Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 3, 2011, Pages 533-539

  Su, Zhi Heng ^a   Li, Shu Qi ^b   Zou, Guo An ^c   Yu, Chang Yuan ^b   Sun, Yan Guo ^d   Zhang, Hong Wu ^a   Gu, Ying ^d   Zou, Zhong Mei ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^c XINJIANG TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

^d WATERS CORPORATION   (United States)

Author keywords

Anti depressive effect; Chaihu Shu Gan San; Chronic variable stress model; Traditional Chinese medicines; Ultra performance liquid chromatography time of flight mass spectrometry; Urinary metabonomics

Indexed keywords

3 O METHYLDOPA; ANTIDEPRESSANT AGENT; BIOLOGICAL MARKER; CHAIHU SHU GAN SAN; CHINESE DRUG; FLUOXETINE; FORMIC ACID; KYNURENIC ACID; PANTOTHENIC ACID; PROLINE; UNCLASSIFIED DRUG; XANTHURENIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DETOXIFICATION; ENERGY METABOLISM; FINGER DERMATOGLYPHICS; MALE; METABOLIC PARAMETERS; METABOLITE; NONHUMAN; OSTEOLYSIS; PATHOGENESIS; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; RAT; STRESS; TIME OF FLIGHT MASS SPECTROMETRY; TRYPTOPHAN METABOLISM; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTIDEPRESSIVE AGENTS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHRONIC DISEASE; DEPRESSION; DISEASE MODELS, ANIMAL; MALE; MASS SPECTROMETRY; METABOLOMICS; PLANT EXTRACTS; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL;

EID: 79953226613     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.02.013     Document Type: Article

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