Exploring the multifactorial nature of autism through computational systems biology: Calcium and the Rho GTPase RAC1 under the spotlight

NeuroMolecular Medicine

Volumn 15, Issue 2, 2013, Pages 364-383

  Zeidán Chuliá, Fares ^a   Rybarczyk Filho, José Luiz ^a,b   Salmina, Alla B ^c   De Oliveira, Ben Hur Neves ^a   Noda, Mami ^d   Moreira, José Cláudio F ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c KRASNOYARSK STATE MEDICAL UNIVERSITY   (Russian Federation)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Autism spectrum disorders; Gene expression; In silico model; Polymorphism; Xenobiotic

Indexed keywords

CALCIUM; PROTEIN CDC42; RAC PROTEIN; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN FILAMENT; AUTISM; CALCIUM SIGNALING; CEREBELLUM; ENVIRONMENTAL STRESS; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MACROGLIA; MICROARRAY ANALYSIS; NERVE CELL PLASTICITY; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW; SYSTEMS BIOLOGY;

AUTISTIC DISORDER; BIOPSY; CALCIUM; CELL COMMUNICATION; CENTRAL NERVOUS SYSTEM; CEREBELLUM; DATABASES, FACTUAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; GENE-ENVIRONMENT INTERACTION; HUMANS; MICROARRAY ANALYSIS; MODELS, GENETIC; MODELS, NEUROLOGICAL; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; NEUROTRANSMITTER AGENTS; RAC1 GTP-BINDING PROTEIN; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; SYSTEMS BIOLOGY;

EID: 84877771585     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-013-8224-3     Document Type: Review

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