Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex

Acta Crystallographica Section D: Biological Crystallography

Volumn 69, Issue 5, 2013, Pages 860-865

  Aggarwal, Mayank ^a   Boone, Christopher D ^a   Kondeti, Bhargav ^a   Tu, Chingkuang ^a   Silverman, David N ^a   McKenna, Robert ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

acetazolamide; carbonic anhydrase; cryoprotectants; glycerol; sucrose

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CRYOPROTECTIVE AGENT; GLYCEROL; SUCROSE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CRYOPROTECTANTS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYME STABILITY; HUMAN; KINETICS; METABOLISM; PROTEIN CONFORMATION; TEMPERATURE; X RAY CRYSTALLOGRAPHY;

ACETAZOLAMIDE; CARBONIC ANHYDRASE; CRYOPROTECTANTS; GLYCEROL; SUCROSE;

ACETAZOLAMIDE; CALORIMETRY, DIFFERENTIAL SCANNING; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CATALYTIC DOMAIN; CRYOPROTECTIVE AGENTS; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; GLYCEROL; HUMANS; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SUCROSE; TEMPERATURE;

EID: 84877274235     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444913002771     Document Type: Article

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