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Volumn 161, Issue 4, 2013, Pages 293-303

Tolerogenic dendritic cells: Key regulators of peripheral tolerance in health and disease

Author keywords

Dendritic cells; Immunotherapy; Maturation; Peripheral tolerance; Regulatory T cells; Tolerance

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 35; TRANSFORMING GROWTH FACTOR BETA; ALPHA INTERFERON; ANISPERIMUS; ARGINASE; B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; CHOLERA TOXIN; COLECALCIFEROL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 5; LYMPHOCYTE ACTIVATION GENE 3; MONOCLONAL ANTIBODY CD3; NITRIC OXIDE; PROSTAGLANDIN E2; PROTEIN; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; SCATTER FACTOR; THYMIC STROMAL LYMPHOPOIETIN; UNCLASSIFIED DRUG; UVOMORULIN; VASOACTIVE INTESTINAL POLYPEPTIDE; VITAMIN D;

EID: 84877846270     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000350328     Document Type: Review
Times cited : (25)

References (81)
  • 1
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice I Morphology, quantitation, tissue distribution
    • Steinman RM, Cohn ZA: Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 1973; 137: 1142-1162
    • (1973) J Exp Med , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 2
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 1998; 392: 245-252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 3
    • 36248965712 scopus 로고    scopus 로고
    • Dendritic cells: Understanding immunogenicity
    • Steinman RM: Dendritic cells: Understanding immunogenicity. Eur J Immunol 2007; 37(suppl 1):S53-S60
    • (2007) Eur J Immunol , vol.37 , Issue.SUPPL. 1
    • Steinman, R.M.1
  • 5
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • Palucka K, Banchereau J: Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012; 12: 265-277
    • (2012) Nat Rev Cancer , vol.12 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 6
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki N, Ho S, Antonenko S, Malefyt RW, Kastelein RA, Bazan F, et al: Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001; 194: 863-869
    • (2001) J Exp Med , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefyt, R.W.4    Kastelein, R.A.5    Bazan, F.6
  • 7
    • 84863073919 scopus 로고    scopus 로고
    • TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9
    • Liu YC, Simmons DP, Li X, Abbott DW, Boom WH, Harding CV: TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9. J Immunol 2012; 188: 1019-1026
    • (2012) J Immunol , vol.188 , pp. 1019-1026
    • Liu, Y.C.1    Simmons, D.P.2    Li, X.3    Abbott, D.W.4    Boom, W.H.5    Harding, C.V.6
  • 8
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM: Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 2002; 196: 1627-1638
    • (2002) J Exp Med , vol.196 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5    Steinman, R.M.6
  • 9
    • 0037099710 scopus 로고    scopus 로고
    • On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity
    • Legge KL, Gregg RK, Maldonado-Lopez R, Li L, Caprio JC, Moser M, et al: On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity. J Exp Med 2002; 196: 217-227
    • (2002) J Exp Med , vol.196 , pp. 217-227
    • Legge, K.L.1    Gregg, R.K.2    Maldonado-Lopez, R.3    Li, L.4    Caprio, J.C.5    Moser, M.6
  • 10
    • 63449108301 scopus 로고    scopus 로고
    • Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
    • Ohnmacht C, Pullner A, King SB, Drexler I, Meier S, Brocker T, et al: Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med 2009; 206: 549-559
    • (2009) J Exp Med , vol.206 , pp. 549-559
    • Ohnmacht, C.1    Pullner, A.2    King, S.B.3    Drexler, I.4    Meier, S.5    Brocker, T.6
  • 11
    • 0036659913 scopus 로고    scopus 로고
    • Antigenbearing immature dendritic cells induce peptide- specific CD8(+) regulatory T cells in vivo in humans
    • Dhodapkar MV, Steinman RM: Antigenbearing immature dendritic cells induce peptide- specific CD8(+) regulatory T cells in vivo in humans. Blood 2002; 100: 174-177
    • (2002) Blood , vol.100 , pp. 174-177
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 12
    • 76249119192 scopus 로고    scopus 로고
    • FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steadystate dendritic cells
    • Schildknecht A, Brauer S, Brenner C, Lahl K, Schild H, Sparwasser T, et al: FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steadystate dendritic cells. Proc Natl Acad Sci USA 2010; 107: 199-203
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 199-203
    • Schildknecht, A.1    Brauer, S.2    Brenner, C.3    Lahl, K.4    Schild, H.5    Sparwasser, T.6
  • 13
    • 0035990373 scopus 로고    scopus 로고
    • IL-12 secreting dendritic cells are required for optimum activation of human secondary lymphoid tissue T cells
    • Rouard H, Marquet J, Leon A, Maison P, Haioun C, Copie-Bergman C, et al: IL-12 secreting dendritic cells are required for optimum activation of human secondary lymphoid tissue T cells. J Immunother 2002; 25: 324-333
    • (2002) J Immunother , vol.25 , pp. 324-333
    • Rouard, H.1    Marquet, J.2    Leon, A.3    Maison, P.4    Haioun, C.5    Copie-Bergman, C.6
  • 14
    • 77954932467 scopus 로고    scopus 로고
    • Programming dendritic cells to induce T(H)2 and tolerogenic responses
    • Pulendran B, Tang H, Manicassamy S: Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Immunol 2010; 11: 647-655
    • (2010) Nat Immunol , vol.11 , pp. 647-655
    • Pulendran, B.1    Tang, H.2    Manicassamy, S.3
  • 15
    • 84874038489 scopus 로고    scopus 로고
    • Therapeutic potential of semi-mature dendritic cells for tolerance induction
    • Lutz MB: Therapeutic potential of semi-mature dendritic cells for tolerance induction. Front Immunol 2012; 3: 123
    • (2012) Front Immunol , vol.3 , pp. 123
    • Lutz, M.B.1
  • 16
    • 13944260898 scopus 로고    scopus 로고
    • Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
    • Sporri R, Reis e Sousa C: Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol 2005; 6: 163-170
    • (2005) Nat Immunol , vol.6 , pp. 163-170
    • Sporri, R.1    Reise Sousa, C.2
  • 17
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • Menges M, Rossner S, Voigtlander C, Schindler H, Kukutsch NA, Bogdan C, et al: Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J Exp Med 2002; 195: 15-21
    • (2002) J Exp Med , vol.195 , pp. 15-21
    • Menges, M.1    Rossner, S.2    Voigtlander, C.3    Schindler, H.4    Kukutsch, N.A.5    Bogdan, C.6
  • 18
    • 33745712871 scopus 로고    scopus 로고
    • Reis e Sousa C: Dendritic cells in a mature age
    • Reis e Sousa C: Dendritic cells in a mature age. Nat Rev Immunol 2006; 6: 476-483
    • (2006) Nat Rev Immunol , vol.6 , pp. 476-483
  • 20
    • 0036297943 scopus 로고    scopus 로고
    • Tolerogenic antigen-presenting cells
    • Munn DH: Tolerogenic antigen-presenting cells. Ann NY Acad Sci 2002; 961: 343-345
    • (2002) Ann NY Acad Sci , vol.961 , pp. 343-345
    • Munn, D.H.1
  • 21
    • 84055170530 scopus 로고    scopus 로고
    • Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells
    • Pletinckx K, Dohler A, Pavlovic V, Lutz MB: Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells. Front Immunol 2011; 2: 39
    • (2011) Front Immunol , vol.2 , pp. 39
    • Pletinckx, K.1    Dohler, A.2    Pavlovic, V.3    Lutz, M.B.4
  • 22
    • 58149252418 scopus 로고    scopus 로고
    • Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation
    • Li Q, Guo Z, Xu X, Xia S, Cao X: Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation. Eur J Immunol 2008; 38: 2751- 2761
    • (2008) Eur J Immunol , vol.38 , pp. 2751-2761
    • Li, Q.1    Guo, Z.2    Xu, X.3    Xia, S.4    Cao, X.5
  • 23
    • 84865687882 scopus 로고    scopus 로고
    • Crosstalk of regulatory T cells and tolerogenic dendritic cells prevents contact allergy in subjects with low zone tolerance
    • Luckey U, Schmidt T, Pfender N, Romer M, Lorenz N, Martin SF, et al: Crosstalk of regulatory T cells and tolerogenic dendritic cells prevents contact allergy in subjects with low zone tolerance. J Allergy Clin Immunol 2012; 130: 781.e711-797.e711
    • (2012) J Allergy Clin Immunol , vol.130
    • Luckey, U.1    Schmidt, T.2    Pfender, N.3    Romer, M.4    Lorenz, N.5    Martin, S.F.6
  • 24
    • 84860565845 scopus 로고    scopus 로고
    • Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells
    • Gomez de Aguero M, Vocanson M, Hacini- Rachinel F, Taillardet M, Sparwasser T, Kissenpfennig A, et al: Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells. J Clin Invest 2012; 122: 1700-1711
    • (2012) J Clin Invest , vol.122 , pp. 1700-1711
    • Gomez De Aguero, M.1    Vocanson, M.2    Hacini- Rachinel, F.3    Taillardet, M.4    Sparwasser, T.5    Kissenpfennig, A.6
  • 25
    • 51349131121 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induction by murine hepatic Kupffer cells
    • You Q, Cheng L, Kedl RM, Ju C: Mechanism of T cell tolerance induction by murine hepatic Kupffer cells. Hepatology 2008; 48: 978- 990
    • (2008) Hepatology , vol.48 , pp. 978-990
    • You, Q.1    Cheng, L.2    Kedl, R.M.3    Ju, C.4
  • 27
    • 48649095924 scopus 로고    scopus 로고
    • Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation
    • Muthuswamy R, Urban J, Lee JJ, Reinhart TA, Bartlett D, Kalinski P: Ability of mature dendritic cells to interact with regulatory T cells is imprinted during maturation. Cancer Res 2008; 68: 5972-5978
    • (2008) Cancer Res , vol.68 , pp. 5972-5978
    • Muthuswamy, R.1    Urban, J.2    Lee, J.J.3    Reinhart, T.A.4    Bartlett, D.5    Kalinski, P.6
  • 28
    • 54549096767 scopus 로고    scopus 로고
    • CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    • Hadeiba H, Sato T, Habtezion A, Oderup C, Pan J, Butcher EC: CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat Immunol 2008; 9: 1253-1260
    • (2008) Nat Immunol , vol.9 , pp. 1253-1260
    • Hadeiba, H.1    Sato, T.2    Habtezion, A.3    Oderup, C.4    Pan, J.5    Butcher, E.C.6
  • 29
    • 76249092889 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits IFN-alpha secretion and Th1 costimulation by human plasmacytoid dendritic cells via E-prostanoid 2 and E-prostanoid 4 receptor engagement
    • Fabricius D, Neubauer M, Mandel B, Schutz C, Viardot A, Vollmer A, et al: Prostaglandin E2 inhibits IFN-alpha secretion and Th1 costimulation by human plasmacytoid dendritic cells via E-prostanoid 2 and E-prostanoid 4 receptor engagement. J Immunol 2010; 184: 677-684
    • (2010) J Immunol , vol.184 , pp. 677-684
    • Fabricius, D.1    Neubauer, M.2    Mandel, B.3    Schutz, C.4    Viardot, A.5    Vollmer, A.6
  • 30
    • 78149277909 scopus 로고    scopus 로고
    • How tolerogenic dendritic cells induce regulatory T cells
    • Maldonado RA, von Andrian UH: How tolerogenic dendritic cells induce regulatory T cells. Adv Immunol 2010; 108: 111-165
    • (2010) Adv Immunol , vol.108 , pp. 111-165
    • Maldonado, R.A.1    Von Andrian, U.H.2
  • 31
    • 77955471251 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and myeloid-derived suppressor cells: Potential for regulation and therapy of liver auto- and alloimmunity
    • Natarajan S, Thomson AW: Tolerogenic dendritic cells and myeloid-derived suppressor cells: Potential for regulation and therapy of liver auto- and alloimmunity. Immunobiology 2010; 215: 698-703
    • (2010) Immunobiology , vol.215 , pp. 698-703
    • Natarajan, S.1    Thomson, A.W.2
  • 32
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S: Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9: 162-174
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 33
    • 0345015348 scopus 로고    scopus 로고
    • Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection
    • Peche H, Heslan M, Usal C, Amigorena S, Cuturi MC: Presentation of donor major histocompatibility complex antigens by bone marrow dendritic cell-derived exosomes modulates allograft rejection. Transplantation 2003; 76: 1503-1510
    • (2003) Transplantation , vol.76 , pp. 1503-1510
    • Peche, H.1    Heslan, M.2    Usal, C.3    Amigorena, S.4    Cuturi, M.C.5
  • 35
    • 77949425125 scopus 로고    scopus 로고
    • Generation of tolerogenic dendritic cells via the E-cadherin/beta- cateninsignaling pathway
    • Fu C, Jiang A: Generation of tolerogenic dendritic cells via the E-cadherin/beta-cateninsignaling pathway. Immunol Res 2010; 46: 72- 78
    • (2010) Immunol Res , vol.46 , pp. 72-78
    • Fu, C.1    Jiang, A.2
  • 36
    • 84857466255 scopus 로고    scopus 로고
    • Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs
    • Van den Bossche J, Malissen B, Mantovani A, De Baetselier P, Van Ginderachter JA: Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs. Blood 2012; 119: 1623-1633
    • (2012) Blood , vol.119 , pp. 1623-1633
    • Van Den Bossche, J.1    Malissen, B.2    Mantovani, A.3    De Baetselier, P.4    Van Ginderachter, J.A.5
  • 37
    • 0034672339 scopus 로고    scopus 로고
    • Ligation of E-cadherin on in vitro-generated immature Langerhanstype dendritic cells inhibits their maturation
    • Riedl E, Stockl J, Majdic O, Scheinecker C, Knapp W, Strobl H: Ligation of E-cadherin on in vitro-generated immature Langerhanstype dendritic cells inhibits their maturation. Blood 2000; 96: 4276-4284
    • (2000) Blood , vol.96 , pp. 4276-4284
    • Riedl, E.1    Stockl, J.2    Majdic, O.3    Scheinecker, C.4    Knapp, W.5    Strobl, H.6
  • 38
    • 35348956889 scopus 로고    scopus 로고
    • Dendritic cells break bonds to tolerize
    • van den Broek M: Dendritic cells break bonds to tolerize. Immunity 2007; 27: 544-546
    • (2007) Immunity , vol.27 , pp. 544-546
    • Van Den Broek, M.1
  • 39
    • 77349123232 scopus 로고    scopus 로고
    • Regulation of intestinal homeostasis by dendritic cells
    • Tezuka H, Ohteki T: Regulation of intestinal homeostasis by dendritic cells. Immunol Rev 2010; 234: 247-258
    • (2010) Immunol Rev , vol.234 , pp. 247-258
    • Tezuka, H.1    Ohteki, T.2
  • 40
    • 32944463876 scopus 로고    scopus 로고
    • Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance
    • Dillon S, Agrawal S, Banerjee K, Letterio J, Denning TL, Oswald-Richter K, et al: Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J Clin Invest 2006; 116: 916-928
    • (2006) J Clin Invest , vol.116 , pp. 916-928
    • Dillon, S.1    Agrawal, S.2    Banerjee, K.3    Letterio, J.4    Denning, T.L.5    Oswald-Richter, K.6
  • 41
    • 73349089343 scopus 로고    scopus 로고
    • Apoptotic dendritic cells induce tolerance in mice through suppression of dendritic cell maturation and induction of antigen-specific regulatory T cells
    • Kushwah R, Oliver JR, Zhang J, Siminovitch KA, Hu J: Apoptotic dendritic cells induce tolerance in mice through suppression of dendritic cell maturation and induction of antigen-specific regulatory T cells. J Immunol 2009; 183: 7104-7118
    • (2009) J Immunol , vol.183 , pp. 7104-7118
    • Kushwah, R.1    Oliver, J.R.2    Zhang, J.3    Siminovitch, K.A.4    Hu, J.5
  • 42
    • 80755126873 scopus 로고    scopus 로고
    • Cell death in the maintenance and abrogation of tolerance: The five Ws of dying cells
    • Griffith TS, Ferguson TA: Cell death in the maintenance and abrogation of tolerance: The five Ws of dying cells. Immunity 2011; 35: 456-466
    • (2011) Immunity , vol.35 , pp. 456-466
    • Griffith, T.S.1    Ferguson, T.A.2
  • 43
    • 33748747194 scopus 로고    scopus 로고
    • A vision of cell death: Fas ligand and immune privilege 10 years later
    • Ferguson TA, Griffith TS: A vision of cell death: Fas ligand and immune privilege 10 years later. Immunol Rev 2006; 213: 228-238
    • (2006) Immunol Rev , vol.213 , pp. 228-238
    • Ferguson, T.A.1    Griffith, T.S.2
  • 44
    • 58949097413 scopus 로고    scopus 로고
    • Differential roles of direct and indirect allorecognition pathways in the rejection of skin and corneal transplants
    • Boisgerault F, Liu Y, Anosova N, Dana R, Benichou G: Differential roles of direct and indirect allorecognition pathways in the rejection of skin and corneal transplants. Transplantation 2009; 87: 16-23
    • (2009) Transplantation , vol.87 , pp. 16-23
    • Boisgerault, F.1    Liu, Y.2    Anosova, N.3    Dana, R.4    Benichou, G.5
  • 45
    • 27744482874 scopus 로고    scopus 로고
    • Immunoregulation of dendritic cells
    • Wallet MA, Sen P, Tisch R: Immunoregulation of dendritic cells. Clin Med Res 2005; 3: 166-175
    • (2005) Clin Med Res , vol.3 , pp. 166-175
    • Wallet, M.A.1    Sen, P.2    Tisch, R.3
  • 46
    • 84864757331 scopus 로고    scopus 로고
    • Phosphatidylserine- expressing cell by-products in transfusion: A pro-inflammatory or an anti-inflammatory effect?
    • Saas P, Angelot F, Bardiaux L, Seilles E, Garnache- Ottou F, Perruche S: Phosphatidylserine- expressing cell by-products in transfusion: A pro-inflammatory or an anti-inflammatory effect? Transfus Clin Biol 2012; 19: 90-97
    • (2012) Transfus Clin Biol , vol.19 , pp. 90-97
    • Saas, P.1    Angelot, F.2    Bardiaux, L.3    Seilles, E.4    Garnache- Ottou, F.5    Perruche, S.6
  • 47
    • 2442665179 scopus 로고    scopus 로고
    • Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
    • Hanayama R, Tanaka M, Miyasaka K, Aozasa K, Koike M, Uchiyama Y, et al: Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science 2004; 304: 1147-1150
    • (2004) Science , vol.304 , pp. 1147-1150
    • Hanayama, R.1    Tanaka, M.2    Miyasaka, K.3    Aozasa, K.4    Koike, M.5    Uchiyama, Y.6
  • 48
    • 84871402588 scopus 로고    scopus 로고
    • Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance
    • Kornete M, Piccirillo CA: Functional crosstalk between dendritic cells and Foxp3(+) regulatory T cells in the maintenance of immune tolerance. Front Immunol 2012; 3: 165
    • (2012) Front Immunol , vol.3 , pp. 165
    • Kornete, M.1    Piccirillo, C.A.2
  • 49
    • 34548035850 scopus 로고    scopus 로고
    • Cholera toxin promotes the generation of semimature porcine monocyte-derived dendritic cells that are unable to stimulate T cells
    • Bimczok D, Rau H, Wundrack N, Naumann M, Rothkotter HJ, McCullough K, et al: Cholera toxin promotes the generation of semimature porcine monocyte-derived dendritic cells that are unable to stimulate T cells. Vet Res 2007; 38: 597-612
    • (2007) Vet Res , vol.38 , pp. 597-612
    • Bimczok, D.1    Rau, H.2    Wundrack, N.3    Naumann, M.4    Rothkotter, H.J.5    McCullough, K.6
  • 50
    • 84856731500 scopus 로고    scopus 로고
    • Immune suppression in the tumor microenvironment: A role for dendritic cell-mediated tolerization of T cells
    • Hurwitz AA, Watkins SK: Immune suppression in the tumor microenvironment: A role for dendritic cell-mediated tolerization of T cells. Cancer Immunol Immunother 2012; 61: 289-293
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 289-293
    • Hurwitz, A.A.1    Watkins, S.K.2
  • 51
    • 0000810758 scopus 로고
    • Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice
    • Steinman RM, Witmer MD: Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice. Proc Natl Acad Sci USA 1978; 75: 5132-5136
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 5132-5136
    • Steinman, R.M.1    Witmer, M.D.2
  • 52
    • 80051925503 scopus 로고    scopus 로고
    • Intestinal CD103+ dendritic cells: Master regulators of tolerance?
    • Scott CL, Aumeunier AM, Mowat AM: Intestinal CD103+ dendritic cells: Master regulators of tolerance? Trends Immunol 2011; 32: 412-419
    • (2011) Trends Immunol , vol.32 , pp. 412-419
    • Scott, C.L.1    Aumeunier, A.M.2    Mowat, A.M.3
  • 53
    • 34548208943 scopus 로고    scopus 로고
    • Loss of integrin alpha (v)beta8 on dendritic cells causes autoimmunity and colitis in mice
    • Travis MA, Reizis B, Melton AC, Masteller E, Tang Q, Proctor JM, et al: Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature 2007; 449: 361-365
    • (2007) Nature , vol.449 , pp. 361-365
    • Travis, M.A.1    Reizis, B.2    Melton, A.C.3    Masteller, E.4    Tang, Q.5    Proctor, J.M.6
  • 54
    • 63149172076 scopus 로고    scopus 로고
    • Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells
    • Yamazaki S, Steinman RM: Dendritic cells as controllers of antigen-specific Foxp3+ regulatory T cells. J Dermatol Sci 2009; 54: 69-75
    • (2009) J Dermatol Sci , vol.54 , pp. 69-75
    • Yamazaki, S.1    Steinman, R.M.2
  • 55
    • 51349095960 scopus 로고    scopus 로고
    • Tuning microenvironments: Induction of regulatory T cells by dendritic cells
    • Belkaid Y, Oldenhove G: Tuning microenvironments: Induction of regulatory T cells by dendritic cells. Immunity 2008; 29: 362-371
    • (2008) Immunity , vol.29 , pp. 362-371
    • Belkaid, Y.1    Oldenhove, G.2
  • 56
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, Hall J, Sun CM, Belkaid Y, et al: A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007; 204: 1757-1764
    • (2007) J Exp Med , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6
  • 57
    • 0034176031 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
    • Hwu P, Du MX, Lapointe R, Do M, Taylor MW, Young HA: Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation. J Immunol 2000; 164: 3596-3599
    • (2000) J Immunol , vol.164 , pp. 3596-3599
    • Hwu, P.1    Du, M.X.2    Lapointe, R.3    Do, M.4    Taylor, M.W.5    Young, H.A.6
  • 58
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • Mellor AL, Munn DH: IDO expression by dendritic cells: Tolerance and tryptophan catabolism. Nat Rev Immunol 2004; 4: 762-774
    • (2004) Nat Rev Immunol , vol.4 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 59
    • 84864622877 scopus 로고    scopus 로고
    • A role for tolerogenic dendritic cell-induced B-regulatory cells in type 1 diabetes mellitus
    • Giannoukakis N, Trucco M: A role for tolerogenic dendritic cell-induced B-regulatory cells in type 1 diabetes mellitus. Curr Opin Endocrinol Diabetes Obes 2012; 19: 279-287
    • (2012) Curr Opin Endocrinol Diabetes Obes , vol.19 , pp. 279-287
    • Giannoukakis, N.1    Trucco, M.2
  • 60
    • 84856094049 scopus 로고    scopus 로고
    • Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients
    • Giannoukakis N, Phillips B, Finegold D, Harnaha J, Trucco M: Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care 2011; 34: 2026-2032
    • (2011) Diabetes Care , vol.34 , pp. 2026-2032
    • Giannoukakis, N.1    Phillips, B.2    Finegold, D.3    Harnaha, J.4    Trucco, M.5
  • 61
    • 78149487035 scopus 로고    scopus 로고
    • Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis
    • Harry RA, Anderson AE, Isaacs JD, Hilkens CMU: Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis. Ann Rheum Dis 2010; 69: 2042-2050
    • (2010) Ann Rheum Dis , vol.69 , pp. 2042-2050
    • Harry, R.A.1    Anderson, A.E.2    Isaacs, J.D.3    Hilkens, C.M.U.4
  • 62
    • 2942753928 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor promotes the generation of regulatory DC through induction of IL-10 and IFN-alpha
    • Rutella S, Bonanno G, Pierelli L, Mariotti A, Capoluongo E, Contemi AM, et al: Granulocyte colony-stimulating factor promotes the generation of regulatory DC through induction of IL-10 and IFN-alpha. Eur J Immunol 2004; 34: 1291-1302
    • (2004) Eur J Immunol , vol.34 , pp. 1291-1302
    • Rutella, S.1    Bonanno, G.2    Pierelli, L.3    Mariotti, A.4    Capoluongo, E.5    Contemi, A.M.6
  • 63
    • 77649271584 scopus 로고    scopus 로고
    • Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites
    • Pacciani V, Gregori S, Chini L, Corrente S, Chianca M, Moschese V, et al: Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites. J Allergy Clin Immunol 2010; 125: 727-736
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 727-736
    • Pacciani, V.1    Gregori, S.2    Chini, L.3    Corrente, S.4    Chianca, M.5    Moschese, V.6
  • 65
    • 39749149619 scopus 로고    scopus 로고
    • Vitamin D receptor agonists in the treatment of autoimmune diseases: Selective targeting of myeloid but not plasmacytoid dendritic cells
    • Penna G, Amuchastegui S, Laverny G, Adorini L: Vitamin D receptor agonists in the treatment of autoimmune diseases: Selective targeting of myeloid but not plasmacytoid dendritic cells. J Bone Miner Res 2007; 22(suppl 2): V69-V73
    • (2007) J Bone Miner Res , vol.22 , Issue.SUPPL. 2
    • Penna, G.1    Amuchastegui, S.2    Laverny, G.3    Adorini, L.4
  • 66
    • 0345827684 scopus 로고    scopus 로고
    • Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs
    • Hackstein H, Thomson AW: Dendritic cells: Emerging pharmacological targets of immunosuppressive drugs. Nat Rev Immunol 2004; 4: 24-34
    • (2004) Nat Rev Immunol , vol.4 , pp. 24-34
    • Hackstein, H.1    Thomson, A.W.2
  • 67
    • 34247626840 scopus 로고    scopus 로고
    • Immune modulation and tolerance induction by RelB-silenced dendritic cells through RNA interference
    • Li M, Zhang X, Zheng X, Lian D, Zhang ZX, Ge W, et al: Immune modulation and tolerance induction by RelB-silenced dendritic cells through RNA interference. J Immunol 2007; 178: 5480-5487
    • (2007) J Immunol , vol.178 , pp. 5480-5487
    • Li, M.1    Zhang, X.2    Zheng, X.3    Lian, D.4    Zhang, Z.X.5    Ge, W.6
  • 69
    • 68549109673 scopus 로고    scopus 로고
    • Gene exhibit regulatory DC properties and prolong allograft survival
    • Gene exhibit regulatory DC properties and prolong allograft survival. Cell Mol Immunol 2009; 6: 87-95
    • (2009) Cell Mol Immunol , vol.6 , pp. 87-95
  • 70
    • 84857370127 scopus 로고    scopus 로고
    • Ten Brinke A: IL- 10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction - A comparative study of human clinical- applicable D.C
    • Boks MA, Kager-Groenland JR, Haasjes MS, Zwaginga JJ, van Ham SM, Ten Brinke A: IL- 10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction - a comparative study of human clinical- applicable DC. Clin Immunol 2012; 142: 332-342
    • (2012) Clin Immunol , vol.142 , pp. 332-342
    • Boks, M.A.1    Kager-Groenland, J.R.2    Haasjes, M.S.3    Zwaginga, J.J.4    Van Ham, S.M.5
  • 71
    • 84855472967 scopus 로고    scopus 로고
    • Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
    • Sela U, Olds P, Park A, Schlesinger SJ, Steinman RM: Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice. J Exp Med 2011; 208: 2489-2496
    • (2011) J Exp Med , vol.208 , pp. 2489-2496
    • Sela, U.1    Olds, P.2    Park, A.3    Schlesinger, S.J.4    Steinman, R.M.5
  • 73
    • 34547907690 scopus 로고    scopus 로고
    • Preventing autoimmune arthritis using antigen-specific immature dendritic cells: A novel tolerogenic vaccine
    • Popov I, Li M, Zheng X, San H, Zhang X, Ichim TE, et al: Preventing autoimmune arthritis using antigen-specific immature dendritic cells: A novel tolerogenic vaccine. Arthritis Res Ther 2006; 8:R141
    • (2006) Arthritis Res Ther , vol.8
    • Popov, I.1    Li, M.2    Zheng, X.3    San, H.4    Zhang, X.5    Ichim, T.E.6
  • 74
    • 79251646395 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and their potential applications
    • Hu J, Wan Y: Tolerogenic dendritic cells and their potential applications. Immunology 2011; 132: 307-314
    • (2011) Immunology , vol.132 , pp. 307-314
    • Hu, J.1    Wan, Y.2
  • 75
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J: Taking dendritic cells into medicine. Nature 2007; 449: 419-426
    • (2007) Nature , vol.449 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 77
    • 84857793524 scopus 로고    scopus 로고
    • Decisions about dendritic cells: Past, present, and future
    • Steinman RM: Decisions about dendritic cells: Past, present, and future. Annu Rev Immunol 2012; 30: 1-22
    • (2012) Annu Rev Immunol , vol.30 , pp. 1-22
    • Steinman, R.M.1
  • 79
    • 84874038489 scopus 로고    scopus 로고
    • Therapeutic potential of semi-mature dendritic cells for tolerance induction
    • Lutz MB: Therapeutic potential of semi-mature dendritic cells for tolerance induction. Front Immunol 2012; 3: 123
    • (2012) Front Immunol , vol.3 , pp. 123
    • Lutz, M.B.1
  • 80
    • 79952438687 scopus 로고    scopus 로고
    • Harnessing dendritic cells in inflammatory skin diseases
    • Chu CC, Di Meglio P, Nestle FO: Harnessing dendritic cells in inflammatory skin diseases. Semin Immunol 2011; 23: 28-41
    • (2011) Semin Immunol , vol.23 , pp. 28-41
    • Chu, C.C.1    Di Meglio, P.2    Nestle, F.O.3
  • 81
    • 84886792517 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells in clinical practice
    • Hilkens CMU, Isaacs JD: Tolerogenic dendritic cells in clinical practice. Immunity 2010; 13: 15
    • (2010) Immunity , vol.13 , pp. 15
    • Hilkens, C.M.U.1    Isaacs, J.D.2


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