PI3-kinase is essential for ADP-stimulated integrin α IIbβ3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin αIIbβ 3-initiated signaling cross-talks

Journal of Biomedical Science

Volumn 12, Issue 6, 2005, Pages 937-948

  Sun, Der Shan ^a   Lo, Szecheng J ^b,c   Tsai, Wei Jern ^d   Lin, Chi Hung ^c   Yu, Mei Shiuan ^a   Chen, Yao Fong ^a   Chang, Hsin Hou ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

ADP; Calcium oscillation; Integrin IIb 3; P2Y receptors; Phosphatidylinositol 3 kinase

Indexed keywords

ADENOSINE DIPHOSPHATE; ALPHA2 INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ARTICLE; CALCIUM SIGNALING; CELL ACTIVATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANDROSTADIENES; BLOOD PLATELETS; CALCIUM; CELL ADHESION; CYTOSKELETON; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FIBRINOGEN; HUMANS; INTEGRINS; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, VIDEO; MODELS, STATISTICAL; OSCILLOMETRY; P-SELECTIN; PEPTIDES; PLASMIDS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RECEPTORS, PURINERGIC P2; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 30544445588     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-005-9016-z     Document Type: Article

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