Small interfering RNA targeting T-cell Ig mucin-3 decreases allergic airway inflammation and hyperresponsiveness

Inflammation

Volumn 36, Issue 3, 2013, Pages 582-591

  Lu, Xiao Xia ^a   McCoy, Karen S ^b   Xu, Jia Li ^a   Hu, Wei Kun ^c   Chen, He Bin ^a  

^a Wuhan Women and Children Health Care Center ^*  (China)

^b OHIO STATE UNIVERSITY   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

asthma; CD4+ T cell; siRNA; Tim 3

Indexed keywords

BINDING PROTEIN; SHORT HAIRPIN RNA; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING MOLECULE 3; UNCLASSIFIED DRUG;

ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TARGETING; FEMALE; GENE SILENCING; IN VIVO STUDY; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT ALLERGY; RNA INTERFERENCE; TH1 CELL; TH17 CELL;

ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; CELLS, CULTURED; FEMALE; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; OVALBUMIN; RECEPTORS, VIRUS; RESPIRATORY HYPERSENSITIVITY; RNA INTERFERENCE; RNA, SMALL INTERFERING; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS;

EID: 84877742952     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-012-9580-0     Document Type: Article

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