-
1
-
-
0020563638
-
Patterned distribution of metastases from malignant melanoma in humans
-
6850649
-
de la Monte S, Moore G, Hutchins G. Patterned distribution of metastases from malignant melanoma in humans. Cancer Res. 1983;43:3427-33.
-
(1983)
Cancer Res
, vol.43
, pp. 3427-3433
-
-
De La Monte, S.1
Moore, G.2
Hutchins, G.3
-
2
-
-
0031975369
-
Demographics, prognosis and therapy in 702 patients with brain metastases from malignant melanoma
-
9420067 10.3171/jns.1998.88.1.0011 1:STN:280:DyaK1c%2FotVagtg%3D%3D
-
Sampson J, Carter J, Friedman A, et al. Demographics, prognosis and therapy in 702 patients with brain metastases from malignant melanoma. J Neurosurg. 1998;88:11-20.
-
(1998)
J Neurosurg
, vol.88
, pp. 11-20
-
-
Sampson, J.1
Carter, J.2
Friedman, A.3
-
3
-
-
0036405461
-
Management of brain metastases
-
12382150 10.1007/s00415-002-0870-6
-
Soffietti R, Ruda R, Mutani R. Management of brain metastases. J Neurol. 2002;249:1357-69.
-
(2002)
J Neurol
, vol.249
, pp. 1357-1369
-
-
Soffietti, R.1
Ruda, R.2
Mutani, R.3
-
4
-
-
2142644507
-
Determinants of outcome in melanoma patients with cerebral metastases
-
15051777 10.1200/JCO.2004.08.140 1:STN:280:DC%2BD2c7lslOktA%3D%3D
-
Fife KM, Colman MH, Stevens GN, et al. Determinants of outcome in melanoma patients with cerebral metastases. J Clin Oncol. 2004;22:1293-300.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1293-1300
-
-
Fife, K.M.1
Colman, M.H.2
Stevens, G.N.3
-
5
-
-
0037089581
-
Survival by radiation therapy oncology group recursive partitioning analysis class and treatment modality in patients with brain metastases from malignant melanoma: A retrospective study
-
12001126 10.1002/cncr.10426
-
Buchsbaum JC, Suh JH, Lee SY, et al. Survival by radiation therapy oncology group recursive partitioning analysis class and treatment modality in patients with brain metastases from malignant melanoma: a retrospective study. Cancer. 2002;94:2265-72.
-
(2002)
Cancer
, vol.94
, pp. 2265-2272
-
-
Buchsbaum, J.C.1
Suh, J.H.2
Lee, S.Y.3
-
6
-
-
0037302053
-
Surgical treatment of malignant melanoma
-
12691453 10.1016/S0039-6109(02)00205-0
-
Essner R. Surgical treatment of malignant melanoma. Surg Clin North Am. 2003;83:109-56.
-
(2003)
Surg Clin North Am
, vol.83
, pp. 109-156
-
-
Essner, R.1
-
7
-
-
80955130103
-
Safety and clinical activity of ipilimumab in melanoma patients with brain metastases: Retrospective analysis of data from a Phase II trial
-
22051508 10.1097/CMR.0b013e32834d3d88 1:CAS:528:DC%2BC3MXhsVamu73F This paper is an important retrospective review of [42] focusing on the outcomes of 12 patients with prior, but not active, brain metastases. The data from this study showed efficacy in the patient population with brain metastases
-
Weber JS, Amin A, Minor D, et al. Safety and clinical activity of ipilimumab in melanoma patients with brain metastases: retrospective analysis of data from a Phase II trial. Melanoma Res. 2011;21:530-4. This paper is an important retrospective review of [42] focusing on the outcomes of 12 patients with prior, but not active, brain metastases. The data from this study showed efficacy in the patient population with brain metastases.
-
(2011)
Melanoma Res
, vol.21
, pp. 530-534
-
-
Weber, J.S.1
Amin, A.2
Minor, D.3
-
8
-
-
79952264449
-
Outcome predictors of Gamma Knife surgery for melanoma brain metastases
-
20524829 10.3171/2010.5.JNS1014 This paper reviewed 333 patients with melanoma with brain lesions to determine prognostic factors for patients undergoing stereotactic radiosurgery. The large cohort with this specific diagnosis makes this a valuable publication
-
Liew DN, Kano H, Kondziolka D, et al. Outcome predictors of Gamma Knife surgery for melanoma brain metastases. J Neurosurg. 2011;114:769-79. This paper reviewed 333 patients with melanoma with brain lesions to determine prognostic factors for patients undergoing stereotactic radiosurgery. The large cohort with this specific diagnosis makes this a valuable publication.
-
(2011)
J Neurosurg
, vol.114
, pp. 769-779
-
-
Liew, D.N.1
Kano, H.2
Kondziolka, D.3
-
9
-
-
44849122610
-
Brain and leptomeningeal metastases from cutaneous melanoma: Survival outcomes based on clinical features
-
18287337 10.1215/15228517-2007-058
-
Raizer JJ, Hwu WJ, Panageas KS, et al. Brain and leptomeningeal metastases from cutaneous melanoma: survival outcomes based on clinical features. Neuro Oncol. 2008;10:199-207.
-
(2008)
Neuro Oncol
, vol.10
, pp. 199-207
-
-
Raizer, J.J.1
Hwu, W.J.2
Panageas, K.S.3
-
10
-
-
34250177984
-
The Blood-Brain barrier and cancer: Transporters, treatment, and Trojan horses
-
17363519 10.1158/1078-0432.CCR-06-2854 1:CAS:528:DC%2BD2sXivV2gtrg%3D
-
Deeken JF, Loscher W. The Blood-Brain barrier and cancer: transporters, treatment, and Trojan horses. Clin Cancer Res. 2007;13:1663-74.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1663-1674
-
-
Deeken, J.F.1
Loscher, W.2
-
11
-
-
67650529123
-
Diagnosis and treatment of melanoma brain metastasis: A literature review
-
19556965
-
Sloan AE, Nock CJ, Einstein DB. Diagnosis and treatment of melanoma brain metastasis: a literature review. Cancer Control. 2009;16:248-55.
-
(2009)
Cancer Control
, vol.16
, pp. 248-255
-
-
Sloan, A.E.1
Nock, C.J.2
Einstein, D.B.3
-
12
-
-
48949117580
-
The blood-central nervous system barriers actively control immune cell entry into the central nervous system
-
18673197 10.2174/138161208784705432 1:CAS:528:DC%2BD1cXoslylu7c%3D
-
Engelhardt B. The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr Pharm Des. 2008;14:1555-65.
-
(2008)
Curr Pharm des
, vol.14
, pp. 1555-1565
-
-
Engelhardt, B.1
-
13
-
-
0037942601
-
The blood-brain barrier and its role in immune privilege in the central nervous system
-
12834104 1:CAS:528:DC%2BD3sXlt1yqurk%3D
-
Pachter JS, de Vries HE, Fabry Z. The blood-brain barrier and its role in immune privilege in the central nervous system. J Neuropathol Exp Neurol. 2003;62:593-604.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 593-604
-
-
Pachter, J.S.1
De Vries, H.E.2
Fabry, Z.3
-
14
-
-
0022576609
-
Monoclonal antibody analysis of MHC expression in human brain biopsies: Tissue ranging from 'histologically normal' to that showing different levels of glial tumor involvement
-
2422272 1:STN:280:DyaL287pslOkug%3D%3D
-
Lampson LA, Hickey WF. Monoclonal antibody analysis of MHC expression in human brain biopsies: tissue ranging from 'histologically normal' to that showing different levels of glial tumor involvement. J Immunol. 1986;136:4054-62.
-
(1986)
J Immunol
, vol.136
, pp. 4054-4062
-
-
Lampson, L.A.1
Hickey, W.F.2
-
15
-
-
72449154567
-
The role of microglia in central nervous system immunity and glioma immunology
-
19926287 10.1016/j.jocn.2009.05.006
-
Yang I, Han SJ, Kaur G, Crane C, Parsa AT. The role of microglia in central nervous system immunity and glioma immunology. J Clin Neurosci. 2010;17:6-10.
-
(2010)
J Clin Neurosci
, vol.17
, pp. 6-10
-
-
Yang, I.1
Han, S.J.2
Kaur, G.3
Crane, C.4
Parsa, A.T.5
-
16
-
-
63549090599
-
Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system
-
19264338 10.1016/j.virol.2009.01.032 1:CAS:528:DC%2BD1MXktF2qu7g%3D
-
Steel CD, Hahto SM, Ciavarra RP. Peripheral dendritic cells are essential for both the innate and adaptive antiviral immune responses in the central nervous system. Virology. 2009;387:117-26.
-
(2009)
Virology
, vol.387
, pp. 117-126
-
-
Steel, C.D.1
Hahto, S.M.2
Ciavarra, R.P.3
-
17
-
-
80051762728
-
Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle
-
21349152 10.1186/2045-8118-8-4
-
Engelhardt B, Coisne C. Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle. Fluids Barriers CNS. 2011;8:4.
-
(2011)
Fluids Barriers CNS
, vol.8
, pp. 4
-
-
Engelhardt, B.1
Coisne, C.2
-
18
-
-
79958045766
-
The biology of brain metastases - Translation to new therapies
-
21487419 1:CAS:528:DC%2BC3MXmvFOgtr8%3D
-
Eichler AF, Chung E, Kodack DP, et al. The biology of brain metastases - translation to new therapies. Nat Rev Clin Oncol. 2011;8:344-56.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 344-356
-
-
Eichler, A.F.1
Chung, E.2
Kodack, D.P.3
-
20
-
-
0036970548
-
Docetaxel in combination with dacarbazine in patients with advanced melanoma
-
12417787 10.1159/000066225 1:CAS:528:DC%2BD38XosVKntr8%3D
-
Bafaloukos D, Aravantinos G, Fountzilas G, et al. Docetaxel in combination with dacarbazine in patients with advanced melanoma. Oncology. 2002;63:333-7.
-
(2002)
Oncology
, vol.63
, pp. 333-337
-
-
Bafaloukos, D.1
Aravantinos, G.2
Fountzilas, G.3
-
21
-
-
1842562211
-
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: A phase III study
-
15020614 10.1200/JCO.2004.04.165 1:CAS:528:DC%2BD2cXptlCku7Y%3D
-
Avril MF, Aamdal S, Grob JJ, et al. Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study. J Clin Oncol. 2004;22:1118-25.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1118-1125
-
-
Avril, M.F.1
Aamdal, S.2
Grob, J.J.3
-
22
-
-
2942689983
-
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: A phase II study
-
15169796 10.1200/JCO.2004.11.044 1:CAS:528:DC%2BD2cXpsVWlsLg%3D
-
Agarwala SS, Kirkwood JM, Gore M, et al. Temozolomide for the treatment of brain metastases associated with metastatic melanoma: a phase II study. J Clin Oncol. 2004;22:2101-7.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2101-2107
-
-
Agarwala, S.S.1
Kirkwood, J.M.2
Gore, M.3
-
23
-
-
0033989205
-
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
-
10623706 1:CAS:528:DC%2BD3cXmtFSqsQ%3D%3D
-
Middleton MR, Grob JJ, Aaronson N, et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol. 2000;18:158-66.
-
(2000)
J Clin Oncol
, vol.18
, pp. 158-166
-
-
Middleton, M.R.1
Grob, J.J.2
Aaronson, N.3
-
24
-
-
79958783120
-
Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: Final results of a randomised phase III study (EORTC 18032)
-
EORTC Melanoma Group et al. 21600759 10.1016/j.ejca.2011.04.030 1:CAS:528:DC%2BC3MXnsleju7w%3D
-
Patel PM, Suciu S, Mortier L, EORTC Melanoma Group, et al. Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032). Eur J Cancer. 2011;47:1476-83.
-
(2011)
Eur J Cancer
, vol.47
, pp. 1476-1483
-
-
Patel, P.M.1
Suciu, S.2
Mortier, L.3
-
25
-
-
84877726977
-
-
Micromedex 2.0 Available at Accessed on November 20, 2012
-
Micromedex 2.0 Available at http://www.thomsonhc.com/micromedex2/ librarian Accessed on November 20, 2012.
-
-
-
-
26
-
-
0034833541
-
Temozolomide for treating brain metastases
-
11550137 10.1016/S0093-7754(01)90069-7 1:CAS:528:DC%2BD3MXntFGht7o%3D
-
Abrey LE, Christodoulou C. Temozolomide for treating brain metastases. Semin Oncol. 2001;28:34-42.
-
(2001)
Semin Oncol
, vol.28
, pp. 34-42
-
-
Abrey, L.E.1
Christodoulou, C.2
-
27
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
15758009 10.1056/NEJMoa043330 1:CAS:528:DC%2BD2MXit1Wksbk%3D
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
28
-
-
0036246203
-
Effect of temozolomide on central nervous system relapse in patients with advanced melanoma
-
11930115 10.1097/00008390-200204000-00011 1:CAS:528:DC%2BD38XjslCqsrw%3D
-
Paul MJ, Summers Y, Calvert AH, Rustin G, et al. Effect of temozolomide on central nervous system relapse in patients with advanced melanoma. Melanoma Res. 2002;12:175-8.
-
(2002)
Melanoma Res
, vol.12
, pp. 175-178
-
-
Paul, M.J.1
Summers, Y.2
Calvert, A.H.3
Rustin, G.4
-
29
-
-
79958177869
-
Italian Melanoma Intergroup Central nervous system failure in melanoma patients: Results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens
-
21610711 10.1038/bjc.2011.178 1:CAS:528:DC%2BC3MXntV2hsLk%3D This prospective trial looked out the outcome of CNS progression in patients with metastatic melanoma treated with standard systemic therapies temozolomide and dacarbazine and found no difference in progression to the brain
-
Chiarion-Sileni V, Guida M, Ridolfi L, et al. Italian Melanoma Intergroup Central nervous system failure in melanoma patients: results of a randomised, multicentre phase 3 study of temozolomide- and dacarbazine- based regimens. Br J Cancer. 2011;104:1816-21. This prospective trial looked out the outcome of CNS progression in patients with metastatic melanoma treated with standard systemic therapies temozolomide and dacarbazine and found no difference in progression to the brain.
-
(2011)
Br J Cancer
, vol.104
, pp. 1816-1821
-
-
Chiarion-Sileni, V.1
Guida, M.2
Ridolfi, L.3
-
30
-
-
77949638554
-
Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: A multicenter phase II study
-
19767314 10.1093/annonc/mdp343 1:STN:280:DC%2BC3c7isVGmsA%3D%3D
-
Siena S, Crinò L, Danova M, et al. Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. Ann Oncol. 2010;21:655-61.
-
(2010)
Ann Oncol
, vol.21
, pp. 655-661
-
-
Siena, S.1
Crinò, L.2
Danova, M.3
-
31
-
-
84855161455
-
Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide
-
22199328 1:CAS:528:DC%2BC38XhsFCltLk%3D
-
Devito N, Yu M, Chen R, Pan E. Retrospective study of patients with brain metastases from melanoma receiving concurrent whole-brain radiation and temozolomide. Anticancer Res. 2011;31:4537-43.
-
(2011)
Anticancer Res
, vol.31
, pp. 4537-4543
-
-
Devito, N.1
Yu, M.2
Chen, R.3
Pan, E.4
-
32
-
-
0036208833
-
Temozolomide and whole brain irradiation in melanoma metastatic to the brain: A phase II trial of the Cytokine Working Group
-
11935312 10.1007/s00432-002-0323-8 1:CAS:528:DC%2BD38XksFGnurg%3D
-
Margolin K, Atkins B, Thompson A, et al. Temozolomide and whole brain irradiation in melanoma metastatic to the brain: a phase II trial of the Cytokine Working Group. J Cancer Res Clin Oncol. 2002;128:214-8.
-
(2002)
J Cancer Res Clin Oncol
, vol.128
, pp. 214-218
-
-
Margolin, K.1
Atkins, B.2
Thompson, A.3
-
33
-
-
78649998499
-
Brain metastases from melanoma: Is there a role for concurrent temozolomide in addition to whole-brain radiation therapy?
-
20042969 10.1097/COC.0b013e3181c4c54b 1:CAS:528:DC%2BC3cXhsFSlt7bK
-
Schild SE, Behl D, Markovic SN, et al. Brain metastases from melanoma: Is there a role for concurrent temozolomide in addition to whole-brain radiation therapy? Am J Clin Oncol. 2010;33:633-6.
-
(2010)
Am J Clin Oncol
, vol.33
, pp. 633-636
-
-
Schild, S.E.1
Behl, D.2
Markovic, S.N.3
-
34
-
-
84887618276
-
Combining stereotactic radiosurgery and systemic therapy for brain metastases: A potential role for temozolomide
-
22908046 10.3389/fonc.2012.00099 1:CAS:528:DC%2BC3sXmvFarsL8%3D
-
Hardee ME, Formenti SC. Combining stereotactic radiosurgery and systemic therapy for brain metastases: a potential role for temozolomide. Front Oncol. 2012;2:99.
-
(2012)
Front Oncol
, vol.2
, pp. 99
-
-
Hardee, M.E.1
Formenti, S.C.2
-
35
-
-
0025109821
-
Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases
-
2224783 10.1002/1097-0142(19901101)66:9<1873: AID-CNCR2820660904>3. 0.CO;2-5 1:STN:280:DyaK3M%2FivFSqsg%3D%3D
-
Jacquillat C, Khayat D, Banzet P, et al. Final report of the French multicenter phase II study of the nitrosourea fotemustine in 153 evaluable patients with disseminated malignant melanoma including patients with cerebral metastases. Cancer. 1990;66:1873-8.
-
(1990)
Cancer
, vol.66
, pp. 1873-1878
-
-
Jacquillat, C.1
Khayat, D.2
Banzet, P.3
-
36
-
-
81855183767
-
Fotemustine for the treatment of melanoma
-
22077794 10.1517/14656566.2011.633513
-
Quéreux G, Dréno B. Fotemustine for the treatment of melanoma. Expert Opin Pharmacother. 2011;12:2891-904.
-
(2011)
Expert Opin Pharmacother
, vol.12
, pp. 2891-2904
-
-
Quéreux, G.1
Dréno, B.2
-
37
-
-
84877735185
-
Fast FDA approval of melanoma drug
-
August 17 Available at Accessed on November 20, 2012
-
Wilson D, Fast FDA. approval of melanoma drug. The New York Times. August 17, 2011. Available at http://prescriptions.blogs.nytimes.com/2011/08/17/fast- f-d-a-approval-of-melanoma-drug/. Accessed on November 20, 2012
-
(2011)
The New York Times
-
-
Wilson, D.1
-
38
-
-
0346496097
-
CTLA-4 and tolerance: The biochemical point of view
-
14713717 10.1385/IR:28:3:241 1:CAS:528:DC%2BD2cXltVaisQ%3D%3D
-
Chikuma S, Bluestone JA. CTLA-4 and tolerance: the biochemical point of view. Immunol Res. 2003;28:241-53.
-
(2003)
Immunol Res
, vol.28
, pp. 241-253
-
-
Chikuma, S.1
Bluestone, J.A.2
-
39
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, dose-ranging study
-
20004617 10.1016/S1470-2045(09)70334-1 1:CAS:528:DC%2BC3cXhtlGgtbY%3D
-
Wolchok JD, Neyns B, Linette G, et al. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study. Lancet Oncol. 2010;11:155-64.
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
-
40
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
20525992 10.1056/NEJMoa1003466 1:CAS:528:DC%2BC3cXhtVCrtrbN
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-23.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
41
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
21639810 10.1056/NEJMoa1104621 1:CAS:528:DC%2BC3MXosVegtro%3D
-
Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364:2517-26.
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
42
-
-
84877744179
-
Ipilimumab improves survival in previously treated, advanced melanoma patients with poor prognostic factors: Subgroup analyses from a phase III trial
-
[Abstract 13240] Presented at
-
Lebbe C, McDermott DF, Robert C, et al. Ipilimumab improves survival in previously treated, advanced melanoma patients with poor prognostic factors: subgroup analyses from a phase III trial. [Abstract 13240] Presented at 35th ESMO Congress Milan, Italy October 8-12 2010.
-
(2010)
35th ESMO Congress Milan, Italy October 8-12
-
-
Lebbe, C.1
McDermott, D.F.2
Robert, C.3
-
43
-
-
69949095926
-
A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma
-
19671877 10.1158/1078-0432.CCR-09-1024 1:CAS:528:DC%2BD1MXhtVOntrbE
-
Weber J, Thompson JA, Hamid O, et al. A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma. Clin Cancer Res. 2009;15:5591-8.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5591-5598
-
-
Weber, J.1
Thompson, J.A.2
Hamid, O.3
-
44
-
-
84860446616
-
Ipilimumab in patients with melanoma and brain metastases: An open-label, phase 2 trial
-
10.1016/S1470-2045(12)70090-6 First prospective trial using ipilimumab in patients specifically with brain metastases from melanoma
-
Margolin K, Ernstoff MS, Hamid O, et al. Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial. Lancet Oncol. 2011;13:459-65. First prospective trial using ipilimumab in patients specifically with brain metastases from melanoma.
-
(2011)
Lancet Oncol
, vol.13
, pp. 459-465
-
-
Margolin, K.1
Ernstoff, M.S.2
Hamid, O.3
-
45
-
-
84859158384
-
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
-
22236695 10.1016/j.coi.2011.12.009 1:CAS:528:DC%2BC38XltValu7o%3D
-
Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol. 2012;24:207-12.
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
46
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
11015443 10.1084/jem.192.7.1027 1:CAS:528:DC%2BD3cXntFSlt7o%3D
-
Freeman GJ, Long AJ, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000;192:1027-34.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
47
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
11224527 10.1038/85330 1:CAS:528:DC%2BD3MXhvVaksrc%3D
-
Latchman Y, Wood CR, Chernova T, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol. 2001;2:261-8.
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
-
48
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
22658127 10.1056/NEJMoa1200690 1:CAS:528:DC%2BC38XhtV2rs7fN
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
49
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
22658128 10.1056/NEJMoa1200694 1:CAS:528:DC%2BC38XhtV2rsbnJ
-
Brahmer JR, Tykodi SS, Chow LQ, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med. 2012;366:2455-65.
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
50
-
-
84866665586
-
Tumor stem cell antigens as consolidative active specific immunotherapy: A randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma
-
22996370 10.1097/CJI.0b013e31826f79c8
-
Dillman RO, Cornforth AN, Depriest C, et al. Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma. J Immunother. 2012;35:641-9.
-
(2012)
J Immunother
, vol.35
, pp. 641-649
-
-
Dillman, R.O.1
Cornforth, A.N.2
Depriest, C.3
-
51
-
-
84865316603
-
Immunomodulating antibodies in the treatment of metastatic melanoma: The experience with anti-CTLA-4, anti-CD137, and anti-PD1
-
22524673 10.3109/1547691X.2012.678021 1:CAS:528:DC%2BC38Xht1ajsrnO
-
Simeone E, Ascierto PA. Immunomodulating antibodies in the treatment of metastatic melanoma: the experience with anti-CTLA-4, anti-CD137, and anti-PD1. J Immunotoxicol. 2012;9:241-7.
-
(2012)
J Immunotoxicol
, vol.9
, pp. 241-247
-
-
Simeone, E.1
Ascierto, P.A.2
-
52
-
-
78449237499
-
Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
-
21074066 10.1053/j.seminoncol.2010.09.008 1:CAS:528:DC%2BC3cXhsVWrur7P
-
Ascierto PA, Simeone E, Sznol M, Fu YX, Melero I. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol. 2010;37:508-16.
-
(2010)
Semin Oncol
, vol.37
, pp. 508-516
-
-
Ascierto, P.A.1
Simeone, E.2
Sznol, M.3
Fu, Y.X.4
Melero, I.5
-
53
-
-
84859447638
-
Adjuvant therapy for melanoma
-
22453021 10.1097/PPO.0b013e31824f118b 1:CAS:528:DC%2BC38XnsFCqsrY%3D
-
Davar D, Tarhini AA, Kirkwood JM. Adjuvant therapy for melanoma. Cancer J. 2012;18:192-202.
-
(2012)
Cancer J
, vol.18
, pp. 192-202
-
-
Davar, D.1
Tarhini, A.A.2
Kirkwood, J.M.3
-
54
-
-
84869212118
-
Long-Term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma
-
23008300 10.1200/JCO.2011.41.3799 1:CAS:528:DC%2BC3sXosVCksg%3D%3D
-
Eggermont AM, Suciu S, Testori A, et al. Long-Term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma. J Clin Oncol. 2012;30:3810-8.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3810-3818
-
-
Eggermont, A.M.1
Suciu, S.2
Testori, A.3
-
55
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
16291983 10.1056/NEJMoa050092 1:CAS:528:DC%2BD2MXht1ajtLjP
-
Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med. 2005;353:2135-47.
-
(2005)
N Engl J Med
, vol.353
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
-
56
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
21639808 10.1056/NEJMoa1103782 1:CAS:528:DC%2BC3MXosVeitbs%3D
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
57
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
22356324 10.1056/NEJMoa1112302 1:CAS:528:DC%2BC38XjtFOqtr0%3D
-
Sosman JA, Kim KB, Schuchter L, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med. 2012;366:707-14.
-
(2012)
N Engl J Med
, vol.366
, pp. 707-714
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
-
58
-
-
84855179546
-
Vemurafenib for melanoma metastases to the brain
-
22188003 10.1056/NEJMc1111672 1:CAS:528:DC%2BC38XmvVKhsA%3D%3D Initial case report showing potential efficacy of vemurafenib in a patient with melanoma brain metastases
-
Rochet NM, Kottschade LA, Markovic SN. Vemurafenib for melanoma metastases to the brain. N Engl J Med. 2011;365:2439-41. Initial case report showing potential efficacy of vemurafenib in a patient with melanoma brain metastases.
-
(2011)
N Engl J Med
, vol.365
, pp. 2439-2441
-
-
Rochet, N.M.1
Kottschade, L.A.2
Markovic, S.N.3
-
59
-
-
84877752620
-
An open-label pilot study of vemurafenib in previously treated metastatic melanoma patients with brain metastases
-
[abstract 8548]. Presented at
-
Dummer R, Rinderknecht J, Goldinger SM, et al. An open-label pilot study of vemurafenib in previously treated metastatic melanoma patients with brain metastases. [abstract 8548]. Presented at ASCO 2011 Chicago, Illinois; June 3-7 2011.
-
(2011)
ASCO 2011 Chicago, Illinois; June 3-7
-
-
Dummer, R.1
Rinderknecht, J.2
Goldinger, S.M.3
-
60
-
-
84861381332
-
Adaptive upregulation of FOXD3 and resistance to PLX4032/ 4720-induced cell death in mutant B-RAF melanoma cells
-
21996740 10.1038/onc.2011.424 1:CAS:528:DC%2BC38XmvVCjtr4%3D
-
Basile KJ, Abel EV, Aplin AE. Adaptive upregulation of FOXD3 and resistance to PLX4032/ 4720-induced cell death in mutant B-RAF melanoma cells. Oncogene. 2012;31:2471-9.
-
(2012)
Oncogene
, vol.31
, pp. 2471-2479
-
-
Basile, K.J.1
Abel, E.V.2
Aplin, A.E.3
-
61
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
-
22608338 10.1016/S0140-6736(12)60398-5 1:CAS:528:DC%2BC38Xnt1Kmtbo%3D Phase I prospective trial using dabrafenib in patients with brain metastases. It is important because it does not exclude patients with brain metastases, as traditionally is done in other Phase I trials of new drugs
-
Falchook GS, Long GV, Kurzrock R. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet. 2012;379:1893-901. Phase I prospective trial using dabrafenib in patients with brain metastases. It is important because it does not exclude patients with brain metastases, as traditionally is done in other Phase I trials of new drugs.
-
(2012)
Lancet
, vol.379
, pp. 1893-1901
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
-
62
-
-
84868120907
-
Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): A multicentre, open-label, phase 2 trial
-
Long GV, Trefzer U, Davies MA, et al. Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial. Lancet Oncol 2012, 1470-2045. This paper is an important study of dabrafenib and provides information on efficacy in patients with metastatic melanoma to the brain with different BRAF mutations.
-
(2012)
Lancet Oncol
, pp. 1470-2045
-
-
Long, G.V.1
Trefzer, U.2
Davies, M.A.3
-
63
-
-
84864371119
-
Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: A phase 1 dose-escalation trial
-
10.1016/S1470-2045(12)70269-3
-
Falchook GS, Lewis KD, Infante JR, et al. Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial. Lancet Oncol. 2012;8:782-9.
-
(2012)
Lancet Oncol
, vol.8
, pp. 782-789
-
-
Falchook, G.S.1
Lewis, K.D.2
Infante, J.R.3
-
65
-
-
84867772278
-
Melanoma brain metastasis: Overview of current management and emerging targeted therapies
-
23082737 10.1586/ern.12.111 1:CAS:528:DC%2BC38XhsFekur3K
-
Fonkem E, Uhlmann EJ, Floyd SR, et al. Melanoma brain metastasis: overview of current management and emerging targeted therapies. Expert Rev Neurother. 2012;12:1207-15.
-
(2012)
Expert Rev Neurother
, vol.12
, pp. 1207-1215
-
-
Fonkem, E.1
Uhlmann, E.J.2
Floyd, S.R.3
-
66
-
-
79959975634
-
Does metastasectomy improve survival in patients with Stage IV melanoma? A cancer registry analysis of outcomes
-
21381040 10.1002/jso.21903
-
Wasif N, Bagaria SP, Ray P, Morton DL. Does metastasectomy improve survival in patients with Stage IV melanoma? A cancer registry analysis of outcomes. J Surg Oncol. 2011;104:111-5.
-
(2011)
J Surg Oncol
, vol.104
, pp. 111-115
-
-
Wasif, N.1
Bagaria, S.P.2
Ray, P.3
Morton, D.L.4
-
67
-
-
0022545434
-
Surgery as palliative treatment for distant metastases of melanoma
-
2427043 10.1097/00000658-198608000-00013
-
Wornom 3rd IL, Smith JW, Soong SJ, et al. Surgery as palliative treatment for distant metastases of melanoma. Ann Surg. 1986;204:181-5.
-
(1986)
Ann Surg
, vol.204
, pp. 181-185
-
-
Wornom III, I.L.1
Smith, J.W.2
Soong, S.J.3
-
68
-
-
80051988510
-
A Phase 2 Trial of Complete Resection for Stage IV Melanoma Results of Southwest Oncology Group Clinical Trial S9430
-
Sosman JA, Moon J, Tuthil R, et al.: A Phase 2 Trial of Complete Resection for Stage IV Melanoma Results of Southwest Oncology Group Clinical Trial S9430. Cancer 2011, 4740-6. This paper prospectively looked at 66 patients with Stage IV melanoma for outcomes after surgical resection. This paper found that surgical resection prolonged survival.
-
(2011)
Cancer
, pp. 4740-4746
-
-
Sosman, J.A.1
Moon, J.2
Tuthil, R.3
-
69
-
-
44449179930
-
Guidelines for the initial management of metastatic brain tumors: Role of surgery, radiosurgery, and radiation therapy
-
18492462
-
Ewend MG, Morris DE, Carey LA, et al. Guidelines for the initial management of metastatic brain tumors: role of surgery, radiosurgery, and radiation therapy. J Natl Compr Canc Netw. 2008;6:505-13.
-
(2008)
J Natl Compr Canc Netw
, vol.6
, pp. 505-513
-
-
Ewend, M.G.1
Morris, D.E.2
Carey, L.A.3
-
70
-
-
78649461907
-
Metastasectomy for stage IV melanoma: For whom and how much?
-
21111963 10.1016/j.soc.2010.09.010
-
Caudle AS, Ross MI. Metastasectomy for stage IV melanoma: for whom and how much? Surg Oncol Clin N Am. 2011;20:133-44.
-
(2011)
Surg Oncol Clin N Am
, vol.20
, pp. 133-144
-
-
Caudle, A.S.1
Ross, M.I.2
-
71
-
-
84859471907
-
Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: Current status and future outlook
-
22453018 10.1097/PPO.0b013e31824d4465 1:CAS:528:DC%2BC38XnsFCqsrg%3D
-
Wu R, Forget MA, Chacon J, et al. Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook. Cancer J. 2012;18:160-75.
-
(2012)
Cancer J
, vol.18
, pp. 160-175
-
-
Wu, R.1
Forget, M.A.2
Chacon, J.3
-
72
-
-
34250184652
-
Stereotactic radiosurgery alone versus resection plus whole-brain radiotherapy for 1 or 2 brain metastases in recursive partitioning analysis class 1 and 2 patients
-
17487853 10.1002/cncr.22729
-
Rades D, Bohlen G, Pluemer A, et al. Stereotactic radiosurgery alone versus resection plus whole-brain radiotherapy for 1 or 2 brain metastases in recursive partitioning analysis class 1 and 2 patients. Cancer. 2007;109:2515-21.
-
(2007)
Cancer
, vol.109
, pp. 2515-2521
-
-
Rades, D.1
Bohlen, G.2
Pluemer, A.3
-
73
-
-
71249157772
-
Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: A randomised controlled trial
-
19801201 10.1016/S1470-2045(09)70263-3 Patients with brain metastases were randomized to receive either radiosurgery alone or radiosurgery and WBRT. A greater cognitive decline was seen in patients receiving WBRT pointing to a serious risk of this treatment
-
Chang EL, Wefel JS, Hess KR, et al. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol. 2009;10:1037-44. Patients with brain metastases were randomized to receive either radiosurgery alone or radiosurgery and WBRT. A greater cognitive decline was seen in patients receiving WBRT pointing to a serious risk of this treatment.
-
(2009)
Lancet Oncol
, vol.10
, pp. 1037-1044
-
-
Chang, E.L.1
Wefel, J.S.2
Hess, K.R.3
-
74
-
-
3042559645
-
Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases
-
15234044 10.1016/j.ijrobp.2003.12.037
-
Selek U, Chang EL, Hassenbusch 3rd SJ, et al. Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases. Int J Radiat Oncol Biol Phys. 2004;59:1097-106.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.59
, pp. 1097-1106
-
-
Selek, U.1
Chang, E.L.2
Hassenbusch III, S.J.3
-
75
-
-
0036535339
-
Metastatic melanoma to the brain: Prognostic factors after gamma knife radiosurgery
-
11955740 10.1016/S0360-3016(01)02772-9
-
Yu C, Chen JC, Apuzzo ML, et al. Metastatic melanoma to the brain: prognostic factors after gamma knife radiosurgery. Int J Radiat Oncol Biol Phys. 2002;52:1277-87.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.52
, pp. 1277-1287
-
-
Yu, C.1
Chen, J.C.2
Apuzzo, M.L.3
-
76
-
-
0019943676
-
The radioresponsiveness of melanoma
-
7118615 10.1016/0360-3016(82)90060-8 1:STN:280:DyaL3s%2Fgs1KlsQ%3D%3D
-
Doss LL, Memula N. The radioresponsiveness of melanoma. Int J Radiat Oncol Biol Phys. 1982;8:1131-4.
-
(1982)
Int J Radiat Oncol Biol Phys
, vol.8
, pp. 1131-1134
-
-
Doss, L.L.1
Memula, N.2
-
77
-
-
84864456883
-
Efficacy and toxicity of whole brain radiotherapy in patients with multiple cerebral metastases from malignant melanoma
-
10.1186/1748-717X-7-130
-
Hauswald H, Dittmar JO, Habermehl D, et al. Efficacy and toxicity of whole brain radiotherapy in patients with multiple cerebral metastases from malignant melanoma. Radiat Oncol. 2012;2:130.
-
(2012)
Radiat Oncol
, vol.2
, pp. 130
-
-
Hauswald, H.1
Dittmar, J.O.2
Habermehl, D.3
-
78
-
-
77952585016
-
Estimated risk of perihippocampal disease progression after hippocampal avoidance during whole-brain radiotherapy: Safety profile for RTOG 0933
-
20392503 10.1016/j.radonc.2010.02.030
-
Gondi V, Tome WA, Marsh J, et al. Estimated risk of perihippocampal disease progression after hippocampal avoidance during whole-brain radiotherapy: safety profile for RTOG 0933. Radiother Oncol. 2010;95:327-31.
-
(2010)
Radiother Oncol
, vol.95
, pp. 327-331
-
-
Gondi, V.1
Tome, W.A.2
Marsh, J.3
-
79
-
-
34247634463
-
Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS)
-
17351953 10.1002/cncr.22605
-
Samlowski WE, Watson GA, Wang M, Rao G, Klimo Jr P, Boucher K, et al. Multimodality treatment of melanoma brain metastases incorporating stereotactic radiosurgery (SRS). Cancer. 2007;109:1855-62.
-
(2007)
Cancer
, vol.109
, pp. 1855-1862
-
-
Samlowski, W.E.1
Watson, G.A.2
Wang, M.3
Rao, G.4
Klimo, Jr.P.5
Boucher, K.6
-
80
-
-
79951966253
-
Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: Results of the EORTC 22952-26001 study
-
21041710 10.1200/JCO.2010.30.1655 This paper published the results of a phase III trial looking at the effect of adding WBRT to treatment for patients with brain metastases. It found decreased local recurrence but no increase in survival
-
Kocher M, Soffietti R, Abacioglu U, et al. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol. 2011;29:134-41. This paper published the results of a phase III trial looking at the effect of adding WBRT to treatment for patients with brain metastases. It found decreased local recurrence but no increase in survival.
-
(2011)
J Clin Oncol
, vol.29
, pp. 134-141
-
-
Kocher, M.1
Soffietti, R.2
Abacioglu, U.3
-
81
-
-
77954980532
-
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases
-
Patil CG, Pricola K, Sarmiento JM, et al. Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases. Cochrane Database Syst Rev. 2012;12:9.
-
(2012)
Cochrane Database Syst Rev
, vol.12
, pp. 9
-
-
Patil, C.G.1
Pricola, K.2
Sarmiento, J.M.3
-
82
-
-
18944380115
-
Surgical resection and whole brain radiation therapy versus whole-brain radiation therapy alone for single brain metastases
-
Hart MG, Grant R, Walker M, Dickinson HO. Surgical resection and whole brain radiation therapy versus whole-brain radiation therapy alone for single brain metastases. Cochrane Database Syst Rev. 2005;25(1):CD003292.
-
(2005)
Cochrane Database Syst Rev
, vol.25
, Issue.1
, pp. 003292
-
-
Hart, M.G.1
Grant, R.2
Walker, M.3
Dickinson, H.O.4
-
83
-
-
33744954692
-
Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: A randomized controlled trial
-
16757720 10.1001/jama.295.21.2483 1:CAS:528:DC%2BD28XlsV2ltbo%3D
-
Aoyama H, Shirato H, Tago M, et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA. 2006;295:2483-91.
-
(2006)
JAMA
, vol.295
, pp. 2483-2491
-
-
Aoyama, H.1
Shirato, H.2
Tago, M.3
-
84
-
-
79957967246
-
Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - A randomised phase III trial
-
21496312 10.1186/1471-2407-11-142 This study is similar to Kocher et al. but will look specifically at the outcome in patients with melanoma, which is an understudied population of patients
-
Fogarty G, Morton RL, Vardy J, et al. Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial. BMC Cancer. 2011;11:142-50. This study is similar to Kocher et al. but will look specifically at the outcome in patients with melanoma, which is an understudied population of patients.
-
(2011)
BMC Cancer
, vol.11
, pp. 142-150
-
-
Fogarty, G.1
Morton, R.L.2
Vardy, J.3
-
85
-
-
84865567547
-
Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): An open-label, single-arm phase 2 trial
-
22894884 10.1016/S1470-2045(12)70324-8 Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): An open-label, single-arm phase 2 trial
-
Di Giacomo AM, Ascierto PA, Pilla L, et al. Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial. Lancet Oncol. 2012;13:879-86. Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): An open-label, single-arm phase 2 trial.
-
(2012)
Lancet Oncol
, vol.13
, pp. 879-886
-
-
Di Giacomo, A.M.1
Ascierto, P.A.2
Pilla, L.3
-
86
-
-
84864559660
-
Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival
-
22702482 10.3171/2012.5.JNS111929 Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival
-
Knisely JP, Yu JB, Flanigan J, et al. Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival. J Neurosurg. 2012;117:227-33. Radiosurgery for melanoma brain metastases in the ipilimumab era and the possibility of longer survival.
-
(2012)
J Neurosurg
, vol.117
, pp. 227-233
-
-
Knisely, J.P.1
Yu, J.B.2
Flanigan, J.3
-
87
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
22397654 10.1056/NEJMoa1112824 1:CAS:528:DC%2BC38XktFOgurw%3D
-
Postow MA, Callahan MK, Barker CA, et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med. 2012;366:925-31.
-
(2012)
N Engl J Med
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
-
88
-
-
84872202826
-
The abscopal effect associated with a systemic anti-melanoma immune response
-
(In press)
-
Stamell EF, Wolchok JD, Gnjatic S, et al. The abscopal effect associated with a systemic anti-melanoma immune response. Int J Radiat Oncol Biol Phys 2012 (In press).
-
(2012)
Int J Radiat Oncol Biol Phys
-
-
Stamell, E.F.1
Wolchok, J.D.2
Gnjatic, S.3
-
90
-
-
84856297823
-
Cost-effectiveness analysis of a randomized study comparing radiosurgery with radiosurgery and whole brain radiation therapy in patients with 1 to 3 brain metastases
-
21293245 10.1097/COC.0b013e3182005a8f
-
Lal LS, Byfield SD, Chang EL, et al. Cost-effectiveness analysis of a randomized study comparing radiosurgery with radiosurgery and whole brain radiation therapy in patients with 1 to 3 brain metastases. Am J Clin Oncol. 2012;35:45-50.
-
(2012)
Am J Clin Oncol
, vol.35
, pp. 45-50
-
-
Lal, L.S.1
Byfield, S.D.2
Chang, E.L.3
|