-
1
-
-
33745325861
-
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: Results from the Veterans Administration Genetic Epidemiology Study
-
Abdul-Ghani, M. A., Jenkinson, C. P., Richardson, D. K., Tripathy, D., & DeFronzo, R. A. (2006). Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: Results from the Veterans Administration Genetic Epidemiology Study. Diabetes, 55, 1430-1435.
-
(2006)
Diabetes
, vol.55
, pp. 1430-1435
-
-
Abdul-Ghani, M.A.1
Jenkinson, C.P.2
Richardson, D.K.3
Tripathy, D.4
Defronzo, R.A.5
-
2
-
-
34247637288
-
International Diabetes Federation: A consensus on Type 2 diabetes prevention
-
Alberti, K. G., Zimmet, P., & Shaw, J. (2007). International Diabetes Federation: A consensus on Type 2 diabetes prevention. Diabetic Medicine, 24, 451-463.
-
(2007)
Diabetic Medicine
, vol.24
, pp. 451-463
-
-
Alberti, K.G.1
Zimmet, P.2
Shaw, J.3
-
3
-
-
70350560562
-
Metabolomics applied to diabetes research: Moving from information to knowledge
-
Bain, J. R., Stevens, R. D., Wenner, B. R., Ilkayeva, O., Muoio, D. M., & Newgard, C. B. (2009). Metabolomics applied to diabetes research: Moving from information to knowledge. Diabetes, 58, 2429-2443.
-
(2009)
Diabetes
, vol.58
, pp. 2429-2443
-
-
Bain, J.R.1
Stevens, R.D.2
Wenner, B.R.3
Ilkayeva, O.4
Muoio, D.M.5
Newgard, C.B.6
-
4
-
-
38849159145
-
Metabolomic profiling to develop blood biomarkers for Parkinson's disease
-
Bogdanov, M., Matson, W. R., Wang, L., Matson, T., Saunders-Pullman, R., Bressman, S. S., et al. (2008). Metabolomic profiling to develop blood biomarkers for Parkinson's disease. Brain, 131, 389-396.
-
(2008)
Brain
, vol.131
, pp. 389-396
-
-
Bogdanov, M.1
Matson, W.R.2
Wang, L.3
Matson, T.4
Saunders-Pullman, R.5
Bressman, S.S.6
-
5
-
-
33845575826
-
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
-
Borradaile, N. M., Han, X., Harp, J. D., Gale, S. E., Ory, D. S., & Schaffer, J. E. (2006). Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. Journal of Lipid Research, 47, 2726-2737.
-
(2006)
Journal of Lipid Research
, vol.47
, pp. 2726-2737
-
-
Borradaile, N.M.1
Han, X.2
Harp, J.D.3
Gale, S.E.4
Ory, D.S.5
Schaffer, J.E.6
-
6
-
-
0036913503
-
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
-
Brindle, J. T., Antti, H., Holmes, E., Tranter, G., Nicholson, J. K., Bethell, H. W., et al. (2002). Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nature Medicine, 8, 1439-1444.
-
(2002)
Nature Medicine
, vol.8
, pp. 1439-1444
-
-
Brindle, J.T.1
Antti, H.2
Holmes, E.3
Tranter, G.4
Nicholson, J.K.5
Bethell, H.W.6
-
7
-
-
63249088847
-
Inflammation, insulin resistance, and type 2 diabetes: Back to the future?
-
Cefalu, W. T. (2009). Inflammation, insulin resistance, and type 2 diabetes: Back to the future? Diabetes, 58, 307-308.
-
(2009)
Diabetes
, vol.58
, pp. 307-308
-
-
Cefalu, W.T.1
-
8
-
-
39449129263
-
Practical approach for the identification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information
-
Chen, J., Zhao, X., Fritsche, J., Yin, P., Schmitt-Kopplin, P., Wang, W., et al. (2008). Practical approach for the identification and isomer elucidation of biomarkers detected in a metabonomic study for the discovery of individuals at risk for diabetes by integrating the chromatographic and mass spectrometric information. Analytical Chemistry, 80, 1280-1289.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 1280-1289
-
-
Chen, J.1
Zhao, X.2
Fritsche, J.3
Yin, P.4
Schmitt-Kopplin, P.5
Wang, W.6
-
9
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
Eizirik, D. L., Cardozo, A. K., & Cnop, M. (2008). The role for endoplasmic reticulum stress in diabetes mellitus. Endocrine Reviews, 29, 42-61.
-
(2008)
Endocrine Reviews
, vol.29
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
10
-
-
77954456631
-
-
Eriksson, L., Johansson, E., Kettaneh-Wold, N., & Wold, S. (2001). Multi- and megavariate data analysis principals and applications Umetrics, Umea, Sweden.
-
-
-
-
11
-
-
2542556750
-
Differences in insulin resistance in nondiabetic subjects with isolated impaired glucose tolerance or isolated impaired fasting glucose
-
Festa, A., D'Agostino, R., Jr., Hanley, A. J., Karter, A. J., Saad, M. F., & Haffner, S. M. (2004). Differences in insulin resistance in nondiabetic subjects with isolated impaired glucose tolerance or isolated impaired fasting glucose. Diabetes, 53, 1549-1555.
-
(2004)
Diabetes
, vol.53
, pp. 1549-1555
-
-
Festa, A.1
D'Agostino Jr., R.2
Hanley, A.J.3
Karter, A.J.4
Saad, M.F.5
Haffner, S.M.6
-
12
-
-
52649149131
-
Multi-platform investigation of the metabolome in a leptin receptor defective murine model of type 2 diabetes
-
Gipson, G. T., Tatsuoka, K. S., Ball, R. J., Sokhansanj, B. A., Hansen, M. K., Ryan, T. E., et al. (2008). Multi-platform investigation of the metabolome in a leptin receptor defective murine model of type 2 diabetes. Molecular Biosystems, 4, 1015-1023.
-
(2008)
Molecular Biosystems
, vol.4
, pp. 1015-1023
-
-
Gipson, G.T.1
Tatsuoka, K.S.2
Ball, R.J.3
Sokhansanj, B.A.4
Hansen, M.K.5
Ryan, T.E.6
-
13
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes, E., Loo, R. L., Stamler, J., Bictash, M., Yap, I. K., Chan, Q., et al. (2008a). Human metabolic phenotype diversity and its association with diet and blood pressure. Nature, 453, 396-400.
-
(2008)
Nature
, vol.453
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
Bictash, M.4
Yap, I.K.5
Chan, Q.6
-
14
-
-
50249099816
-
Metabolic phenotyping in health and disease
-
Holmes, E., Wilson, I. D., & Nicholson, J. K. (2008b). Metabolic phenotyping in health and disease. Cell, 134, 714-717.
-
(2008)
Cell
, vol.134
, pp. 714-717
-
-
Holmes, E.1
Wilson, I.D.2
Nicholson, J.K.3
-
15
-
-
62749130523
-
Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride
-
Huo, T., Cai, S., Lu, X., Sha, Y., Yu, M., & Li, F. (2009). Metabonomic study of biochemical changes in the serum of type 2 diabetes mellitus patients after the treatment of metformin hydrochloride. Journal of Pharmaceutical and Biomedical Analysis, 49, 976-982.
-
(2009)
Journal of Pharmaceutical and Biomedical Analysis
, vol.49
, pp. 976-982
-
-
Huo, T.1
Cai, S.2
Lu, X.3
Sha, Y.4
Yu, M.5
Li, F.6
-
16
-
-
38849190556
-
Gut microbiota: A potential new territory for drug targeting
-
Jia, W., Li, H., Zhao, L., & Nicholson, J. K. (2008). Gut microbiota: A potential new territory for drug targeting. Nature Reviews Drug Discovery, 7, 123-129.
-
(2008)
Nature Reviews Drug Discovery
, vol.7
, pp. 123-129
-
-
Jia, W.1
Li, H.2
Zhao, L.3
Nicholson, J.K.4
-
17
-
-
33947216093
-
A comprehensive urinary metabolomic approach for identifying kidney cancer
-
Kind, T., Tolstikov, V., Fiehn, O., & Weiss, R. H. (2007). A comprehensive urinary metabolomic approach for identifying kidney cancer. Analytical Biochemistry, 363, 185-195.
-
(2007)
Analytical Biochemistry
, vol.363
, pp. 185-195
-
-
Kind, T.1
Tolstikov, V.2
Fiehn, O.3
Weiss, R.H.4
-
18
-
-
25844432311
-
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency
-
Koves, T. R., Li, P., An, J., Akimoto, T., Slentz, D., Ilkayeva, O., et al. (2005). Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. The Journal of Biological Chemistry, 280, 33588-33598.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 33588-33598
-
-
Koves, T.R.1
Li, P.2
An, J.3
Akimoto, T.4
Slentz, D.5
Ilkayeva, O.6
-
19
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves, T. R., Ussher, J. R., Noland, R. C., Slentz, D., Mosedale, M., Ilkayeva, O., et al. (2008). Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metabolism, 7, 45-56.
-
(2008)
Cell Metabolism
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
-
20
-
-
7944220068
-
Metabonomics, dietary influences and cultural differences: A 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects
-
Lenz, E. M., Bright, J., Wilson, I. D., Hughes, A., Morrisson, J., Lindberg, H., et al. (2004). Metabonomics, dietary influences and cultural differences: A 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects. Journal of Pharmaceutical and Biomedical Analysis, 36, 841-849.
-
(2004)
Journal of Pharmaceutical and Biomedical Analysis
, vol.36
, pp. 841-849
-
-
Lenz, E.M.1
Bright, J.2
Wilson, I.D.3
Hughes, A.4
Morrisson, J.5
Lindberg, H.6
-
21
-
-
0345490738
-
A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects
-
Lenz, E. M., Bright, J., Wilson, I. D., Morgan, S. R., & Nash, A. F. (2003). A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects. Journal of Pharmaceutical and Biomedical Analysis, 33, 1103-1115.
-
(2003)
Journal of Pharmaceutical and Biomedical Analysis
, vol.33
, pp. 1103-1115
-
-
Lenz, E.M.1
Bright, J.2
Wilson, I.D.3
Morgan, S.R.4
Nash, A.F.5
-
22
-
-
55849144043
-
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury
-
Lewis, G. D., Wei, R., Liu, E., Yang, E., Shi, X., Martinovic, M., et al. (2008). Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury. Journal of Clinical Investigation, 118, 3503-3512.
-
(2008)
Journal of Clinical Investigation
, vol.118
, pp. 3503-3512
-
-
Lewis, G.D.1
Wei, R.2
Liu, E.3
Yang, E.4
Shi, X.5
Martinovic, M.6
-
23
-
-
33845901507
-
Microbial ecology: Human gut microbes associated with obesity
-
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006). Microbial ecology: Human gut microbes associated with obesity. Nature, 444, 1022-1023.
-
(2006)
Nature
, vol.444
, pp. 1022-1023
-
-
Ley, R.E.1
Turnbaugh, P.J.2
Klein, S.3
Gordon, J.I.4
-
24
-
-
41149099000
-
Symbiotic gut microbes modulate human metabolic phenotypes
-
Li, M., Wang, B., Zhang, M., Rantalainen, M., Wang, S., Zhou, H., et al. (2008). Symbiotic gut microbes modulate human metabolic phenotypes. Proceedings of the National Academy of Sciences USA, 105, 2117-2122.
-
(2008)
Proceedings of the National Academy of Sciences USA
, vol.105
, pp. 2117-2122
-
-
Li, M.1
Wang, B.2
Zhang, M.3
Rantalainen, M.4
Wang, S.5
Zhou, H.6
-
25
-
-
0042338519
-
So what's the deal with metabonomics?
-
Lindon, J. C., Holmes, E., & Nicholson, J. K. (2003). So what's the deal with metabonomics? Analytical Chemistry, 75, 384A-391A.
-
(2003)
Analytical Chemistry
, vol.75
-
-
Lindon, J.C.1
Holmes, E.2
Nicholson, J.K.3
-
26
-
-
39149126959
-
1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death
-
Makinen, V. P., Soininen, P., Forsblom, C., Parkkonen, M., Ingman, P., Kaski, K., et al. (2008). 1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death. Molecular Systems Biology, 4, 167.
-
(2008)
Molecular Systems Biology
, vol.4
, pp. 167
-
-
Makinen, V.P.1
Soininen, P.2
Forsblom, C.3
Parkkonen, M.4
Ingman, P.5
Kaski, K.6
-
27
-
-
33847378014
-
Rapid and noninvasive metabonomic characterization of inflammatory bowel disease
-
Marchesi, J. R., Holmes, E., Khan, F., Kochhar, S., Scanlan, P., Shanahan, F., et al. (2007). Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. Journal of Proteome Research, 6, 546-551.
-
(2007)
Journal of Proteome Research
, vol.6
, pp. 546-551
-
-
Marchesi, J.R.1
Holmes, E.2
Khan, F.3
Kochhar, S.4
Scanlan, P.5
Shanahan, F.6
-
28
-
-
47349099600
-
Insulin resistance: A proinflammatory state mediated by lipid-induced signaling dysfunction and involved in atherosclerotic plaque instability
-
Montecucco, F., Steffens, S., & Mach, F. (2008). Insulin resistance: a proinflammatory state mediated by lipid-induced signaling dysfunction and involved in atherosclerotic plaque instability. Mediators of Inflammation, 2008, 767623.
-
(2008)
Mediators of Inflammation
, vol.2008
, pp. 767623
-
-
Montecucco, F.1
Steffens, S.2
Mach, F.3
-
29
-
-
33847645068
-
Impaired fasting glucose and impaired glucose tolerance: Implications for care
-
Nathan, D. M., Davidson, M. B., DeFronzo, R. A., Heine, R. J., Henry, R. R., Pratley, R., et al. (2007). Impaired fasting glucose and impaired glucose tolerance: Implications for care. Diabetes Care, 30, 753-759.
-
(2007)
Diabetes Care
, vol.30
, pp. 753-759
-
-
Nathan, D.M.1
Davidson, M.B.2
Defronzo, R.A.3
Heine, R.J.4
Henry, R.R.5
Pratley, R.6
-
30
-
-
17844404232
-
Gut microorganisms, mammalian metabolism and personalized health care
-
Nicholson, J. K., Holmes, E., & Wilson, I. D. (2005). Gut microorganisms, mammalian metabolism and personalized health care. Nature Reviews. Microbiology, 3, 431-438.
-
(2005)
Nature Reviews. Microbiology
, vol.3
, pp. 431-438
-
-
Nicholson, J.K.1
Holmes, E.2
Wilson, I.D.3
-
31
-
-
54549091125
-
Systems biology: Metabonomics
-
Nicholson, J. K., & Lindon, J. C. (2008). Systems biology: Metabonomics. Nature, 455, 1054-1056.
-
(2008)
Nature
, vol.455
, pp. 1054-1056
-
-
Nicholson, J.K.1
Lindon, J.C.2
-
32
-
-
25644457634
-
Differences in cardiovascular risk factors, insulin resistance, and insulin secretion in individuals with normal glucose tolerance and in subjects with impaired glucose regulation: The Telde Study
-
Novoa, F. J., Boronat, M., Saavedra, P., Diaz-Cremades, J. M., Varillas, V. F., La Roche, F., et al. (2005). Differences in cardiovascular risk factors, insulin resistance, and insulin secretion in individuals with normal glucose tolerance and in subjects with impaired glucose regulation: The Telde Study. Diabetes Care, 28, 2388-2393.
-
(2005)
Diabetes Care
, vol.28
, pp. 2388-2393
-
-
Novoa, F.J.1
Boronat, M.2
Saavedra, P.3
Diaz-Cremades, J.M.4
Varillas, V.F.5
la Roche, F.6
-
33
-
-
52649151321
-
Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity
-
Peter, A., Weigert, C., Staiger, H., Rittig, K., Cegan, A., Lutz, P., et al. (2008). Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity. American Journal of Physiology, Endocrinology and Metabolism, 295, E339-E349.
-
(2008)
American Journal of Physiology, Endocrinology and Metabolism
, vol.295
-
-
Peter, A.1
Weigert, C.2
Staiger, H.3
Rittig, K.4
Cegan, A.5
Lutz, P.6
-
34
-
-
14744285326
-
Impaired glucose tolerance and impaired fasting glucose-a review of diagnosis, clinical implications and management
-
Petersen, J. L., & McGuire, D. K. (2005). Impaired glucose tolerance and impaired fasting glucose-a review of diagnosis, clinical implications and management. Diabetes and Vascular Disease Research, 2, 9-15.
-
(2005)
Diabetes and Vascular Disease Research
, vol.2
, pp. 9-15
-
-
Petersen, J.L.1
McGuire, D.K.2
-
35
-
-
33749512402
-
The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry
-
Plumb, R. S., Johnson, K. A., Rainville, P., Shockcor, J. P., Williams, R., Granger, J. H., et al. (2006). The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry, 20, 2800-2806.
-
(2006)
Rapid Communications in Mass Spectrometry
, vol.20
, pp. 2800-2806
-
-
Plumb, R.S.1
Johnson, K.A.2
Rainville, P.3
Shockcor, J.P.4
Williams, R.5
Granger, J.H.6
-
36
-
-
34247842731
-
A metabolic comparison of urinary changes in type 2 diabetes in mouse, rat and man
-
Salek, R. M., Maguire, M. L., Bentley, E., Rubtsov, D. V., Hough, T., Cheeseman, M., et al. (2007). A metabolic comparison of urinary changes in type 2 diabetes in mouse, rat and man. Physiological Genomics, 29, 99-108.
-
(2007)
Physiological Genomics
, vol.29
, pp. 99-108
-
-
Salek, R.M.1
Maguire, M.L.2
Bentley, E.3
Rubtsov, D.V.4
Hough, T.5
Cheeseman, M.6
-
37
-
-
34250347736
-
Lifestyle intervention in individuals with normal versus impaired glucose tolerance
-
Schafer, S., Kantartzis, K., Machann, J., Venter, C., Niess, A., Schick, F., et al. (2007). Lifestyle intervention in individuals with normal versus impaired glucose tolerance. European Journal of Clinical Investigation, 37, 535-543.
-
(2007)
European Journal of Clinical Investigation
, vol.37
, pp. 535-543
-
-
Schafer, S.1
Kantartzis, K.2
Machann, J.3
Venter, C.4
Niess, A.5
Schick, F.6
-
38
-
-
49449083937
-
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
-
Shaham, O., Wei, R., Wang, T. J., Ricciardi, C., Lewis, G. D., Vasan, R. S., et al. (2008). Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity. Molecular Systems Biology, 4, 214.
-
(2008)
Molecular Systems Biology
, vol.4
, pp. 214
-
-
Shaham, O.1
Wei, R.2
Wang, T.J.3
Ricciardi, C.4
Lewis, G.D.5
Vasan, R.S.6
-
39
-
-
52249095319
-
Metabolomic profiling of dietary-induced insulin resistance in the high fat-fed C57BL/6J mouse
-
Shearer, J., Duggan, G., Weljie, A., Hittel, D. S., Wasserman, D. H., & Vogel, H. J. (2008). Metabolomic profiling of dietary-induced insulin resistance in the high fat-fed C57BL/6J mouse. Diabetes, Obesity and Metabolism, 10, 950-958.
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, pp. 950-958
-
-
Shearer, J.1
Duggan, G.2
Weljie, A.3
Hittel, D.S.4
Wasserman, D.H.5
Vogel, H.J.6
-
40
-
-
29544452318
-
The relation of fasting and 2-h postchallenge plasma glucose concentrations to mortality: Data from the Baltimore Longitudinal Study of Aging with a critical review of the literature
-
Sorkin, J. D., Muller, D. C., Fleg, J. L., & Andres, R. (2005). The relation of fasting and 2-h postchallenge plasma glucose concentrations to mortality: Data from the Baltimore Longitudinal Study of Aging with a critical review of the literature. Diabetes Care, 28, 2626-2632.
-
(2005)
Diabetes Care
, vol.28
, pp. 2626-2632
-
-
Sorkin, J.D.1
Muller, D.C.2
Fleg, J.L.3
Andres, R.4
-
41
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar, A., Poisson, L. M., Rajendiran, T. M., Khan, A. P., Cao, Q., Yu, J., et al. (2009). Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature, 457, 910-914.
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
Khan, A.P.4
Cao, Q.5
Yu, J.6
-
42
-
-
9444249274
-
Palmitate-induced interleukin-6 expression in human coronary artery endothelial cells
-
Staiger, H., Staiger, K., Stefan, N., Wahl, H. G., Machicao, F., Kellerer, M., et al. (2004). Palmitate-induced interleukin-6 expression in human coronary artery endothelial cells. Diabetes, 53, 3209-3216.
-
(2004)
Diabetes
, vol.53
, pp. 3209-3216
-
-
Staiger, H.1
Staiger, K.2
Stefan, N.3
Wahl, H.G.4
Machicao, F.5
Kellerer, M.6
-
43
-
-
41149102818
-
Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans
-
Stefan, N., Peter, A., Cegan, A., Staiger, H., Machann, J., Schick, F., et al. (2008). Low hepatic stearoyl-CoA desaturase 1 activity is associated with fatty liver and insulin resistance in obese humans. Diabetologia, 51, 648-656.
-
(2008)
Diabetologia
, vol.51
, pp. 648-656
-
-
Stefan, N.1
Peter, A.2
Cegan, A.3
Staiger, H.4
Machann, J.5
Schick, F.6
-
44
-
-
0033756185
-
Suppression of systemic, intramuscular, and subcutaneous adipose tissue lipolysis by insulin in humans
-
Stumvoll, M., Jacob, S., Wahl, H. G., Hauer, B., Loblein, K., Grauer, P., et al. (2000). Suppression of systemic, intramuscular, and subcutaneous adipose tissue lipolysis by insulin in humans. Journal of Clinical Endocrinology and Metabolism, 85, 3740-3745.
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, pp. 3740-3745
-
-
Stumvoll, M.1
Jacob, S.2
Wahl, H.G.3
Hauer, B.4
Loblein, K.5
Grauer, P.6
-
45
-
-
48749113401
-
Targeting bile-acid signalling for metabolic diseases
-
Thomas, C., Pellicciari, R., Pruzanski, M., Auwerx, J., & Schoonjans, K. (2008). Targeting bile-acid signalling for metabolic diseases. Nature Reviews Drug Discovery, 7, 678-693.
-
(2008)
Nature Reviews Drug Discovery
, vol.7
, pp. 678-693
-
-
Thomas, C.1
Pellicciari, R.2
Pruzanski, M.3
Auwerx, J.4
Schoonjans, K.5
-
46
-
-
34547674398
-
Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice
-
Toye, A. A., Dumas, M. E., Blancher, C., Rothwell, A. R., Fearnside, J. F., Wilder, S. P., et al. (2007). Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice. Diabetologia, 50, 1867-1879.
-
(2007)
Diabetologia
, vol.50
, pp. 1867-1879
-
-
Toye, A.A.1
Dumas, M.E.2
Blancher, C.3
Rothwell, A.R.4
Fearnside, J.F.5
Wilder, S.P.6
-
47
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., et al. (2009). A core gut microbiome in obese and lean twins. Nature, 457, 480-484.
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
Cantarel, B.L.4
Duncan, A.5
Ley, R.E.6
-
48
-
-
33845874101
-
An obesity-associated gut microbiome with increased capacity for energy harvest
-
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006). An obesity-associated gut microbiome with increased capacity for energy harvest. Nature, 444, 1027-1031.
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
Ley, R.E.2
Mahowald, M.A.3
Magrini, V.4
Mardis, E.R.5
Gordon, J.I.6
-
49
-
-
0036046668
-
Impaired glucose tolerance and impaired fasting glycaemia: The current status on definition and intervention
-
Unwin, N., Shaw, J., Zimmet, P., & Alberti, K. G. (2002). Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention. Diabetic Medicine, 19, 708-723.
-
(2002)
Diabetic Medicine
, vol.19
, pp. 708-723
-
-
Unwin, N.1
Shaw, J.2
Zimmet, P.3
Alberti, K.G.4
-
50
-
-
4644250523
-
The role of analytical sciences in medical systems biology
-
van der Greef, J., Stroobant, P., & van der, H. R. (2004). The role of analytical sciences in medical systems biology. Current Opinion in Chemical Biology, 8, 559-565.
-
(2004)
Current Opinion in Chemical Biology
, vol.8
, pp. 559-565
-
-
van der Greef, J.1
Stroobant, P.2
van Der, H.R.3
-
51
-
-
34247397544
-
Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers
-
van Doorn, M., Vogels, J., Tas, A., van Hoogdalem, E. J., Burggraaf, J., Cohen, A., et al. (2007). Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers. British Journal of Clinical Pharmacology, 63, 562-574.
-
(2007)
British Journal of Clinical Pharmacology
, vol.63
, pp. 562-574
-
-
van Doorn, M.1
Vogels, J.2
Tas, A.3
van Hoogdalem, E.J.4
Burggraaf, J.5
Cohen, A.6
-
52
-
-
0027359236
-
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: Diagnosis by acylcarnitine analysis in blood
-
van Hove, J. L., Zhang, W., Kahler, S. G., Roe, C. R., Chen, Y. T., Terada, N., et al. (1993). Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: diagnosis by acylcarnitine analysis in blood. The American Journal of Human Genetics, 52, 958-966.
-
(1993)
The American Journal of Human Genetics
, vol.52
, pp. 958-966
-
-
van Hove, J.L.1
Zhang, W.2
Kahler, S.G.3
Roe, C.R.4
Chen, Y.T.5
Terada, N.6
-
53
-
-
21644479604
-
Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis
-
Wang, C., Kong, H., Guan, Y., Yang, J., Gu, J., Yang, S., et al. (2005). Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis. Analytical Chemistry, 77, 4108-4116.
-
(2005)
Analytical Chemistry
, vol.77
, pp. 4108-4116
-
-
Wang, C.1
Kong, H.2
Guan, Y.3
Yang, J.4
Gu, J.5
Yang, S.6
-
54
-
-
85044710382
-
Screening for type 2 diabetes: Literature review and economic modelling
-
Waugh, N., Scotland, G., McNamee, P., Gillett, M., Brennan, A., Goyder, E., et al. (2007). Screening for type 2 diabetes: Literature review and economic modelling. Health Technology Assessment, 11, 1-125.
-
(2007)
Health Technology Assessment
, vol.11
, pp. 1-125
-
-
Waugh, N.1
Scotland, G.2
McNamee, P.3
Gillett, M.4
Brennan, A.5
Goyder, E.6
-
55
-
-
2642561229
-
Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB
-
Weigert, C., Brodbeck, K., Staiger, H., Kausch, C., Machicao, F., Haring, H. U., et al. (2004). Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB. The Journal of Biological Chemistry, 279, 23942-23952.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 23942-23952
-
-
Weigert, C.1
Brodbeck, K.2
Staiger, H.3
Kausch, C.4
Machicao, F.5
Haring, H.U.6
-
56
-
-
77954460271
-
-
WHO. (2006). Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: Report of WHO/IDF consultation. WHO Press, Geneva.
-
-
-
-
57
-
-
41149120242
-
Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models
-
Wiklund, S., Johansson, E., Sjostrom, L., Mellerowicz, E. J., Edlund, U., Shockcor, J. P., et al. (2008). Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models. Analytical Chemistry, 80, 115-122.
-
(2008)
Analytical Chemistry
, vol.80
, pp. 115-122
-
-
Wiklund, S.1
Johansson, E.2
Sjostrom, L.3
Mellerowicz, E.J.4
Edlund, U.5
Shockcor, J.P.6
-
58
-
-
33644849267
-
The comparative metabonomics of age-related changes in the urinary composition of male Wistar-derived and Zucker (fa/fa) obese rats
-
Williams, R. E., Lenz, E. M., Rantalainen, M., & Wilson, I. D. (2006a). The comparative metabonomics of age-related changes in the urinary composition of male Wistar-derived and Zucker (fa/fa) obese rats. Molecualr Biosystems, 2, 193-202.
-
(2006)
Molecualr Biosystems
, vol.2
, pp. 193-202
-
-
Williams, R.E.1
Lenz, E.M.2
Rantalainen, M.3
Wilson, I.D.4
-
59
-
-
33644861299
-
A multi-analytical platform approach to the metabonomic analysis of plasma from normal and Zucker (fa/fa) obese rats
-
Williams, R., Lenz, E. M., Wilson, A. J., Granger, J., Wilson, I. D., Major, H., et al. (2006b). A multi-analytical platform approach to the metabonomic analysis of plasma from normal and Zucker (fa/fa) obese rats. Molecular Biosystems, 2, 174-183.
-
(2006)
Molecular Biosystems
, vol.2
, pp. 174-183
-
-
Williams, R.1
Lenz, E.M.2
Wilson, A.J.3
Granger, J.4
Wilson, I.D.5
Major, H.6
-
60
-
-
0032517819
-
Orthogonal signal correction of near-infrared spectra
-
Wold, S., Antti, H., Lindgren, F., & Ohman, J. (1998). Orthogonal signal correction of near-infrared spectra. Chemometrics and Intelligent Laboratory Systems, 44, 175-185.
-
(1998)
Chemometrics and Intelligent Laboratory Systems
, vol.44
, pp. 175-185
-
-
Wold, S.1
Antti, H.2
Lindgren, F.3
Ohman, J.4
-
61
-
-
84939895432
-
Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes
-
Wopereis, S., Rubingh, C. M., van Erk, M. J., Verheij, E. R., van Vliet, T., Cnubben, N. H., et al. (2009). Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. PLoS ONE, 4, e4525.
-
(2009)
PLoS ONE
, vol.4
-
-
Wopereis, S.1
Rubingh, C.M.2
van Erk, M.J.3
Verheij, E.R.4
van Vliet, T.5
Cnubben, N.H.6
-
62
-
-
77954458164
-
-
Yach, D., & Alberti, G. (2003). Screening for type 2 diabetes. Marketing and Dissemination, World Health Organization, Geneva.
-
-
-
-
63
-
-
0034020780
-
Glutamate, a window on liver intermediary metabolism
-
Yang, D., & Brunengraber, H. (2000). Glutamate, a window on liver intermediary metabolism. Journal of Nutrition, 130, 991S-994S.
-
(2000)
Journal of Nutrition
, vol.130
-
-
Yang, D.1
Brunengraber, H.2
-
64
-
-
48749106399
-
Serum metabolic profiling of abnormal savda by liquid chromatography/mass spectrometry
-
Yin, P., Mohemaiti, P., Chen, J., Zhao, X., Lu, X., Yimiti, A., et al. (2008). Serum metabolic profiling of abnormal savda by liquid chromatography/mass spectrometry. Journal of Chromatography B, 871, 322-327.
-
(2008)
Journal of Chromatography B
, vol.871
, pp. 322-327
-
-
Yin, P.1
Mohemaiti, P.2
Chen, J.3
Zhao, X.4
Lu, X.5
Yimiti, A.6
-
65
-
-
52049118795
-
Correlative and quantitative (1)H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats
-
Zhang, S., Nagana Gowda, G. A., Asiago, V., Shanaiah, N., Barbas, C., & Raftery, D. (2008). Correlative and quantitative (1)H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats. Analytical Biochemistry, 383, 76-84.
-
(2008)
Analytical Biochemistry
, vol.383
, pp. 76-84
-
-
Zhang, S.1
Nagana Gowda, G.A.2
Asiago, V.3
Shanaiah, N.4
Barbas, C.5
Raftery, D.6
-
66
-
-
70449450345
-
Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses
-
Zhang, X., Wang, Y., Hao, F., Zhou, X., Han, X., Tang, H., et al. (2009). Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses. Journal of Proteome Research, 8, 5188-5195.
-
(2009)
Journal of Proteome Research
, vol.8
, pp. 5188-5195
-
-
Zhang, X.1
Wang, Y.2
Hao, F.3
Zhou, X.4
Han, X.5
Tang, H.6
-
67
-
-
60849104425
-
Changes of the plasma metabolome during an oral glucose tolerance test: Is there more than glucose to look at?
-
Zhao, X., Peter, A., Fritsche, J., Elcnerova, M., Fritsche, A., Haring, H. U., et al. (2009). Changes of the plasma metabolome during an oral glucose tolerance test: is there more than glucose to look at? American Journal of Physiology, Endocrinology and Metabolism, 296, E384-E393.
-
(2009)
American Journal of Physiology, Endocrinology and Metabolism
, vol.296
-
-
Zhao, X.1
Peter, A.2
Fritsche, J.3
Elcnerova, M.4
Fritsche, A.5
Haring, H.U.6
-
68
-
-
52149124125
-
Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: A urinary metabonomics study based on liquid chromatography-mass spectrometry
-
Zhao, X., Zhang, Y., Meng, X., Yin, P., Deng, C., Chen, J., et al. (2008). Effect of a traditional Chinese medicine preparation Xindi soft capsule on rat model of acute blood stasis: A urinary metabonomics study based on liquid chromatography-mass spectrometry. Journal of Chromatography B, 873, 151-158.
-
(2008)
Journal of Chromatography B
, vol.873
, pp. 151-158
-
-
Zhao, X.1
Zhang, Y.2
Meng, X.3
Yin, P.4
Deng, C.5
Chen, J.6
|