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Volumn 12, Issue 9, 2013, Pages 1424-1432

Radiation-induced cellular senescence results from a slippage of long-term G2 arrested cells into G1 phase

Author keywords

Cell cycle checkpoint; DNA damage response; Ionizing radiation; Mitotic slippage; Senescence

Indexed keywords

AURORA A KINASE; CAVEOLIN 1; CYCLIN B1; CYCLIN D1; POLO LIKE KINASE 1; PROTEIN TYROSINE PHOSPHATASE;

EID: 84877115361     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.24528     Document Type: Article
Times cited : (40)

References (48)
  • 1
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • PMID:2342578
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990; 345:458-60; PMID:2342578; http://dx.doi.org/10. 1038/345458a0
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 2
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • PMID:18323444
    • Halazonetis TD, Gorgoulis VG, Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008; 319:1352-5; PMID:18323444; http://dx.doi.org/10.1126/science.1140735
    • (2008) Science , vol.319 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 3
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • PMID:16079851
    • Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005; 436:725-30; PMID:16079851; http://dx.doi.org/10. 1038/nature03918
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1    Trotman, L.C.2    Shaffer, D.3    Lin, H.K.4    Dotan, Z.A.5    Niki, M.6
  • 4
    • 0038013875 scopus 로고    scopus 로고
    • Senescence, apoptosis and therapy-cutting the lifelines of cancer
    • PMID:12671667
    • Schmitt CA. Senescence, apoptosis and therapy-cutting the lifelines of cancer. Nat Rev Cancer 2003; 3:286-95; PMID:12671667; http://dx.doi.org/10.1038/ nrc1044
    • (2003) Nat Rev Cancer , vol.3 , pp. 286-295
    • Schmitt, C.A.1
  • 5
    • 84859483420 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin
    • PMID:22278880
    • Velarde MC, Flynn JM, Day NU, Melov S, Campisi J. Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY) 2012; 4:3-12; PMID:22278880
    • (2012) Aging (Albany NY) , vol.4 , pp. 3-12
    • Velarde, M.C.1    Flynn, J.M.2    Day, N.U.3    Melov, S.4    Campisi, J.5
  • 6
    • 33750030758 scopus 로고    scopus 로고
    • The regulation of INK4/ARF in cancer and aging
    • PMID:17055429
    • Kim WY, Sharpless NE. The regulation of INK4/ARF in cancer and aging. Cell 2006; 127:265-75; PMID:17055429; http://dx.doi.org/10.1016/j.cell.2006.10. 003
    • (2006) Cell , vol.127 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.E.2
  • 7
    • 0037452888 scopus 로고    scopus 로고
    • Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci
    • PMID:12626749
    • Zhang H, Pan KH, Cohen SN. Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci. Proc Natl Acad Sci USA 2003; 100:3251-6; PMID:12626749; http://dx.doi.org/10.1073/pnas.2627983100
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3251-3256
    • Zhang, H.1    Pan, K.H.2    Cohen, S.N.3
  • 8
    • 45849099050 scopus 로고    scopus 로고
    • Living on a break: Cellular senescence as a DNA-damage response
    • PMID:18574463
    • d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer 2008; 8:512-22; PMID:18574463; http://dx.doi.org/10.1038/nrc2440
    • (2008) Nat Rev Cancer , vol.8 , pp. 512-522
    • D'Adda Di Fagagna, F.1
  • 9
    • 0016246216 scopus 로고
    • Proliferative capacity and DNA content of aging human diploid cells in culture: A cytophotometric and autoradiographic analysis
    • PMID:4612051
    • Yanishevsky R, Mendelsohn ML, Mayall BH, Cristofalo VJ. Proliferative capacity and DNA content of aging human diploid cells in culture: a cytophotometric and autoradiographic analysis. J Cell Physiol 1974; 84:165-70; PMID:4612051; http://dx.doi.org/10.1002/jcp.1040840202
    • (1974) J Cell Physiol , vol.84 , pp. 165-170
    • Yanishevsky, R.1    Mendelsohn, M.L.2    Mayall, B.H.3    Cristofalo, V.J.4
  • 10
    • 0016299205 scopus 로고
    • DNA microdensitometry as a measure of cycling-non-cycling activity in aged human diploid cells in culture
    • PMID:4140976
    • Grove GL, Mitchell RB. DNA microdensitometry as a measure of cycling-non-cycling activity in aged human diploid cells in culture. Mech Ageing Dev 1974; 3:235-40; PMID:4140976; http://dx.doi.org/10.1016/0047-6374(74)90019- 0
    • (1974) Mech Ageing Dev , vol.3 , pp. 235-240
    • Grove, G.L.1    Mitchell, R.B.2
  • 11
    • 0017615459 scopus 로고
    • Characterization of the cell cycle of cultured human diploid cells: Effects of aging and hydrocortisone
    • PMID:856836
    • Grove GL, Cristofalo VJ. Characterization of the cell cycle of cultured human diploid cells: effects of aging and hydrocortisone. J Cell Physiol 1977; 90:415-22; PMID:856836; http://dx.doi.org/10.1002/jcp.1040900305
    • (1977) J Cell Physiol , vol.90 , pp. 415-422
    • Grove, G.L.1    Cristofalo, V.J.2
  • 12
    • 77953810029 scopus 로고    scopus 로고
    • P53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress
    • PMID:20383190
    • Wiebusch L, Hagemeier C. p53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress. Oncogene 2010; 29:3477-89; PMID:20383190; http://dx.doi.org/10.1038/onc.2010.99
    • (2010) Oncogene , vol.29 , pp. 3477-3489
    • Wiebusch, L.1    Hagemeier, C.2
  • 13
    • 84865038079 scopus 로고    scopus 로고
    • Replicatively senescent cells are arrested in G1 and G2 phases
    • PMID:22745179
    • Mao Z, Ke Z, Gorbunova V, Seluanov A. Replicatively senescent cells are arrested in G1 and G2 phases. Aging (Albany NY) 2012; 4:431-5; PMID:22745179
    • (2012) Aging (Albany NY) , vol.4 , pp. 431-435
    • Mao, Z.1    Ke, Z.2    Gorbunova, V.3    Seluanov, A.4
  • 14
    • 0028845640 scopus 로고
    • What is the restriction point?
    • PMID:8608014
    • Zetterberg A, Larsson O, Wiman KG. What is the restriction point? Curr Opin Cell Biol 1995; 7:835-42; PMID:8608014; http://dx.doi.org/10.1016/0955- 0674(95)80067-0
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 835-842
    • Zetterberg, A.1    Larsson, O.2    Wiman, K.G.3
  • 15
    • 0035926571 scopus 로고    scopus 로고
    • Regulation of the eukaryotic cell cycle: Molecular antagonism, hysteresis, and irreversible transitions
    • PMID:11371178
    • Tyson JJ, Novak B. Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions. J Theor Biol 2001; 210:249-63; PMID:11371178; http://dx.doi.org/10.1006/jtbi.2001.2293
    • (2001) J Theor Biol , vol.210 , pp. 249-263
    • Tyson, J.J.1    Novak, B.2
  • 16
    • 34347381069 scopus 로고    scopus 로고
    • Irreversible cell-cycle transitions are due to systems-level feedback
    • PMID:17603504
    • Novak B, Tyson JJ, Gyorffy B, Csikasz-Nagy A. Irreversible cell-cycle transitions are due to systems-level feedback. Nat Cell Biol 2007; 9:724-8; PMID:17603504; http://dx.doi.org/10.1038/ncb0707-724
    • (2007) Nat Cell Biol , vol.9 , pp. 724-728
    • Novak, B.1    Tyson, J.J.2    Gyorffy, B.3    Csikasz-Nagy, A.4
  • 17
    • 79959555511 scopus 로고    scopus 로고
    • Cubism and the cell cycle: The many faces of the APC/C
    • PMID:21633387
    • Pines J. Cubism and the cell cycle: the many faces of the APC/C. Nat Rev Mol Cell Biol 2011; 12:427-38; PMID:21633387; http://dx.doi.org/10.1038/nrm3132
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 427-438
    • Pines, J.1
  • 18
    • 0035890165 scopus 로고    scopus 로고
    • Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells
    • PMID:11707420
    • Sudo T, Ota Y, Kotani S, Nakao M, Takami Y, Takeda S, et al. Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. EMBO J 2001; 20:6499-508; PMID:11707420; http://dx.doi.org/10.1093/emboj/20.22.6499
    • (2001) EMBO J , vol.20 , pp. 6499-6508
    • Sudo, T.1    Ota, Y.2    Kotani, S.3    Nakao, M.4    Takami, Y.5    Takeda, S.6
  • 19
    • 47549098471 scopus 로고    scopus 로고
    • The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
    • PMID:18662541
    • Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell 2008; 134:256-67; PMID:18662541; http://dx.doi.org/10.1016/j.cell.2008.05. 043
    • (2008) Cell , vol.134 , pp. 256-267
    • Bassermann, F.1    Frescas, D.2    Guardavaccaro, D.3    Busino, L.4    Peschiaroli, A.5    Pagano, M.6
  • 20
    • 79959416307 scopus 로고    scopus 로고
    • Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G2 checkpoint arrest
    • PMID:20716119
    • Poehlmann A, Habold C, Walluscheck D, Reissig K, Bajbouj K, Ullrich O, et al. Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G2 checkpoint arrest. J Cell Mol Med 2011; 15:1528-41; PMID:20716119; http://dx.doi.org/10.1111/j.1582-4934.2010.01143.x
    • (2011) J Cell Mol Med , vol.15 , pp. 1528-1541
    • Poehlmann, A.1    Habold, C.2    Walluscheck, D.3    Reissig, K.4    Bajbouj, K.5    Ullrich, O.6
  • 21
    • 33744996707 scopus 로고    scopus 로고
    • Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint
    • PMID:16782009
    • Brito DA, Rieder CL. Mitotic checkpoint slippage in humans occurs via cyclin B destruction in the presence of an active checkpoint. Curr Biol 2006; 16:1194-200; PMID:16782009; http://dx.doi.org/10.1016/j.cub.2006.04.043
    • (2006) Curr Biol , vol.16 , pp. 1194-1200
    • Brito, D.A.1    Rieder, C.L.2
  • 22
    • 79955603408 scopus 로고    scopus 로고
    • Cell cycle suspension: A novel process lurking in G2 arrest
    • PMID:21455017
    • He J, Li J, Ye C, Zhou L, Zhu J, Wang J, et al. Cell cycle suspension: a novel process lurking in G2 arrest. Cell Cycle 2011; 10:1468-76; PMID:21455017; http://dx.doi.org/10.4161/cc.10.9.15510
    • (2011) Cell Cycle , vol.10 , pp. 1468-1476
    • He, J.1    Li, J.2    Ye, C.3    Zhou, L.4    Zhu, J.5    Wang, J.6
  • 23
    • 0141733088 scopus 로고    scopus 로고
    • Degradation of cyclin B is required for the onset of anaphase in Mammalian cells
    • PMID:12865421
    • Chang DC, Xu N, Luo KQ. Degradation of cyclin B is required for the onset of anaphase in Mammalian cells. J Biol Chem 2003; 278:37865-73; PMID:12865421; http://dx.doi.org/10.1074/jbc.M306376200
    • (2003) J Biol Chem , vol.278 , pp. 37865-37873
    • Chang, D.C.1    Xu, N.2    Luo, K.Q.3
  • 24
    • 4143080409 scopus 로고    scopus 로고
    • Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells
    • PMID:15208674
    • Yuan J, Yan R, Krämer A, Eckerdt F, Roller M, Kaufmann M, et al. Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells. Oncogene 2004; 23:5843-52; PMID:15208674; http://dx.doi.org/10.1038/sj. onc.1207757
    • (2004) Oncogene , vol.23 , pp. 5843-5852
    • Yuan, J.1    Yan, R.2    Krämer, A.3    Eckerdt, F.4    Roller, M.5    Kaufmann, M.6
  • 25
    • 23044514962 scopus 로고    scopus 로고
    • Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sisterchromatid cohesion
    • PMID:15958495
    • Hou F, Zou H. Two human orthologues of Eco1/Ctf7 acetyltransferases are both required for proper sisterchromatid cohesion. Mol Biol Cell 2005; 16:3908-18; PMID:15958495; http://dx.doi.org/10.1091/mbc.E04-12-1063
    • (2005) Mol Biol Cell , vol.16 , pp. 3908-3918
    • Hou, F.1    Zou, H.2
  • 26
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 protein: From the known and the unknown
    • PMID:10653597
    • Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol 2000; 182:311-22; PMID:10653597; http://dx.doi.org/10.1002/(SICI) 1097-4652(200003)182:3<311::AIDJCP1>3.0.CO;2-9
    • (2000) J Cell Physiol , vol.182 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 27
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: A machine designed to destroy
    • PMID:16896351
    • Peters JM. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 2006; 7:644-56; PMID:16896351; http://dx.doi.org/10.1038/nrm1988
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 644-656
    • Peters, J.M.1
  • 28
    • 0032588186 scopus 로고    scopus 로고
    • NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • PMID:10409765
    • Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS Jr. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 1999; 19:5785-99; PMID:10409765
    • (1999) Mol Cell Biol , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1    Albanese, C.2    Reuther, J.Y.3    Pestell, R.G.4    Baldwin Jr., A.S.5
  • 29
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: Regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • PMID:10082535
    • Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, Strauss M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol 1999; 19:2690-8; PMID:10082535
    • (1999) Mol Cell Biol , vol.19 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 30
    • 26844491712 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells
    • PMID:16123159
    • Saitoh M, Ohmichi M, Takahashi K, Kawagoe J, Ohta T, Doshida M, et al. Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells. Endocrinology 2005; 146:4917-25; PMID:16123159; http://dx.doi.org/10.1210/en.2004-1535
    • (2005) Endocrinology , vol.146 , pp. 4917-4925
    • Saitoh, M.1    Ohmichi, M.2    Takahashi, K.3    Kawagoe, J.4    Ohta, T.5    Doshida, M.6
  • 31
    • 84856034758 scopus 로고    scopus 로고
    • Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: A potential mechanism of therapeutic limitation of mTOR inhibitor
    • PMID:22178087
    • Iida S, Miki Y, Ono K, Akahira J, Nakamura Y, Suzuki T, et al. Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor. Mol Cell Endocrinol 2012; 350:99-106; PMID:22178087; http://dx.doi.org/10.1016/j. mce.2011.11.024
    • (2012) Mol Cell Endocrinol , vol.350 , pp. 99-106
    • Iida, S.1    Miki, Y.2    Ono, K.3    Akahira, J.4    Nakamura, Y.5    Suzuki, T.6
  • 32
    • 24344441632 scopus 로고    scopus 로고
    • Decreased caveolin-1 in atheroma: Loss of antiproliferative control of vascular smooth muscle cells in atherosclerosis
    • PMID:15950204
    • Schwencke C, Schmeisser A, Walter C, Wachter R, Pannach S, Weck B, et al. Decreased caveolin-1 in atheroma: loss of antiproliferative control of vascular smooth muscle cells in atherosclerosis. Cardiovasc Res 2005; 68:128-35; PMID:15950204; http://dx.doi.org/10.1016/j.cardiores.2005.05.004
    • (2005) Cardiovasc Res , vol.68 , pp. 128-135
    • Schwencke, C.1    Schmeisser, A.2    Walter, C.3    Wachter, R.4    Pannach, S.5    Weck, B.6
  • 33
    • 0026514995 scopus 로고
    • BTG1, a member of a new family of antiproliferative genes
    • PMID:1373383
    • Rouault JP, Rimokh R, Tessa C, Paranhos G, Ffrench M, Duret L, et al. BTG1, a member of a new family of antiproliferative genes. EMBO J 1992; 11:1663-70; PMID:1373383
    • (1992) EMBO J , vol.11 , pp. 1663-1670
    • Rouault, J.P.1    Rimokh, R.2    Tessa, C.3    Paranhos, G.4    Ffrench, M.5    Duret, L.6
  • 34
    • 0032744493 scopus 로고    scopus 로고
    • Cell cycle-regulated proteolysis of mitotic target proteins
    • PMID:10564281
    • Bastians H, Topper LM, Gorbsky GL, Ruderman JV. Cell cycle-regulated proteolysis of mitotic target proteins. Mol Biol Cell 1999; 10:3927-41; PMID:10564281
    • (1999) Mol Biol Cell , vol.10 , pp. 3927-3941
    • Bastians, H.1    Topper, L.M.2    Gorbsky, G.L.3    Ruderman, J.V.4
  • 35
    • 36749082267 scopus 로고    scopus 로고
    • Cell cycle markers in clinical oncology
    • PMID:18032010
    • Williams GH, Stoeber K. Cell cycle markers in clinical oncology. Curr Opin Cell Biol 2007; 19:672-9; PMID:18032010; http://dx.doi.org/10.1016/j.ceb. 2007.10.005
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 672-679
    • Williams, G.H.1    Stoeber, K.2
  • 36
    • 84870694131 scopus 로고    scopus 로고
    • Endoreplication and polyploidy: Insights into development and disease
    • PMID:23222436
    • Fox DT, Duronio RJ. Endoreplication and polyploidy: insights into development and disease. Development 2013; 140:3-12; PMID:23222436; http://dx.doi.org/10.1242/dev.080531
    • (2013) Development , vol.140 , pp. 3-12
    • Fox, D.T.1    Duronio, R.J.2
  • 37
    • 0035805201 scopus 로고    scopus 로고
    • Endoreplication cell cycles: More for less
    • PMID:11348589
    • Edgar BA, Orr-Weaver TL. Endoreplication cell cycles: more for less. Cell 2001; 105:297-306; PMID:11348589; http://dx.doi.org/10.1016/S0092-8674(01) 00334-8
    • (2001) Cell , vol.105 , pp. 297-306
    • Edgar, B.A.1    Orr-Weaver, T.L.2
  • 38
    • 0028171096 scopus 로고
    • Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
    • PMID:7962060
    • Andreassen PR, Margolis RL. Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells. J Cell Biol 1994; 127:789-802; PMID:7962060; http://dx.doi.org/10.1083/jcb.127.3.789
    • (1994) J Cell Biol , vol.127 , pp. 789-802
    • Andreassen, P.R.1    Margolis, R.L.2
  • 39
    • 77953120076 scopus 로고    scopus 로고
    • Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1
    • PMID:20379221
    • Alvarez-Fernández M, Halim VA, Krenning L, Aprelia M, Mohammed S, Heck AJ, et al. Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1. EMBO Rep 2010; 11:452-8; PMID:20379221; http://dx.doi.org/10.1038/embor.2010.46
    • (2010) EMBO Rep , vol.11 , pp. 452-458
    • Alvarez-Fernández, M.1    Halim, V.A.2    Krenning, L.3    Aprelia, M.4    Mohammed, S.5    Heck, A.J.6
  • 40
    • 70350629054 scopus 로고    scopus 로고
    • Endoreplication: Polyploidy with purpose
    • PMID:19884253
    • Lee HO, Davidson JM, Duronio RJ. Endoreplication: polyploidy with purpose. Genes Dev 2009; 23:2461-77; PMID:19884253; http://dx.doi.org/10.1101/ gad.1829209
    • (2009) Genes Dev , vol.23 , pp. 2461-2477
    • Lee, H.O.1    Davidson, J.M.2    Duronio, R.J.3
  • 41
    • 0035210988 scopus 로고    scopus 로고
    • Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cells
    • PMID:11731454
    • Deng WM, Althauser C, Ruohola-Baker H. Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cells. Development 2001; 128:4737-46; PMID:11731454
    • (2001) Development , vol.128 , pp. 4737-4746
    • Deng, W.M.1    Althauser, C.2    Ruohola-Baker, H.3
  • 42
    • 0033532069 scopus 로고    scopus 로고
    • Thrombopoietin signal transduction requires functional JAK2, not TYK2
    • PMID:10224114
    • Drachman JG, Millett KM, Kaushansky K. Thrombopoietin signal transduction requires functional JAK2, not TYK2. J Biol Chem 1999; 274:13480-4; PMID:10224114; http://dx.doi.org/10.1074/jbc.274.19.13480
    • (1999) J Biol Chem , vol.274 , pp. 13480-13484
    • Drachman, J.G.1    Millett, K.M.2    Kaushansky, K.3
  • 43
    • 58149357077 scopus 로고    scopus 로고
    • Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells
    • PMID:19147015
    • Scharpfenecker M, Kruse JJ, Sprong D, Russell NS, Ten Dijke P, Stewart FA. Ionizing radiation shifts the PAI-1/ID-1 balance and activates notch signaling in endothelial cells. Int J Radiat Oncol Biol Phys 2009; 73:506-13; PMID:19147015; http://dx.doi.org/10.1016/j.ijrobp.2008.09.052
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 506-513
    • Scharpfenecker, M.1    Kruse, J.J.2    Sprong, D.3    Russell, N.S.4    Ten Dijke, P.5    Stewart, F.A.6
  • 44
    • 45149097650 scopus 로고    scopus 로고
    • Global control of cell-cycle transcription by coupled CDK and network oscillators
    • PMID:18463633
    • Orlando DA, Lin CY, Bernard A, Wang JY, Socolar JE, Iversen ES, et al. Global control of cell-cycle transcription by coupled CDK and network oscillators. Nature 2008; 453:944-7; PMID:18463633; http://dx.doi.org/10.1038/ nature06955
    • (2008) Nature , vol.453 , pp. 944-947
    • Orlando, D.A.1    Lin, C.Y.2    Bernard, A.3    Wang, J.Y.4    Socolar, J.E.5    Iversen, E.S.6
  • 45
    • 0033598334 scopus 로고    scopus 로고
    • Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle
    • PMID:10517640
    • Haase SB, Reed SI. Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle. Nature 1999; 401:394-7; PMID:10517640; http://dx.doi.org/10.1038/43927
    • (1999) Nature , vol.401 , pp. 394-397
    • Haase, S.B.1    Reed, S.I.2
  • 46
    • 84862821535 scopus 로고    scopus 로고
    • Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network
    • PMID:22306294
    • Simmons Kovacs LA, Mayhew MB, Orlando DA, Jin Y, Li Q, Huang C, et al. Cyclin-dependent kinases are regulators and effectors of oscillations driven by a transcription factor network. Mol Cell 2012; 45:669-79; PMID:22306294; http://dx.doi.org/10.1016/j.molcel.2011.12.033
    • (2012) Mol Cell , vol.45 , pp. 669-679
    • Simmons Kovacs, L.A.1    Mayhew, M.B.2    Orlando, D.A.3    Jin, Y.4    Li, Q.5    Huang, C.6
  • 47
    • 0347762556 scopus 로고    scopus 로고
    • From polyploidy to aneuploidy, genome instability and cancer
    • PMID:14708009
    • Storchova Z, Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol 2004; 5:45-54; PMID:14708009; http://dx.doi.org/10.1038/nrm1276
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 45-54
    • Storchova, Z.1    Pellman, D.2
  • 48
    • 45849116227 scopus 로고    scopus 로고
    • Genetic stability of senescence reverted cells: Genome reduction division of polyploidy cells, aneuploidy and neoplasia
    • PMID:18469530
    • Walen KH. Genetic stability of senescence reverted cells: genome reduction division of polyploidy cells, aneuploidy and neoplasia. Cell Cycle 2008; 7:1623-9; PMID:18469530; http://dx.doi.org/10.4161/cc.7.11.5964
    • (2008) Cell Cycle , vol.7 , pp. 1623-1629
    • Walen, K.H.1


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