Tgf-β1 Inhibits Cftr Biogenesis and Prevents Functional Rescue of ΔF508-Cftr in Primary Differentiated Human Bronchial Epithelial Cells

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Snodgrass, Steven M ^a,c   Cihil, Kristine M ^b   Cornuet, Pamela K ^b   Myerburg, Michael M ^b   Swiatecka Urban, Agnieszka ^a,b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE GREENVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; BIOGENESIS; BIOTINYLATION; BRONCHUS; CELL DIFFERENTIATION; CONTROLLED STUDY; CYSTIC FIBROSIS; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HOMOZYGOSITY; HUMAN; HUMAN CELL; LUNG FUNCTION; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; BRONCHI; CELL DIFFERENTIATION; CELL MEMBRANE; CELLS, CULTURED; CHLORIDES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; MUTATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84877346547     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063167     Document Type: Article

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