Apo-human carbonic anhydrase II revisited: Implications of the loss of a metal in protein structure, stability, and solvent network

Biochemistry

Volumn 48, Issue 31, 2009, Pages 7365-7372

  Avvaru, Balendu Sankara ^a   Busby, Scott A ^b   Chalmers, Michael J ^b   Griffin, Patrick R ^b   Venkatakrishnan, Balasubramanian ^a   Agbandje McKenna, Mavis ^a   Silverman, David N ^a   McKenna, Robert ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; H/D EXCHANGE; HUMAN CARBONIC ANHYDRASE II; METALLOENZYMES; ORDERED WATER; OUTWARD ORIENTATION; PROTEIN STRUCTURES; PROTON SHUTTLE; SIDE CHAINS; STRUCTURAL FEATURE; THERMAL MOBILITY; THERMAL STABILITY; THERMAL UNFOLDING TRANSITIONS;

AMIDES; ENZYMES; METAL RECOVERY; PROTONS; STRUCTURAL METALS; ZINC;

CHEMICALS REMOVAL (WATER TREATMENT);

APOENZYME; CARBONATE DEHYDRATASE II; ZINC;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL;

APOPROTEINS; CARBONIC ANHYDRASE II; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; HOLOENZYMES; HUMANS; SOLVENTS; STATIC ELECTRICITY; ZINC;

EID: 68249118959     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9007512     Document Type: Article

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