Role of L- and N-type calcium channels in the pathophysiology of traumatic spinal cord white matter injury

Neuroscience

Volumn 99, Issue 1, 2000, Pages 179-188

  Agrawal, S K ^a   Nashmi, R ^a   Fehlings, M G ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Astrocytes; Calcium channels; Conotoxin; Glia; Oligodendrocytes; Rat

Indexed keywords

CADMIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; COBALT; DILTIAZEM; GLIAL FIBRILLARY ACIDIC PROTEIN; OMEGA CONOTOXIN GVIA; VERAPAMIL;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CALCIUM CURRENT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; WHITE MATTER;

ANIMALS; AXONS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CALCIUM CHANNELS, N-TYPE; MALE; NEUROGLIA; RATS; RATS, WISTAR; SPINAL CORD; SPINAL CORD INJURIES;

EID: 0034718228     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00165-2     Document Type: Article

References (58)

1. 2+ exchanger. J. Neurosci. 16:1996;545-552.
2. Agrawal S.K., Fehlings M.G. Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury. J. Neurosci. 17:1997;1055-1063.
3. Agrawal S.K., Theriault E., Fehlings M.G. Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury. J. Neurotrauma. 15:1998;929-941.
4. 2+ channels present in synaptosomes from rat and chicken central nervous system. J. Neurochem. 64:1995;2544-2551.
5. Balentine J.D., Spector M. Calcification of axons in experimental spinal cord trauma. Ann. Neurol. 2:1977;520-523.
6. Barres B.A., Chun L.L., Corey D.P. Calcium current in cortical astrocytes: induction by cAMP and neurotransmitters and permissive effect of serum factors. J. Neurosci. 9:1989;3169-3175.
7. Barres B.A., Chun L.L., Corey D.P. Ion channel expression by white matter glia: I. Type 2 astrocytes and oligodendrocytes. Glia. 1:1988;10-30.
8. Barres B.A., Koroshetz W.J., Chun L.L., Corey D.P. Ion channel expression by white matter glia: the type-1 astrocyte. Neuron. 5:1990;527-544.
9. Barres B.A., Koroshetz W.J., Swartz K.J., Chun L.L., Corey D.P. Ion channel expression by white matter glia: the O-2A glial progenitor cell. Neuron. 4:1990;507-524.
10. Bengtsson F. and Siesjo B. K. (1990) Cell damage in cerebral ischemia: physiological, biochemical and structural aspects. In Cerebral Ischemia and Resuscitation (eds Schurr A. and Rigor B. M.), pp. 215-233. CRC, Boca Raton, FL.
11. Berger T., Schnitzer J., Orkand P.M., Kettenmann H. Sodium and calcium currents in glial cells of the mouse corpus callosum slice. Eur. J. Neurosci. 4:1992;1271-1284.
12. Borges K., Wolswijk G., Ohlemeyer C., Kettenmann H. Adult rat optic nerve oligodendrocyte progenitor cells express a distinct repertoire of voltage- and ligand-gated ion channels. J. Neurosci. Res. 40:1995;591-605.
13. 2+ channel antagonists. Trends pharmac. Sci. 13:1992;256-262.
14. Chiu S.Y., Kriegler S. Neurotransmitter-mediated signaling between axons and glial cells. Glia. 11:1994;191-200.
15. Choi D.W. Ischemia-induced neuronal apoptosis. Curr. Opin. Neurobiol. 6:1996;667-672.
16. Fehlings M.G., Nashmi R. A new model of acute compressive spinal cord injury in vitro. J. Neurosci. Meth. 71:1997;215-224.
17. Fehlings M.G., Tator C.H., Linden R.D. The effect of nimodipine and dextran on axonal function and blood flow following experimental spinal cord injury. J. Neurosurg. 71:1989;403-416.
18. Fern R. Intracellular calcium and cell death during ischemia in neonatal rat white matter astrocytes in situ. J. Neurosci. 18:1998;7232-7243.
19. Fern R., Ransom B.R., Waxman S.G. Voltage-gated calcium channels in CNS white matter: role in anoxic injury. J. Neurophysiol. 74:1995;369-377.
20. Gean P.W., Chou S.M. Suppression of 4-aminopyridine-induced paroxysmal depolarizing shift in rat amygdaloid neurons by diltiazem. Brain Res. 560:1991;306-310.
21. 2+-accumulation in experimental spinal cord trauma. Brain Res. 211:1981;476-479.
22. Hille B. Ionic Channels of Excitable Membranes. 2nd :1992;Sinauer, Sunderland, MA.
23. 2+ channel diversity. A. Rev. Neurosci. 17:1994;399-418.
24. Huguenard J.R. Low-threshold calcium currents in central nervous system neurons. A. Rev. Physiol. 58:1996;329-348.
25. Huh K.H., Wenthold R.J. Turnover analysis of glutamate receptors identifies a rapidly degraded pool of the N-methyl-D-aspartate receptor subunit, NR1, in cultured cerebellar granule cells. J. biol. Chem. 274:1999;151-157.
26. 2+ channels in anoxic injury of spinal cord white matter. Brain Res. 817:1999;84-92.
27. Kriegler S., Chiu S.Y. Calcium signaling of glial cells along mammalian axons. J. Neurosci. 13:1993;4229-4245.
28. Lacinova L., Welling A., Bosse E., Ruth P., Flockerzi V., Hofmann F. Interaction of Ro 40-5967 and verapamil with the stably expressed alpha 1-subunit of the cardiac L-type calcium channel. J. Pharmac. exp. Ther. 274:1995;54-63.
29. + channel gene transcription and protein expression in pituitary cells. J. biol. Chem. 270:1995;6036-6041.
30. Lev-Ram V., Ellisman M.H. Axonal activation-induced calcium transients in myelinating Schwann cells, sources, and mechanisms. J. Neurosci. 15:1995;2628-2637.
31. Lev-Ram V., Grinvald A. Activity-dependent calcium transients in central nervous system myelinated axons revealed by the calcium indicator Fura-2. Biophys. J. 52:1987;571-576.
32. +-dependent communication between central nervous system myelinated axons and oligodendrocytes revealed by voltage-sensitive dyes. Proc. natn. Acad. Sci. USA. 83:1986;6651-6655.
33. +-dependent glutamate transport. J. Neurosci. 19:1999;RC16.
34. Li S., Stys P.K. Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter. J. Neurosci. 20:2000;1190-1198.
35. 2+ channel in chicken brain synaptosomes. Brain Res. 643:1994;204-210.
36. Luscher C., Xia H., Beattie E.C., Carroll R.C., von Zastrow M., Malenka R.C., Nicoll R.A. Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron. 24:1999;649-658.
37. MacVicar B.A. Voltage-dependent calcium channels in glial cells. Science. 226:1984;1345-1347.
38. Marrero H., Orkand R.K. Nerve impulses increase glial intercellular permeability. Glia. 16:1996;285-289.
39. Ojcius D.M., Zychlinsky A., Zheng L.M., Young J.D. Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. Expl Cell Res. 197:1991;43-49.
40. Philippi M., Vyklicky L., Orkand R.K. Potassium currents in cultured glia of the frog optic nerve. Glia. 17:1996;72-82.
41. Regan R.F., Choi D.W. Glutamate neurotoxicity in spinal cord cell culture. Neuroscience. 43:1991;585-591.
42. Sato K., Park N.G., Kohno T., Maeda T., Kim J.I., Kato R., Takahashi M. Role of basic residues for the binding of omega-conotoxin GVIA to N-type calcium channels. Biochem. biophys. Res. Commun. 194:1993;1292-1296.
43. Schumacher A., Eubanks J., Fehlings M.G. Increased calpain-1 mediated proteolysis and preferential degradation of dephosphorylated NF200 following traumatic spinal cord injury. Neuroscience. 91:1999;733-744.
44. Siesjo B.K., Katsura K., Kristian T. Acidosis-related damage. Adv. Neurol. 71:1996;209-233.
45. Siman R., Noszek J.C. Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo. Neuron. 1:1988;279-287.
46. 2+ channel current by diltiazem in human mesenteric arterial myocytes. Eur. J. Pharmac. 360:1998;81-90.
47. Stys P.K. Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics. J. cerebr. Blood Flow Metab. 18:1998;2-25.
48. Stys P.K., Ransom B.R., Waxman S.G. Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia. Neurosci. Lett. 115:1990;293-299.
49. 2+ exchanger. J. Neurosci. 12:1992;430-439.
50. Sun B.B., Chiu S.Y. N-Type calcium channels and their regulation by GABAB receptors in axons of neonatal rat optic nerve. J. Neurosci. 19:1999;5185-5194.
51. Tator C.H., Fehlings M.G. Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J. Neurosurg. 75:1991;15-26.
52. Theriault E., Fehlings M.G., Agrawal S.K., Mills L. Intracellular calcium regulation in astrocytes in an adult rat spinal cord preparation. Soc. Neurosci. Abstr. 20:1994;1071.
53. Tymianski M., Tator C.H. Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury. Neurosurgery. 38:1996;1176-1195.
54. Verkhratsky A.N., Trotter J., Kettenmann H. Cultured glial precursor cells from mouse cortex express two types of calcium currents. Neurosci. Lett. 112:1990;194-198.
55. 2+ channel expression in the oligodendrocyte lineage. Eur. J. Neurosci. 4:1992;1035-1048.
56. Wan Q., Xiong Z.G., Man H.Y., Ackerley C.A., Braunton J., Lu W.Y., Becker L.E., MacDonald J.F., Wang Y.T. Recruitment of functional GABA(A) receptors to postsynaptic domains by insulin. Nature. 388:1997;686-690.
57. Waxman S.G., Ritchie J.M. Molecular dissection of the myelinated axon. Ann. Neurol. 33:1993;121-136.
58. Werth J.L., Thayer S.A. Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons. J. Neurosci. 14:1994;348-356.