A critical role of thrombin/PAR-1 in ADP-induced platelet secretion and the second wave of aggregation

Journal of Thrombosis and Haemostasis

Volumn 11, Issue 5, 2013, Pages 930-940

  Jiang, L ^a   Xu, C ^a   Yu, S ^a   Liu, P ^a   Luo, D ^b   Zhou, Q ^a   Gao, C ^c,d   Hu, H ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b HANGZHOU NORMAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

ADP; PAR 1; PI3K; Platelets; Thrombin

Indexed keywords

1 AMINO 3 CYCLOPROPYLAMINO 7 (4 ISOPROPYLBENZYL) 7H PYRROLO[3,2 F]QUINAZOLINE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; HIRUDIN; INDOMETACIN; INTEGRIN; INTEGRIN ALPHA2B BETA3; PADGEM PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTHROMBIN; THROMBIN; THROMBOXANE A2; UNCLASSIFIED DRUG; WORTMANNIN;

ADULT; ARTICLE; CALCIUM CELL LEVEL; CELL GRANULE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; THROMBOCYTE RICH PLASMA;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BLOOD PLATELETS; CALCIUM; FLOW CYTOMETRY; HUMANS; PLATELET AGGREGATION; RECEPTOR, PAR-1; THROMBIN;

EID: 84877877050     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12168     Document Type: Article

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