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Volumn 142, Issue 3, 2012, Pages 332-342

IL-10-generated tolerogenic dendritic cells are optimal for functional regulatory T cell induction - A comparative study of human clinical-applicable DC

Author keywords

CGMP; Migration; Regulatory t cells; Stability; Suppression; Tolerance induction

Indexed keywords

COLECALCIFEROL; DEXAMETHASONE; INTERLEUKIN 10; INTERLEUKIN 1BETA; RAPAMYCIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84857370127     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2011.11.011     Document Type: Article
Times cited : (213)

References (64)
  • 2
    • 76249084928 scopus 로고    scopus 로고
    • Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients
    • Raimondi G., Sumpter T.L., Matta B.M., Pillai M., Corbitt N., Vodovotz Y., Wang Z., Thomson A.W. Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients. J. Immunol. 2010, 184:624-636.
    • (2010) J. Immunol. , vol.184 , pp. 624-636
    • Raimondi, G.1    Sumpter, T.L.2    Matta, B.M.3    Pillai, M.4    Corbitt, N.5    Vodovotz, Y.6    Wang, Z.7    Thomson, A.W.8
  • 3
    • 0037105629 scopus 로고    scopus 로고
    • Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig
    • Bonham C.A., Peng L., Liang X., Chen Z., Wang L., Ma L., Hackstein H., Robbins P.D., Thomson A.W., Fung J.J., Qian S., Lu L. Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig. J. Immunol. 2002, 169:3382-3391.
    • (2002) J. Immunol. , vol.169 , pp. 3382-3391
    • Bonham, C.A.1    Peng, L.2    Liang, X.3    Chen, Z.4    Wang, L.5    Ma, L.6    Hackstein, H.7    Robbins, P.D.8    Thomson, A.W.9    Fung, J.J.10    Qian, S.11    Lu, L.12
  • 6
    • 0037565277 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting autoimmune diabetes
    • Adorini L. Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting autoimmune diabetes. Ann. N. Y. Acad. Sci. 2003, 987:258-261.
    • (2003) Ann. N. Y. Acad. Sci. , vol.987 , pp. 258-261
    • Adorini, L.1
  • 7
    • 49049088794 scopus 로고    scopus 로고
    • Dendritic cell mediated therapy for immunoregulation of type 1 diabetes mellitus
    • Phillips B.E., Giannoukakis N., Trucco M. Dendritic cell mediated therapy for immunoregulation of type 1 diabetes mellitus. Pediatr. Endocrinol. Rev. 2008, 5:873-879.
    • (2008) Pediatr. Endocrinol. Rev. , vol.5 , pp. 873-879
    • Phillips, B.E.1    Giannoukakis, N.2    Trucco, M.3
  • 9
    • 84856094049 scopus 로고    scopus 로고
    • Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients
    • Giannoukakis N., Phillips B., Finegold D., Harnaha J., Trucco M. Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care 2011, 9:2026-2036.
    • (2011) Diabetes Care , vol.9 , pp. 2026-2036
    • Giannoukakis, N.1    Phillips, B.2    Finegold, D.3    Harnaha, J.4    Trucco, M.5
  • 11
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature 1998, 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 12
    • 77954412374 scopus 로고    scopus 로고
    • An optimized CFSE-based T-cell suppression assay to evaluate the suppressive capacity of regulatory T-cells induced by human tolerogenic dendritic cells
    • Boks M.A., Zwaginga J.J., van Ham S.M., B.A.ten An optimized CFSE-based T-cell suppression assay to evaluate the suppressive capacity of regulatory T-cells induced by human tolerogenic dendritic cells. Scand. J. Immunol. 2010, 72:158-168.
    • (2010) Scand. J. Immunol. , vol.72 , pp. 158-168
    • Boks, M.A.1    Zwaginga, J.J.2    van Ham, S.M.3    ten, B.A.4
  • 13
  • 14
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • Sato K., Yamashita N., Baba M., Matsuyama T. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 2003, 101:3581-3589.
    • (2003) Blood , vol.101 , pp. 3581-3589
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 15
    • 0036387002 scopus 로고    scopus 로고
    • IL-10 alters DC function via modulation of cell surface molecules resulting in impaired T-cell responses
    • McBride J.M., Jung T., de Vries J.E., Aversa G. IL-10 alters DC function via modulation of cell surface molecules resulting in impaired T-cell responses. Cell. Immunol. 2002, 215:162-172.
    • (2002) Cell. Immunol. , vol.215 , pp. 162-172
    • McBride, J.M.1    Jung, T.2    de Vries, J.E.3    Aversa, G.4
  • 16
    • 77956538422 scopus 로고    scopus 로고
    • Differentiation of type 1 T regulatory (Tr1) cells by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway
    • Gregori S., Tomasoni D., Pacciani V., Scirpoli M., Battaglia M., Magnani C.F., Hauben E., Roncarolo M.G. Differentiation of type 1 T regulatory (Tr1) cells by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. Blood 2010, 116:935-944.
    • (2010) Blood , vol.116 , pp. 935-944
    • Gregori, S.1    Tomasoni, D.2    Pacciani, V.3    Scirpoli, M.4    Battaglia, M.5    Magnani, C.F.6    Hauben, E.7    Roncarolo, M.G.8
  • 18
    • 22644445634 scopus 로고    scopus 로고
    • Dexamethasone induces IL-10-producing monocyte-derived dendritic cells with durable immaturity
    • Xia C.Q., Peng R., Beato F., Clare-Salzler M.J. Dexamethasone induces IL-10-producing monocyte-derived dendritic cells with durable immaturity. Scand. J. Immunol. 2005, 62:45-54.
    • (2005) Scand. J. Immunol. , vol.62 , pp. 45-54
    • Xia, C.Q.1    Peng, R.2    Beato, F.3    Clare-Salzler, M.J.4
  • 20
    • 70449368149 scopus 로고    scopus 로고
    • Induction of Treg by monocyte-derived DC modulated by vitamin D(3) or dexamethasone: differential role for PD-L1
    • Unger W.W., Laban S., Kleijwegt F.S., van der Slik A.R., Roep B.O. Induction of Treg by monocyte-derived DC modulated by vitamin D(3) or dexamethasone: differential role for PD-L1. Eur. J. Immunol. 2009, 39:3147-3159.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 3147-3159
    • Unger, W.W.1    Laban, S.2    Kleijwegt, F.S.3    van der Slik, A.R.4    Roep, B.O.5
  • 23
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G., Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J. Immunol. 2000, 164:2405-2411.
    • (2000) J. Immunol. , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 26
    • 50449101091 scopus 로고    scopus 로고
    • Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction
    • Fedoric B., Krishnan R. Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction. Immunol. Lett. 2008, 120:49-56.
    • (2008) Immunol. Lett. , vol.120 , pp. 49-56
    • Fedoric, B.1    Krishnan, R.2
  • 28
    • 35548937911 scopus 로고    scopus 로고
    • TGF-[beta] combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors
    • Li G., Abediankenari S., Kim Y.J., Campbell T.B., Ito S., Graham-Evans B., Cooper S., Broxmeyer H.E. TGF-[beta] combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors. Blood 2007, 110:2872-2879.
    • (2007) Blood , vol.110 , pp. 2872-2879
    • Li, G.1    Abediankenari, S.2    Kim, Y.J.3    Campbell, T.B.4    Ito, S.5    Graham-Evans, B.6    Cooper, S.7    Broxmeyer, H.E.8
  • 29
    • 36248980952 scopus 로고    scopus 로고
    • Physiological concentrations of transforming growth factor [beta]1 selectively inhibit human dendritic cell function
    • Fogel-Petrovic M., Long J.A., Misso N.L., Foster P.S., Bhoola K.D., Thompson P.J. Physiological concentrations of transforming growth factor [beta]1 selectively inhibit human dendritic cell function. Int. Immunopharmacol. 2007, 7:1924-1933.
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 1924-1933
    • Fogel-Petrovic, M.1    Long, J.A.2    Misso, N.L.3    Foster, P.S.4    Bhoola, K.D.5    Thompson, P.J.6
  • 30
    • 38349096416 scopus 로고    scopus 로고
    • The presence of GM-CSF and IL-4 interferes with effect of TGF-[beta]1 on antigen presenting cells in patients with multiple sclerosis and in rats with experimental autoimmune encephalomyelitis
    • Xiao B.G., Zhu W.H., Lu C.Z. The presence of GM-CSF and IL-4 interferes with effect of TGF-[beta]1 on antigen presenting cells in patients with multiple sclerosis and in rats with experimental autoimmune encephalomyelitis. Cell. Immunol. 2007, 249:30-36.
    • (2007) Cell. Immunol. , vol.249 , pp. 30-36
    • Xiao, B.G.1    Zhu, W.H.2    Lu, C.Z.3
  • 32
  • 34
    • 0029586520 scopus 로고
    • Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival
    • Rastellini C., Lu L., Ricordi C., Starzl T.E., Rao A.S., Thomson A.W. Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival. Transplantation 1995, 60:1366-1370.
    • (1995) Transplantation , vol.60 , pp. 1366-1370
    • Rastellini, C.1    Lu, L.2    Ricordi, C.3    Starzl, T.E.4    Rao, A.S.5    Thomson, A.W.6
  • 37
    • 56749096845 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells for autoimmune disease and transplantation
    • Thomson A.W., Robbins P.D. Tolerogenic dendritic cells for autoimmune disease and transplantation. Ann. Rheum. Dis. 2008, 67:90-96.
    • (2008) Ann. Rheum. Dis. , vol.67 , pp. 90-96
    • Thomson, A.W.1    Robbins, P.D.2
  • 38
    • 0034919344 scopus 로고    scopus 로고
    • Dendritic cells as a tool to induce anergic and regulatory T cells
    • Jonuleit H., Schmitt E., Steinbrink K., Enk A.H. Dendritic cells as a tool to induce anergic and regulatory T cells. Trends Immunol. 2001, 22:394-400.
    • (2001) Trends Immunol. , vol.22 , pp. 394-400
    • Jonuleit, H.1    Schmitt, E.2    Steinbrink, K.3    Enk, A.H.4
  • 40
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • Roncarolo M.G., Battaglia M. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 2007, 7:585-598.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 585-598
    • Roncarolo, M.G.1    Battaglia, M.2
  • 42
    • 65549136983 scopus 로고    scopus 로고
    • + T regulatory cell-mediated suppression
    • + T regulatory cell-mediated suppression. Immunity 2009, 30:636-645.
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 43
    • 33747607995 scopus 로고    scopus 로고
    • Generation of dendritic cells for immunotherapy is minimally impaired by granulocytes in the monocyte preparation
    • ten Brinke A., Karsten M.L., Dieker M.C., Zwaginga J.J., Vrielink H., Marieke van Ham S. Generation of dendritic cells for immunotherapy is minimally impaired by granulocytes in the monocyte preparation. Immunobiology 2006, 211:633-640.
    • (2006) Immunobiology , vol.211 , pp. 633-640
    • ten Brinke, A.1    Karsten, M.L.2    Dieker, M.C.3    Zwaginga, J.J.4    Vrielink, H.5    Marieke van Ham, S.6
  • 44
    • 34648817211 scopus 로고    scopus 로고
    • The clinical grade maturation cocktail monophosphoryl lipid A plus IFN[gamma] generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization
    • ten Brinke A., Karsten M.L., Dieker M.C., Zwaginga J.J., van Ham S.M. The clinical grade maturation cocktail monophosphoryl lipid A plus IFN[gamma] generates monocyte-derived dendritic cells with the capacity to migrate and induce Th1 polarization. Vaccine 2007, 25:7145-7152.
    • (2007) Vaccine , vol.25 , pp. 7145-7152
    • ten Brinke, A.1    Karsten, M.L.2    Dieker, M.C.3    Zwaginga, J.J.4    van Ham, S.M.5
  • 46
    • 0029201182 scopus 로고
    • Monophosphoryl lipid A as an adjuvant. Past experiences and new directions
    • Ulrich J.T., Myers K.R. Monophosphoryl lipid A as an adjuvant. Past experiences and new directions. Pharm. Biotechnol. 1995, 6:495-524.
    • (1995) Pharm. Biotechnol. , vol.6 , pp. 495-524
    • Ulrich, J.T.1    Myers, K.R.2
  • 48
    • 68749114977 scopus 로고    scopus 로고
    • Role of immunolglobulin-like transcript family receptors and their ligands in suppressor T-cell-induced dendritic cell tolerization
    • Chui C.S., Li D. Role of immunolglobulin-like transcript family receptors and their ligands in suppressor T-cell-induced dendritic cell tolerization. Hum. Immunol. 2009, 70:686-691.
    • (2009) Hum. Immunol. , vol.70 , pp. 686-691
    • Chui, C.S.1    Li, D.2
  • 52
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit H., Kuhn U., Muller G., Steinbrink K., Paragnik L., Schmitt E., Knop J., Enk A.H. Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur. J. Immunol. 1997, 27:3135-3142.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6    Knop, J.7    Enk, A.H.8
  • 54
    • 34547152610 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and the quest for transplant tolerance
    • Morelli A.E., Thomson A.W. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat. Rev. Immunol. 2007, 7:610-621.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 610-621
    • Morelli, A.E.1    Thomson, A.W.2
  • 55
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • Kalinski P., Vieira P.L., Schuitemaker J.H.N., de Jong E.C., Kapsenberg M.L. Prostaglandin E2 is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood 2001, 97:3466-3469.
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.N.3    de Jong, E.C.4    Kapsenberg, M.L.5
  • 58
    • 33747362224 scopus 로고    scopus 로고
    • Dendritic cells matured with TNF can be further activated in vitro and after subcutaneous injection in vivo which converts their tolerogenicity into immunogenicity
    • Voigtlander C., Rossner S., Cierpka E., Theiner G., Wiethe C., Menges M., Schuler G., Lutz M.B. Dendritic cells matured with TNF can be further activated in vitro and after subcutaneous injection in vivo which converts their tolerogenicity into immunogenicity. J. Immunother. 2006, 29:407-415.
    • (2006) J. Immunother. , vol.29 , pp. 407-415
    • Voigtlander, C.1    Rossner, S.2    Cierpka, E.3    Theiner, G.4    Wiethe, C.5    Menges, M.6    Schuler, G.7    Lutz, M.B.8
  • 60
    • 0035862333 scopus 로고    scopus 로고
    • Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
    • Dhodapkar M.V., Steinman R.M., Krasovsky J., Munz C., Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J. Exp. Med. 2001, 193:233-238.
    • (2001) J. Exp. Med. , vol.193 , pp. 233-238
    • Dhodapkar, M.V.1    Steinman, R.M.2    Krasovsky, J.3    Munz, C.4    Bhardwaj, N.5
  • 61
    • 0036530016 scopus 로고    scopus 로고
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
    • + anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 2002, 99:2468-2476.
    • (2002) Blood , vol.99 , pp. 2468-2476
    • Steinbrink, K.1    Graulich, E.2    Kubsch, S.3    Knop, J.4    Enk, A.H.5
  • 63
    • 13144256708 scopus 로고    scopus 로고
    • Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival
    • Taner T., Hackstein H., Wang Z., Morelli A.E., Thomson A.W. Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival. Am. J. Transplant. 2005, 5:228-236.
    • (2005) Am. J. Transplant. , vol.5 , pp. 228-236
    • Taner, T.1    Hackstein, H.2    Wang, Z.3    Morelli, A.E.4    Thomson, A.W.5
  • 64
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • Hackstein H., Taner T., Zahorchak A.F., Morelli A.E., Logar A.J., Gessner A., Thomson A.W. Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 2003, 101:4457-4463.
    • (2003) Blood , vol.101 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3    Morelli, A.E.4    Logar, A.J.5    Gessner, A.6    Thomson, A.W.7


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