Mechanism of somatic hypermutation at the WA motif by human DNA polymerase n

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 20, 2013, Pages 8146-8151

  Zhao, Ye ^a,b   Gregory, Mark T ^b   Biertümpfel, Christian ^b,d   Hua, Yue Jin ^a   Hanaoka, Fumio ^c   Yang, Wei ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c GAKUSHUIN UNIVERSITY   (Japan)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

A to G transition; Immunoglobulin; P cation stacking

Indexed keywords

DEOXYADENOSINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DNA BASE; DNA DIRECTED DNA POLYMERASE ETA; PURINE; PYRIMIDINE;

ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA SEQUENCE; DNA TEMPLATE; HUMAN; INTERACTIONS WITH DNA; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STABILITY; SOMATIC HYPERMUTATION;

Π-CATION STACKING; A-TO-G TRANSITION; IMMUNOGLOBULIN;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; CATIONS; DEOXYGUANINE NUCLEOTIDES; DNA-DIRECTED DNA POLYMERASE; HUMANS; IMMUNOGLOBULINS; KINETICS; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEIC ACID CONFORMATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 84877867629     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1303126110     Document Type: Article

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