Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation

Experimental Cell Research

Volumn 313, Issue 12, 2007, Pages 2695-2702

  Skowron zwarg, Marie ^a   Boland, Sonja ^a   Caruso, Nathalie ^a   Coraux, Christelle ^b   Marano, Francelyne ^a   Tournier, Frédéric ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL MAISON BLANCHE   (France)

Author keywords

AQP5; CFTR; Human nasal epithelial cells; IL 13; Mucociliary differentiation; Primary cell culture

Indexed keywords

AQUAPORIN 5; INTERLEUKIN 13; ION CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CELL DIFFERENTIATION; CELL DISRUPTION; CELL REGENERATION; CILIATED EPITHELIUM; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HYDRATION; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; IN SITU HYBRIDIZATION; MUCUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS REGULATION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 34347262057     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.02.035     Document Type: Article

References (27)

1. Grünig G., Warnock M., Wakil A.E., Venkayya R., Brombacher F., Rennick D.M., Sheppard D., Mohrs M., Donaldson D.D., Locksley R.M., and Corry D.B. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 282 (1998) 2261-2263
2. Lee J.H., Kaminski N., Dolganov G., Grünig G., Koth L., Solomon C., Erle D.J., and Sheppard D. Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types. Am. J. Respir. Cell Mol. Biol. 25 (2001) 474-485
3. Matsukura S., Stellato C., Georas S.N., Casolaro V., Plitt J.R., Miura K., Kurosawa S., Schindler U., and Schleimer R.P. Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. Am. J. Respir. Cell Mol. Biol. 24 (2001) 755-761
4. Striz I., Mio T., Adachi Y., Robbins R.A., Romberger D.J., and Rennard S.I. IL-4 and IL-13 stimulate human bronchial epithelial cells to release IL-8. Inflammation 23 (1999) 545-555
5. Wen F.Q., Kohyama T., Liu X., Zhu Y.K., Wang H., Kim H.J., Kobayashi T., Abe S., Spurzem J.R., and Rennard S.I. Interleukin-4-and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma. Am. J. Respir. Cell Mol. Biol. 26 (2002) 484-490
6. Laoukili J., Perret E., Willems T., Minty A., Parthoens E., Houcine O., Coste A., Jorissen M., Marano F., Caput D., and Tournier F. IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells. J. Clin. Invest. 108 (2001) 1817-1824
7. Moyer B.D., Denton J., Karlson K.H., Reynolds D., Wang S., Mickle J.E., Milewski M., Cutting G.R., Guggino W.B., Li M., and Stanton B.A. A PDZ-interacting domain in CFTR is an apical membrane polarization signal. J. Clin. Invest. 104 (1999) 1353-1361
8. Puchelle E., Gaillard D., Ploton D., Hinnrasky J., Fuchey C., Boutterin M.C., Jacquot J., Dreyer D., Pavirani A., and Dalemans W. Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium. Am. J. Respir. Cell Mol. Biol. 7 (1992) 485-491
9. Cheng S.H., Gregory R.J., Marshall J., Paul S., Souza D.W., White G.A., O'Riordan C.R., and Smith A.E. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 63 (1990) 827-834
10. Kreda S.M., Gynn M.C., Fenstermacher D.A., Boucher R.C., and Gabriel S.E. Expression and localisation of epithelial aquaporins in the adult human lung. Am. J. Respir. Cell Mol. Biol. 24 (2001) 224-234
11. Danahay H., Atherton H., Jones G., Bridges R.J., and Poll C.T. Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells. Am. J. Physiol., Lung Cell. Mol. Physiol. 282 (2000) L226-L236
12. Whitcutt M.J., Adler K.B., and Wu R. A biphasic chamber system for maintaining polarity of differentiation of cultured respiratory tract epithelial cells. In Vitro Cell. Dev. Biol. 24 (1988) 420-428
13. Million K., Tournier F., Houcine O., Ancian P., and Reichert F; Marano U. Effects of retinoic acid receptor-selective agonists on human nasal epithelial cell differentiation. Am. J. Respir. Cell Mol. Biol. 25 (2001) 744-750
14. Louvard D., Reggio H., and Warren G. Antibodies to the Golgi complex and the rough endoplasmic reticulum. J. Cell Biol. 92 (1982) 92-107
15. Schreiber R., Nitschke R., Greger R., and Kunzelmann K. The cystic fibrosis transmembrane conductance regulator activates aquaporin 3 in airway epithelial cells. J. Biol. Chem. 274 (1999) 11811-11816
16. Booth B.W., Adler K.B., Bonner J.C., Tournier F., and Martin L.D. Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha. Am. J. Respir. Cell Mol. Biol. 25 (2001) 739-743
17. Denning G.M., Ostedgaard L.S., and Welsh M.J. Abnormal localization of cystic fibrosis transmembrane conductance regulator in primary cultures of cystic fibrosis airway epithelia. J. Cell Biol. 118 (1992) 551-559
18. Milewski M.I., Mickle J.E., Forrest J.K., Stafford D.M., Moyer B.D., Cheng J., Guggino W.B., Stanton B.A., and Cutting G. A PDZ-binding motif is essential but not sufficient to localize the C terminus of CFTR to the apical membrane. J. Cell. Sci. 114 (2000) 719-726
19. Short D.B., Trotter K.W., Reczek D., Kreda S.M., Bretscher A., Boucher R.C., Stutts M.J., and Milgram S.L. An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. J. Biol. Chem. 273 (1998) 19797-19801
20. Gabriel S.E., Clarke L.L., Boucher R.C., and Stutts M.J. CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship. Nature 363 (1993) 263-268
21. Stutts M.J., Canessa C.M., Olsen J.C., Hamrick M., Cohn J.A., Rossier B.C., and Boucher R.C. CFTR as a cAMP-dependent regulator of sodium channels. Science 269 (1995) 847-850
22. Towne J.E., Krane C.M., Bachurski C.J., and Menon A.G. Tumor necrosis factor-alpha inhibits aquaporin 5 expression in mouse lung epithelial cells. J. Biol. Chem. 276 (2001) 18657-18664
23. Yang F., Kawedia F.J.D., and Menon A.G. Cyclic AMP regulates aquaporin 5 expression at both transcriptional and post-transcriptional levels through a protein kinase A pathway. J. Biol. Chem. 278 (2003) 32173-32180
24. Ma T., Fukuda N., Song Y., Matthay M.A., and Verkman A.S. Lung fluid transport in aquaporin-5 knockout mice. J. Clin. Invest. 105 (2000) 93-100
25. Tsubota K., Hirai S., King L.S., Agre P., and Ishida N. Defective cellular trafficking of lacrimal gland aquaporin-5 in Sjogren's syndrome. Lancet 357 (2001) 688-689
26. Zuhdi Alimam M., Piazza F.M., Selby D.M., Letwin N., Huang L., and Rose M.C. Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways. Am. J. Respir. Cell Mol. Biol. 22 (2000) 253-260
27. Tyner J.W., Kim E.Y., Ide K., Pelletier M.R., Roswit W.T., Morton J.D., Battaile J.T., Paatel A.C., Patterson G.A., Castro M., Spoor M.S., You Y., Brody S.L., and Holtzman M.J. Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals. J. Clin. Invest. 116 (2006) 309-321