Thrombopoietin signal transduction requires functional JAK2, not TYK2

Journal of Biological Chemistry

Volumn 274, Issue 19, 1999, Pages 13480-13484

  Drachman, Jonathan G ^a,b   Millett, Kelly M ^a   Kaushansky, Kenneth ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b PUGET SOUND BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; STAT3 PROTEIN; THROMBOPOIETIN; TYROSINE;

ARTICLE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOMA CELL; SIGNAL TRANSDUCTION;

BASE SEQUENCE; DNA PRIMERS; DNA-BINDING PROTEINS; HUMANS; JANUS KINASE 2; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; THROMBOPOIETIN; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; TYK2 KINASE; TYROSINE;

EID: 0033532069     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.19.13480     Document Type: Article

References (30)

1. Ihle, J. N. (1995) Nature 377, 591-594
2. Ihle, J. N. (1996) Philos. Trans. R. Soc. Lond. B Biol. Sci. 351, 159-166
3. Murakami, M., Narazaki, M., Hibi, M., Yawata, H., Yasukawa, K., Hamaguchi, M., Taga, T., and Kishimoto, T. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 11349-11353
4. Leaman, D. W., Leung, S., Li, X., and Stark, G. R. (1996) FASEB J. 10, 1578-1588
5. Briseoe, J., Guschin, D., Rogers, N. C., Watling, D., Muller, M., Horn, F., Heinrich, P., Stark, G. R., and Kerr, I. M. (1996) Philos. Trans. R. Soc. Lond. B Biol. Sci. 351, 167-171
6. Kaushansky, K., Broudy, V. C., Lin, N., Jorgensen, M. J., McCarty, J., Fox, N., Zucker-Franklin, D., and Lofton-Day, C. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3234-3238
7. Broudy, V. C., Lin, N., Fox, N., Taga, T., Saito, M., and Kaushansky, K. (1995) Blood 88, 2026-2032
8. Courtois, G., Bénit, L., Mikaeloff, Y., Pauchard, M., Charon, M., Varlet, P., and Gisselbrecht, S. (1995) J. Virol. 69, 2794-2800
9. Alexander, W. S., Metcalf, D., and Dunn, A. R. (1995) EMBO J. 14, 5569-5578
10. Skoda, R. C., Seldin, D. C., Chiang, M. K., Peichel, C. L., Vogt, T. F., and Leder, P. (1993) EMBO J. 12, 2645-2653
11. Jin, L., Siritanaratkul, N., Emery, D. W., Richard, R. E., Kaushansky, K., Papayannopoulou, T., and Blau, C. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 8093-8097
12. Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. (1994) Science 264, 1415-1421
13. Sattler, M., Durstin, M. A., Frank, D. A., Okuda, K., Kaushansky, K., Salgia, R., and Griffin, J. D. (1995) Exp. Hematol. 23, 1040-1048
14. Morita, H., Tahara, T., Matsumoto, A., Kato, T., Miyazaki, H., and Ohashi, H. (1996) FEBS Lett. 395, 228-234
15. Ezumi, Y., Takayama, H., and Okuma, M. (1995) FEBS Lett. 374, 48-52
16. Mu, S. X., Xia, M., Elliott, G., Bogenberger, J., Swift, S., Bennett, L., Lappinga, D. L., Hecht, R., Lee, R., and Saris, C. J. (1995) Blood 86, 4532-4543
17. Tortolani, P. J., Johnston, J. A., Bacon, C. M., McVicar, D. W., Shimosaka, A., Linnekin, D., Longo, D. L., and O'Shea, J. J. (1995) Blood 85, 3444-3451
18. Drachman, J. G., Sabath, D. F., Fox, N. E., and Kaushansky, K. (1997) Blood 89, 483-492
19. Guschin, D., Rogers, N., Briscoe, J., Witthuhn, B., Watling, D., Horn, F., Pellegrini, S., Yasukawa, K., Heinrich, P., Stark, G. R., Ihle, J. N., and Kerr, I. M. (1995) EMBO J. 14, 1421-1429
20. Tweardy, D. J., Wright, T. M., Ziegler, S. F., Baumann, H., Chakraborty, A., White, S. M., Dyer, K. F., and Rubin, K. A. (1995) Blood 86, 4409-4416
21. Alexander, W. S., Maurer, A. B., Novak, U., and Harrison-Smith, M. (1996) EMBO J. 15, 6531-6540
22. Drachman, J. G., and Kaushansky, K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2350-2355
23. Hill, R. J., Zozulya, S., Lu, Y. L., Hollenbach, P. W., Joyce Shaikh, B., Bogenberger, J., and Gishizky, M. L. (1996) Cell Growth Differ. 7, 1125-1134
24. Leaman, D. W., Pisharody, S., Flickinger, T. W., Commane, M. A., Schlessinger, J., Kerr, I. M., Levy, D. E., and Stark, G. R. (1996) Mol. Cell. Biol. 16, 369-375
25. Dorsch, M., Fan, P. D., Danial, N. N., Rothman, P. B., and Goff, S. P. (1997) J. Exp. Med. 186, 1947-1955
26. Gurney, A. L., Wong, S. C., Henzel, W. J., and de Sauvage, F. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5292-5296
27. Porteu, F., Rouyez, M. C., Cocault, L., Bénit, L., Charon, M., Picard, F., Gisselbrecht, S., Souyri, M., and Dusanter-Fourt, I. (1996) Mol. Cell. Biol. 16, 2473-2482
28. Morella, K. K., Bruno, E., Kumaki, S., Lai, C. F., Fu, J., Wang, H. M., Murray, L., Hoffman, R., Timour, M., B'enit, L., Gisselbrecht, S., Zhuang, H., Wojchowski, D. M., Baumann, H., and Gearing, D. P. (1995) Blood 86, 557-571
29. Yamashita, Y., Miyazato, A., Shimizu, R., Komatsu, N., Miura, Y., Ozawa, K., and Mano, H. (1997) Exp. Hematol. 25, 211-216
30. Parganas, E., Wang, D., Stravopodis, D., Topham, D. J., Marine, J. C., Teglund, S., Vanin, E. F., Bodner, S., Colamonici, O. R., van Deursen, J. M., Grosveld, G., and Ihle, J. N. (1998) Cell 93, 385-395