Integration of 1H NMR and UPLC-Q-TOF/MS for a Comprehensive Urinary Metabonomics Study on a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Jia, Hong mei ^a   Feng, Yu fei ^b   Liu, Yue tao ^a   Chang, Xing ^a   Chen, Lin ^a   Zhang, Hong wu ^a   Ding, Gang ^a   Zou, Zhong mei ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DECARBOXYLASE; BIOLOGICAL MARKER; INDOLEAMINE 2,3 DIOXYGENASE; ISOLEUCINE; LEUCINE; PHENYLALANINE; TRYPTOPHAN; TYROSINE; VALINE;

AMINO ACID ANALYSIS; AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC UNPREDICTABLE MILD STRESS; CONTROLLED STUDY; DEPRESSION; DISEASE COURSE; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; METABOLOMICS; METABONOMICS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRESS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACIDS; ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; BEHAVIOR, ANIMAL; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; DEPRESSION; HIPPOCAMPUS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; METABOLIC NETWORKS AND PATHWAYS; METABOLOME; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL;

EID: 84877869228     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063624     Document Type: Article

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