Extracellular Ca2+ modulates ADP-evoked aggregation through altered agonist degradation: Implications for conditions used to study P2Y receptor activation

British Journal of Haematology

Volumn 153, Issue 1, 2011, Pages 83-91

  Jones, Sarah ^a   Evans, Richard J ^a   Mahaut Smith, Martyn P ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

ADP; Aggregation; Calcium; Ectonucleotidases; Platelets

Indexed keywords

2' DEOXY 6 N METHYLADENOSINE 3',5' BISPHOSPHATE; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; APYRASE; CALCIUM ION; CANGRELOR; ECTONUCLEOTIDASE; NUCLEOTIDASE; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; SODIUM CHLORIDE; THROMBOXANE A2; UNCLASSIFIED DRUG;

ARTICLE; CELL SUSPENSION; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RICH PLASMA;

ADENOSINE; ADENOSINE DIPHOSPHATE; BLOOD PLATELETS; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HUMANS; PLATELET AGGREGATION; RECEPTORS, PURINERGIC P2Y12; THROMBOXANE A2;

EID: 79952576602     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08499.x     Document Type: Article

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