An investigation of the antidepressant action of Xiaoyaosan in rats using ultra performance liquid chromatography-mass spectrometry combined with metabonomics

Phytotherapy Research

Volumn 27, Issue 7, 2013, Pages 1074-1085

  Gao, Xiao Xia ^a   Cui, Jie ^a   Zheng, Xing Yu ^a   Li, Zhen Yu ^a   Choi, Young Hae ^b   Zhou, Yu Zhi ^a   Tian, Jun Sheng ^a   Xing, Jie ^a   Tan, Xiao Jie ^c   Du, Guan Hua ^d   Qin, Xue Mei ^a  

^a SHANXI UNIVERSITY   (China)

^b LEIDEN UNIVERSITY   (Netherlands)

^c Waters Technoledgies   (China)

^d INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

antidepression; chronic unpredictable mild stress; metabonomics; UPLC MS; Xiaoyaosan

Indexed keywords

7 METHYLXANTHINE; ALBIFLORIN; ANGELICA SINENSIS EXTRACT; ANTIDEPRESSANT AGENT; BIOLOGICAL MARKER; BUPLEURUM ROOT EXTRACT; CATECHIN; CHINESE DRUG; CREATININE; DRUG METABOLITE; FERULIC ACID; FLUOXETINE; GALLIC ACID; GLYCYRRHIZA EXTRACT; ISOLIQUIRITIN; LIQUIRITIN; LIQUIRITIN APIOSIDE; PAEONIA RADIX; PAEONIFLORIN; PEPPERMINT; PLANT EXTRACT; PORIA EXTRACT; RHIZOMA ATRACTYLODIS EXTRACT; TYROSINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE; XANTHOSINE; XANTHURENIC ACID; XIAOYAOSAN; ZINGIBERIS RECENS EXTRACT;

AMINO ACID METABOLISM; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CHEMOMETRICS; CHINESE MEDICINE; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG MEGADOSE; DRUG STRUCTURE; ENERGY METABOLISM; INTESTINE FLORA; LOW DRUG DOSE; MALE; MASS SPECTROMETRY; METABOLITE; METABOLOMICS; NONHUMAN; PREDICTION; RAT; STRESS; STRUCTURE ANALYSIS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTIDEPRESSION; CHRONIC UNPREDICTABLE MILD STRESS; METABONOMICS; UPLC-MS; XIAOYAOSAN;

ANIMALS; ANTIDEPRESSIVE AGENTS; BENZOATES; BIOLOGICAL MARKERS; BRIDGED COMPOUNDS; CATECHIN; CHALCONE; CHROMATOGRAPHY, LIQUID; CITRIC ACID; CITRIC ACID CYCLE; COUMARIC ACIDS; CREATINE KINASE; CREATININE; CYCLOHEXANOLS; DRUGS, CHINESE HERBAL; FLAVANONES; FLUOXETINE; GALLIC ACID; GASTROINTESTINAL TRACT; GLUCOSIDES; GLYCINE; HIPPURATES; KETOGLUTARIC ACIDS; KYNURENIC ACID; MALE; MASS SPECTROMETRY; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS; MICROBIOTA; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; TRYPTOPHAN; TYROSINE;

RATTUS; RODENTIA;

EID: 84879914168     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4805     Document Type: Article

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