsu J, Saitoh Y, Takeshima H, Nishi T, Ushio Y. Expression of tissue factor correlates with grade of malignancy in human glioma. Cancer 1996; 77: 1877-83.
    • (1996) Cancer , vol.77 , pp. 1877-1883
    • Hamada, K.1    Kuratsu, J.2    Saitoh, Y.3    Takeshima, H.4    Nishi, T.5    Ushio, Y.6
  • 38
    • 0034086722 scopus 로고    scopus 로고
    • Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration
    • Ueno T, Toi M, Koike M, Nakamura S, Tominaga T. Tissue factor expression in breast cancer tissues: its correlation with prognosis and plasma concentration. Br J Cancer 2000; 83: 164-70.
    • (2000) Br J Cancer , vol.83 , pp. 164-170
    • Ueno, T.1    Toi, M.2    Koike, M.3    Nakamura, S.4    Tominaga, T.5
  • 39
    • 0029097464 scopus 로고
    • Tissue factor expression correlates with histological grade in human pancreatic cancer
    • Kakkar AK, Lemoine NR, Scully MF, Tebbutt S, Williamson RC. Tissue factor expression correlates with histological grade in human pancreatic cancer. Br J Surg 1995; 82: 1101-4.
    • (1995) Br J Surg , vol.82 , pp. 1101-1104
    • Kakkar, A.K.1    Lemoine, N.R.2    Scully, M.F.3    Tebbutt, S.4    Williamson, R.C.5
  • 40
    • 33947308915 scopus 로고    scopus 로고
    • Plasma tissue factor antigen in localized prostate cancer: distribution, clinical significance and correlation with haemostatic activation markers
    • Langer F, Chun FK, Amirkhosravi A, Friedrich M, Leuenroth S, Eifrig B, Bokemeyer C, Francis JL. Plasma tissue factor antigen in localized prostate cancer: distribution, clinical significance and correlation with haemostatic activation markers. Thromb Haemost 2007; 97: 464-70.
    • (2007) Thromb Haemost , vol.97 , pp. 464-470
    • Langer, F.1    Chun, F.K.2    Amirkhosravi, A.3    Friedrich, M.4    Leuenroth, S.5    Eifrig, B.6    Bokemeyer, C.7    Francis, J.L.8
  • 41
    • 39649105248 scopus 로고    scopus 로고
    • Tissue factor expression correlates with disease-specific survival in patients with node-negative muscle-invasive bladder cancer
    • Patry G, Hovington H, Larue H, Harel F, Fradet Y, Lacombe L. Tissue factor expression correlates with disease-specific survival in patients with node-negative muscle-invasive bladder cancer. Int J Cancer 2008; 122: 1592-7.
    • (2008) Int J Cancer , vol.122 , pp. 1592-1597
    • Patry, G.1    Hovington, H.2    Larue, H.3    Harel, F.4    Fradet, Y.5    Lacombe, L.6
  • 42
    • 84856283500 scopus 로고    scopus 로고
    • The relationship between tissue factor and cancer progression: insights from bench and bedside
    • van Den Berg YW, Osanto S, Reitsma PH, Versteeg HH. The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood 2012; 119: 924-32.
    • (2012) Blood , vol.119 , pp. 924-932
    • Van Den Berg, Y.W.1    Osanto, S.2    Reitsma, P.H.3    Versteeg, H.H.4
  • 43
    • 0027402655 scopus 로고
    • Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation
    • Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood 1993; 81: 734-44.
    • (1993) Blood , vol.81 , pp. 734-744
    • Morrissey, J.H.1    Macik, B.G.2    Neuenschwander, P.F.3    Comp, P.C.4
  • 44
    • 0034670040 scopus 로고    scopus 로고
    • Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis
    • Siegbahn A, Johnell M, Rorsman C, Ezban M, Heldin CH, Ronnstrand L. Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis. Blood 2000; 96: 3452-8.
    • (2000) Blood , vol.96 , pp. 3452-3458
    • Siegbahn, A.1    Johnell, M.2    Rorsman, C.3    Ezban, M.4    Heldin, C.H.5    Ronnstrand, L.6
  • 45
    • 1842474888 scopus 로고    scopus 로고
    • Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration
    • Hjortoe GM, Petersen LC, Albrektsen T, Sorensen BB, Norby PL, Mandal SK, Pendurthi UR, Rao LV. Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 2004; 103: 3029-37.
    • (2004) Blood , vol.103 , pp. 3029-3037
    • Hjortoe, G.M.1    Petersen, L.C.2    Albrektsen, T.3    Sorensen, B.B.4    Norby, P.L.5    Mandal, S.K.6    Pendurthi, U.R.7    Rao, L.V.8
  • 47
    • 73849089144 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases
    • Koizume S, Yokota N, Miyagi E, Hirahara F, Nakamura Y, Sakuma Y, Yoshida A, Kameda Y, Tsuchiya E, Ruf W, Miyagi Y. Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases. Mol Cancer Res 2009; 7: 1928-36.
    • (2009) Mol Cancer Res , vol.7 , pp. 1928-1936
    • Koizume, S.1    Yokota, N.2    Miyagi, E.3    Hirahara, F.4    Nakamura, Y.5    Sakuma, Y.6    Yoshida, A.7    Kameda, Y.8    Tsuchiya, E.9    Ruf, W.10    Miyagi, Y.11
  • 48
    • 77956272974 scopus 로고    scopus 로고
    • Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells
    • Magnus N, Garnier D, Rak J. Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells. Blood 2010; 116: 815-18.
    • (2010) Blood , vol.116 , pp. 815-818
    • Magnus, N.1    Garnier, D.2    Rak, J.3
  • 50
    • 0021359790 scopus 로고
    • Monocytes can be induced by lipopolysaccharide-triggered T lymphocytes to express functional factor VII/VIIa protease activity
    • Tsao BP, Fair DS, Curtiss LK, Edgington TS. Monocytes can be induced by lipopolysaccharide-triggered T lymphocytes to express functional factor VII/VIIa protease activity. J Exp Med 1984; 159: 1042-57.
    • (1984) J Exp Med , vol.159 , pp. 1042-1057
    • Tsao, B.P.1    Fair, D.S.2    Curtiss, L.K.3    Edgington, T.S.4
  • 51
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
    • Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci USA 2000; 97: 5255-60.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 53
    • 0028965560 scopus 로고
    • 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor
    • 2+ signals in J82 cells, transfected COS-1 cells, Madin-Darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor. J Biol Chem 1995; 270: 4650-60.
    • (1995) J Biol Chem , vol.270 , pp. 4650-4660
    • Rottingen, J.A.1    Enden, T.2    Camerer, E.3    Iversen, J.G.4    Prydz, H.5
  • 54
    • 0030729723 scopus 로고    scopus 로고
    • Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase
    • Pendurthi UR, Alok D, Rao LV. Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: up-regulation of poly(A) polymerase. Proc Natl Acad Sci USA 1997; 94: 12598-603.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12598-12603
    • Pendurthi, U.R.1    Alok, D.2    Rao, L.V.3
  • 57
    • 0037189580 scopus 로고    scopus 로고
    • Factor VIIa induces tissue factor-dependent up-regulation of interleukin-8 in a human keratinocyte line
    • Wang X, Gjernes E, Prydz H. Factor VIIa induces tissue factor-dependent up-regulation of interleukin-8 in a human keratinocyte line. J Biol Chem 2002; 277: 23620-6.
    • (2002) J Biol Chem , vol.277 , pp. 23620-23626
    • Wang, X.1    Gjernes, E.2    Prydz, H.3
  • 61
    • 46749091634 scopus 로고    scopus 로고
    • Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells
    • Jiang X, Zhu S, Panetti TS, Bromberg ME. Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells. Thromb Haemost 2008; 100: 127-33.
    • (2008) Thromb Haemost , vol.100 , pp. 127-133
    • Jiang, X.1    Zhu, S.2    Panetti, T.S.3    Bromberg, M.E.4
  • 62
    • 0026058331 scopus 로고
    • Conservation of tissue factor primary sequence among three mammalian species
    • Andrews BS, Rehemtulla A, Fowler BJ, Edgington TS, Mackman N. Conservation of tissue factor primary sequence among three mammalian species. Gene 1991; 98: 265-9.
    • (1991) Gene , vol.98 , pp. 265-269
    • Andrews, B.S.1    Rehemtulla, A.2    Fowler, B.J.3    Edgington, T.S.4    Mackman, N.5
  • 63
    • 0029847188 scopus 로고    scopus 로고
    • 2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active
    • 2+ oscillations in Madin-Darby canine kidney cells only when proteolytically active. J Biol Chem 1996; 271: 29034-42.
    • (1996) J Biol Chem , vol.271 , pp. 29034-29042
    • Camerer, E.1    Rottingen, J.A.2    Iversen, J.G.3    Prydz, H.4
  • 64
    • 0040888915 scopus 로고    scopus 로고
    • Factor VIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain
    • Sorensen BB, Freskgard PO, Nielsen LS, Rao LV, Ezban M, Petersen LC. Factor VIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain. J Biol Chem 1999; 274: 21349-54.
    • (1999) J Biol Chem , vol.274 , pp. 21349-21354
    • Sorensen, B.B.1    Freskgard, P.O.2    Nielsen, L.S.3    Rao, L.V.4    Ezban, M.5    Petersen, L.C.6
  • 65
    • 0344826105 scopus 로고    scopus 로고
    • Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation
    • Dorfleutner A, Ruf W. Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood 2003; 102: 3998-4005.
    • (2003) Blood , vol.102 , pp. 3998-4005
    • Dorfleutner, A.1    Ruf, W.2
  • 66
    • 2442647329 scopus 로고    scopus 로고
    • Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain
    • Ahamed J, Ruf W. Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 2004; 279: 23038-44.
    • (2004) J Biol Chem , vol.279 , pp. 23038-23044
    • Ahamed, J.1    Ruf, W.2
  • 68
    • 77951209407 scopus 로고    scopus 로고
    • Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer
    • Ryden L, Grabau D, Schaffner F, Jonsson PE, Ruf W, Belting M. Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer. Int J Cancer 2010; 126: 2330-40.
    • (2010) Int J Cancer , vol.126 , pp. 2330-2340
    • Ryden, L.1    Grabau, D.2    Schaffner, F.3    Jonsson, P.E.4    Ruf, W.5    Belting, M.6
  • 69
    • 0032498848 scopus 로고    scopus 로고
    • A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280
    • Ott I, Fischer EG, Miyagi Y, Mueller BM, Ruf W. A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280. J Cell Biol 1998; 140: 1241-53.
    • (1998) J Cell Biol , vol.140 , pp. 1241-1253
    • Ott, I.1    Fischer, E.G.2    Miyagi, Y.3    Mueller, B.M.4    Ruf, W.5
  • 70
    • 79151472298 scopus 로고    scopus 로고
    • Tissue factor/FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor death-associated protein kinase 1 (DAPK1)
    • Aberg M, Johnell M, Wickstrom M, Siegbahn A. Tissue factor/FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor death-associated protein kinase 1 (DAPK1). Thromb Res 2011; 127: 141-8.
    • (2011) Thromb Res , vol.127 , pp. 141-148
    • Aberg, M.1    Johnell, M.2    Wickstrom, M.3    Siegbahn, A.4
  • 71
    • 0032488808 scopus 로고    scopus 로고
    • The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex
    • Huang M, Syed R, Stura EA, Stone MJ, Stefanko RS, Ruf W, Edgington TS, Wilson IA. The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J Mol Biol 1998; 275: 873-94.
    • (1998) J Mol Biol , vol.275 , pp. 873-894
    • Huang, M.1    Syed, R.2    Stura, E.A.3    Stone, M.J.4    Stefanko, R.S.5    Ruf, W.6    Edgington, T.S.7    Wilson, I.A.8
  • 72
    • 0035971227 scopus 로고    scopus 로고
    • Role of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2
    • Bergum PW, Cruikshank A, Maki SL, Kelly CR, Ruf W, Vlasuk GP. Role of zymogen and activated factor X as scaffolds for the inhibition of the blood coagulation factor VIIa-tissue factor complex by recombinant nematode anticoagulant protein c2. J Biol Chem 2001; 276: 10063-71.
    • (2001) J Biol Chem , vol.276 , pp. 10063-10071
    • Bergum, P.W.1    Cruikshank, A.2    Maki, S.L.3    Kelly, C.R.4    Ruf, W.5    Vlasuk, G.P.6
  • 73
    • 0037093065 scopus 로고    scopus 로고
    • Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex
    • Francischetti IM, Valenzuela JG, Andersen JF, Mather TN, Ribeiro JM. Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex. Blood 2002; 99: 3602-12.
    • (2002) Blood , vol.99 , pp. 3602-3612
    • Francischetti, I.M.1    Valenzuela, J.G.2    Andersen, J.F.3    Mather, T.N.4    Ribeiro, J.M.5
  • 75
    • 4644312977 scopus 로고    scopus 로고
    • Cross-talk of integrin alpha3beta1 and tissue factor in cell migration
    • Dorfleutner A, Hintermann E, Tarui T, Takada Y, Ruf W. Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. Mol Biol Cell 2004; 15: 4416-25.
    • (2004) Mol Biol Cell , vol.15 , pp. 4416-4425
    • Dorfleutner, A.1    Hintermann, E.2    Tarui, T.3    Takada, Y.4    Ruf, W.5
  • 78
    • 0030045346 scopus 로고    scopus 로고
    • Cell migration: a physically integrated molecular process
    • Lauffenburger DA, Horwitz AF. Cell migration: a physically integrated molecular process. Cell 1996; 84: 359-69.
    • (1996) Cell , vol.84 , pp. 359-369
    • Lauffenburger, D.A.1    Horwitz, A.F.2
  • 79
    • 0031214960 scopus 로고    scopus 로고
    • Involvement of phosphatidylinositide 3′-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis
    • Hooshmand-Rad R, Claesson-Welsh L, Wennstrom S, Yokote K, Siegbahn A, Heldin CH. Involvement of phosphatidylinositide 3′-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis. Exp Cell Res 1997; 234: 434-41.
    • (1997) Exp Cell Res , vol.234 , pp. 434-441
    • Hooshmand-Rad, R.1    Claesson-Welsh, L.2    Wennstrom, S.3    Yokote, K.4    Siegbahn, A.5    Heldin, C.H.6
  • 80
    • 0141483377 scopus 로고    scopus 로고
    • A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis
    • Ge L, Ly Y, Hollenberg M, DeFea K. A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis. J Biol Chem 2003; 278: 34418-26.
    • (2003) J Biol Chem , vol.278 , pp. 34418-34426
    • Ge, L.1    Ly, Y.2    Hollenberg, M.3    DeFea, K.4
  • 81
    • 34547107639 scopus 로고    scopus 로고
    • Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2
    • Zoudilova M, Kumar P, Ge L, Wang P, Bokoch GM, DeFea KA. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J Biol Chem 2007; 282: 20634-46.
    • (2007) J Biol Chem , vol.282 , pp. 20634-20646
    • Zoudilova, M.1    Kumar, P.2    Ge, L.3    Wang, P.4    Bokoch, G.M.5    DeFea, K.A.6
  • 83
    • 84868121665 scopus 로고    scopus 로고
    • Subcellular localization of tissue factor and human coronary artery smooth muscle cell migration
    • Pena E, Arderiu G, Badimon L. Subcellular localization of tissue factor and human coronary artery smooth muscle cell migration. J Thromb Haemost 2012; 10: 2373-82.
    • (2012) J Thromb Haemost , vol.10 , pp. 2373-2382
    • Pena, E.1    Arderiu, G.2    Badimon, L.3
  • 84
    • 73749085142 scopus 로고    scopus 로고
    • Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells
    • Gessler F, Voss V, Dutzmann S, Seifert V, Gerlach R, Kogel D. Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells. Neuroscience 2010; 165: 1312-22.
    • (2010) Neuroscience , vol.165 , pp. 1312-1322
    • Gessler, F.1    Voss, V.2    Dutzmann, S.3    Seifert, V.4    Gerlach, R.5    Kogel, D.6
  • 85
    • 80052318824 scopus 로고    scopus 로고
    • Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620
    • Guo D, Zhou H, Wu Y, Zhou F, Xu G, Wen H, Zhang X. Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620. Tumour Biol 2011; 32: 921-30.
    • (2011) Tumour Biol , vol.32 , pp. 921-930
    • Guo, D.1    Zhou, H.2    Wu, Y.3    Zhou, F.4    Xu, G.5    Wen, H.6    Zhang, X.7
  • 86
    • 0032188909 scopus 로고    scopus 로고
    • Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer
    • Taniguchi T, Kakkar AK, Tuddenham EG, Williamson RC, Lemoine NR. Enhanced expression of urokinase receptor induced through the tissue factor-factor VIIa pathway in human pancreatic cancer. Cancer Res 1998; 58: 4461-7.
    • (1998) Cancer Res , vol.58 , pp. 4461-4467
    • Taniguchi, T.1    Kakkar, A.K.2    Tuddenham, E.G.3    Williamson, R.C.4    Lemoine, N.R.5
  • 88
    • 37549043128 scopus 로고    scopus 로고
    • TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC
    • Siegbahn A, Johnell M, Nordin A, Aberg M, Velling T. TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC. Arterioscler Thromb Vasc Biol 2008; 28: 135-41.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 135-141
    • Siegbahn, A.1    Johnell, M.2    Nordin, A.3    Aberg, M.4    Velling, T.5
  • 89
    • 3543009588 scopus 로고    scopus 로고
    • The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells
    • Wiiger MT, Prydz H. The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells. Thromb Haemost 2004; 92: 13-22.
    • (2004) Thromb Haemost , vol.92 , pp. 13-22
    • Wiiger, M.T.1    Prydz, H.2
  • 91
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 92
    • 0032537609 scopus 로고    scopus 로고
    • Apoptosis and related proteins in different stages of human atherosclerotic plaques
    • Kockx MM, De Meyer GR, Muhring J, Jacob W, Bult H, Herman AG. Apoptosis and related proteins in different stages of human atherosclerotic plaques. Circulation 1998; 97: 2307-15.
    • (1998) Circulation , vol.97 , pp. 2307-2315
    • Kockx, M.M.1    De Meyer, G.R.2    Muhring, J.3    Jacob, W.4    Bult, H.5    Herman, A.G.6
  • 97
    • 41549122407 scopus 로고    scopus 로고
    • Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells
    • Fang J, Gu L, Zhu N, Tang H, Alvarado CS, Zhou M. Tissue factor/FVIIa activates Bcl-2 and prevents doxorubicin-induced apoptosis in neuroblastoma cells. BMC Cancer 2008; 8: 69.
    • (2008) BMC Cancer , vol.8 , pp. 69
    • Fang, J.1    Gu, L.2    Zhu, N.3    Tang, H.4    Alvarado, C.S.5    Zhou, M.6
  • 98
    • 33747122295 scopus 로고    scopus 로고
    • Formation of tissue factor-factor VIIa-factor Xa complex prevents apoptosis in human breast cancer cells
    • Jiang X, Guo YL, Bromberg ME. Formation of tissue factor-factor VIIa-factor Xa complex prevents apoptosis in human breast cancer cells. Thromb Haemost 2006; 96: 196-201.
    • (2006) Thromb Haemost , vol.96 , pp. 196-201
    • Jiang, X.1    Guo, Y.L.2    Bromberg, M.E.3
  • 99
    • 44449100667 scopus 로고    scopus 로고
    • Simvastatin induces apoptosis in human breast cancer cells in a NFkappaB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa
    • Aberg M, Wickstrom M, Siegbahn A. Simvastatin induces apoptosis in human breast cancer cells in a NFkappaB-dependent manner and abolishes the anti-apoptotic signaling of TF/FVIIa and TF/FVIIa/FXa. Thromb Res 2008; 122: 191-202.
    • (2008) Thromb Res , vol.122 , pp. 191-202
    • Aberg, M.1    Wickstrom, M.2    Siegbahn, A.3
  • 100
    • 77956170550 scopus 로고    scopus 로고
    • New insights into apoptosis signaling by Apo2L/TRAIL
    • Gonzalvez F, Ashkenazi A. New insights into apoptosis signaling by Apo2L/TRAIL. Oncogene 2010; 29: 4752-65.
    • (2010) Oncogene , vol.29 , pp. 4752-4765
    • Gonzalvez, F.1    Ashkenazi, A.2


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