Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: A plasma metabonomics study based on NMR spectroscopy

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 4, 2012, Pages 578-588

  Liu, Xiao Jie ^a   Zhou, Yu Zhi ^a   Li, Zhong Feng ^b   Cui, Jie ^a   Li, Zhen Yu ^a   Gao, Xiao Xia ^a   Sun, Hai Feng ^a   Zhang, Li Zeng ^a   Du, Guan Hua ^c   Qin, Xue Mei ^a  

^a SHANXI UNIVERSITY   (China)

^b CAPITAL NORMAL UNIVERSITY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

CUMS; depression; metabonomics; NMR; plasma; Xiaoyaosan

Indexed keywords

3 HYDROXYBUTYRIC ACID; ALANINE; ANGELICA SINENSIS EXTRACT; ANTIDEPRESSANT AGENT; ATRACTYLODES MACROCEPHALA EXTRACT; BUPLEURUM ROOT EXTRACT; CHINESE DRUG; CHOLINE; FLUOXETINE; GINGER EXTRACT; GLYCOPROTEIN; GLYCYRRHIZA EXTRACT; HIGH DENSITY LIPOPROTEIN; ISOLEUCINE; LEUCINE; LIPID; LOW DENSITY LIPOPROTEIN; MENTHA EXTRACT; N ACETYLGLYCOPROTEIN; PAEONIA ALBA EXTRACT; PAEONIA RADIX; PHOSPHATIDYLCHOLINE; PLANT EXTRACT; PORIA EXTRACT; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINE; VENLAFAXINE; VERY LOW DENSITY LIPOPROTEIN; XIAOYAOSAN;

ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; BEHAVIOR; BLOOD LEVEL; CHEMOMETRIC ANALYSIS; CHRONIC STRESS; CHRONIC UNPREDICTABLE MILD STRESS; CONTROLLED STUDY; DEPRESSION; DISEASE MODEL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; FOOD PREFERENCE; LOCOMOTION; LOW DRUG DOSE; MALE; METABOLITE; METABONOMICS; NONHUMAN; OPEN FIELD TEST; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SYSTEMS BIOLOGY; WEIGHT REDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BIOLOGICAL MARKERS; CHRONIC DISEASE; CYCLOHEXANOLS; DEPRESSION; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FLUOXETINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOMICS; MOTOR ACTIVITY; MULTIVARIATE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; SUCROSE;

EID: 84859107396     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2011.01412.x     Document Type: Article

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