-
1
-
-
1542611579
-
Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma
-
Lens MB, Dawes M. Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma. Br. J. Dermatol. 150(2), 179-185 (2004).
-
(2004)
Br. J. Dermatol
, vol.150
, Issue.2
, pp. 179-185
-
-
Lens, M.B.1
Dawes, M.2
-
2
-
-
0031975369
-
Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma
-
Sampson JH, Carter JH Jr, Friedman AH, Seigler HF. Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma. J. Neurosurg. 88(1), 11-20 (1998).
-
(1998)
J. Neurosurg
, vol.88
, Issue.1
, pp. 11-20
-
-
Sampson, J.H.1
Carter, J.H.2
Friedman, A.H.3
Seigler, H.F.4
-
3
-
-
0021244098
-
Malignant melanoma brain metastases review of roswell park memorial institute experience
-
Madajewicz S, Karakousis C, West CR, Caracandas J, Avellanosa AM. Malignant melanoma brain metastases. Review of Roswell Park Memorial Institute experience. Cancer 53(11), 2550-2552 (1984).
-
(1984)
Cancer
, vol.53
, Issue.11
, pp. 2550-2552
-
-
Madajewicz, S.1
Karakousis, C.2
West, C.R.3
Caracandas, J.4
Avellanosa, A.M.5
-
4
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 61(5), 759-767 (1990).
-
(1990)
Cell
, vol.61
, Issue.5
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
6
-
-
0032568258
-
CDKN2A mutations in multiple primary melanomas
-
Monzon J, Liu L, Brill H et al. CDKN2A mutations in multiple primary melanomas. N. Engl. J. Med. 338(13), 879-887 (1998).
-
(1998)
N. Engl. J. Med
, vol.338
, Issue.13
, pp. 879-887
-
-
Monzon, J.1
Liu, L.2
Brill, H.3
-
7
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
BRIM-3 Study Group
-
Chapman PB, Hauschild A, Robert C et al.; BRIM-3 Study Group. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N. Engl. J. Med. 364(26), 2507-2516 (2011).
-
(2011)
N. Engl. J. Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
8
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N. Engl. J. Med. 363(9), 809-819 (2010).
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
9
-
-
79953151458
-
Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
-
Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion. Science 331(6024), 1565-1570 (2011).
-
(2011)
Science 331
, vol.6024
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
10
-
-
4344694453
-
Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
-
Barnholtz-Sloan JS, Sloan AE, Davis FG, Vigneau FD, Lai P, Sawaya RE. Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System. J. Clin. Oncol. 22(14), 2865-2872 (2004).
-
(2004)
J. Clin. Oncol
, vol.22
, Issue.14
, pp. 2865-2872
-
-
Barnholtz-Sloan, J.S.1
Sloan, A.E.2
Davis, F.G.3
Vigneau, F.D.4
Lai, P.5
Sawaya, R.E.6
-
11
-
-
0037093972
-
Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma
-
Schouten LJ, Rutten J, Huveneers HA, Twijnstra A. Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma. Cancer 94(10), 2698-2705 (2002).
-
(2002)
Cancer
, vol.94
, Issue.10
, pp. 2698-2705
-
-
Schouten, L.J.1
Rutten, J.2
Huveneers, H.A.3
Twijnstra, A.4
-
12
-
-
0018096512
-
Malignant melanoma and central nervous system metastases: Incidence, diagnosis, treatment and survival
-
Amer MH, Al-Sarraf M, Baker LH, Vaitkevicius VK. Malignant melanoma and central nervous system metastases: Incidence, diagnosis, treatment and survival. Cancer 42(2), 660-668 (1978).
-
(1978)
Cancer
, vol.42
, Issue.2
, pp. 660-668
-
-
Amer, M.H.1
Al-Sarraf, M.2
Baker, L.H.3
Vaitkevicius, V.K.4
-
13
-
-
0018102908
-
Metastatic pattern of malignant melanoma a study of 216 autopsy cases
-
Patel JK, Didolkar MS, Pickren JW, Moore RH. Metastatic pattern of malignant melanoma. A study of 216 autopsy cases. Am. J. Surg. 135(6), 807-810 (1978).
-
(1978)
Am. J. Surg
, vol.135
, Issue.6
, pp. 807-810
-
-
Patel, J.K.1
Didolkar, M.S.2
Pickren, J.W.3
Moore, R.H.4
-
14
-
-
81855163404
-
Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma
-
Bedikian AY, Wei C, Detry M et al. Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma. Am. J. Clin. Oncol. 34(6), 603-610 (2011).
-
(2011)
Am. J. Clin. Oncol
, vol.34
, Issue.6
, pp. 603-610
-
-
Bedikian, A.Y.1
Wei, C.2
Detry, M.3
-
15
-
-
0028951043
-
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
-
Holmgren L, O'Reilly MS, Folkman J. Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat. Med. 1(2), 149-153 (1995).
-
(1995)
Nat. Med
, vol.1
, Issue.2
, pp. 149-153
-
-
Holmgren, L.1
O'Reilly, M.S.2
Folkman, J.3
-
17
-
-
84856691346
-
A systematic approach to the management of patients with brain metastases of known or unknown primary site
-
Kyritsis AP, Markoula S, Levin VA. A systematic approach to the management of patients with brain metastases of known or unknown primary site. Cancer Chemother. Pharmacol. 69(1), 1-13 (2012).
-
(2012)
Cancer Chemother. Pharmacol
, vol.69
, Issue.1
, pp. 1-13
-
-
Kyritsis, A.P.1
Markoula, S.2
Levin, V.A.3
-
18
-
-
0345293093
-
Treatment of brain metastases from melanoma
-
McWilliams RR, Brown PD, Buckner JC, Link MJ, Markovic SN. Treatment of brain metastases from melanoma. Mayo Clin. Proc. 78(12), 1529-1536 (2003).
-
(2003)
Mayo Clin. Proc
, vol.78
, Issue.12
, pp. 1529-1536
-
-
McWilliams, R.R.1
Brown, P.D.2
Buckner, J.C.3
Link, M.J.4
Markovic, S.N.5
-
19
-
-
67650529123
-
Diagnosis and treatment of melanoma brain metastasis: A literature review
-
Sloan AE, Nock CJ, Einstein DB. Diagnosis and treatment of melanoma brain metastasis: A literature review. Cancer Control 16(3), 248-255 (2009).
-
(2009)
Cancer Control
, vol.16
, Issue.3
, pp. 248-255
-
-
Sloan, A.E.1
Nock, C.J.2
Einstein, D.B.3
-
20
-
-
0032483685
-
Postoperative radiotherapy in the treatment of single metastases to the brain: A randomized trial
-
Patchell RA, Tibbs PA, Regine WF et al. Postoperative radiotherapy in the treatment of single metastases to the brain: A randomized trial. JAMA 280(17), 1485-1489 (1998).
-
(1998)
JAMA
, vol.280
, Issue.17
, pp. 1485-1489
-
-
Patchell, R.A.1
Tibbs, P.A.2
Regine, W.F.3
-
21
-
-
0025189608
-
A randomized trial of surgery in the treatment of single metastases to the brain
-
Patchell RA, Tibbs PA, Walsh JW et al. A randomized trial of surgery in the treatment of single metastases to the brain. N. Engl. J. Med. 322(8), 494-500 (1990).
-
(1990)
N. Engl. J. Med
, vol.322
, Issue.8
, pp. 494-500
-
-
Patchell, R.A.1
Tibbs, P.A.2
Walsh, J.W.3
-
22
-
-
44849122610
-
Brain and leptomeningeal metastases from cutaneous melanoma: Survival outcomes based on clinical features
-
Raizer JJ, Hwu WJ, Panageas KS et al. Brain and leptomeningeal metastases from cutaneous melanoma: Survival outcomes based on clinical features. Neuro-oncology 10(2), 199-207 (2008).
-
(2008)
Neuro-oncology
, vol.10
, Issue.2
, pp. 199-207
-
-
Raizer, J.J.1
Hwu, W.J.2
Panageas, K.S.3
-
23
-
-
0019416621
-
Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy
-
Fertil B, Malaise EP. Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 7(5), 621-629 (1981).
-
(1981)
Int. J. Radiat. Oncol. Biol. Phys
, vol.7
, Issue.5
, pp. 621-629
-
-
Fertil, B.1
Malaise, E.P.2
-
24
-
-
0022363207
-
Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves
-
Fertil B, Malaise EP. Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves. Int. J. Radiat. Oncol. Biol. Phys. 11(9), 1699-1707 (1985).
-
(1985)
Int. J. Radiat. Oncol. Biol. Phys
, vol.11
, Issue.9
, pp. 1699-1707
-
-
Fertil, B.1
Malaise, E.P.2
-
25
-
-
79956124754
-
Can current prognostic scores reliably guide treatment decisions in patients with brain metastases from malignant melanoma
-
Nieder C, Marienhagen K, Geinitz H, Grosu AL. Can current prognostic scores reliably guide treatment decisions in patients with brain metastases from malignant melanoma? J. Cancer Res. Ther. 7(1), 47-51 (2011).
-
(2011)
J. Cancer Res. Ther
, vol.7
, Issue.1
, pp. 47-51
-
-
Nieder, C.1
Marienhagen, K.2
Geinitz, H.3
Grosu, A.L.4
-
26
-
-
0023774852
-
Palliative radiotherapy for metastatic malignant melanoma: Brain metastases, bone metastases, and spinal cord compression
-
Rate WR, Solin LJ, Turrisi AT. Palliative radiotherapy for metastatic malignant melanoma: Brain metastases, bone metastases, and spinal cord compression. Int. J. Radiat. Oncol. Biol. Phys. 15(4), 859-864 (1988).
-
(1988)
Int. J. Radiat. Oncol. Biol. Phys
, vol.15
, Issue.4
, pp. 859-864
-
-
Rate, W.R.1
Solin, L.J.2
Turrisi, A.T.3
-
27
-
-
0023620038
-
Adjuvant radiation therapy after surgical resection of solitary brain metastasis: Association with pattern of failure and survival
-
Smalley SR, Schray MF, Laws ER Jr, O'Fallon Jr. Adjuvant radiation therapy after surgical resection of solitary brain metastasis: Association with pattern of failure and survival. Int. J. Radiat. Oncol. Biol. Phys. 13(11), 1611-1616 (1987).
-
(1987)
Int. J. Radiat. Oncol. Biol. Phys
, vol.13
, Issue.11
, pp. 1611-1616
-
-
Smalley, S.R.1
Schray, M.F.2
Laws, E.R..3
O'Fallon, J.R.4
-
28
-
-
55749092775
-
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: A Phase II Cytokine Working Group study
-
Atkins MB, Sosman JA, Agarwala S et al. Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: A Phase II Cytokine Working Group study. Cancer 113(8), 2139-2145 (2008).
-
(2008)
Cancer
, vol.113
, Issue.8
, pp. 2139-2145
-
-
Atkins, M.B.1
Sosman, J.A.2
Agarwala, S.3
-
29
-
-
0036208833
-
Temozolomide and whole brain irradiation in melanoma metastatic to the brain: A phase ii trial of the cytokine working group
-
Margolin K, Atkins B, Thompson A et al. Temozolomide and whole brain irradiation in melanoma metastatic to the brain: A Phase II trial of the Cytokine Working Group. J. Cancer Res. Clin. Oncol. 128(4), 214-218 (2002).
-
(2002)
J. Cancer Res. Clin. Oncol
, vol.128
, Issue.4
, pp. 214-218
-
-
Margolin, K.1
Atkins, B.2
Thompson, A.3
-
30
-
-
0026021186
-
Fraction size in external beam radiation therapy in the treatment of melanoma
-
Sause WT, Cooper JS, Rush S et al. Fraction size in external beam radiation therapy in the treatment of melanoma. Int. J. Radiat. Oncol. Biol. Phys. 20(3), 429-432 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys
, vol.20
, Issue.3
, pp. 429-432
-
-
Sause, W.T.1
Cooper, J.S.2
Rush, S.3
-
31
-
-
84863020427
-
Summary report on the graded prognostic assessment: An accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases
-
Sperduto PW, Kased N, Roberge D et al. Summary report on the graded prognostic assessment: An accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases. J. Clin. Oncol. 30(4), 419-425 (2012).
-
(2012)
J. Clin. Oncol
, vol.30
, Issue.4
, pp. 419-425
-
-
Sperduto, P.W.1
Kased, N.2
Roberge, D.3
-
32
-
-
0028209414
-
Stereotactic radiosurgery: A review and comparison of methods
-
Phillips MH, Stelzer KJ, Griffin TW, Mayberg MR, Winn HR. Stereotactic radiosurgery: A review and comparison of methods. J. Clin. Oncol. 12(5), 1085-1099 (1994).
-
(1994)
J. Clin. Oncol
, vol.12
, Issue.5
, pp. 1085-1099
-
-
Phillips, M.H.1
Stelzer, K.J.2
Griffin, T.W.3
Mayberg, M.R.4
Winn, H.R.5
-
33
-
-
3042559645
-
Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases
-
Selek U, Chang EL, Hassenbusch SJ 3rd et al. Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases. Int. J. Radiat. Oncol. Biol. Phys. 59(4), 1097-1106 (2004).
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys
, vol.59
, Issue.4
, pp. 1097-1106
-
-
Selek, U.1
Chang, E.L.2
Hassenbusch III, S.J.3
-
34
-
-
58949097456
-
Gamma knife surgery in the management of radioresistant brain metastases in high-risk patients with melanoma, renal cell carcinoma, and sarcoma
-
Powell JW, Chung CT, Shah HR et al. Gamma knife surgery in the management of radioresistant brain metastases in high-risk patients with melanoma, renal cell carcinoma, and sarcoma. J. Neurosurg. 109(Suppl.), 122-128 (2008).
-
(2008)
J. Neurosurg
, vol.109
, Issue.SUPPL.
, pp. 122-128
-
-
Powell, J.W.1
Chung, C.T.2
Shah, H.R.3
-
35
-
-
2442713678
-
Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: Phase III results of the RTOG 9508 randomised trial
-
Andrews DW, Scott CB, Sperduto PW et al. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: Phase III results of the RTOG 9508 randomised trial. Lancet 363(9422), 1665-1672 (2004).
-
(2004)
Lancet
, vol.363
, Issue.9422
, pp. 1665-1672
-
-
Andrews, D.W.1
Scott, C.B.2
Sperduto, P.W.3
-
36
-
-
77952567992
-
Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: A multi-institutional analysis of 4,259 patients
-
Sperduto PW, Chao ST, Sneed PK et al. Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: A multi-institutional analysis of 4,259 patients. Int. J. Radiat. Oncol. Biol. Phys. 77(3), 655-661 (2010).
-
(2010)
Int. J. Radiat. Oncol. Biol. Phys
, vol.77
, Issue.3
, pp. 655-661
-
-
Sperduto, P.W.1
Chao, S.T.2
Sneed, P.K.3
-
37
-
-
2942689983
-
Temozolomide for the treatment of brain metastases associated with metastatic melanoma: A Phase II study
-
Agarwala SS, Kirkwood JM, Gore M et al. Temozolomide for the treatment of brain metastases associated with metastatic melanoma: A Phase II study. J. Clin. Oncol. 22(11), 2101-2107 (2004).
-
(2004)
J. Clin. Oncol
, vol.22
, Issue.11
, pp. 2101-2107
-
-
Agarwala, S.S.1
Kirkwood, J.M.2
Gore, M.3
-
38
-
-
33846205132
-
Temozolomide in advanced malignant melanoma with small brain metastases: Can we withhold cranial irradiation
-
Boogerd W, de Gast GC, Dalesio O. Temozolomide in advanced malignant melanoma with small brain metastases: Can we withhold cranial irradiation? Cancer 109(2), 306-312 (2007).
-
(2007)
Cancer
, vol.109
, Issue.2
, pp. 306-312
-
-
Boogerd, W.1
De Gast, G.C.2
Dalesio, O.3
-
39
-
-
0036731532
-
Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases
-
Antonadou D, Paraskevaidis M, Sarris G et al. Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases. J. Clin. Oncol. 20(17), 3644-3650 (2002).
-
(2002)
J. Clin. Oncol
, vol.20
, Issue.17
, pp. 3644-3650
-
-
Antonadou, D.1
Paraskevaidis, M.2
Sarris, G.3
-
40
-
-
30944464394
-
Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases
-
Hofmann M, Kiecker F, Wurm R et al. Temozolomide with or without radiotherapy in melanoma with unresectable brain metastases. J. Neurooncol. 76(1), 59-64 (2006).
-
(2006)
J. Neurooncol
, vol.76
, Issue.1
, pp. 59-64
-
-
Hofmann, M.1
Kiecker, F.2
Wurm, R.3
-
41
-
-
20444387198
-
Temozolomide plus thalidomide in patients with brain metastases from melanoma: A Phase II study
-
Hwu WJ, Lis E, Menell JH et al. Temozolomide plus thalidomide in patients with brain metastases from melanoma: A Phase II study. Cancer 103(12), 2590-2597 (2005).
-
(2005)
Cancer
, vol.103
, Issue.12
, pp. 2590-2597
-
-
Hwu, W.J.1
Lis, E.2
Menell, J.H.3
-
42
-
-
73349121946
-
Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases
-
Amaravadi RK, Schuchter LM, McDermott DF et al. Phase II trial of temozolomide and sorafenib in advanced melanoma patients with or without brain metastases. Clin. Cancer Res. 15(24), 7711-7718 (2009).
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.24
, pp. 7711-7718
-
-
Amaravadi, R.K.1
Schuchter, L.M.2
McDermott, D.F.3
-
43
-
-
20244384262
-
Chemotherapy by fotemustine in cerebral metastases of disseminated malignant melanoma
-
Jacquillat C, Khayat D, Banzet P et al. Chemotherapy by fotemustine in cerebral metastases of disseminated malignant melanoma. Cancer Chemother. Pharmacol. 25(4), 263-266 (1990).
-
(1990)
Cancer Chemother. Pharmacol
, vol.25
, Issue.4
, pp. 263-266
-
-
Jacquillat, C.1
Khayat, D.2
Banzet, P.3
-
44
-
-
0026013307
-
A Phase II study of taxol in patients with malignant melanoma
-
Einzig AI, Hochster H, Wiernik PH et al. A Phase II study of taxol in patients with malignant melanoma. Invest. New Drugs 9(1), 59-64 (1991).
-
(1991)
Invest. New Drugs
, vol.9
, Issue.1
, pp. 59-64
-
-
Einzig, A.I.1
Hochster, H.2
Wiernik, P.H.3
-
45
-
-
0036301503
-
CTLA-4: New insights into its biological function and use in tumor immunotherapy
-
Egen JG, Kuhns MS, Allison JP. CTLA-4: New insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3(7), 611-618 (2002).
-
(2002)
Nat. Immunol
, vol.3
, Issue.7
, pp. 611-618
-
-
Egen, J.G.1
Kuhns, M.S.2
Allison, J.P.3
-
46
-
-
58049202334
-
Phase I/II study of ipilimumab for patients with metastatic melanoma
-
Weber JS, O'Day S, Urba W et al. Phase I/II study of ipilimumab for patients with metastatic melanoma. J. Clin. Oncol. 26(36), 5950-5956 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
, Issue.36
, pp. 5950-5956
-
-
Weber, J.S.1
O'Day, S.2
Urba, W.3
-
47
-
-
78650439466
-
Ipilimumab efficacy and safety in patients with advanced melanoma: A retrospective analysis of HLA subtype from four trials
-
Wolchok JD, Weber JS, Hamid O et al. Ipilimumab efficacy and safety in patients with advanced melanoma: A retrospective analysis of HLA subtype from four trials. Cancer Immun. 10, 9 (2010).
-
(2010)
Cancer Immun
, vol.10
, Issue.9
-
-
Wolchok, J.D.1
Weber, J.S.2
Hamid, O.3
-
48
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010).
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
49
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364(26), 2517-2526 (2011).
-
(2011)
N. Engl. J. Med
, vol.364
, Issue.26
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
50
-
-
51149116051
-
CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS
-
Hodi FS, Oble DA, Drappatz J et al. CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS. Nat. Clin. Pract. Oncol. 5(9), 557-561 (2008).
-
(2008)
Nat. Clin. Pract. Oncol
, vol.5
, Issue.9
, pp. 557-561
-
-
Hodi, F.S.1
Oble, D.A.2
Drappatz, J.3
-
51
-
-
36748999428
-
Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade
-
22 Pt 1
-
Downey SG, Klapper JA, Smith FO et al. Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade. Clin. Cancer Res. 13(22 Pt 1), 6681-6688 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 6681-6688
-
-
Downey, S.G.1
Klapper, J.A.2
Smith, F.O.3
-
52
-
-
77952238391
-
Complete regression of a previously untreated melanoma brain metastasis with ipilimumab
-
Schartz NE, Farges C, Madelaine I et al. Complete regression of a previously untreated melanoma brain metastasis with ipilimumab. Melanoma Res. 20(3), 247-250 (2010).
-
(2010)
Melanoma Res
, vol.20
, Issue.3
, pp. 247-250
-
-
Schartz, N.E.1
Farges, C.2
Madelaine, I.3
-
53
-
-
38649094865
-
The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: Patient cases
-
Saenger YM, Wolchok JD. The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: Patient cases. Cancer Immun. 8, 1 (2008).
-
(2008)
Cancer Immun
, vol.8
, pp. 1
-
-
Saenger, Y.M.1
Wolchok, J.D.2
-
54
-
-
77957587190
-
Phase II trial of ipilimumab monotherapy in melanoma patients with brain metastases
-
Abstract
-
Lawrence DP, Hamid HO, Mcdermott DF et al. Phase II trial of ipilimumab monotherapy in melanoma patients with brain metastases. J. Clin. Oncol. 28(15 Suppl.), Abstract 8523 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.SUPPL.
, pp. 8523
-
-
Lawrence, D.P.1
Hamid, H.O.2
Mcdermott, D.F.3
-
55
-
-
0036200194
-
Protein kinase B (Akt) regulation and function in T lymphocytes
-
Cantrell D. Protein kinase B (Akt) regulation and function in T lymphocytes. Semin. Immunol. 14(1), 19-26 (2002).
-
(2002)
Semin. Immunol
, vol.14
, Issue.1
, pp. 19-26
-
-
Cantrell, D.1
-
56
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192(7), 1027-1034 (2000).
-
(2000)
J. Exp. Med
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
57
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc. Natl. Acad. Sci. USA 99(19), 12293-12297 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.19
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
58
-
-
77954899030
-
Phase I study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I et al. Phase I study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 28(19), 3167-3175 (2010).
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.19
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
59
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366(26), 2443-2454 (2012).
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
60
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R, Rotem-Yehudar R, Slama G et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res. 14(10), 3044-3051 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
Rotem-Yehudar, R.2
Slama, G.3
-
62
-
-
55949113750
-
Phase I study of BMS-663513, a fully human anti-CD137 against monoclonal antibody, in patients (pts) with advanced cancer
-
Abstract 3007 2008
-
Sznol M, Hodi FS, Margolin K. Phase I study of BMS-663513, a fully human anti-CD137 against monoclonal antibody, in patients (pts) with advanced cancer. J. Clin. Oncol. 2008(26), Abstract 3007 (2008).
-
J. Clin. Oncol
, vol.2008
, Issue.26
-
-
Sznol, M.1
Hodi, F.S.2
Margolin, K.3
-
64
-
-
68949156442
-
Betting on immunotherapy for melanoma
-
Sznol M. Betting on immunotherapy for melanoma. Curr. Oncol. Rep. 11(5), 397-404 (2009).
-
(2009)
Curr. Oncol. Rep
, vol.11
, Issue.5
, pp. 397-404
-
-
Sznol, M.1
-
65
-
-
0344440962
-
LAG-3: A regulator of T-cell and DC responses and its use in therapeutic vaccination
-
Triebel F. LAG-3: A regulator of T-cell and DC responses and its use in therapeutic vaccination. Trends Immunol. 24(12), 619-622 (2003).
-
(2003)
Trends Immunol
, vol.24
, Issue.12
, pp. 619-622
-
-
Triebel, F.1
-
66
-
-
36048963838
-
LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems
-
Grosso JF, Kelleher CC, Harris TJ et al. LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems. J. Clin. Invest. 117(11), 3383-3392 (2007).
-
(2007)
J. Clin. Invest
, vol.117
, Issue.11
, pp. 3383-3392
-
-
Grosso, J.F.1
Kelleher, C.C.2
Harris, T.J.3
-
67
-
-
79851509964
-
The discovery of furo [2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors
-
Buckmelter AJ, Ren L, Laird ER et al. The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors. Bioorg. Med. Chem. Lett. 21(4), 1248-1252 (2011).
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, Issue.4
, pp. 1248-1252
-
-
Buckmelter, A.J.1
Ren, L.2
Laird, E.R.3
-
68
-
-
0034667593
-
Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
-
Pt 2
-
Kolch W. Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem. J. 351(Pt 2), 289-305 (2000).
-
(2000)
Biochem. J.
, vol.351
, pp. 289-305
-
-
Kolch, W.1
-
70
-
-
84858752302
-
An open-label pilot study of vermurafenib in previously treated metastatic melanoma patients with brain metastases
-
Abstract 8548
-
Dummer R, Rinderknecht J, Goldinger SM et al. An open-label pilot study of vermurafenib in previously treated metastatic melanoma patients with brain metastases. J. Clin. Oncol. 29(15 Suppl.), Abstract 8548 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.SUPPL.
-
-
Dummer, R.1
Rinderknecht, J.2
Goldinger, S.M.3
-
71
-
-
84855179546
-
Vemurafenib for melanoma metastases to the brain
-
Rochet NM, Kottschade LA, Markovic SN. Vemurafenib for melanoma metastases to the brain. N. Engl. J. Med. 365(25), 2439-2441 (2011).
-
(2011)
N. Engl. J. Med
, vol.365
, Issue.25
, pp. 2439-2441
-
-
Rochet, N.M.1
Kottschade, L.A.2
Markovic, S.N.3
-
72
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A Phase 1 dose-escalation trial
-
Falchook GS, Long GV, Kurzrock R et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A Phase 1 dose-escalation trial. Lancet 379(9829), 1893-1901 (2012).
-
(2012)
Lancet
, vol.379
, Issue.9829
, pp. 1893-1901
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
-
73
-
-
77957350123
-
Phase I/II study of GSK2118436, a selective inhibitor of oncogenic mutant BRAF kinase, in patients with metastatic melanoma and other soild tumors
-
Abstract 8503
-
Kefford RF, Arkenau H, Brown MP. Phase I/II study of GSK2118436, a selective inhibitor of oncogenic mutant BRAF kinase, in patients with metastatic melanoma and other soild tumors. J. Clin. Oncol. 28(15 Suppl.), Abstract 8503 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.SUPPL.
-
-
Kefford, R.F.1
Arkenau, H.2
Brown, M.P.3
-
74
-
-
84855460517
-
BRAF inhibitors for the treatment of metastatic melanoma: Clinical trials and mechanisms of resistance
-
Alcalá AM, Flaherty KT. BRAF inhibitors for the treatment of metastatic melanoma: Clinical trials and mechanisms of resistance. Clin. Cancer Res. 18(1), 33-39 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.1
, pp. 33-39
-
-
Alcalá, A.M.1
Flaherty, K.T.2
-
75
-
-
68949106943
-
A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients (pts) with advanced solid tumors
-
Abstract 3513
-
Schwartz GK, Robertson S, Shen A. A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients (pts) with advanced solid tumors. J. Clin. Oncol. 27(15 Suppl.), Abstract 3513 (2009).
-
(2009)
J. Clin. Oncol
, vol.27
, Issue.SUPPL.
-
-
Schwartz, G.K.1
Robertson, S.2
Shen, A.3
|