-
1
-
-
0346186100
-
A key role for TRPM7 channels in anoxic neuronal death
-
Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell 115: 863-877, 2003.
-
(2003)
Cell
, vol.115
, pp. 863-877
-
-
Aarts, M.1
Iihara, K.2
Wei, W.L.3
Xiong, Z.G.4
Arundine, M.5
Cerwinski, W.6
Macdonald, J.F.7
Tymianski, M.8
-
2
-
-
78650679916
-
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracel-lular calcium levels by selected L-type calcium channel blockers
-
An Haack K, Narayan SB, Li H, Warnock A, Tan L, Bennett MJ. Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracel-lular calcium levels by selected L-type calcium channel blockers. Biochim Biophys Acta 1810: 186-191, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1810
, pp. 186-191
-
-
An Haack, K.1
Narayan, S.B.2
Li, H.3
Warnock, A.4
Tan, L.5
Bennett, M.J.6
-
3
-
-
77649274710
-
Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organo-typic hippocampal culture
-
Bai JZ, Lipski J. Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organo-typic hippocampal culture. Neurotoxicology 31: 204-214, 2010.
-
(2010)
Neurotoxicology
, vol.31
, pp. 204-214
-
-
Bai, J.Z.1
Lipski, J.2
-
5
-
-
33846264865
-
TRP proteins and cancer
-
Bodding M. TRP proteins and cancer. Cell Signal 19: 617-624, 2007.
-
(2007)
Cell Signal
, vol.19
, pp. 617-624
-
-
Bodding, M.1
-
6
-
-
79551542888
-
PTEN level in tumor suppres-sion: How much is too little?
-
Carracedo A, Alimonti A, Pandolfi PP. PTEN level in tumor suppres-sion: how much is too little? Cancer Res 71: 629-633, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 629-633
-
-
Carracedo, A.1
Alimonti, A.2
Pandolfi, P.P.3
-
7
-
-
0031017844
-
Modula-tion of calcium channels in human erythroblasts by erythropoietin
-
Cheung JY, Zhang XQ, Bokvist K, Tillotson DL, Miller BA. Modula-tion of calcium channels in human erythroblasts by erythropoietin. Blood 89: 92-100, 1997.
-
(1997)
Blood
, vol.89
, pp. 92-100
-
-
Cheung, J.Y.1
Zhang, X.Q.2
Bokvist, K.3
Tillotson, D.L.4
Miller, B.A.5
-
8
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham DE. TRP channels as cellular sensors. Nature 426: 517-524, 2003.
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
9
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and prolif-eration
-
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and prolif-eration. Cell Metab 7: 11-20, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
10
-
-
0033709579
-
Patterns of melastatin mRNA expres-sion in melanocytic tumors
-
Deeds J, Cronin F, Duncan LM. Patterns of melastatin mRNA expres-sion in melanocytic tumors. Hum Pathol 31: 1346-1356, 2000.
-
(2000)
Hum Pathol
, vol.31
, pp. 1346-1356
-
-
Deeds, J.1
Cronin, F.2
Duncan, L.M.3
-
11
-
-
83855165656
-
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation
-
Di A, Gao XP, Qian F, Kawamura T, Han J, Hecquet C, Ye RD, Vogel SM, Malik AB. The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nat Immunol 13: 29-35, 2012.
-
(2012)
Nat Immunol
, vol.13
, pp. 29-35
-
-
Di, A.1
Gao, X.P.2
Qian, F.3
Kawamura, T.4
Han, J.5
Hecquet, C.6
Ye, R.D.7
Vogel, S.M.8
Malik, A.B.9
-
12
-
-
77949756203
-
TRP channels and the control of vascular function
-
Di A, Malik AB. TRP channels and the control of vascular function. Curr Opin Pharmacol 10: 127-132, 2010.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 127-132
-
-
Di, A.1
Malik, A.B.2
-
13
-
-
66349113192
-
Intracellular calcium activates TRPM2 and its alternative spliced isoforms
-
Du J, Xie J, Yue L. Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc Natl Acad Sci USA 106: 7239-7244, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7239-7244
-
-
Du, J.1
Xie, J.2
Yue, L.3
-
15
-
-
0032054272
-
Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis
-
Duncan LM, Deeds J, Hunter J, Shao J, Holmgren LM, Woolf EA, Tepper RI, Shyjan AW. Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res 58: 1515-1520, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 1515-1520
-
-
Duncan, L.M.1
Deeds, J.2
Hunter, J.3
Shao, J.4
Holmgren, L.M.5
Woolf, E.A.6
Tepper, R.I.7
Shyjan, A.W.8
-
16
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM, Thompson CB. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64: 3892-3899, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
Zhuang, H.7
Cinalli, R.M.8
Alavi, A.9
Rudin, C.M.10
Thompson, C.B.11
-
17
-
-
0034627233
-
Expression and up-regulation of alternatively spliced transcripts of melastatin, a melanoma metastasis-related gene, in human melanoma cells
-
Fang D, Setaluri V. Expression and up-regulation of alternatively spliced transcripts of melastatin, a melanoma metastasis-related gene, in human melanoma cells. Biochem Biophys Res Commun 279: 53-61, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 53-61
-
-
Fang, D.1
Setaluri, V.2
-
18
-
-
27644507847
-
Amyloid β-pep-tide(1-42)-and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures
-
Fonfria E, Marshall IC, Boyfield I, Skaper SD, Hughes JP, Owen DE, Zhang W, Miller BA, Benham CD, McNulty S. Amyloid β-pep-tide(1-42)-and hydrogen peroxide-induced toxicity are mediated by TRPM2 in rat primary striatal cultures. J Neurochem 95: 715-723, 2005.
-
(2005)
J Neurochem
, vol.95
, pp. 715-723
-
-
Fonfria, E.1
Marshall, I.C.2
Boyfield, I.3
Skaper, S.D.4
Hughes, J.P.5
Owen, D.E.6
Zhang, W.7
Miller, B.A.8
Benham, C.D.9
McNulty, S.10
-
19
-
-
33646343224
-
Activation of T cell calcium influx by the second messenger ADP-ribose
-
Gasser A, Glassmeier G, Fliegert R, Langhorst MF, Meinke S, Hein D, Kruger S, Weber K, Heiner I, Oppenheimer N, Schwarz JR, Guse AH. Activation of T cell calcium influx by the second messenger ADP-ribose. J Biol Chem 281: 2489-2496, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2489-2496
-
-
Gasser, A.1
Glassmeier, G.2
Fliegert, R.3
Langhorst, M.F.4
Meinke, S.5
Hein, D.6
Kruger, S.7
Weber, K.8
Heiner, I.9
Oppenheimer, N.10
Schwarz, J.R.11
Guse, A.H.12
-
20
-
-
79954613077
-
CREB is a novel nuclear target of PTEN phosphatase
-
Gu T, Zhang Z, Wang J, Guo J, Shen WH, Yin Y. CREB is a novel nuclear target of PTEN phosphatase. Cancer Res 71: 2821-2825, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 2821-2825
-
-
Gu, T.1
Zhang, Z.2
Wang, J.3
Guo, J.4
Shen, W.H.5
Yin, Y.6
-
21
-
-
70349253981
-
Evidence that TRPM7 is required for breast cancer cell proliferation
-
Guilbert A, Gautier M, Dhennin-Duthille I, Haren N, Sevestre H, Ouadid-Ahidouch H. Evidence that TRPM7 is required for breast cancer cell proliferation. Am J Physiol Cell Physiol 297: C493-C502, 2009.
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Guilbert, A.1
Gautier, M.2
Dhennin-Duthille, I.3
Haren, N.4
Sevestre, H.5
Ouadid-Ahidouch, H.6
-
22
-
-
33846331650
-
Oxidative stress and cancer: Have we moved forward?
-
Halliwell B. Oxidative stress and cancer: have we moved forward? Biochem J 401: 1-11, 2007.
-
(2007)
Biochem J
, vol.401
, pp. 1-11
-
-
Halliwell, B.1
-
23
-
-
18244391511
-
2+ -permeable channel activated by changes in redox status confers susceptibility to cell death
-
2+ -permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell 9: 163-173, 2002.
-
(2002)
Mol Cell
, vol.9
, pp. 163-173
-
-
Hara, Y.1
Wakamori, M.2
Ishii, M.3
Maeno, E.4
Nishida, M.5
Yoshida, T.6
Yamada, H.7
Shimizu, S.8
Mori, E.9
Kudoh, J.10
Shimizu, N.11
Kurose, H.12
Okada, Y.13
Imoto, K.14
Mori, Y.15
-
24
-
-
64849110665
-
2-activated TRPM2 calcium chan-nel in oxidant-induced endothelial injury
-
Hecquet CM, Malik AB. Role of H2O2-activated TRPM2 calcium chan-nel in oxidant-induced endothelial injury. Thromb Haemost 101: 619-625, 2009.
-
(2009)
Thromb Haemost
, vol.101
, pp. 619-625
-
-
Hecquet, C.M.1
Malik, A.B.2
-
25
-
-
11244343900
-
Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole
-
Hill K, McNulty S, Randall AD. Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole. Naunyn Schmiedebergs Arch Pharmacol 370: 227-237, 2004.
-
(2004)
Naunyn Schmiedebergs Arch Pharmacol
, vol.370
, pp. 227-237
-
-
Hill, K.1
McNulty, S.2
Randall, A.D.3
-
26
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang H, Tindall DJ. Dynamic FoxO transcription factors. J Cell Sci 120: 2479-2487, 2007.
-
(2007)
J Cell Sci
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
27
-
-
0028982744
-
2 in vitro
-
Hyslop PA, Zhang Z, Pearson DV, Phebus LA. Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfu-sion in the rat: correlation with the cytotoxic potential of H2O2 in vitro. Brain Res 671: 181-186, 1995.
-
(1995)
Brain Res
, vol.671
, pp. 181-186
-
-
Hyslop, P.A.1
Zhang, Z.2
Pearson, D.V.3
Phebus, L.A.4
-
28
-
-
27344448624
-
Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression
-
Iiyama M, Kakihana K, Kurosu T, Miura O. Reactive oxygen species generated by hematopoietic cytokines play roles in activation of receptor-mediated signaling and in cell cycle progression. Cell Signal 18: 174-182, 2006.
-
(2006)
Cell Signal
, vol.18
, pp. 174-182
-
-
Iiyama, M.1
Kakihana, K.2
Kurosu, T.3
Miura, O.4
-
29
-
-
33646788796
-
A critical role of TRPM2 in neuronal cell death by hydrogen peroxide
-
Kaneko S, Kawakami S, Hara Y, Wakamori M, Itoh E, Minami T, Takada Y, Kume T, Katsuki H, Mori Y, Akaike A. A critical role of TRPM2 in neuronal cell death by hydrogen peroxide. J Pharm Sci 101: 66-76, 2006.
-
(2006)
J Pharm Sci
, vol.101
, pp. 66-76
-
-
Kaneko, S.1
Kawakami, S.2
Hara, Y.3
Wakamori, M.4
Itoh, E.5
Minami, T.6
Takada, Y.7
Kume, T.8
Katsuki, H.9
Mori, Y.10
Akaike, A.11
-
30
-
-
84860179123
-
Redox signal-mediated sensitization of tran-sient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions
-
Kashio M, Sokabe T, Shintaku K, Uematsu T, Fukuta N, Kobayashi N, Mori Y, Tominaga M. Redox signal-mediated sensitization of tran-sient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions. Proc Natl Acad Sci USA 109: 6745-6750, 2012.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 6745-6750
-
-
Kashio, M.1
Sokabe, T.2
Shintaku, K.3
Uematsu, T.4
Fukuta, N.5
Kobayashi, N.6
Mori, Y.7
Tominaga, M.8
-
31
-
-
15944417442
-
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
-
Kolisek M, Beck A, Fleig A, Penner R. Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Mol Cell 18: 61-69, 2005.
-
(2005)
Mol Cell
, vol.18
, pp. 61-69
-
-
Kolisek, M.1
Beck, A.2
Fleig, A.3
Penner, R.4
-
32
-
-
0037136563
-
Forkhead tran-scription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM. Forkhead tran-scription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419: 316-321, 2002.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
33
-
-
26444439972
-
TRPM2: A calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose
-
Kuhn FJ, Heiner I, Luckhoff A. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose. Pflügers Arch 451: 212-219, 2005.
-
(2005)
Pflügers Arch
, vol.451
, pp. 212-219
-
-
Kuhn, F.J.1
Heiner, I.2
Luckhoff, A.3
-
34
-
-
4444277253
-
Oxidative stress-induced death in the nervous system: Cell cycle dependent or independent?
-
Langley B, Ratan RR. Oxidative stress-induced death in the nervous system: cell cycle dependent or independent? J Neurosci Res 77: 621-629, 2004.
-
(2004)
J Neurosci Res
, vol.77
, pp. 621-629
-
-
Langley, B.1
Ratan, R.R.2
-
36
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
Levine AJ, Puzio-Kuter AM. The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science 330: 1340-1344, 2010.
-
(2010)
Science
, vol.330
, pp. 1340-1344
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
37
-
-
33845967865
-
Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats
-
Li M, Chiu JF, Mossman BT, Fukagawa NK. Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats. J Biol Chem 281: 40429-40439, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 40429-40439
-
-
Li, M.1
Chiu, J.F.2
Mossman, B.T.3
Fukagawa, N.K.4
-
38
-
-
80054087824
-
Mitochondrial ROS generation for regulation of autophagic pathways in cancer
-
Li ZY, Yang Y, Ming M, Liu B. Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem Biophys Res Com-mun 414: 5-8, 2011.
-
(2011)
Biochem Biophys Res Com-mun
, vol.414
, pp. 5-8
-
-
Li, Z.Y.1
Yang, Y.2
Ming, M.3
Liu, B.4
-
39
-
-
33747774141
-
Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin
-
Maraldi T, Rugolo M, Fiorentini D, Landi L, Hakim G. Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin. Cell Calcium 40: 373-381, 2006.
-
(2006)
Cell Calcium
, vol.40
, pp. 373-381
-
-
Maraldi, T.1
Rugolo, M.2
Fiorentini, D.3
Landi, L.4
Hakim, G.5
-
40
-
-
34547699517
-
Foxo3 is required for the regulation of oxidative stress in erythropoiesis
-
Marinkovic D, Zhang X, Yalcin S, Luciano JP, Brugnara C, Huber T, Ghaffari S. Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest 117: 2133-2144, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 2133-2144
-
-
Marinkovic, D.1
Zhang, X.2
Yalcin, S.3
Luciano, J.P.4
Brugnara, C.5
Huber, T.6
Ghaffari, S.7
-
42
-
-
0033575229
-
Identification of the erythropoi-etin receptor domain required for calcium channel activation
-
Miller BA, Barber DL, Bell LL, Beattie BK, Zhang MY, Neel BG, Yoakim M, Rothblum LI, Cheung JY. Identification of the erythropoi-etin receptor domain required for calcium channel activation. J Biol Chem 274: 20465-20472, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 20465-20472
-
-
Miller, B.A.1
Barber, D.L.2
Bell, L.L.3
Beattie, B.K.4
Zhang, M.Y.5
Neel, B.G.6
Yoakim, M.7
Rothblum, L.I.8
Cheung, J.Y.9
-
43
-
-
79959794425
-
TRP channels as mediators of oxidative stress
-
Miller BA, Zhang W. TRP channels as mediators of oxidative stress. Adv Exp Med Biol 704: 531-544, 2011.
-
(2011)
Adv Exp Med Biol
, vol.704
, pp. 531-544
-
-
Miller, B.A.1
Zhang, W.2
-
44
-
-
33644875032
-
The TRP superfamily of cation channels
-
Montell C. The TRP superfamily of cation channels. Sci STKE 2005: re3, 2005.
-
(2005)
Sci STKE
, vol.2005
-
-
Montell, C.1
-
45
-
-
77955569436
-
Transient receptor potential channelopathies
-
Nilius B, Owsianik G. Transient receptor potential channelopathies. Pflügers Arch 460: 437-450, 2010.
-
(2010)
Pflügers Arch
, vol.460
, pp. 437-450
-
-
Nilius, B.1
Owsianik, G.2
-
46
-
-
56849118516
-
Akt determines replicative senescence and oxidative or onco-genic premature senescence and sensitizes cells to oxidative apoptosis
-
Nogueira V, Park Y, Chen CC, Xu PZ, Chen ML, Tonic I, Unterman T, Hay N. Akt determines replicative senescence and oxidative or onco-genic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14: 458-470, 2008.
-
(2008)
Cancer Cell
, vol.14
, pp. 458-470
-
-
Nogueira, V.1
Park, Y.2
Chen, C.C.3
Xu, P.Z.4
Chen, M.L.5
Tonic, I.6
Unterman, T.7
Hay, N.8
-
47
-
-
55549140796
-
Identification of novel sense and antisense transcription at the TRPM2 locus in cancer
-
Orfanelli U, Wenke AK, Doglioni C, Russo V, Bosserhoff AK, Lavor-gna G. Identification of novel sense and antisense transcription at the TRPM2 locus in cancer. Cell Res 18: 1128-1140, 2008.
-
(2008)
Cell Res
, vol.18
, pp. 1128-1140
-
-
Orfanelli, U.1
Wenke, A.K.2
Doglioni, C.3
Russo, V.4
Bosserhoff, A.K.5
Lavor-Gna, G.6
-
48
-
-
1342342989
-
Human cancer, PTEN and the PI-3 kinase pathway
-
Parsons R. Human cancer, PTEN and the PI-3 kinase pathway. Semin Cell Dev Biol 15: 171-176, 2004.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 171-176
-
-
Parsons, R.1
-
49
-
-
78649476090
-
Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene
-
Pellicano F, Thomson RE, Inman GJ, Iwata T. Regulation of cell proliferation and apoptosis in neuroblastoma cells by ccp1, a FGF2 downstream gene. BMC Cancer 10: 657, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 657
-
-
Pellicano, F.1
Thomson, R.E.2
Inman, G.J.3
Iwata, T.4
-
50
-
-
20044388114
-
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels
-
Perraud AL, Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels. J Biol Chem 280: 6138-6148, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 6138-6148
-
-
Perraud, A.L.1
Takanishi, C.L.2
Shen, B.3
Kang, S.4
Smith, M.K.5
Schmitz, C.6
Knowles, H.M.7
Ferraris, D.8
Li, W.9
Zhang, J.10
Stoddard, B.L.11
Scharenberg, A.M.12
-
51
-
-
0033958493
-
Identification and charac-terization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression
-
Prawitt D, Enklaar T, Klemm G, Gartner B, Spangenberg C, Win-terpacht A, Higgins M, Pelletier J, Zabel B. Identification and charac-terization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression. Hum Mol Genet 9: 203-216, 2000.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 203-216
-
-
Prawitt, D.1
Enklaar, T.2
Klemm, G.3
Gartner, B.4
Spangenberg, C.5
Win-Terpacht, A.6
Higgins, M.7
Pelletier, J.8
Zabel, B.9
-
52
-
-
0033514509
-
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway
-
Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci USA 96: 2110-2115, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2110-2115
-
-
Ramaswamy, S.1
Nakamura, N.2
Vazquez, F.3
Batt, D.B.4
Perera, S.5
Roberts, T.M.6
Sellers, W.R.7
-
53
-
-
84857116578
-
Reactive oxygen species (ROS) homeo-stasis and redox regulation in cellular signaling
-
Ray PD, Huang BW, Tsuji Y. Reactive oxygen species (ROS) homeo-stasis and redox regulation in cellular signaling. Cell Signal 24: 981-990, 2012.
-
(2012)
Cell Signal
, vol.24
, pp. 981-990
-
-
Ray, P.D.1
Huang, B.W.2
Tsuji, Y.3
-
54
-
-
77949463188
-
Vertebrate vision: TRP channels in the spotlight
-
Ribelayga C. Vertebrate vision: TRP channels in the spotlight. Curr Biol 20: R278-280, 2010.
-
(2010)
Curr Biol
, vol.20
-
-
Ribelayga, C.1
-
55
-
-
60549111398
-
Is Akt the "Warburg kinase"? Akt-energy metabolism interactions and oncogenesis
-
Robey RB, Hay N. Is Akt the "Warburg kinase"? Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol 19: 25-31, 2009.
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 25-31
-
-
Robey, R.B.1
Hay, N.2
-
56
-
-
0025799991
-
An improved colorimetric assay for cell proliferation and viability utilizing the tetrazo-lium salt XTT
-
Roehm NW, Rodgers GH, Hatfield SM, Glasebrook AL. An improved colorimetric assay for cell proliferation and viability utilizing the tetrazo-lium salt XTT. J Immunol Methods 142: 257-265, 1991.
-
(1991)
J Immunol Methods
, vol.142
, pp. 257-265
-
-
Roehm, N.W.1
Rodgers, G.H.2
Hatfield, S.M.3
Glasebrook, A.L.4
-
58
-
-
0035902767
-
2+ influx system mediated by LTRPC2
-
2+ influx system mediated by LTRPC2. Science 293: 1327-1330, 2001.
-
(2001)
Science
, vol.293
, pp. 1327-1330
-
-
Sano, Y.1
Inamura, K.2
Miyake, A.3
Mochizuki, S.4
Yokoi, H.5
Matsushime, H.6
Furuichi, K.7
-
60
-
-
11144279346
-
The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phospho-inositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway
-
Seo JH, Ahn Y, Lee SR, Yeol Yeo C, Chung Hur K. The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phospho-inositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway. Mol Biol Cell 16: 348-357, 2005.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 348-357
-
-
Seo, J.H.1
Ahn, Y.2
Lee, S.R.3
Yeol Yeo, C.4
Chung Hur, K.5
-
61
-
-
80052338518
-
TRP channels in cell survival and cell death in normal and transformed cells
-
Shapovalov G, Lehen'kyi V, Skryma R, Prevarskaya N. TRP channels in cell survival and cell death in normal and transformed cells. Cell Calcium 50: 295-302, 2011.
-
(2011)
Cell Calcium
, vol.50
, pp. 295-302
-
-
Shapovalov, G.1
Lehen'Kyi, V.2
Skryma, R.3
Prevarskaya, N.4
-
62
-
-
73049085663
-
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels
-
Sharif-Naeini R, Folgering JH, Bichet D, Duprat F, Delmas P, Patel A, Honore E. Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. J Mol Cell Cardiol 48: 83-89, 2010.
-
(2010)
J Mol Cell Cardiol
, vol.48
, pp. 83-89
-
-
Sharif-Naeini, R.1
Folgering, J.H.2
Bichet, D.3
Duprat, F.4
Delmas, P.5
Patel, A.6
Honore, E.7
-
63
-
-
55849138418
-
PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability
-
Silva A, Yunes JA, Cardoso BA, Martins LR, Jotta PY, Abecasis M, Nowill AE, Leslie NR, Cardoso AA, Barata JT. PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability. J Clin Invest 118: 3762-3774, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 3762-3774
-
-
Silva, A.1
Yunes, J.A.2
Cardoso, B.A.3
Martins, L.R.4
Jotta, P.Y.5
Abecasis, M.6
Nowill, A.E.7
Leslie, N.R.8
Cardoso, A.A.9
Barata, J.T.10
-
64
-
-
77953542201
-
Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species
-
Soletti RC, del Barrio L, Daffre S, Miranda A, Borges HL, Moura-Neto V, Lopez MG, Gabilan NH. Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species. Chem Biol Interact 186: 135-143, 2010.
-
(2010)
Chem Biol Interact
, vol.186
, pp. 135-143
-
-
Soletti, R.C.1
del Barrio, L.2
Daffre, S.3
Miranda, A.4
Borges, H.L.5
Moura-Neto, V.6
Lopez, M.G.7
Gabilan, N.H.8
-
65
-
-
33746647102
-
+ diffuse large B-cell lymphoma subgroup: Development of a CD5 signature
-
+ diffuse large B-cell lymphoma subgroup: development of a CD5 signature. Cancer Sci 97: 868-874, 2006.
-
(2006)
Cancer Sci
, vol.97
, pp. 868-874
-
-
Suguro, M.1
Tagawa, H.2
Kagami, Y.3
Okamoto, M.4
Ohshima, K.5
Shiku, H.6
Morishima, Y.7
Nakamura, S.8
Seto, M.9
-
66
-
-
79953153188
-
TRPM2: A multifunctional ion channel for calcium signalling
-
Sumoza-Toledo A, Penner R. TRPM2: a multifunctional ion channel for calcium signalling. J Physiol 589: 1515-1525, 2011.
-
(2011)
J Physiol
, vol.589
, pp. 1515-1525
-
-
Sumoza-Toledo, A.1
Penner, R.2
-
67
-
-
79960709505
-
Roles of TRPM2 in oxidative stress
-
Takahashi N, Kozai D, Kobayashi R, Ebert M, Mori Y. Roles of TRPM2 in oxidative stress. Cell Calcium 50: 279-287, 2011.
-
(2011)
Cell Calcium
, vol.50
, pp. 279-287
-
-
Takahashi, N.1
Kozai, D.2
Kobayashi, R.3
Ebert, M.4
Mori, Y.5
-
68
-
-
33646543034
-
TRPM2 activation by cyclic ADP-ribose at body tem-perature is involved in insulin secretion
-
Togashi K, Hara Y, Tominaga T, Higashi T, Konishi Y, Mori Y, Tominaga M. TRPM2 activation by cyclic ADP-ribose at body tem-perature is involved in insulin secretion. EMBO J 25: 1804-1815, 2006.
-
(2006)
EMBO J
, vol.25
, pp. 1804-1815
-
-
Togashi, K.1
Hara, Y.2
Tominaga, T.3
Higashi, T.4
Konishi, Y.5
Mori, Y.6
Tominaga, M.7
-
69
-
-
33646950509
-
2+ sensor calmodulin
-
2+ sensor calmodulin. J Biol Chem 281: 9076-9085, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 9076-9085
-
-
Tong, Q.1
Zhang, W.2
Conrad, K.3
Mostoller, K.4
Cheung, J.Y.5
Peterson, B.Z.6
Miller, B.A.7
-
70
-
-
0035328671
-
Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malig-nancies and shares high homology with transient receptor potential cal-cium channel proteins
-
Tsavaler L, Shapero MH, Morkowski S, Laus R. Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malig-nancies and shares high homology with transient receptor potential cal-cium channel proteins. Cancer Res 61: 3760-3769, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3760-3769
-
-
Tsavaler, L.1
Shapero, M.H.2
Morkowski, S.3
Laus, R.4
-
71
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033, 2009.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
72
-
-
0034904776
-
Growth factors can influence cell growth and survival through effects on glucose metabolism
-
Vander Heiden MG, Plas DR, Rathmell JC, Fox CJ, Harris MH, Thompson CB. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol Cell Biol 21: 5899-5912, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5899-5912
-
-
Vander Heiden, M.G.1
Plas, D.R.2
Rathmell, J.C.3
Fox, C.J.4
Harris, M.H.5
Thompson, C.B.6
-
73
-
-
34147210988
-
Hydrogen peroxide sensing and signal-ing
-
Veal EA, Day AM, Morgan BA. Hydrogen peroxide sensing and signal-ing. Mol Cell 26: 1-14, 2007.
-
(2007)
Mol Cell
, vol.26
, pp. 1-14
-
-
Veal, E.A.1
Day, A.M.2
Morgan, B.A.3
-
75
-
-
11144338185
-
Redox active calcium ion channels and cell death
-
Waring P. Redox active calcium ion channels and cell death. Arch Biochem Biophys 434: 33-42, 2005.
-
(2005)
Arch Biochem Biophys
, vol.434
, pp. 33-42
-
-
Waring, P.1
-
76
-
-
0037189484
-
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose
-
Wehage E, Eisfeld J, Heiner I, Jungling E, Zitt C, Luckhoff A. Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose. J Biol Chem 277: 23150-23156, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 23150-23156
-
-
Wehage, E.1
Eisfeld, J.2
Heiner, I.3
Jungling, E.4
Zitt, C.5
Luckhoff, A.6
-
78
-
-
34247184208
-
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking
-
Wieman HL, Wofford JA, Rathmell JC. Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol Biol Cell 18: 1437-1446, 2007.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1437-1446
-
-
Wieman, H.L.1
Wofford, J.A.2
Rathmell, J.C.3
-
80
-
-
0035845566
-
Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform
-
Xu XZ, Moebius F, Gill DL, Montell C. Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform. Proc Natl Acad Sci USA 98: 10692-10697, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10692-10697
-
-
Xu, X.Z.1
Moebius, F.2
Gill, D.L.3
Montell, C.4
-
81
-
-
46849091975
-
2+ influx induces chemokine production in monocytes that aggravates inflam-matory neutrophil infiltration
-
2+ influx induces chemokine production in monocytes that aggravates inflam-matory neutrophil infiltration. Nat Med 14: 738-747, 2008.
-
(2008)
Nat Med
, vol.14
, pp. 738-747
-
-
Yamamoto, S.1
Shimizu, S.2
Kiyonaka, S.3
Takahashi, N.4
Wajima, T.5
Hara, Y.6
Negoro, T.7
Hiroi, T.8
Kiuchi, Y.9
Okada, T.10
Kaneko, S.11
Lange, I.12
Fleig, A.13
Penner, R.14
Nishi, M.15
Takeshima, H.16
Mori, Y.17
-
82
-
-
77955266662
-
Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels
-
Yamamoto S, Takahashi N, Mori Y. Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels. Prog Biophys Mol Biol 103: 18-27, 2010.
-
(2010)
Prog Biophys Mol Biol
, vol.103
, pp. 18-27
-
-
Yamamoto, S.1
Takahashi, N.2
Mori, Y.3
-
83
-
-
38849139580
-
ERK pro-motes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degra-dation
-
Yang JY, Zong CS, Xia W, Yamaguchi H, Ding Q, Xie X, Lang JY, Lai CC, Chang CJ, Huang WC, Huang H, Kuo HP, Lee DF, Li LY, Lien HC, Cheng X, Chang KJ, Hsiao CD, Tsai FJ, Tsai CH, Sahin AA, Muller WJ, Mills GB, Yu D, Hortobagyi GN, Hung MC. ERK pro-motes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degra-dation. Nat Cell Biol 10: 138-148, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 138-148
-
-
Yang, J.Y.1
Zong, C.S.2
Xia, W.3
Yamaguchi, H.4
Ding, Q.5
Xie, X.6
Lang, J.Y.7
Lai, C.C.8
Chang, C.J.9
Huang, W.C.10
Huang, H.11
Kuo, H.P.12
Lee, D.F.13
Li, L.Y.14
Lien, H.C.15
Cheng, X.16
Chang, K.J.17
Hsiao, C.D.18
Tsai, F.J.19
Tsai, C.H.20
Sahin, A.A.21
Muller, W.J.22
Mills, G.B.23
Yu, D.24
Hortobagyi, G.N.25
Hung, M.C.26
more..
-
84
-
-
33744462507
-
Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death
-
Yang KT, Chang WL, Yang PC, Chien CL, Lai MS, Su MJ, Wu ML. Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death. Cell Death Differ 13: 1815-1826, 2006.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1815-1826
-
-
Yang, K.T.1
Chang, W.L.2
Yang, P.C.3
Chien, C.L.4
Lai, M.S.5
Su, M.J.6
Wu, M.L.7
-
86
-
-
77956236877
-
PI3king apart PTEN's role in cancer
-
Zhang S, Yu D. PI3king apart PTEN's role in cancer. Clin Cancer Res 16: 4325-4330, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4325-4330
-
-
Zhang, S.1
Yu, D.2
-
87
-
-
0038521288
-
A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death
-
Zhang W, Chu X, Tong Q, Cheung JY, Conrad K, Masker K, Miller BA. A novel TRPM2 isoform inhibits calcium influx and susceptibility to cell death. J Biol Chem 278: 16222-16229, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 16222-16229
-
-
Zhang, W.1
Chu, X.2
Tong, Q.3
Cheung, J.Y.4
Conrad, K.5
Masker, K.6
Miller, B.A.7
-
88
-
-
33646415942
-
TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage
-
Zhang W, Hirschler-Laszkiewicz I, Tong Q, Conrad K, Sun SC, Penn L, Barber DL, Stahl R, Carey DJ, Cheung JY, Miller BA. TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage. Am J Physiol Cell Physiol 290: C1146-C1159, 2006.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Zhang, W.1
Hirschler-Laszkiewicz, I.2
Tong, Q.3
Conrad, K.4
Sun, S.C.5
Penn, L.6
Barber, D.L.7
Stahl, R.8
Carey, D.J.9
Cheung, J.Y.10
Miller, B.A.11
-
89
-
-
34250179471
-
Glycogen synthase kinase-3α and-3β mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1
-
Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. Glycogen synthase kinase-3α and-3β mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol 27: 4328-4339, 2007.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4328-4339
-
-
Zhao, Y.1
Altman, B.J.2
Coloff, J.L.3
Herman, C.E.4
Jacobs, S.R.5
Wieman, H.L.6
Wofford, J.A.7
Dimascio, L.N.8
Ilkayeva, O.9
Kelekar, A.10
Reya, T.11
Rathmell, J.C.12
|