Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Serana, Federico ^a   Chiarini, Marco ^a   Zanotti, Cinzia ^a   Sottini, Alessandra ^a   Bertoli, Diego ^a   Bosio, Andrea ^a   Caimi, Luigi ^b   Imberti, Luisa ^a  

^a Diagnostics Department   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Immunodeficiency; K deleting recombination excision circles; Newborn screening; T cell receptor excision circles

Indexed keywords

B LYMPHOCYTE RECEPTOR; IMMUNOGLOBULIN KAPPA CHAIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; B LYMPHOCYTE; CELLULAR IMMUNITY; DISEASE MARKER; DNA STRUCTURE; ENZYME REPLACEMENT; FLOW CYTOMETRY; GENE; GENE LOCUS; GENETIC DISORDER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; IMMUNOGLOBULIN KAPPA GENE; KAPPA DELETING RECOMBINATION EXCISION CIRCLE; LYMPHOCYTE SUBPOPULATION; NEWBORN SCREENING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; STEM CELL TRANSPLANTATION; T CELL RECEPTOR EXCISION CIRCLE; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN GENE;

ADULT; ANTI-RETROVIRAL AGENTS; B-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; DNA, CIRCULAR; FLOW CYTOMETRY; HIV INFECTIONS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFANT; INFANT, NEWBORN; NEONATAL SCREENING; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; RECOMBINATION, GENETIC; STEM CELL TRANSPLANTATION; STEM CELLS; T-LYMPHOCYTES; V(D)J RECOMBINATION;

EID: 84877149190     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-119     Document Type: Review

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