Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis

Journal of Cell Biology

Volumn 187, Issue 1, 2009, Pages 15-23

  Smith, Kevin D ^a,b   Fu, Michael A ^a,b   Brown, Eric J ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; HISTONE H2AX; NUCLEOTIDE; PROTEIN; SINGLE STRANDED DNA; TIM PROTEIN; TIPIN PROTEIN; UNCLASSIFIED DRUG; ATR PROTEIN, MOUSE; CARRIER PROTEIN; CELL CYCLE PROTEIN; NUCLEAR PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TIMELESS PROTEIN, MOUSE; TIPIN PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; DNA REPLICATION; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL LINE; CELL STRAIN 3T3; CHEMISTRY; GENE VECTOR; GENETICS; IMMUNOHISTOCHEMISTRY; LENTIVIRINAE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE; DNA REPLICATION; DNA, SINGLE-STRANDED; ENZYME ACTIVATION; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LENTIVIRUS; MICE; MODELS, GENETIC; NIH 3T3 CELLS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING;

EID: 70449707748     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200905006     Document Type: Article

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